GEOGRAPHICAL DIFFERENTIATION OF SELENIUM CONTENT IN HAIR FROM CHILDREN AND YOUNGSTERS IN CHINA——A discussion about relationshipbetween selenium deficiency and geographical epidemiology of the Keshan disease
In this study, an assessment system of chemicals toxicity to hair in vitro was established by means of cultivating hair follicle of dorsal skin and vibrissa of SD rats in vitro in Williams'E media without serum.
Using the method of feeding the feed enriched sulfydryl by adding peas,lentils and hydrolysate of hair,respectively,the protective effects of sulfydryl in the mice fed the feed with arsenic content of 80 mg/kg were observed.
Five characteristics (hair forms, nasal profile, nostril forms, mongoloid fold and upper eyelid fold) were respectively investigated in six nationalities, including the Buyi, Miao, Shui, Maonan, Dong, and Han nationalities in Southern Guizhou, China.
The results indicated that: (1) for hair forms and nasal profile, the frequency of the dominant gene was lower than that of their recessive gene, but the opposite was true for nostril forms.
(2) Among different nationalities, the difference of gene frequency of the mongoloid fold, nasal profile, hair forms and upper eyelid fold was quite significant, which was followed by that of nostril forms.
The focus of this study is to determine the relationship between selenium (Se) concentrations in child hair and the distribution of Kashin-Beck disease (KBD) in Tibet.
The results obtained from investigations in the field and laboratory showed that selenium deficiency plays an important role in the causation of Keshan disease. This conclusion is based on: ( 1 ) Oral administration of sodium selenite was highly effective in the prevention of Keshan disease. In Mianning county of Sichuan province, the incidence rate of Keshan disease in the selenium treated children were 2.2% and 1.0% in 1974 and 1975 respectively, while those of the control group were 13.5% and 9.5%, both ...
Endemic selenosis in animals was believed to have been reported first in 1295 by Marco Polo in Western China,but conclusive evidence had not yet been ob tained in that region. An etiological investigation on this disease in human being was made in Enshi Region,Hubei Province.Results showed that selenium contents in blood and hair of residents in endemic area were far higher than those in nearby nonaffected area, endemic area of Keshan disease and Beijing. Stony coal was proved to be the source of sele...
The appearance of selenium poisoning in Enshi County was basically due to the exceedingly high selenium contents of stony coal distributed in that area. Weathering process would bring part of the coal selenium to the soil and thus make its way to crops and vegetables. The monotonus peasants' diclary pattern helped to render selenium finding its way into human body. Drought would concentrate the soil solution and increase the selenium contents of plants. Due to the failure of rice, people had to take more ve...