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microvessel density     
相关语句
  微血管密度
     Relationship between overexpression of p53 protein and intratumoral microvessel density in osteosarcoma
     骨肉瘤p53蛋白过度表达与微血管密度的关系
短句来源
     The microvessel density of E21 hippocampus was increased and the structural abnormalities of blood capillary at P30 hippocampus were showed.
     E21海马微血管密度增高,P30海马毛细血管结构异常。
短句来源
     The microvessel density of E21 hippocampus reached a normal level and the blood capillary ultrastructure of P30 hippocampus was restored.
     E21海马微血管密度达到正常水平,P30海马毛细血管结构正常。
短句来源
     Objective To investigate the relationship of microvessel density (MVD) and thrombosondin-1(TSP-1) expression and the biological behaviors for non-small cell lung cancer(NSCLC).
     目的研究微血管密度(MVD)和血小板凝集素1(Thrombospondin-1,TSP-1)的表达与非小细胞肺癌(NSCLC)组织生物学行为的关系。
短句来源
     Liver metastasis rate and tumor foci in liver were counted. Tumor microvessel density(MVD) and vascular endothelial growth factor(VEGF),and base fibroblast growth factor(bFGF) were determined by the immunohistochemistry SABC method with an image analysis system.
     采用免疫组化SABC法和图像分析系统对肝转移肿瘤组织的微血管密度(microvessel density,MVD)、血管内皮生长因子(vascular endothelial growth factor,VEGF)、碱性成纤维细胞生长因子(base fibroblast growth factor,bFGF)的表达进行定量分析。 结果:各组转移率依次下降,差异有统计学意义(P<0.01);
短句来源
更多       
  血管密度
     Microvessel density was significantly higher in VEGF positive tumor (13 905±7 24) than in VEGF negative tumors (6 50±2 10) ( P <0 05). With VEGF positive intensity increasing,microvessel density become more high.
     VEGF 表达阳性胃癌组织的血管密度(13-91 ±7-24) 显著高于VEGF表达阴性者(6-50 ±2-10)( P< 0-05) ,而且随着VEGF表达强度的增强,癌组织内血管密度明显增加。
短句来源
     Results Microvessel density(MVD) and VEGF expression were significantly higher in MCF-7/HER-2 xenograft tumors than that in MCF-7 xenogra ft tumors.
     结果 MCF -7/HER -2移植瘤与MCF -7移植瘤相比血管密度较大 ,VEGF表达增强 ;
短句来源
     Methods: Fifty-eight cases of colorectal cancer and 12 cases of normal colorectal tissue were studied by immunohistochemical method using anti-VEGF-C, Flt-4 and CD34 antibodies. Assessment of lymphatic and blood micro vessel density (LMVD and MVD) were performed.
     方法:对58例大肠癌组织及12例正常肠黏膜进行VEGF-C、Flt-4及CD34免疫组织化学染色,并计数微淋巴管密度(LMVD)和血管密度(MVD)。
短句来源
     Results:VEGF staining was positive in 39 tumors(56.5%)in which the CD34-positive microvessels was significantly higher than that in VEGF-negative 30 tumors ( P <0.05),and multivariate analysis indicated that microvessel density(MVD)and VEGF expression were closely correlated with patients' poor prognosis as well as metastasis.
     结果 :在 3 9例 (5 6.5 % )VEGF表达阳性的标本中 ,CD3 4染色阳性的肿瘤微血管密度 (MVD)明显较 3 0例VEGF表达阴性的血管密度高 (P <0 .0 5 )。
短句来源
     Microvessel density (MVD) was counted by endothelial cells immunostained by anti-CD34 antibody.
     CD34标记血管内皮细胞测定肿瘤的为血管密度(MVD);
短句来源
更多       
  微血管密度
     Relationship between overexpression of p53 protein and intratumoral microvessel density in osteosarcoma
     骨肉瘤p53蛋白过度表达与微血管密度的关系
短句来源
     The microvessel density of E21 hippocampus was increased and the structural abnormalities of blood capillary at P30 hippocampus were showed.
     E21海马微血管密度增高,P30海马毛细血管结构异常。
短句来源
     The microvessel density of E21 hippocampus reached a normal level and the blood capillary ultrastructure of P30 hippocampus was restored.
     E21海马微血管密度达到正常水平,P30海马毛细血管结构正常。
短句来源
     Objective To investigate the relationship of microvessel density (MVD) and thrombosondin-1(TSP-1) expression and the biological behaviors for non-small cell lung cancer(NSCLC).
     目的研究微血管密度(MVD)和血小板凝集素1(Thrombospondin-1,TSP-1)的表达与非小细胞肺癌(NSCLC)组织生物学行为的关系。
短句来源
     Liver metastasis rate and tumor foci in liver were counted. Tumor microvessel density(MVD) and vascular endothelial growth factor(VEGF),and base fibroblast growth factor(bFGF) were determined by the immunohistochemistry SABC method with an image analysis system.
     采用免疫组化SABC法和图像分析系统对肝转移肿瘤组织的微血管密度(microvessel density,MVD)、血管内皮生长因子(vascular endothelial growth factor,VEGF)、碱性成纤维细胞生长因子(base fibroblast growth factor,bFGF)的表达进行定量分析。 结果:各组转移率依次下降,差异有统计学意义(P<0.01);
短句来源
更多       
  血管密度
     Microvessel density was significantly higher in VEGF positive tumor (13 905±7 24) than in VEGF negative tumors (6 50±2 10) ( P <0 05). With VEGF positive intensity increasing,microvessel density become more high.
     VEGF 表达阳性胃癌组织的血管密度(13-91 ±7-24) 显著高于VEGF表达阴性者(6-50 ±2-10)( P< 0-05) ,而且随着VEGF表达强度的增强,癌组织内血管密度明显增加。
短句来源
     Results Microvessel density(MVD) and VEGF expression were significantly higher in MCF-7/HER-2 xenograft tumors than that in MCF-7 xenogra ft tumors.
     结果 MCF -7/HER -2移植瘤与MCF -7移植瘤相比血管密度较大 ,VEGF表达增强 ;
短句来源
     Methods: Fifty-eight cases of colorectal cancer and 12 cases of normal colorectal tissue were studied by immunohistochemical method using anti-VEGF-C, Flt-4 and CD34 antibodies. Assessment of lymphatic and blood micro vessel density (LMVD and MVD) were performed.
     方法:对58例大肠癌组织及12例正常肠黏膜进行VEGF-C、Flt-4及CD34免疫组织化学染色,并计数微淋巴管密度(LMVD)和血管密度(MVD)。
短句来源
     Results:VEGF staining was positive in 39 tumors(56.5%)in which the CD34-positive microvessels was significantly higher than that in VEGF-negative 30 tumors ( P <0.05),and multivariate analysis indicated that microvessel density(MVD)and VEGF expression were closely correlated with patients' poor prognosis as well as metastasis.
     结果 :在 3 9例 (5 6.5 % )VEGF表达阳性的标本中 ,CD3 4染色阳性的肿瘤微血管密度 (MVD)明显较 3 0例VEGF表达阴性的血管密度高 (P <0 .0 5 )。
短句来源
     Microvessel density (MVD) was counted by endothelial cells immunostained by anti-CD34 antibody.
     CD34标记血管内皮细胞测定肿瘤的为血管密度(MVD);
短句来源
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  microvessel density
Relationship of adrenomedullin expression and microvessel density and prognosis in smooth muscle tumor of uterus
      
The aim of this paper was to investigate the relationship between the expression of adrenomedullin (ADM) and microvessel density (MVD) and prognosis in smooth muscle tumor of uterus.
      
Compared with those in the SO group, the significant increases in microvessel density (MVD) were observed on the 30th and the 180th day after the insertion of the bulk copper (P >amp;lt; 0.05).
      
There was a positive correlation between microvessel density (MVD) and the number of the CD56-positive uNK cells in decidual stroma, and also between the number of the CD56-positive uNK cells and VEGF-A protein expression in the tissue.
      
Antiangiogenic Effects of Radiotherapy but not Initial Microvessel Density Predict Survival in Inoperable Oropharyngeal Squamous
      
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The microvascular density of the adult hippocampal formation was investigated by alkaline phos-phatase stain and morphometry. The results showed that the highest density of microvessel was found in the stratum moleculare than other stratum,while the stratum pyramidale and stratum oriens were high density, mediate density respectively, and the lowest density was found in the stratum lacuno-sum. Among various regions of the hippocampal cortex and gyrus dentata,microvessel density in sector CA2 was the highest,in...

The microvascular density of the adult hippocampal formation was investigated by alkaline phos-phatase stain and morphometry. The results showed that the highest density of microvessel was found in the stratum moleculare than other stratum,while the stratum pyramidale and stratum oriens were high density, mediate density respectively, and the lowest density was found in the stratum lacuno-sum. Among various regions of the hippocampal cortex and gyrus dentata,microvessel density in sector CA2 was the highest,in sectors CA3 and CA1 were mederate,and in sector gyrus dentata was the lowest. On the microvessel diameter,the stratum pyramidale was the widest (8. 20±2. 1 μm),the stratum oriens was the smallest (7. 12±0. 9μm) ;compared with other sectors,the sector CA2 was the widest (7. 59±1. 8μm),the sector CA4 was the smallest (5. 41±0. 7μm),the difference between them is highly significant (P<0. 01).

用碱性磷酸酶血管染色法对成人海马结构内微血管密度进行了形态计量学研究。结果表明,海马皮质各层的微血管密度,以分子层最高,以下依次为锥体细胞层和多形细胞层,而腔隙层最低。海马皮质各区和齿状回的微血管密度,以CA_2区最高,CA_3和CA_1区居中,CA_4区次之,齿状回最低。微血管直径以海马锥体细胞层最大(8.20±2.1μm),多形细胞层最小(7.12±0.9μm)。CA_2区的微血管直径最大(7.59±1.8μm),CA_4区的微血管直径最小(5.41±0.7μm),两者有明显差异(P<0.01)。

Objective: To study the relationship between overexpression of p53 protein and intratumoral microvessel density (MVD) and their prognostic significance in osteosarcoma. Methods: The expression of p53 protein and MVD count in 80 cases of osteosarcoma were determined with immunohistochemistry and morphometry. Results: The overexpression of p53 protein was significantly associated with MVD count and the two parameters were important in evaluation of the prognosis of osteosarcoma. p53 positivity was the...

Objective: To study the relationship between overexpression of p53 protein and intratumoral microvessel density (MVD) and their prognostic significance in osteosarcoma. Methods: The expression of p53 protein and MVD count in 80 cases of osteosarcoma were determined with immunohistochemistry and morphometry. Results: The overexpression of p53 protein was significantly associated with MVD count and the two parameters were important in evaluation of the prognosis of osteosarcoma. p53 positivity was the most important index to predict the overall survival rate in patients with osteosarcoma. Conclusion: It is indicated that p53 protein involves in angiogenesis and its overexpression is an important angiogenic phenotype in neoplasm. Meanwhile, p53 protein and MVD may be useful prognostic indicators for patients with osteosarcoma.

目的:研究骨肉瘤p53蛋白过度表达与肿瘤内微血管密度(MVD)的关系,以及它们对骨肉瘤预后的影响。方法:应用免疫组化和形态计量的方法检测80例骨肉瘤p53蛋白表达以及MVD计数。结果:p53蛋白过度表达与MVD密切相关,而且两者均为影响骨肉瘤预后的重要因素,依相对危险度大小依次为p53>MVD。结论:结果证实p53基因对MVD有调节作用,p53蛋白过度表达是肿瘤重要的血管生成表型之一。p53蛋白和MVD是判估骨肉瘤预后有价值的生物学指标。

umor angiogenesis and peritumoral lymphatic vessel invasion have recently shown to be related to tumor progression and metastasis in breast, lung and colon cancer. We examined their association with neck lymph node metastasis in squamous cell carcinoma of oral tongue. Sixty patients were reviewed, samples were cut and immunohistochemically stained for factor Ⅷ, UEA-1, Laminin, which allowed the microvessels and lymphatic vessels to be identified and counted per 200× field by light microscope. Lymphatic counts...

umor angiogenesis and peritumoral lymphatic vessel invasion have recently shown to be related to tumor progression and metastasis in breast, lung and colon cancer. We examined their association with neck lymph node metastasis in squamous cell carcinoma of oral tongue. Sixty patients were reviewed, samples were cut and immunohistochemically stained for factor Ⅷ, UEA-1, Laminin, which allowed the microvessels and lymphatic vessels to be identified and counted per 200× field by light microscope. Lymphatic counts in the tissue immediately adjacent to the tumor were higher than those in normal mucosa and muscle (P<001). Local growth of the tumor was accompanied by peritumoral lymphatic proliferation and abundant dilated lymphatic vessels. No intra-tumoral lymphatic vessels were observed. The intratumoral and peritumoral microvessel density was not higher than that of normal mucosa and muscle. Microvessel and lymphatic vessel density did not correlated with neck nodal metastasis by multivariate analysis. This result was in contradistinction to those recently reported for other tumor sites. Our investigation suggested that the important factors involved in nodal metastasis were increased peritumoral lymphatic density, distinct dilatation, and lack of basement membrane.

为探讨肿瘤血管生成、淋巴管增殖、分布变化与舌鳞癌颈淋巴结转移的相关性,利用免疫组化染色方法,以三种抗体(UEA—1、ⅧR:Ag、LN)显示并准确地区分出肿瘤组织和正常组织内的毛细血管与淋巴管。结果:肿瘤内及周边毛细血管未出现增殖。癌周毛细淋巴管密度明显高于舌粘膜和肌肉组织中的淋巴管密度(P<0.01),管腔扩张,缺乏基底膜。肿瘤内未发现有淋巴管。单因素与多因素分析:毛细血管、毛细淋巴管密度的变化与颈淋巴结转移均无显著性差异。

 
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