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acute toxicity     
相关语句
  急性毒性
     Acute Toxicity of Dangshen & Its n-Butanol Extract & Their Effect on the Plasma Level of Corticosterone & ACTH in Mice
     党参及其正丁醇提取物在小鼠的急性毒性和对血浆皮质酮、ACTH含量的影响
短句来源
     The Acute Toxicity and Monomer Determination of “CCQ” and “Oxpara”
     牙髓治疗剂“CCQ”与“OXPARA”的急性毒性和单体含量测定
短句来源
     Acute Toxicity and Toxicokinetics of Methyl Methacrylate
     甲基丙烯酸甲酯的急性毒性和毒物动力学
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     A STUDY OF ACUTE TOXICITY OF MITOXANTRONE
     米托蒽醌的急性毒性研究
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     Acute Toxicity,Testing (LD_(50)) of Chinese Mineral Druga
     中国矿物药的急性毒性(LD_(50))测定
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  急性中毒
     Entertainment settings were the most popular places chosen for ketamine use. 12.7%(90/708) suffered from acute toxicity,13.5% (96/710) had attack activities,40.3%(287/712) had sex impulse, 5.5%(39/705) had violent sex, 12.1%(85/702) suffered from mental disorders.
     12.7%(90/708)曾经经历过滥用氯胺酮导致的急性中毒,13.5%(96/710)发生过与氯胺酮使用相关的攻击他人行为,40.3%(287/712)发生过与使用氯胺酮相关的性冲动,5.5%(39/705)发生过与使用氯胺酮相关的性暴力行为,12.1%(85/702)经历过不同程度的精神障碍。
短句来源
     Vitamin K1 had no effect on the acute toxicity.
     维生素K_1急性中毒无救治效果。
短句来源
     The experimental study about the toxity and changes of biochemical indicator during acute toxicity of Bromoxynil
     溴苯腈急性中毒小鼠毒性及兔生化指标变化的实验研究
     2. To observe the acute toxicity and death of the mice to which calcium nanoparticles were given in maximal dose and obtain the lethal dose 50(LD50) or the maximal tolerance dose (MTD).
     2.观察小鼠一日内给予大剂量钙纳米粒子的急性中毒及死亡情况,得出半数致死量(LD50)或最大耐受量(MTD)。
短句来源
     Safe concentration was 0.77mg/L. In acute toxicity test, the gill filaments was injured badly. The secondary gill lamellae hyperplasia.
     分别为3 62mg/L、3.23 mg/L和3.01 mg/L,安全浓度为0.77 mg/L,急性中毒试验发现,TTPC在3.16 mg/L以上时,主要损伤鱼类鳃丝,能造成鱼类呼吸障碍,其他器官未见明显病理损伤。
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  急性毒性作用
     This study dealed with the acute toxicity of Hg2+,Cd2+,Cu2+,Pb2+ to larval of Cichlasoma managuense.
     试验探讨了Cu2+、Hg2+、Cd2+、Pb2+4种重金属离子对淡水石斑鱼仔鱼的急性毒性作用
短句来源
     Study on the acute toxicity of TCC ( 3,4,4' -Trichlorocarbanilide), TCS (2,2,4'-Trichloro-2'-hydroxydi-phenyl) to protozoa in biological treatment has been conducted.
     研究了TCC(3,4,4′-Trichlorocarbanilde)、TCS(2,2,4′-Trichloro-2′-hydroxydiphenyl)对废水生物处理中的原生动物的急性毒性作用
短句来源
     This paper studies on the acute toxicity of TCC(2,2,4’ Trichlorocarbanilide) and TCS (2,2,4’ Trichloro 2 hydroxydiphenyl)to the Protozoa from biological treatment. The results showed:(1)The 48h LC 50 of TCC to the Protozoa is 25000μg/L, the 48h LC 50 of TCS is 23000μg/L;
     本文研究了TCC(2,2,4’—Trichlorocarbanilide)、TCS(2,2,4’—Trichloro-2-hydroxydiphenyl)对废水生物处理中的原生动物的急性毒性作用,结果表明:(1)TCC对原生动物的48hLC50为25000μg/L,TCS48hLC50为23000μg/L;
短句来源
     RESULTS: The results showed that MCs possessed strong acute toxicity with liver as the target organ, the LD50 was estimated to be 106.7mg/kg (89.1~127.6 mg/kg, mass of dry algal cells / b.w).
     结果:藻毒素具有极强的急性毒性作用,LD50为106.7mg/kg(89.1~127.6 mg/kg,干藻细胞/体重),肝脏是其主要的靶器官。
短句来源
     Result: Yuanmi-D had no apparent acute toxicity on mouse, LD50 >10g/kgBW.
     结果:元秘-D对小鼠无明显的急性毒性作用,LD50>10g/kg体重。
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  急性致毒
     The effects of acute toxicity of Hg2+, Cd2+, Zn2+ , Mn2+ under the condition of aeration postlarvae of Penaeus japonicus Bate have been studied at the temperature of 28±0.5℃.
     在恒温(28±0.5℃)和充气条件下,研究了Hg~(2+)、Cd~(2+)、Zn~(2+)、Mn~(2+)对日本对虾仔虾的急性致毒效应.
短句来源
     As for the larval Apostichopu sjaponnicus, the effective concentration of zinc is 0.10mg/L, and 1.00mg/L is the acute toxicity concentration of zinc.
     0.10mg/L锌浓度为锌对刺参幼虫的影响浓度,而1.00mg/L为锌对刺参幼虫的急性致毒浓度.
短句来源
     Acute toxicity of Cu~(2+) to nauplius of the blue shrimp Penaeus stylirostris
     Cu~(2+)对南美蓝对虾无节幼体的急性致毒研究
短句来源
     Acute Toxicity of Cu~(2+) to the Juvenile of Macrobrachium Nipponense
     Cu~(2+)对日本沼虾幼虾的急性致毒研究
短句来源
     The acute toxicity test of ammonia nitrogen to larvae Macrobrachium rosenbergii was carried out in this paper. The results showed that the semi lethal concentration ( LC 50 ) of 96 h of the fifth zoea stage ( Z 5 ) was 1.14 mg/L, the safety concentration ( SC ) was 0.11 mg/L;
     通过非离子氨氮对罗氏沼虾幼体的急性致毒试验表明:Ⅴ期幼体96h的半致死浓度(LC50)值为1.14mg/L,安全浓度(SC)值为0.11mg/L;
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  acute toxicity
A lower acute toxicity was also observed compared to INH.
      
An explanation is suggested for the higher tuberculostatic activity and lower acute toxicity of some of the isonicotinoylhydrazones as compared to that of INH.
      
The Chinese rare minnow showed more sensitivity to the acute toxicity exposure of nitrobenzene than Medaka.
      
The acute toxicity of Gd-complex in animal has also been tested, and the median lethal dose (LD50) is equal to (468.2±30) mg/kg.
      
Acute toxicity of formalin to the red-tide dinoflagellate Prorocentrum minimum schiller (protozoa, mastigophora)
      
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Acute toxicity experiment consisted of one single intraperitoneal injection, while subacute toxicity experiment consisted of one injection daily for 14 days, of tartar emetic and a subsequent 3-day holding period. The mortality of mice from tartar emetic was observed after concomitant injections of 5 testing drugs (procaine-HCl, sodium phenyl acetate, sodium α α'-dimercaptoadipate, sodium mercaptosuccinate and sodium thiosulfate). The effective detoxicants were mixed up with tartar emetic and then...

Acute toxicity experiment consisted of one single intraperitoneal injection, while subacute toxicity experiment consisted of one injection daily for 14 days, of tartar emetic and a subsequent 3-day holding period. The mortality of mice from tartar emetic was observed after concomitant injections of 5 testing drugs (procaine-HCl, sodium phenyl acetate, sodium α α'-dimercaptoadipate, sodium mercaptosuccinate and sodium thiosulfate). The effective detoxicants were mixed up with tartar emetic and then injected intraperitoneally, once daily for 14 days, to infected mice. The mice were killed after a holding period of another 14 days. Basing on the average number of worms remained in each mouse, the effects of detoxicants on the antibilharzial activity of tartar emetic were compared. The results were as follows: (1) In mice the acute and subacute LD_(50) after intraperitoneal injection of tartar emetic were found to be 38 and 35 mg/kg/day respectively. (2) The mortality of mice from tartar emetic could be markedly reduced by simultaneous injection of procaine, sodium phenyl acetate, sodium α α'-dimercaptoadipate and sodium mercaptosuccinate, while sodium thiosulfate did not afford any protection. (3) Procaine, sodium phenyl acetate, sodium α α'-dimercaptoadipate and sodium mercaptosuccinate did not decrease the therapeutic. activity of tartar emetic, and, moreover, procaine could significantly augment its therapeutic activity against schistosomiasis japonica.

本文叙述了5种药物(盐酸普鲁卡因、苯乙酸钠、aa′-二巯基己二酸钠、巯基丁二酸钠及硫代硫酸钠)对小白鼠腹腔注射吐酒石急性(注射1次,观察3天)及亚急性(注射14天,观察3天)中毒死亡的影响;并将其中有效解毒药分别和吐酒石混合後腹腔注射小鼠14天以治疗日本血吸虫病,然後停药14天解剖,根据平均每鼠余存虫数比较各药对於吐酒石疗效的影响。结果如下: (一)小白鼠腹腔注射吐酒石急性及亚急性LD_(50)分别为38及35毫克/千克/天。 (二)普鲁卡因、苯乙酸钠、aa′-二巯基己二酸钠及巯基丁二酸钠能使小鼠腹腔注射吐酒石急性及亚急性中毒死亡率明显地减低,而硫代硫酸钠则无效。 (三)普鲁卡因、苯乙酸钠、aa′-二巯基己二酸钠及巯基丁二酸钠4种解毒药并不减低吐酒石之疗效,其中普鲁卡因尚能提高吐酒石治疗日本血吸虫病之疗效。

The LD_(50) of ammonium antimony gluconate (AAG) after intraperitoneal injection was 16.8mg/kg for mice fed on a diet containing 0.01% thyroxine, 166mg/kg for mice on a diet containing 0.1% propylthiouracil and 90mg/kg for control mice It is concluded that feeding mice with thyroxine for two weeks significantly increases the susceptibility of the mice to the acute toxicity of AAG, whereas propylthiouracil feeding increases the resistance of the mice. After intraperitoneal injection of Sb~(124)-labelled...

The LD_(50) of ammonium antimony gluconate (AAG) after intraperitoneal injection was 16.8mg/kg for mice fed on a diet containing 0.01% thyroxine, 166mg/kg for mice on a diet containing 0.1% propylthiouracil and 90mg/kg for control mice It is concluded that feeding mice with thyroxine for two weeks significantly increases the susceptibility of the mice to the acute toxicity of AAG, whereas propylthiouracil feeding increases the resistance of the mice. After intraperitoneal injection of Sb~(124)-labelled AAG to normal rats or rats fed thyroxine or propylthiouracil, high radioactivity levels were found in the liver and the gastrointestinal tract (including its contents), while the Sb~(124) levels in the kidney, thyroid, blood, spleen, lung and other tissues were very low. There seems to be no significant difference between the distribution patterns of radioactivity in tissues for the three groups of rats. The excretions of Sb~(124) for the three groups were also similar. It appears that the difference in toxicity of AAG between control rats and rats with altered thyroid function is not explicable by differences in the distribution and excretion of antimony after administration of AAG.

小鼠連續服用甲狀腺素兩週後,對銻銨急性毒性的敏感性顯著增加,而連續服用丙基硫氧嘧啶,則可增加對銻銨急性毒性的耐受性。腹腔注射銻銨於甲狀腺機能亢進狀態,甲狀腺機能不足及正常大鼠後,銻~(124)在组織中分佈的濃度均以肝及胃腸道为最高,腎臟次之,在甲狀腺中的濃度均很低。腹腔注射銻”銨後,銻~(124)的排泄總量三组動物無明顯區别。因此,銻銨對甲狀腺機能亢進狀態,甲狀腺機能不足及正常小鼠毒性的不同,似並非由於注射銻銨後,銻的分佈和排泄不同所致。

The subcutaneous administration of sodium dimercaptosuccinate (SDS) at a dose of 1500 mg/kg immediately after the intraperitoneal injection of trivalent antimonyl ammonium gluconate (AAG) increased the LD_(50) of the latter from 90—112 mg/kg to 1300—1460 mg/kg. The acute toxicity of the latter when injected intravenously in rabbits was also decreased when SDS was administered via the same route. Two hours after the intravenous injection of AAG (containing radioactive antimony) in rabbits, high radioactivity...

The subcutaneous administration of sodium dimercaptosuccinate (SDS) at a dose of 1500 mg/kg immediately after the intraperitoneal injection of trivalent antimonyl ammonium gluconate (AAG) increased the LD_(50) of the latter from 90—112 mg/kg to 1300—1460 mg/kg. The acute toxicity of the latter when injected intravenously in rabbits was also decreased when SDS was administered via the same route. Two hours after the intravenous injection of AAG (containing radioactive antimony) in rabbits, high radioactivity level was found in the liver. The levels in the spleen and the thyroid were very low. Intravenous administration of SDS immediately after the antimonyl decreased the radioactivity level in the liver. Fifteen minutes after the AAG injection, plasma radioactivity was 1.4—1.6 times the radioactivity in the blood cells. When SDS was also administered, the plasma level was 3.4—27.4 times as high as the level in the cells. Kidney was found to be the main route of excretion of antimony in rabbits. When SDS was used after AAG, about 96% of the administered dose of antimony was excreted in 72 hours, whereas only 36% was excreted in the same period if AAG was administered without SDS.

皮下注射二巯基丁二酸钠1500毫克/千克,司将小鼠一次腹腔注射锑铵的半数致死量从90—112毫克/千克提高至1300—1460毫克/千克。静脈注身锑~(124)铵予家兔後,如立刻经同一途径注射二巯基丁二酸钠,亦可降低锑铵的急性毒性。二巯基丁二酸钠的解毒机制为阻止血锑进入组织,减少锑在部分组织中的含量及增加锑自尿排泄的速度。锑主要自尿排出,用二巯基丁二酸钠後,72小时内锑由尿排出给药量的96%,而对照组动物在同时间内仅有36%由尿排出。

 
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