Modern administration must establish modern administrative decision-making mechanism whose total objective is to make scientific,democratic and lawful public decision and is a multiple-level objective system.
TERATOGENIC EFFECTS OF ROUTES OFDIFFERENT ADMINISTRATION OF 2-N, N-BIS (HYDROXYMETHYL)AMINO-1, 3, 4-THIADIAZOLE (BIS-HM-A-TDA)ON PREGNANT RATS AND DETOXICATION OF NICOTINAMIDE (NA) AND NICOTINIC ACID (NIA)
Overall the pharmacokinetic properties of both isomers were similar in rats, monkeys and humans, with β-isomer exhibiting longer elimination half-life, MRT, volume of distribution and clearance, irrespective of the route of administration.
5-FU-PT was given to rats by oral administration at a dosage of 22.5?mg kg-1.
In some organs (apart from kidneys, intestinal system, and stomach) the uptake of 99mTc-AA was not significantly affected by the administration of 99mTc with CPR or 99mTc with APAP at 120?min.
The administration of 99mTc-AA with PPA in rats caused an increase of the uptake of 99mTc-AA at 120?min in the investigated organs compared to the administration of 99mTc-AA alone.
From these data, it may be deduced that the administration of high concentration of 18-methyl norethindrone can displace ketoprofen from its secondary binding site.