助手标题  
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
   genes p 53 的翻译结果: 查询用时:0.186秒
图标索引 在分类学科中查询
所有学科
肿瘤学
妇产科学
口腔科学
基础医学
眼科与耳鼻咽喉科
预防医学与卫生学
更多类别查询

图标索引 历史查询
 

genes p
相关语句
  基因p53
     Study of Apoptosis and Expression of Apoptotic Related Genes P53,bcl-2,C-myc in Oral Lichen Planus
     口腔扁平苔藓患者细胞凋亡及凋亡相关基因p53、bcl-2、C-myc的表达
短句来源
     The differences in genetic regulation between SCLC and NSCLC——The oncogenetic significance of the different expressions of apoptotic genes p53 and Bcl-2
     SCLC与NSCLC基因调控的差异——凋亡调控基因p53、Bcl-2表达的差异及意义
短句来源
     Objective: To study the effects of apoptosis and expression of apoptotic related genes P53@ bcl - 2@ C - myc on prognosis of oral lichen planus(OLP).
     目的:研究细胞凋亡及凋亡相关基因P53、bcl-2、C-myc的表达对口腔扁平苔藓(OLP)预后的影响。
短句来源
     EXPRESSION OF APOPTOSIS RELATED GENES P53 BCL-2 IN MAMMARY ATYPICAL DUCTAL HYPERPLASIA
     凋亡相关基因p53、bcl-2在乳腺导管非典型增生中表达的研究
短句来源
     Expression of Apoptosis Correlated Genes P53, Bcl-2 and Bax Oncoproteins and Its Significance in Laryngeal Squamous Cell Carcinoma
     凋亡相关基因P53、Bcl-2和Bax蛋白在喉鳞癌癌变过程中的表达及其临床病理意义
短句来源
更多       
  p53基因
     with this background,we attempt to investigate the effects of apoptosis and its regulating genes p53,bcl-2 in Bowen’s disease and bowenoid papulosis of the skin and genitala .
     P53基因位于17号染色体短臂上, p53基因突变是人类癌症中最常见的基因异常,目前认为野生型p53基因产物可引起细胞分化和凋亡,它的突变型则往往引起细胞增生或癌变。
短句来源
     3.The logic of Logistic return the single factor analysis manifested that there were positive relative between invasive and expression of VEGF、PCNA、MVD、P53, sex, the scope cutting off and the clinical nerve damaged performance , multifactor analysis enunciated that the clinical nerve damaged performance, the mutation or imperfections of the genes P53 and the expression of VEGF and PCNA in pituitary adenoma were main prognosis factors which influenced invasion of pituitary adenomas;
     多因素分析表明,临床视神经受损表现、VEGF、PCNA的表达、P53基因的突变或缺失情况是影响垂体腺瘤侵袭性及预后的危险因素。 结论:1.VEGF、PCNA、P53的表达在非侵袭性与侵袭性组之间有统计学意义,VEGF、PCNA、P53可作为判断垂体腺瘤侵袭性的重要指标;
短句来源
  “genes p 53”译为未确定词的双语例句
     Purpose To investigate the roles of aberrant expression of tumor suppressor genes p53、BRCA1、BRCA2、PTEN、Rb in the development of breast cancers.
     目的探讨p53、BRCA1、BRCA2、PTEN、Rb基因蛋白异常表达在乳腺癌发生中的作用。
短句来源
     The associations of some exposure factors and clinical characteristics with the expression of hMSH2 gene were analyzed. The relationships between hMSH2 gene and cancer related genes P53 ,C-MYC,K-RAS,BCL -2 and hTERT were investigated.
     并分析有关暴露因素和肺癌的临床特征对修复基因hMSH2表达的影响,以及hMSH2基因与P53、C-MYC、K-RAS、BCL-2和hTERT等癌变相关基因的关系;
短句来源
     Objective To study the different expressions of apoptotic genes p53 and Bcl-2 and their significance in the oncogenesis of SCLC and NSCLC. ?
     目的 研究小细胞肺癌 (SCLC)与非小细胞肺癌 (NSCLC)中p53与Bcl- 2基因表达的差异及意义 ,探讨SCLC与NSCLC凋亡基因调控的异同。
短句来源
     Apoptosis is controlled by many genes, P53, Bcl-2 and Bax are genes that have been more heavily studied in the research of apoptosis.
     细胞凋亡受多种基因调控,P53、Bcl-2和Bax基因是细胞凋亡研究中最受关注的癌基因。
短句来源
     It was believed that mutation or amplification of oncogenes c-ras, c-erbB-2, K-sam, c-met, and c-myc and inactivation of tumor suppressor genes p53, adenomatosis polyposis coli (APC), deleted in colorectal carcinomas (DCC), and retinoblastoma (RBI) are related to the development of gastric cancer.
     致癌基因c-ras,c-erbB-2,K-sam,c-met和c-myc的突变或者扩增以及肿瘤抑制基因p53,结肠腺瘤息肉基因(APC),结直肠癌删除基因(DCC)和视网膜母细胞瘤基因(RBI)的失活被认为与胃癌的发生有关。
短句来源
更多       
查询“genes p 53”译词为用户自定义的双语例句

    我想查看译文中含有:的双语例句
例句
为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法,我们为您准备了出自英文原文的大量英语例句,供您参考。
  genes p
We have analyzed the significance of tumor suppressor genes p53, p21, p16 and retinoblastoma protein (pRb) and proliferative activity for survival in 77 high grade astrocytic tumors.
      
Prognostic Value of the Expression of Tumor Suppressor Genes p53, p21, p16 and pRb, and Ki-67 Labelling in High Grade Astrocytom
      
The cRL fraction up-regulated the pro-apoptotic genes p53 and Bax and induced caspase-3 activation, and down-regulated the pro-survival gene Bcl-2 in both the lung cancer cell lines.
      
In parallel the expression of the two genes P53 (the key apoptosis regulator gene) and P21/Waf1 (the P53 target gene) has been evaluated.
      
We tested this hypothesis in breast carcinoma by immunostaining 89 stage-heterogeneous cases for the products of three genes (p53, ERBB-2, and EGFR) which are frequently altered in this tumor system.
      
更多          


This is the first report of cytogenetic study of flag leaf position in common wheat, Triti-cum aestivum L. F1 and F2 analyses by monosomics and telocentrics indicated that 2D chromosome of Chinese Spring carried at least two genes for pendulous flag leaves, ie. P1 on 2DL and P3 on 2DS; gene (s) E for erect flag leaves on the same chromosome of Xiaoyan No. 6. Gene P1 expressed fully, and P2 partially. Relativizing gene E, P1 and P2 were dominant and recessive...

This is the first report of cytogenetic study of flag leaf position in common wheat, Triti-cum aestivum L. F1 and F2 analyses by monosomics and telocentrics indicated that 2D chromosome of Chinese Spring carried at least two genes for pendulous flag leaves, ie. P1 on 2DL and P3 on 2DS; gene (s) E for erect flag leaves on the same chromosome of Xiaoyan No. 6. Gene P1 expressed fully, and P2 partially. Relativizing gene E, P1 and P2 were dominant and recessive respectively, and vice versa. The chromosome manipulation of these genes was also discussed.

本文首次对小麦旗叶姿态进行了比较系统的细胞遗传学研究。单体、端体的F_1及F_2分析表明:中国春2D染色体上至少有两个旗叶下披基因,即位于2DL上的P_1和2DS上的P_2,前者表达能力很强,后者则较弱,与小偃6号旗叶直立基因共存时分别表现为显性和隐性;小偃6号的旗叶直立基因E也位于2D染色体上,同(P_1+P_2)共存时表现为隐性,仅与P_2共存时则表现为显性。文章还就这些基因的染色体操作等进行了讨论。

Allelotype and point mutation of p53 exon 7 were detected in 45 pairs of primary hepatocellular carcinoma (PHC) by restriction fragment length polymorphism (RFLP) and polymerase chain reaction (PCR). Thirty -one gene markers covered 14 chromosomes were used including suppressor genes p53 and RB1. The results showed 19 gene markers covered 8 chromosomes revealed loss of heterozygosity. Six of 28 informative cases showed loss on 6q21 using probe pJCZ30, which had not been reported before. The allele...

Allelotype and point mutation of p53 exon 7 were detected in 45 pairs of primary hepatocellular carcinoma (PHC) by restriction fragment length polymorphism (RFLP) and polymerase chain reaction (PCR). Thirty -one gene markers covered 14 chromosomes were used including suppressor genes p53 and RB1. The results showed 19 gene markers covered 8 chromosomes revealed loss of heterozygosity. Six of 28 informative cases showed loss on 6q21 using probe pJCZ30, which had not been reported before. The allele loss was low frequent on the other chromosomes including p53 and RBI.Fourty-five cases of PHC from areas of low aflatoxin Bl (AFB1) exposure but high risk to HBV were examined for identifying point mutation of p53 exon 7 by PCR and restriction enzyme analysis using Rsa Ⅰ, Msp Ⅰ, Hae Ⅲ site at codon 229, 247 and 249, respectively. Two of 45 cases showed point mutation at codon 247 and 249, respectively. Our results indicated that changes of molecular genetics on PHC is a complex event, and there are multiple steps, and multiple genes are involved in hepatocarcinogenesis. Meanwhile, the results supported the postulated role of AFB1 together with HBV in the generation of specific mutation of the p53 gene provide evidence to suggest that HBV infection alone-or exposure to AFB1 alone do not contribute to these base changes.

作者应用Southern杂交和PCR扩增技术,分析了45例配对的原发性肝癌及其癌旁肝组织的等位基因型和p53第七外显子的突变状况.共应用了位于14对染色体的31个基因标志,结果在8对染色体的19个基因位点出现不同程度的杂合型丢失(LOH),丢失频率3.2%~23.5%.其中第6对染色体的pJCZ30位点的LOH为首次报告.应用PCR扩增后限制性酶切,分析了p53第七外显子的229,247和249三个密码子,结果仅2例癌组织分别在247和249密码子出现点突变.本实验结果表明,原发性肝癌的分子遗传学变化是复杂的,不同原因(HBV,黄曲霉毒素)相关的原发性肝癌,其等位基因的变化和LOH的频率存在差异,特别是p53基因第249密码子的特征性点突变差别显著,说明原发性肝癌的发生是一多基因变化,多步骤的过程.

24 female Goats were superovulated with Gonadotrophins. About 48h after first mating,total 155 ova were recovered from 16 stimulated donors. The ova recovery rate was 79.08%(155/196).The average number of ova produced by per donor was about 12.25%(196/16). Pronuclei or nuclei in atotal of 65 one-celled zygotes and 29 two-four cell stage embryos were visualized under Normarski IC microscope, and microinjected with Human Growth Hormone Gene(p~(SMGHI)/BamHI) respectively. 91 injected zygotes and embryos...

24 female Goats were superovulated with Gonadotrophins. About 48h after first mating,total 155 ova were recovered from 16 stimulated donors. The ova recovery rate was 79.08%(155/196).The average number of ova produced by per donor was about 12.25%(196/16). Pronuclei or nuclei in atotal of 65 one-celled zygotes and 29 two-four cell stage embryos were visualized under Normarski IC microscope, and microinjected with Human Growth Hormone Gene(p~(SMGHI)/BamHI) respectively. 91 injected zygotes and embryos were transferred surgically into 14 synchronized recipients. After embryotransfer, 7 recipients became pregnant, and total 12 lambs were born, 11 alive and one dead at parturition.The frequency of hGH integration was examinated by using DNA probes labeled with NonradioactiveDigoxigenin. Results showed that 4 in 12 tested lambs carried the foreign genes, the integration frequencywas 33.33%(4/12). Gene expression in 4 living lambs (2 hGH gene integration positive, 2 negative) wasdetected by ELISA, and no one exprcsscd humane Growth Hormone in plasma.

对24头供体山羊进行超数排卵处理,16头超排有效。在第1次配种后48h左右取卵,共收集到卵155个。回收率79.08%(155/16)。平均每头供体排卵12.25个(196/16)。在Normarski干涉相差显微镜下观察65个单细胞受精卵及29个2~4细胞期胚胎的原核及细胞核,并分别注射人生长激素基因(p~(SMGHI)/BamHI),其中91枚移植到经同期发情处理的14头受体中。结果7头妊娠,共产活羔11头,死胎1头。经用Digoxigcnin标记核酸探针对转移基因羊检测,4头整合了外源基因。整合频率为33.33%(4/12)。采用酶联免疫吸附法(ELISA)对仍存活的2头未整合、2头整合羊检测是否表达外源基因,全为阴性。

 
<< 更多相关文摘    
图标索引 相关查询

 


 
CNKI小工具
在英文学术搜索中查有关genes p 53的内容
在知识搜索中查有关genes p 53的内容
在数字搜索中查有关genes p 53的内容
在概念知识元中查有关genes p 53的内容
在学术趋势中查有关genes p 53的内容
 
 

CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社