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combination assay
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  联合检测
     Diagnosis Value of Combination Assay of Three Tumour Markers,C_(A125)、C_(A153)and C_(A242) in Lung Cancer
     血清C_(A125)、C_(A153)、C_(A242)三种肿瘤标志物联合检测对肺癌诊断的价值
短句来源
     If combination assay of 4 markers AFP, GGTⅡ, SF and α 1AT was taken, the diagnostic rate was 95.4% in PHC.
     若将AFP、GGTⅡ、SF、α1AT 4项标志物联合检测 ,总阳性率可达 95 .4 %。
短句来源
     In 21 cases with PHC whose AFP were less than 400μg/L, the positive rates of GPDA-F and AFU were 71.4% and 47.6%, and reached 85.7% with combination assay of AFU and GPDA-F.
     在AFP <40 0mg/L的 2 1例肝癌患者中 ,单项GPDA -F和AFU的阳性率分别为 71.4%与 47.6% ,联合检测的阳性率达 85 .7%。
短句来源
     Conclusions Serum tumor markers such as CA153、CA125、CEA、FER have clinic value to predicting bone metastases of breast cancer. Combination assay of CA153、CA125、CEA、FER could increase the accuracy of predicting bone metastases.
     结论CA153、CA125、CEA、FER具有预测乳腺癌骨转移的临床价值,联合检测CA153、CA125、CEA、FER能提高其预测乳腺癌骨转移的准确性。
短句来源
     The combination assay of urinary Ψ and serun AFP could further raise the detection rate of PHC up to 88.1%.
     尿Ψ与血清AFP之间无相关性(P>0.5),尿Ψ与血清AFP联合检测能进一步提高PHC诊断阳性格出率至88.1%。
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  “combination assay”译为未确定词的双语例句
     When many tumor markers were all positive in above the combination assay,the specificity could be reached to 100% but the positive rate lowered to 64 71%.
     若上述联检中多项标记物均阳性,对癌性心包液诊断的特异性可达100% ,但敏感性降为64-71% 。
短句来源
     Results Of six McAbs which were obtained from and specific to HIV 1 p24 antigen by WB. The Sandwich EIA kit was constructed with p24 1 and 10 for coating and p24 6 for labelling aspectly by cross combination assay.
     交叉组合试验确定单抗p24-1和10用于固相,p24-6用于标记辣根过氧化物酶。 试剂盒临界值为0.15+阴性对照值;
短句来源
     In multivariate analysis using Cox regression model,combination assay of nm23-H1 and SleX expression (emerged) as independent prognostic factors.
     综合分析 nm2 3- H1表达和 Sle X表达与预后的关系显示 ,Sle X阳性表达合并 nm2 3- H1低表达的患者预后最差。
短句来源
     It was significantly lower than that of CA50+CEA. The specificity of pleural CEA in combination with CA50,assays was increased to 79%. The positive rate of combination assay of 5 markers was significantly higher than single marker (P<0 05).
     CEA +CA50联检特异性为 95 % ,灵敏度为 79% ,较CA50、TSA、CEA、SF、IL - 8、CEA单项检查增高 (P <0 0 5)。
短句来源
     Objective To study the value of combination assay of multiplex RT PCR and karyotypic analysis in the diagnosis and classification of childhood acute lymphoblastic leukemia(ALL).
     目的 研究多重逆转录 聚合酶链反应 (RT PCR)技术联合染色体核型分析在急性淋巴细胞白血病 (ALL)诊断分型中的价值。
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  相似匹配句对
     With combination of M. D.
     D.
短句来源
     Selection and Combination
     选择与组合
短句来源
     The Expression of Human cTnI and cTnC in E.coli and Their Combination Assay
     人心肌肌钙蛋白I和C亚基的基因工程表达及两者的结合实验
短句来源
     Conclusions Combination of bile DLBA and CEA assay is helpful to the diagnosis of BDC.
     结论 胆汁蔓陀罗凝集素结合活力联合癌胚抗原测定有助于胆管癌的诊断。
短句来源
     The method of assay is accurate.
     测定方法准确,回收率高。
短句来源
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  combination assay
The combination assay was also impressive in early detection of colorectal cancer (Dukes' A, 52%; Dukes' B, 57.1%).
      
Thus, combination assay with PIVKA-II and AFP seems useful for increasing the accuracy of laboratory diagnosis of HCC.
      
When a combination assay with both genes was used, molecular abnormalities were detected in 80.0% of cases, including 3 in which p53 alone was positive.
      
These results sugest the usefulness of a combination assay of Hb and Tf as a fecal occult blood test.
      
Qualitative analysis of the values obtained by the combination assay of Hb and Tf with a cutoff value of 0.200 revealed positive rates of 41/51 in the colon cancer gorup, 33/95 in the colon polyp group, and 4/110 in the control group.
      
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In order to evaluate combined serum tumor enzyme determinations in the diagnosis of hepatocellular carcinoma (HCC), four tumor markers including gamma-glutamyl tran- speptidase isoenzyme (r-GT-II), alkaline phosphatese isoenzyme (ALP-I), the ratio of the two aldolase activities, fructose-1, 6-diphosphoaldolase and fructose-1-phosphoaldo-lase (FDP/FIP) and a-L-fucosidase (AFU) were concomitantly determined in 59 patients with HCC, 97 patients with various liver diseases and gastrointestinal tumors. The results...

In order to evaluate combined serum tumor enzyme determinations in the diagnosis of hepatocellular carcinoma (HCC), four tumor markers including gamma-glutamyl tran- speptidase isoenzyme (r-GT-II), alkaline phosphatese isoenzyme (ALP-I), the ratio of the two aldolase activities, fructose-1, 6-diphosphoaldolase and fructose-1-phosphoaldo-lase (FDP/FIP) and a-L-fucosidase (AFU) were concomitantly determined in 59 patients with HCC, 97 patients with various liver diseases and gastrointestinal tumors. The results revealed that: (l)r-GT-II, ALP-I, FDP/FIP and AFU level were increased significantly in HCC (P<0.01); (2) The diagnostic sensitivity and specificity of these markers in HCC were r-GT-II(79.7%)>AFU(78.8%)>FDP/FIP(61%)>ALP-I(16.95%) and ALP-I(100%) >r-GT-II(92.l%)>AFU(90.9%)>FDP/FIP (88.8%), respectively; (3) The diagnostic positivity of combination assay was 80.0% in low or negative AFP producing HCC, while 95.7% in those with elevated AFP. Our data suggested that the combination assay of serum tumor enzyme markers was valuable in the diagnosis of HCC, especially in low or negative AFP HCC patients

本文对59例原发性肝癌(HCC)和97例其他肝病及消化道肿瘤患者进行了血清肿瘤酶标志物的联合测定。结果显示HCC组的r-谷氨酰转肽酶同工酶、碱性磷酸酶同工酶、醛缩酶同工酶及血清α-L-岩藻糖苷酶的活力均较正常组显著增高(P<0.01),四种酶联合检测对AFP(一)HCC的诊断阳性率为80%,与AFP联合检测对HCC总的诊断检出率达95.7%

The serum levels of eight tumor markers were assayed in 70 patients with lung cancer(LC), 24 patients with pulmonary tuberculo- sis,20 patients with cot pulmonale, and 61 healthy adults by biochemical, immunochemical and radioimmunoassay methods.The resultant data underwent a stepwise discriminant analysis (SDA)by computer in order to as- sess the value of this method in diag- nosing patients with(LC),indicating that in LC,the levels of LSA,α_1- AG,α_1-AT,β_2-MG,SF,and IgM CIC rose markedly,and the optical densi-...

The serum levels of eight tumor markers were assayed in 70 patients with lung cancer(LC), 24 patients with pulmonary tuberculo- sis,20 patients with cot pulmonale, and 61 healthy adults by biochemical, immunochemical and radioimmunoassay methods.The resultant data underwent a stepwise discriminant analysis (SDA)by computer in order to as- sess the value of this method in diag- nosing patients with(LC),indicating that in LC,the levels of LSA,α_1- AG,α_1-AT,β_2-MG,SF,and IgM CIC rose markedly,and the optical densi- ty of EA increased.Levels of α_1-AT, β_2-MG,SF and Igm CIC rose in pati- ents with pulmonary tuberculosis;le- vels of α_1-AT,β_2-MG and SF rose in cor pulmonale.After chemical and operative therapy for LC,the levels of LSA declined significantly.The level of IgM CIC in oat cell LC was significantly higher than that in squa- mous cell LC.The category of CIC in LC was mainly IgM CIC.Results of SDA and comprehensive analysis sug- gested that the combination assay of serum EA,LSA,α_1-AT and SF is of adjuvant value in diagnosis of LC.

用生物化学、免疫化学和放射免疫方法,对70例肺癌、24例肺结核、20例肺心病患者及61名正常人进行了8项血清肿瘤标记物检测;并利用电子计算机对检测结果进行了逐步判别分析,探讨各肿瘤标记物在肺癌辅助诊断方面的意义。结果,肺癌 LSA、α_1-AG、α_1-AT、β_2-MG、SF 和 IgMCIC 水平升高,EA 光密度增加;肺结核α_1-AT、β_2-MG、SF、IgG 和 IgMCIC 水平也升高;肺心病α_1-AT、β_2-MG 及 SF 水平升高。肺癌手术和化学治疗后 LSA 降低。未分化小细胞肺癌 IgMCIC 水平高于肺鳞癌。肺癌 CIC 以 IgMCIC 为主。逐步判别分析结合综合判断分析后的数据提示,联合检测 EA、LSA、α_1-AT 及 SF 对肺癌的辅助诊断价值较大。

By means of high-performance liquid chromatography, the urinary concentration of pseudouridine(Ψ) was determined in 42 patients of primary hepatocellular carcinoma (PHC), 65 various hepatic disease, 11 gastrointestinal cancer and 40 healthy controls. The mean urinary Ψ concentration was significantly higher in the patients with PHC than those with hepatitis, liver cirrhosis, hepatic benign tumour and healthy controls,(P<0.01), but no statistical difference was found between the patients with PHC and those with...

By means of high-performance liquid chromatography, the urinary concentration of pseudouridine(Ψ) was determined in 42 patients of primary hepatocellular carcinoma (PHC), 65 various hepatic disease, 11 gastrointestinal cancer and 40 healthy controls. The mean urinary Ψ concentration was significantly higher in the patients with PHC than those with hepatitis, liver cirrhosis, hepatic benign tumour and healthy controls,(P<0.01), but no statistical difference was found between the patients with PHC and those with metastatic liver cancer, gastrointestinal cancer(P>0.05). UrinaryΨ level was elevated above the mean value plus 2SD of the healthy controls (4.7nmol/μmol creatinine) in 27 (64.3%) of 42 PHC patients, including 3 of 5(60%) small PHC patients. The results revealed that diagnostic sensitivity and specificity of urinary Ψ for PHC were 64.3% and 85.5% respectively. No correlation could be found between urinary Ψ concentration and serum AFP level (P>0.5). The diagnostic positivity was 61.6% in AFP(一) PHC patients. The combination assay of urinary Ψ and serun AFP could further raise the detection rate of PHC up to 88.1%. The results suggest that urinary Ψ can be regarded as an useful biochemical marker in the diagnosis and monitoring PHC, particularly in combination with serum AFP to increase the detection rate in PHC.

应用高效液相色谱法测定了42例原发性肝癌(PHC)、65例其它各种肝病、11例消化道恶性肿瘤和40例正常对照者的尿液假尿嘧啶核苷(假尿苷,Ψ),PHC组的尿Ψ浓度(7.0±4.2nmol/μmol肌酐)明显高于正常对照组(3.2±0.7nmol/μmol肌酐)、肝炎组(3.3±0.7nmol/μmol肌酐)、肝硬化组(3.0±1.1nmol/μmol肌酐)及肝良性占位病变组(3.0±0.8nmol/μmol肌酐,P<0.01);而与转移性肝癌组(5.8±3.6nmol/μmol肌酐)和消化道恶性肿瘤组(5.0±2.4nmol/μmol肌酐)无显著性差异(P>0.05)。在42例PHC中27例(64.3%)超过正常对照者尿Ψ浓度X±2S(4.7nmol/μmol肌酐),其中5例小肝癌有3例(60%)尿Ψ阳性。尿Ψ对PHC的诊断敏感性和特异性分别为64.3%和85.5%,对AFP阴性PHC的诊断阳性率为61.5%。尿Ψ与血清AFP之间无相关性(P>0.5),尿Ψ与血清AFP联合检测能进一步提高PHC诊断阳性格出率至88.1%。经手术切除或肝动脉插管化疗等治疗有效的7例PHC患者尿Ψ值均降低。结果显示尿Ψ作为一?

 
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