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hematological malignancies
相关语句
  恶性血液病
     Expression of 4-1BBL molecule in the cell lines of human hematological malignancies
     4-1BBL分子在人恶性血液病细胞系的表达
短句来源
     Mean MTase activity in 15 cases with acute leukemia was (9.1±4.6)%,4 fold higher than that in 11 cases with no hematological malignancies which was ( 2.1± 1.6)% ( P <0.05);
     15例急性白血病MTase活性平均值为(9.1±4.6)%,较11例非恶性血液病对照组[平均(2.1±1.6)%]明显升高。
短句来源
     Methods Sixteen patients with hematological malignancies were treated by allo PBSCT, started from march 1997. Five of them were ALL (CR1 4,CR2 1), 2 ANLL (CR1), 8 CML(CP 5,AP 3),and one NHL(PR).
     方法 用异基因外周血干细胞移植治疗恶性血液病16 例,其中急性淋巴细胞白血病5 例(CR1 4 例,CR2 1 例) , 急性非淋巴细胞白血病2 例(CR1) ,慢性粒细胞白血病8 例(CP5 例,AP3 例) ,非霍奇金淋巴瘤1 例(PR) 。
短句来源
     The count increasing valuation after PC transfusion is (29.44±11.07)×10 9/L in solid tumor chemotherapy; and (17.32±11.33)×10 9/L in hematological malignancies, there are significant difference between them ( P <0.05). Clinical hemostasis rates 3 days after the transfusions are 79%(89/113).
     实体瘤组输血小板前后差值(29.44±11.07)×109/L较恶性血液病组(17.32±11.33)×109/L高(P<0.05),治疗3天后临床出血改善率79%。
短句来源
     A study on the relationship between serum level Tpo and platelet count in patients with hematological malignancies
     恶性血液病患者血清Tpo水平与血小板关系的研究
短句来源
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  血液肿瘤
     Methods EBV infection in hematological malignancies 38 cases was detected by PCR.
     方法  应用PCR法检测 38例血液肿瘤性疾病患儿骨髓细胞EBV -DNA。
短句来源
     The Effect of rhG-CSF on Neutrophil Function in Patients with Hematological Malignancies During Chemotherapy
     rhG-CSF对血液肿瘤病人化疗后中性粒细胞功能的影响
短句来源
     Methylcillin resistant coagulase negative staphylococcus (MRCNS) was the most prevalent Gram (+) bacteria in the complicated infection patients with hematological malignancies, which accounted for 88.5%.
     耐甲氧西林凝固酶阴性葡萄球菌为血液肿瘤患者最易感染的革兰阳性菌 ,达 88.5 %。
短句来源
     Objective To study the effect of recombinant human granulocyte colony-stimulating factor(rhG-CSF) on neutrophil function in patients with hematological malignancies receiving chemotherapy.
     目的研究血液肿瘤病人化疗后应用重组粒细胞集落刺激因子 (rhG -CSF)对中性粒细胞功能的影响。
短句来源
     EBV-DNA determination and its clinical significance in hematological malignancies
     EBV-DNA检测在血液肿瘤性疾病中的应用价值
短句来源
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  血液系统恶性肿瘤
     Research Advance on SDF-1/CXCR4 Axis Associated with Hematological Malignancies ——Review
     SDF-1/CXCR4与血液系统恶性肿瘤的关系研究进展
短句来源
     Relationship between nitration and oxidation related enzymes iNOS,COX-2 and hematological malignancies
     硝基化和氧化相关酶类iNOS和COX-2与血液系统恶性肿瘤
短句来源
     In recent years increased angiogenesis has been reported in the bone marrow of patients with hematological malignancies, such as acute myeloid leukemia (AML) , acute lymphocytic leukemia (ALL) , multiple myeloma (MM). . .
     最近发现血液系统恶性肿瘤中也存在血管新生现象,如急性非淋巴细胞性白血病(Acute myeloid leukemia,AML)、急性淋巴细胞性白血病(Acute lymphocytic leukemia,ALL)、多发性骨髓瘤(Multiple myeloma,MM)等。
短句来源
     The selective inhibitors of NOS,COX,or the both may provide a new approach for the treatment of hematological malignancies.
     针对 NOS、COX或两者的选择性抑制剂为血液系统恶性肿瘤的治疗提供了新的线索。
短句来源
     Methods Thirty-five patients with various hematological malignancies undergoing allo-HSCT were as- sessed. Of them,19 patients with HLA-matched sibling donors (group A) were conditioned with modified BU/CY regimen,16 with HLA-mismatched family members or HLA-matched unreleated donors (group B) were conditioned with modified BU/CY+ATG regimen.
     方法 35例血液系统恶性肿瘤患者中,19例配型全合的同胞间移植者(A 组)应用改良 BU/CY 方案,16例配型不合或非血缘移植者(B 组)应用改良 BU/CY+ATG 方案。
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  “hematological malignancies”译为未确定词的双语例句
     Mcl-1 and hematological malignancies
     Mcl-1与血液恶性肿瘤
短句来源
     JAK2V617F Point Mutation in Hematological Malignancies
     慢性骨髓增生性疾病JAK2基因V617F点突变研究
短句来源
     In 17 patients with proven or probable invasive aspergillosis:6patients with bone marrow(35.29%),3 patients with liver transplant(17.65%),4 patients withchronic lung infection(23.52%),2 patients with hematological malignancies (11.76%).
     结果 在 17 例确诊和高度怀疑 IA 的患者中骨髓移植的患者 6 例占 35.29%、肝脏移植的患者 3 例占 17.65%、慢性肺部感染的患者 4 例占 23.52%、白血病的患者 2 例占 11.76%;
短句来源
     and cyclophosphamide 30 mg/(kg·d),-3d~-2d, was used for allogeneic stem cell transplantation in 14 cases with hematological malignancies.
     环磷酰胺30mg/(kg·d),静滴,鄄3d~鄄2d。
短句来源
     Methods: The percentage of CD4+CD25+ Tregs of peripherial blood in CD4+ T cells in fifty patients with hematological malignancies were detected by flow cytometry in the course of Allo-PBSCT on pretransplantation,during transplantation,+day 30,+day 60,+day 90,+day 180,+day 360 respectively in order to observe the dynamic changes.
     方法:采用流式细胞术动态监测50例血液病恶性肿瘤患者Allo-PBSCT过程中,在移植前、植入时、植入后+30d、+60d、+120d、+360d外周血CD4+CD25+Tregs在CD4+T细胞中的百分含量。
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  hematological malignancies
Emerging evidence suggests that angiogenesis may play an important role in hematological malignancies, such as leukemia.
      
aeruginosa was more frequently isolated from patients with hematological malignancies and MRSA with solid tumors.
      
Endotoxemia in febrile patients with hematological malignancies.
      
The relation between gram-negative bacteremia, endotoxemia and cytokinemia in patients with hematological malignancies was studied.
      
Serum endotoxin and cytokines (tumor necrosis factor-α, interleukin-1 receptor antagonist, interferon-γ, interleukin-6 and interleukin-10) were determined in 24 patients with hematological malignancies.
      
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Measurements of ADA activity might behelpful in the diagnosis of a wide varietyof hematological malignancies and immuno-deficiency disease. To establish thenormal value of ADA activity in theChinese will be of great importance, butno such data have ever been reported. This paper reports a study of normalvalue of ADA activity by ammonia gas-sensing electrode method for 329 healthysubjects in Chengdu, Sichuan aged from 0 to74,all measures were taken under random-ized condition. Statistical analysis wasmade...

Measurements of ADA activity might behelpful in the diagnosis of a wide varietyof hematological malignancies and immuno-deficiency disease. To establish thenormal value of ADA activity in theChinese will be of great importance, butno such data have ever been reported. This paper reports a study of normalvalue of ADA activity by ammonia gas-sensing electrode method for 329 healthysubjects in Chengdu, Sichuan aged from 0 to74,all measures were taken under random-ized condition. Statistical analysis wasmade on different age groups.It was foundthat the ADA activity in whole bloodranges from 10.00 to 39.81 units. The upper limit of ADA activity in thechildren group at 95% level is 46.46 unitsand the lower is 9.89 units; the upperlimit of the adult group at the same levelis 42.98 units and the lower is 8.81 unitson the basis of statistics in percentage.TheADA activity of adult is lower than thatof the children group (P<0.01).

本文报道了用氨气敏电极法测定329例正常人血腺苷脱氨酶活性,大多数人在10. 00~39.81单位之间;儿童与成年人存在显著性差异(P<0.01),儿童组M±SD=26.58±10.08单位,成人组M±SD=20.01±9.36单位。儿童正常值95%上限为46.46单位,下限为9.89单位;成人正常值95%上限为42.98单位,下限为8.81单位。

The therapeutic effect of ceftizoxime (CZX) in 24 patients (M14, F10, age 46±16yr) with hematological malignencies complicated by severe infections is reported. The daily dose of CZX was 4-6 g iv with an average total dosage of 41 ± 16g. Excellent response was noted in 38% and fair in 25%. The total response rate was 62%. CZX was effective for both gram positive and gram negative bacterial infection, but was of no use in all 3 cases of Pseudomonas aeruginosa infection. It was also found that the response of...

The therapeutic effect of ceftizoxime (CZX) in 24 patients (M14, F10, age 46±16yr) with hematological malignencies complicated by severe infections is reported. The daily dose of CZX was 4-6 g iv with an average total dosage of 41 ± 16g. Excellent response was noted in 38% and fair in 25%. The total response rate was 62%. CZX was effective for both gram positive and gram negative bacterial infection, but was of no use in all 3 cases of Pseudomonas aeruginosa infection. It was also found that the response of treatment was better for patients with neutrophil count above 1.0xl09/L than those below this level. Adverse effect was slight. Yellowish color vision was noted in* a patient, which disappeared after withdrawal of the drug. No fever or drug rash was noticed. It is suggested that CZX is a safe and useful broad-spectrum antibiotics for the treatment of severe infection complicating hematological malignancies.

本文报道头孢唑肟(ceftizoxime)治疗24例(男14例,女10例,平均年龄46±16yr)恶性血液病并发重症感染。剂量为4-6g/d,iv,总剂量平均为41±16g,结果显效38%,有效25%;总有效率62%,头孢唑肟对革兰阳性菌和阴性菌均有效,但对绿脓杆菌感染无效。患者中性粒细胞绝对计数高于1.0×10~9/L的有效率高。本药副作用轻微,是一种安全,有效的广谐抗生素。

Chronic myeloid leukemia (CML) is a hematological malignancy characterized by a reciprocal translocation t (9;22), that results in the fused bcr/abl gene and the chimeric 8.5kb transcript. The transformative activity of the bcr/abl gene has been confirmed by introducing bcr/abl constructs in mice. Furthermore, leukemic colony formation is selectively suppressed when CML blast cells are exposed to synthetic oligodeoxynucleotides complementary to bcr/abl gene junction region. We amplified the bcr/abl gene...

Chronic myeloid leukemia (CML) is a hematological malignancy characterized by a reciprocal translocation t (9;22), that results in the fused bcr/abl gene and the chimeric 8.5kb transcript. The transformative activity of the bcr/abl gene has been confirmed by introducing bcr/abl constructs in mice. Furthermore, leukemic colony formation is selectively suppressed when CML blast cells are exposed to synthetic oligodeoxynucleotides complementary to bcr/abl gene junction region. We amplified the bcr/abl gene junction region from K562 cell RNA using a pair of synthetic primers by RT-PCR technique and inserted it into pGEM-4Z plasmid. The PCR product was a 0.3 kb DNA fragment. Restriction analyses of the recombinant plasmids suggested that we had got the clones of the target sequence. Results from sequencing analyses supported that the plasmid, pB3A2, contained a 0.3kb fragment homologous to the b3a2-type junction region cDNA of bcr/abl gene. The plasmid pB3A2 may provide a good source of probes and antisense plasmids in further studies on selective killing of CML cells.

利用分子生物学方法,我们将K562细胞林bcr/abl mRNA 0.3kb的接合区cDNA片段用聚合酶链反应扩增并插入到质粒pGEM-4-Z载体中。经限制酶切分析和荧光标记M13引物法DNA序列测定,证实重组质粒pB3A2中有0.3kb的插入片段与K562 mRNA接合区序列完全一致。我们分离到的接合区DNA可用于bcr/abl基因的检测及其反义核酸抑制的研究。

 
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