And calf aortic, pulmonaryartery endothelial cells were cultured for studying the effects of vascularheterogeneity on the changes of vessel tension promoted by pH0.
Vessel endothelium and its biology activty substance(EDRF and ET)play important roles in regulating vessel tension. They have close relation with hypertension and AS cardiovascular disease.
The balance between EDRF and EDCF keeps the blood vessel tension in normal, otherwise endothelium dysfunction will occur leading to cardiovascular diseases.
Methods Resistancy pulmonary arteries (0.3 - 0.6mm in diameter) from rats were mounted in a vessel myograph and vessel tension was recorded. The effects of 10,20,40,80,150,200, 250mgl/ml of diatrizoate,ioxaglate, iopromide, iotrolan and their mannitol osmolar control were studied.
DiscussionThese results indicate that TFE prevents the rise of blood pressure not onlyat the prehypertensive stage but also after the development of hypertension andthat this effect of TFE can decrease ET and increase NO, NOS in serum, andblock the calcium channel in order to adjust the blood vessel tension andperipheral resistance.
CONCLUSION: E 4031, sotalol and glibenclamide showed no effect on blood vessel tension at the normal range of concentration and K + channel blockers may have different selectivity for heart and blood vessels.
Methods The blood vessel tension responses to drug were measured by rabbit basilaris arteria rings (RBAR) endothelium being removed and intact endothelium in vitro.
Conclusion ARDS rats showed a lastecl increase of CO level in pulmonary blood circulation,suggesting CO/HO system might play a more important role in modulation of blood vessel tension than NO might do in pathogenesis of ARDS.
However, both anaesthetics caused a significant (P ≤ 0.05) decrease in vessel tension when compared to controls.
Hepatic portal vein rings were exposed to 1 × 10-7?M adrenaline in the presence or absence of either AQUI-STM or MS222 and changes in vessel tension measured.
Vessel tension was recorded on a Grass polygraph model 7b.
This did not appear to be dose dependent because further increases in NaHS concentration did not affect vessel tension.
Figure 10 shows the effect of the adenylate cyclase-activator forskolin on isolated pulmonary arterial vessel tension.
Using a radioimmunoassay,we studied PGI_2 and TXA_2 metabolism in the vascular walls of rabbit in different areas.The production of PGI_2 in basilar arteries and veins was significantly higher than in external iliac arteries and veins,renal arteries and veins, abdominal aorta and vein cava inferior. But there was no significant difference in the production of TXA_2 in all these vascular walls.It seems that PGI_2 plays a more important role in the maintenance of normal cerebral vessel tension and blood...
Using a radioimmunoassay,we studied PGI_2 and TXA_2 metabolism in the vascular walls of rabbit in different areas.The production of PGI_2 in basilar arteries and veins was significantly higher than in external iliac arteries and veins,renal arteries and veins, abdominal aorta and vein cava inferior. But there was no significant difference in the production of TXA_2 in all these vascular walls.It seems that PGI_2 plays a more important role in the maintenance of normal cerebral vessel tension and blood flow volume.
Lung compliance (Cmpl),peak pressure of airway (Peak),arterial CO_2 tension (PaCO_2),final respiratory CO_2 tension (PETCO_2)and diastolic blood pressure(DBP),heart rate (HR),product of heart rate and systolic blood pressure (RPP)were observed in 30 patients before gas abdominal and 10 minutes,20 minutes and 30 minutes after gas abdominal during laparoscopic cholecystectomy.After the gas abdominal,Cmpl was reduced (P<0.01),Peak,PaCO_2 and PETCO_2 levels increased (P<0.01),and DBP,HR and RPP levels...
Lung compliance (Cmpl),peak pressure of airway (Peak),arterial CO_2 tension (PaCO_2),final respiratory CO_2 tension (PETCO_2)and diastolic blood pressure(DBP),heart rate (HR),product of heart rate and systolic blood pressure (RPP)were observed in 30 patients before gas abdominal and 10 minutes,20 minutes and 30 minutes after gas abdominal during laparoscopic cholecystectomy.After the gas abdominal,Cmpl was reduced (P<0.01),Peak,PaCO_2 and PETCO_2 levels increased (P<0.01),and DBP,HR and RPP levels increased (P<0.05,P<0.01).Lung compliance was reduced and pulmonary ventilation was affected by the abdominal.CO_2 accumulated in the body,and blood vessel tension and the amount of oxygen consumed by the heart cells were increased.This indicates that gas abdominal could affect pulmonary ventilation and circulation.So respiration and circulation must be guarded during anesthesia period.
AIM: To study the effects and mechanisms of different potassium channel blockers on rat vascular smooth muscle. METHODS: Isometric tension recording of aorta strip. RESULTS: The EC 50 values of BaCl 2, 4 aminopyridine(4 AP), cesium chloride(CsCl) and tetraethylammonium(TEA) to increase tension of rat aorta strips were (0 09±0 08) mmol·L -1 ,(6 43±1 75) mmol·L -1 ,(7 6±1 92) mmol·L -1 and (11 5±3 09) mmol·L -1 , respectively. 1,4 piperidine(E 4031), sotalol and glibenclamide...
AIM: To study the effects and mechanisms of different potassium channel blockers on rat vascular smooth muscle. METHODS: Isometric tension recording of aorta strip. RESULTS: The EC 50 values of BaCl 2, 4 aminopyridine(4 AP), cesium chloride(CsCl) and tetraethylammonium(TEA) to increase tension of rat aorta strips were (0 09±0 08) mmol·L -1 ,(6 43±1 75) mmol·L -1 ,(7 6±1 92) mmol·L -1 and (11 5±3 09) mmol·L -1 , respectively. 1,4 piperidine(E 4031), sotalol and glibenclamide did not show any influence on the aorta strip tension. On the other hand, our study demonstrated that E 4031, sotalol and 4 AP can inhibit NE induced contraction in a dose dependent manner. CONCLUSION: E 4031, sotalol and glibenclamide showed no effect on blood vessel tension at the normal range of concentration and K + channel blockers may have different selectivity for heart and blood vessels.
vessel tension
血管张力
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