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human plasma     
相关语句
  人血浆
     A DIRECT MEASUREMENT OF HUMAN PLASMA ANGIOTENSIN Ⅱ BY RADIOIMMUNOASSAY
     人血浆中血管紧张素Ⅱ放射免疫直接测定法
短句来源
     Clinical Significance of Concomitant Determinationg of ACTH and Cortisol in Human Plasma by Radio-Immuno-Assay
     人血浆ACTH和皮质醇相伴的放射免疫测定及其临床意义
短句来源
     SIMULTANEOUS DETERMINATION OF THE CONCENTRATION OF PHENYTOIN AND PHENOBARBITAL IN NORMAL HUMAN PLASMA BY HIGH-PRESSURE LIQUID CHROMATOGRAPHY
     应用高压液相色谱分析法同时微量测定人血浆中苯妥英钠和苯巴比妥的浓度
短句来源
     SPECTROFLUOROMETRIC DETERMINATION OF QUINIDINE CONCENTRATION IN HUMAN PLASMA
     荧光光谱法测定人血浆中奎尼丁浓度
短句来源
     AN IMPROVED HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC METHOD FOR DETERMINATION OF 5-FLUOROURACIL IN HUMAN PLASMA
     人血浆中5—氟脲嘧啶的高效液相色谱测定方法
短句来源
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  血浆
     A DIRECT MEASUREMENT OF HUMAN PLASMA ANGIOTENSIN Ⅱ BY RADIOIMMUNOASSAY
     人血浆中血管紧张素Ⅱ放射免疫直接测定法
短句来源
     Clinical Significance of Concomitant Determinationg of ACTH and Cortisol in Human Plasma by Radio-Immuno-Assay
     人血浆ACTH和皮质醇相伴的放射免疫测定及其临床意义
短句来源
     SIMULTANEOUS DETERMINATION OF THE CONCENTRATION OF PHENYTOIN AND PHENOBARBITAL IN NORMAL HUMAN PLASMA BY HIGH-PRESSURE LIQUID CHROMATOGRAPHY
     应用高压液相色谱分析法同时微量测定人血浆中苯妥英钠和苯巴比妥的浓度
短句来源
     PAIRED INVESTIGATION ON ZINC VALUES IN HUMAN PLASMA VERSUS SERUM
     血浆锌值与血清锌值的比对研究
短句来源
     SPECTROFLUOROMETRIC DETERMINATION OF QUINIDINE CONCENTRATION IN HUMAN PLASMA
     荧光光谱法测定人血浆中奎尼丁浓度
短句来源
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  人体血浆
     Analysis of Vitamin C Concentration in Human Plasma and Evaluation of Bioequivalence of Vitamin C Preparations
     维生素C人体血浆浓度分析与制剂生物等效性评价
短句来源
     RP-HPLC FOR DETERMINATION OF CHLORZOXAZONE IN HUMAN PLASMA
     RP-HPLC测定人体血浆中氯唑沙宗
短句来源
     RP - HPLC Determination of Gemcitabine Concentration in Human Plasma
     RP-HPLC法测定人体血浆中吉西他滨的浓度
短句来源
     Determination of tinidazole in human plasma by HPLC
     HPLC测定人体血浆中替硝唑浓度
短句来源
     A method for the determination of germanium in human plasma and urine after oral uptake of organic germanium tonic(Ge 132)is described.
     研究了口服有机锗(Ge-132)后人体血浆及尿中锗的测定方法。
短句来源
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  人血
     EXPERIMENT ON PYROGEN REMOVAL PROCESS FOR HUMAN PLASMA ALBUMIN PRODUCTION
     人血白蛋白热原去除工艺的实验
短句来源
     Determination of Adefovir Concentration in Human Plasma by HPLC
     高效液相色谱法测定人血中阿德福韦浓度
短句来源
     Study on measurement of plateletactivating factor in human plasma with reversed high performance liquid chromatography and its clinical significance
     反相高效液相色谱法测定人血中血小板活化因子方法学的研究及其临床意义
短句来源
     Study on Method for the Determination of Human Plasma HDL Biological Activity
     人血高密度脂蛋白生物活性测定方法的研究
短句来源
     The major selenium\|containing protein in human plasma is albumin or selenoprotein P (Se\|P) and in erythrocyte is hemogleobin.
     人血浆白蛋白或血浆硒蛋白P(SeP)和血红蛋白是人血硒的优势结合蛋白.
短句来源
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      human plasma
    These derivatives exhibited in vitro stability in buffers of pH 2.0 and 7.4 for 6 h and were readily hydrolyzed by human plasma esterases to liberate the parent drug.
          
    The level of glutathione in human plasma did not depend on the age and was not genetically fixed.
          
    Human Plasma trans - Sialidase Donor and Acceptor Specificity
          
    Earlier we have isolated from human plasma desialylated low density lipoproteins (dLDL) and showed that, first, dLDL induce cholesterol esters accumulation-the main process accompanying atherosclerosis development.
          
    In this study we have isolated from human plasma an enzyme transferring sialic acid residues (trans-sialidase) by affinity chromatography and studied its donor and acceptor specificity.
          
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    The direct detection of plasma angiotensin Ⅱ (AT Ⅱ) by radioimmunoassay with 0.5 ml of human blood was achieved by utilizing fine-quality antisera, ~(125)Ⅰ. AT Ⅱ of high speoifio aotivity and the double antisera separation technique.The detecting limit for competitive inhibition ourve (n =28) was 3.6 ± 1.6 pg (m. ± S. D.), and the preoision was 4.7 ±1.4% (m. ±S. D.).The C. V. in plasma measurement were 7~14% for the within assay, and 8.7~ 18 % for the between assays respectively.AT Ⅱ showed a linear increase...

    The direct detection of plasma angiotensin Ⅱ (AT Ⅱ) by radioimmunoassay with 0.5 ml of human blood was achieved by utilizing fine-quality antisera, ~(125)Ⅰ. AT Ⅱ of high speoifio aotivity and the double antisera separation technique.The detecting limit for competitive inhibition ourve (n =28) was 3.6 ± 1.6 pg (m. ± S. D.), and the preoision was 4.7 ±1.4% (m. ±S. D.).The C. V. in plasma measurement were 7~14% for the within assay, and 8.7~ 18 % for the between assays respectively.AT Ⅱ showed a linear increase concomittantly with the inorement of the plasma from 0.1 to 1.5 ml.AT Ⅱ added into the plasma could be quantitatively recovered (97~117%).There was no evidenoe of interference by the addition of eight peptide hormones, human plasma proteins, proteolytio enzymes and enzyme inhibitors.The mean concentrations of the peripheral venous plasma AT Ⅱ of normall persons on free diet were as follows: 26±10 pg/ml(n=54) while assuming a recumbent position for 1.5 hour, with a negative correlation to 24 hours urinary sodium exeretion (p<0.01); 46±22 pg/ml (n=17) after assuming an erect position for 2 hours.The plasma AT Ⅱ values were markedly elevated after provocation either with a low sodium diet or an intramuscular injection of furosemide (p<0.01).As a sensitive, speoifio, accurate and simple method for the deteotion of minute quantities of plasma AT II, this method should be useful for clinical investigations and for research on the renin-angiotensin system.

    应用优质抗血清、高比放射度~(125)Ⅰ·ATII及双抗体分离技术,建立了直接测定0.5毫升人血浆中血管紧张素Ⅱ(ATII)的放射免疫分析法。竞争抑制曲线的最小检出量3.6±1.6微微克,精密度4.74±1.4%(28次的m±S.D.)。血浆测定的变异系数为批内7~14%,批间8.7~18%。加入血浆中的ATII可定量回收(97~117%)。随待测血浆加入量增大(0.1至1.5毫升/孵育管),测得ATII量线性增加。8种肽类激素、人血浆及使用的酶抑制剂未显示出明显的干扰。正常人普通饮食时外周静脉血浆ATII浓度:卧位1.5小时以上后26±10微微克/毫升(n=54),与24小时尿钠排出量呈负相关(p<0.01);立位2小时后464±22微微克/毫升(n=17)。低钠饮食或肌肉注射速尿引起血浆中ATII显著激发(p<0.01)。本法可灵敏、精密、特异地正确度量微量ATII,操作简单,每批可测标本数较大。本法的建立有助于各领域中涉及肾素——血管紧张素系统之临床或实验研究工作。

    The binding of N-methylbenzothiazole-rifamycin (R 75-1) to normal human plasma has been studied by means of differenti al spectrophotometry method. The differential absorption spectra for the interaction of several concentrations of R 75-1 and different levels of human plasma in phosphate buffer at pH 7.0 are presented and compared to those of the rifampicin plasma. Differential spectra of R 75-1-plasma were characterized by two positive peaks (380 and500 nm) in the wavelength range of...

    The binding of N-methylbenzothiazole-rifamycin (R 75-1) to normal human plasma has been studied by means of differenti al spectrophotometry method. The differential absorption spectra for the interaction of several concentrations of R 75-1 and different levels of human plasma in phosphate buffer at pH 7.0 are presented and compared to those of the rifampicin plasma. Differential spectra of R 75-1-plasma were characterized by two positive peaks (380 and500 nm) in the wavelength range of 300 to 600 nm,while the spectra of rifampicin-plasma have no such a peak. The intensity of the differential absorption for the interaction of R 75-1 with human plasma is higher than that of rifampicin-plasma system.These results show that the differential spectra for the rifamycin derivative may be dependent on the characteristics of the C-3 substitue-nts. Binding parameters, including the nu- mber of binding sites and the binding constants were calculated for R 75-1 and plasma system at the antibiotic cocentration range of 1 to 3×10-5M, at different plasma concentrations. The binding constant for R 75-1 increased with increasing plasma concentration, whereas the number of binding sites on the plasma decreased with increasing plasma concentration. These results suggest that human plasma have different capacity and affinity sites for binding to the R 75-1.

    应用差示分光光度法研究了N-甲基苯并噻唑力复霉素(R-75-1)与正常人血浆的结合行为。获得的差示吸收谱表明R-75-1与人血浆的相互作用较甲哌力复霉素强烈。结合参数的测定结果发现,R-75-1与人血浆的结合常数随人血浆浓度的增加而增加,结合位置的数目则随人血浆浓度的增加而减少,认为人血浆对R-75-1的结合存在着不同亲和力和不同结合容量的结合位置。

    Measurement of enkephalin in human plasma has been hampered by the extremely low concentration of circulating enkephalin and its rapid degradation by proteolytic enzymes. This report describes a new radioimmunoassay method of determining fasting human plasma immuno-active Leu-enkephalin (LEK),which averages 127.9±5.4 pg/ml (m±S.E.M., n=61). The method depends on a sensitive redioimmunoassay and rapid acidification of plasma. The immunogens were first prepared by condensation of LEK with Thyro-globulin....

    Measurement of enkephalin in human plasma has been hampered by the extremely low concentration of circulating enkephalin and its rapid degradation by proteolytic enzymes. This report describes a new radioimmunoassay method of determining fasting human plasma immuno-active Leu-enkephalin (LEK),which averages 127.9±5.4 pg/ml (m±S.E.M., n=61). The method depends on a sensitive redioimmunoassay and rapid acidification of plasma. The immunogens were first prepared by condensation of LEK with Thyro-globulin. Rabbits were then immunized by multiple intradermal inoculation. Specific antiserum (ALS) was thus obtained with the working dilution of 1:20,000. No significant interference with β-endorphin, 8 peptide hormones, morphine and naloxone were found. The cross reaction rate of MIK vs. ALS was 2.17%. This radioimmunoassay has proved very sensitive and can detect as low as 5 pg LEK and is suitable for LEK measurement in human plasma.Several tests for validating the methodology have been processed. The authors observed that plasma LEK increased during insulin-induced hypoglycemia; and a rise of LEK was noticed in human pheoehromoeytomas, suggesting that plasma enkephalin might be derived from the adreno-medulla.The role of plasma enkephalin and its significance in normal and abnormal physiological states remains to be elucidated. However, the present method will be likely to permit such dynamic studies.

    血浆中脑啡肽(EK)含量极微且迅速酶解,测定很困难。本文报告了人血浆LEK样物质放射免疫测定值为127.9+5.4pg/ml(m±S. E. M,n=61)。作者用TG-ECDI-LEK背部皮内多点法免疫家兔,得高灵敏度、高特异性的抗血清;迅速酸化血浆防止EK酶介;XAD-2树脂吸附EK和水合甲醇洗脱提取。本法已通过多种方法学考验。作者观察到胰岛素低血糖试验和踏车运动激发血LEK升高;嗜铬细胞瘤患者血LEK增高,提示LEK可能来源于肾上腺髓质。本法为研究循环中EK变化提供了条件。

     
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