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allogeneic bone
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  “allogeneic bone”译为未确定词的双语例句
    Effects of Ly49A transfected lymphocytes on experimental graft versus host disease post allogeneic bone marrow transplantation
    转移杀伤细胞抑制性受体Ly49A的淋巴细胞对异基因骨髓移植后移植物抗宿主病的作用
短句来源
    Study on the Role of Natural Killer Cells in Mouse Allogeneic Bone Marrow Transplantation and Its Mechanism
    自然杀伤细胞在小鼠异基因骨髓移植中作用及其机制的研究
短句来源
    Allogeneic bone marrow transplantation in children (Six cases report)
    小儿异基因骨髓移植六例报告
短句来源
    Effect of Oleanolic acid on immunological reconstitution of allogeneic bone marrow transplantation in mice
    齐墩果酸对小鼠异基因骨髓移植免疫重建的影响
短句来源
    The effect of lcymphokine-activated bone marrow cells on allogeneic bone marrow transplantation in mice
    淋巴因子激活的骨髓细胞对小鼠同种异体骨髓移植的影响
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  allogeneic bone
Special risk factors analyzed are respiratory failure requiring mechanical ventilation, allogeneic bone marrow transplantation, or development of multiple organ failure.
      
To assess the cost-effect relationship of aciclovir prophylaxis versus early treatment, we performed a retrospective study in 44 allogeneic bone marrow transplant recipients, who had only received aciclovir for therapeutic purposes.
      
Infectious complications after allogeneic bone marrow transplantation with and without T-cell depletion of donor marrow
      
C-reactive protein in the management of children with fever after allogeneic bone marrow transplantation
      
This infection was acquired during a period of severe neutropenia after chemotherapy for relapsed acute myelogenous leukemia following allogeneic bone marrow transplantation.
      
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From July, 1985 to December, 1991 , six children (4 cases with B-thalassemia and 2 with aplastic anemia) underwent allogeneic bone marrow transplantation in our hospital. Their ages were from 11 months to 10 years. One had HLA-identical sibling donor and others had haplotype or one HLA antigen mismatched donors. Functional graft was documented in 3 cases. One case had disease free for eight years. The factors of successful engraftment, including the degree of HLA compatibility, the intensity of pretreatment...

From July, 1985 to December, 1991 , six children (4 cases with B-thalassemia and 2 with aplastic anemia) underwent allogeneic bone marrow transplantation in our hospital. Their ages were from 11 months to 10 years. One had HLA-identical sibling donor and others had haplotype or one HLA antigen mismatched donors. Functional graft was documented in 3 cases. One case had disease free for eight years. The factors of successful engraftment, including the degree of HLA compatibility, the intensity of pretreatment regimen and the preventing and treating of GVHD and infections, are discussed.

对4例重症β地中海贫血患儿及2例重症再生障碍性贫血患儿进行异基因骨髓移植,患者年龄11个月至10岁。供受者HLA全相合1例,亲子之间半相合或1个位点不相合5例。3例术后查得植活证据,持久性植活,1例长期无病生存。对影响植入的因素,如HLA匹配程度、预处理方案、移植物抗宿主病及感染的防治措施及小儿骨髓移植中的一些问题进行了讨论。

The T-cell- depleted allogeneic bone marrow transplantation (ABMT) successfully reconstituted the immunological function of the lethally irradiated mice. But the recovery was slow. However, in the Oleanolic acid (OLA) administrated group, the PFC and mitogenic responses were significantly increased and with a tendency to improve DTH response. Further investigation revealed that the IL-2 production of ABMT mice was seriously impaired, but after OLA administration, the production was significantly improved....

The T-cell- depleted allogeneic bone marrow transplantation (ABMT) successfully reconstituted the immunological function of the lethally irradiated mice. But the recovery was slow. However, in the Oleanolic acid (OLA) administrated group, the PFC and mitogenic responses were significantly increased and with a tendency to improve DTH response. Further investigation revealed that the IL-2 production of ABMT mice was seriously impaired, but after OLA administration, the production was significantly improved. Furthermore, the supernatant of the splenocyte culture of ABMT mice was able to inhibite nonspecificly the mixed lymphocyte reactions. After nemoval of the T cells, the supernatant lost its inhibitory effect. In OLA administrated group, there was a tendency of decreasing the inhibitory effect.

用去T细胞异基因骨髓成功地重建了致死量照射小鼠的免疫功能,但移植后受体鼠免疫功能恢复缓慢。给齐墩果酸(OLA)后,受体鼠淋巴细胞增殖反应及空斑形成细胞(PFC)反应增强,明显促进白细胞介素2的产生,迟发性超敏反应(DTH)也有增强趋势;受体鼠脾细胞培养上清液有明显的非特异性免疫抑制作用,去T细胞后抑制作用消失,给OLA后,这一抑制作用有减弱的趋势。

reparative regimen with high dose chemoradio-thera py before allogeneic bone marrow tran splantation(allo-BMT ) is toxic to marrow recipients。Our prepara-tive regimen consists of cyclophosphamide l.8g·m ̄(-2)/dfor 2 days,CCNU 200 mg·m ̄(-2)/d or me-CCNU250mg·m ̄(-2)/d for one day and total hixly irradiation(TBI)of 6.6~7.7 Gy, To evaluate regimen-related tox-icity,we carried Out a retrospective study concerning100 patients conditioned with this regimen. All patientsreceived graft versus host disease(GVHD)...

reparative regimen with high dose chemoradio-thera py before allogeneic bone marrow tran splantation(allo-BMT ) is toxic to marrow recipients。Our prepara-tive regimen consists of cyclophosphamide l.8g·m ̄(-2)/dfor 2 days,CCNU 200 mg·m ̄(-2)/d or me-CCNU250mg·m ̄(-2)/d for one day and total hixly irradiation(TBI)of 6.6~7.7 Gy, To evaluate regimen-related tox-icity,we carried Out a retrospective study concerning100 patients conditioned with this regimen. All patientsreceived graft versus host disease(GVHD) prophylaxis.Regimen-related toxicity was graded according to theseattle's transplantation toxicity system. Morbidity wasassessed in eight organs:heart,bladder,kidneys,lungs,liver,mucosa,centraI nervous system and gut.Toxicity was graded on days 0,7,14 and 28 after trans-plantation,from grade 0(no toxicity)to grade IV(fataltoxicity).Fifteen patients did not show any toxicity.Grades III-IV toxicity were uncommon(10%).The in-dividual organ toxicity was stomatitis(52%),gastroin-testinaI toxicity(36%),cardiac toxicity(25%),bladdertoxicity(20%),hepatic toxicity(19%),central ner-vous system(CNS)toxicity(9%)and pulmonary andrenal toxicity(0%).Bladder toxicity occlired more com-mon in patients who received cyclophosphamide and/orbulsulfan before BMT. Cardiac toxicity was frequent a-mong recipients who received DNR before BMT.Prostaglandin E_1 could reduce the incidence of bladdertoxicity.

报告100例异基因骨髓移植的预处理相关毒性。预处理方案为标准剂量的环磷酰胺、环已亚硝脲(或甲基环已亚硝脲)及全身照射。毒性分级用Bearman等订的标准。结果:15例无任何毒性发生,最大毒性为III~IV级者占10%;各脏器预处理相关毒性发生率为:口腔粘膜52%、胃肠道36%、心脏25%、膀胱20%、肝脏19%、中枢神经系统9%、肺及肾均无近期毒性发生。既往化疗用过柔红霉素者心脏的预处理相关毒性发生率高;既往用过马利兰和(或)CTX可使膀胱的预处理相关毒性发生率增加;而预防性地应用前列腺素E_1可有效地减少膀胱毒性。

 
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