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acute period
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  急性期
    RESULTS: The adhesion ability of BMSC in acute period of ALL to BMMC was lower than that of control group.
    结果 :急性期组ALLBMSC对骨髓造血细胞的粘附能力明显下降。
短句来源
    The expression of ICAM-1 on the surface of BMSC in acute period of ALL is much lower than that of control group.
    急性期组ALLBMSC表面ICAM - 1表达明显降低。
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  “acute period”译为未确定词的双语例句
    Results During the acute period, brain edema arround the injectingsite, demylinization of brain stem and non-significant pathological changes in heart, liver, lung and kidney were detected.
    结果3个月内,中枢神经系统的主要病理变化为脑干脱髓鞘变。 其它病理变化包括心肌间质灶性炎症,肝脏浊肿变性,肾小管浊肿变性甚至水样变性,但这些病理变化在3个月后处死的动物中已不存在。
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  acute period
HIV-1 infection of neonates results in an extended acute period of virus replication, frequent neurological problems and reduced survival compared to adults.
      
In frontoparietal cortex, count of viral antigen (+) neurons peaked during the acute period (27.7±6.8), dropped within the intermediate (4.8±4.0 to 1.4±1.1) and increased (7.6±4.3) at the onset of the late neurological syndrome.
      
Serotonin levels were decreased in the acute period.
      
Patients were divided into two subgroups: group 1 consisted of 29 patients with good functional outcomes from the acute period; group 2 consisted of 23 patients with poor functional outcomes.
      
Use of Transcranial Magnetic Stimulation with Measurement of Motor Evoked Potentials in the Acute Period of Hemispheric Ischemic
      
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Objective: To explore the effects of highdoserate (HDR) intracavitary irradiation on histology and epithelial DNA content of the esophagus. Methods: Fortynine rabbits were randomized into 10Gyrayirradiated, 15Gyrayirradiated and the control groups. The changes of histology and epithelial DNA content of the esophagus were observed at several time phases after the irradiation. Results: ①In the 10Gyrayirradiated group, there were mucosal and submucosal congestion and superficial ulcer. ②In the 15Gyrayirradiated...

Objective: To explore the effects of highdoserate (HDR) intracavitary irradiation on histology and epithelial DNA content of the esophagus. Methods: Fortynine rabbits were randomized into 10Gyrayirradiated, 15Gyrayirradiated and the control groups. The changes of histology and epithelial DNA content of the esophagus were observed at several time phases after the irradiation. Results: ①In the 10Gyrayirradiated group, there were mucosal and submucosal congestion and superficial ulcer. ②In the 15Gyrayirradiated group, severe mucosal injury was seen from the 7th to 14th day after irradiation. In the 6th week after irradiation, chronic injuries such as necrosis and degeneration of the epithelium and degeneration of the blood vessels were found. ③In both the two groups, no significant changes of the DNA index (DI) were seen in the esophageal mucosa after irradiation and Sphase fraction (SPF) was closely related to the histological changes of the esophagus. SPF was lower in the acute period of mucosal injury than in the recovering period. Conclusion: To induce the serious damage of the esophagus, HDR intracavitary irradiation with a dose lower than 10Gy is recommended to be used to treat esophageal carcinoma.

目的:研究高剂量率(HDR)腔内近距离辐射正常食管的组织学改变及与食管上皮细胞DNA含量变化的关系,探讨其临床价值。方法:选用家兔49只,分10Gy组、15Gy组和对照组,分别于接受照射后不同时间检查组织病理学改变及食管上皮DNA含量变化。结果:10Gy组仅有粘膜和粘膜下层充血和浅溃疡,7d炎症明显,2周即可见上皮修复表现。15Gy组在7~14d出现了严重的上皮及肌层损伤,持续6周以上,损伤后的修复均有明显的纤维增生。未发现受照射后食管上皮DNA倍性(DI)的改变,S期细胞比例(SPF)改变与组织病理学改变相一致,急性炎症期SPF减少,恢复期SPF回升并增高。结论:为保证正常食管免受过量照射,HDR近距离治疗食管癌时单次剂量应在10Gy以下。HDR辐射对正常食管上皮的DNA含量无明显改变,放射损伤及修复中上皮细胞周期中SPF变化与组织病理学改变一致。

Objective To evaluate the acute and long term toxicity effects of HSV-TK/GCV system.Methods Six rhesus monkeys received the vector producing cells (pLTKcSN/VPC)injection into the right frontallobe. After seven days, half of them were given ganciclovir through pripherial vein. At different intervals the animals were sacrificed. Histologic studies, in situ hybridization of HSV-TK sequence and PCK detection of HSV-TKgene in brain and Other organs were carried out. Results During the acute period, brain edema...

Objective To evaluate the acute and long term toxicity effects of HSV-TK/GCV system.Methods Six rhesus monkeys received the vector producing cells (pLTKcSN/VPC)injection into the right frontallobe. After seven days, half of them were given ganciclovir through pripherial vein. At different intervals the animals were sacrificed. Histologic studies, in situ hybridization of HSV-TK sequence and PCK detection of HSV-TKgene in brain and Other organs were carried out. Results During the acute period, brain edema arround the injectingsite, demylinization of brain stem and non-significant pathological changes in heart, liver, lung and kidney were detected. The in situ hybridization of HSV-TK Sequence unveiled that the life sop of the vector producing cells in monkey brain was three weeks, PCR examination of VHSV-TK gene showed negative results in all tissue specimens. Theacute pathological changes vanished three months later. Conclusions The results of our studies disclose that the toxicity effects of HSV-TK/GCV system are slight and acceptable.

目的在灵长类动物中观察单纯疱疾病毒1型胸苷激酶基因(HSV-TK)及更昔洛韦(GCV)系统的短期和长期毒副作用。方法恒河猴7只,其中1只设为正常对照,其余6只动物于右侧额叶白质内注射HSV-TK的包装细胞悬液(pLTKcSN/VPC),细胞注射后7天起,其中3只动物经外周浅静脉滴注GCV,剂量5mg/kg·d,共14天;另外4只不用药。动物在不同时间点处死,取注射针道周围的脑组织进行HSV-TK序列原位杂交,并取全身各脏器进行全面组织学检查和HSV-TK序列PCR检测。结果3个月内,中枢神经系统的主要病理变化为脑干脱髓鞘变。其它病理变化包括心肌间质灶性炎症,肝脏浊肿变性,肾小管浊肿变性甚至水样变性,但这些病理变化在3个月后处死的动物中已不存在。HSC-TK序列原位杂交结果见细胞注射后3周内有阳性细胞存在,3个月后处死的动物呈阴性改变。实验过程中动物的血液和脑脊液各项指标的动态观察未见有特异性改变。结论HSV-TK及GCV系统在用药后短期内对灵长类动物的心脏、肝脏和肾脏有一定的毒性损害作用,但是可恢复的。关键词##4脑肿瘤;;胸苷激酶基因;;更昔洛韦;;逆转录病毒

Most expers thought that gamma knife didn’t apply to treat gliomas,the main reason is that they are afraid that gliomas grow aggressively with no clear margins,that unable to be established the margin when treamed and appear the worsen symptom or new neurological deficits resulting from tumor reaction after treatment.We analyze restrospectly 46 patients whom were treated by gamma knife,and made a statistically analysis of clinical results of 43 cases,31 cases and all cases in acute period (72 hours ),three...

Most expers thought that gamma knife didn’t apply to treat gliomas,the main reason is that they are afraid that gliomas grow aggressively with no clear margins,that unable to be established the margin when treamed and appear the worsen symptom or new neurological deficits resulting from tumor reaction after treatment.We analyze restrospectly 46 patients whom were treated by gamma knife,and made a statistically analysis of clinical results of 43 cases,31 cases and all cases in acute period (72 hours ),three months, one to seventeen months respectively,and analyze imaging results of 17 cases,37cases in three months,three to seventeen respectively.The results show that gamma knife is a more effective way to treat gliomas.

⑶大多数学者认为⒙ Gam m a knife 不适合用于治疗脑胶质瘤⒙主要是担心脑胶质瘤尤其是低分化肿瘤在脑内呈浸润性生长⒙边界不清⒙治疗过程中无法确定边界⒙术后瘤体反应会导致治疗前症状的恶化或出现新的症状⒚回顾分析 46 例接受了旋转式伽玛刀治疗后的脑胶质瘤患者⒙分别对急性期⒉72h⒕43 例患者、3 个月 31 例患者和全部患者的 1~17 个月的临床随访做了统计分析⒙对 3 个月 17 例患者和 3~17 个月 37 例患者的影像学随访做了前后对比分析⒙结果认为应用旋转式伽玛刀治疗脑胶质瘤也不失为一种良好的治疗手段

 
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