Based on bacteriophage resistance mechanisms occurred in nature,a new tactics can be provided and in order to effectively solve the infection problem of bacteriophage by applying genetic engineering technique and establish extensive bacteriophage resistance mechanisms.
This is particularly true for microorganisms known to develop resistance relatively quickly, such asPseudomonas aeruginosa, and resistance mechanisms which occur at a relatively high frequency.
According to different classes of antimycotics there are different resistance mechanisms: differences in the uptake mechanisms, drug target alterations, mostly the ergosterolbiosynthesis pathway, and the efflux or pumping mechanisms to the outside.
This review focuses on the relevant biology of CML, imatinib mesylate resistance mechanisms, and the current status of the next generation of Bcr-Abl inhibitors.
However, most information about leptin-sympathetic actions and leptin-resistance mechanisms derive from in vitro and animal studies.
The emergence of resistance results from the evolution of the sometimes elegant resistance mechanisms that create so-called superbugs, which disseminate by clonal spread or exchange resistance traits with other microorganisms.