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    The Lung Involvement of Systemic Lupus Erythemotosus Analysis of Clinical and Pathological Changes in 15 Autopsied Cases
    15例尸检系统性红斑狼疮肺和胸膜病变的临床病理分析
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The following principle is well-known in Harmonic Analysis: If a real function has a spectral gap at the origin then it must have many sign changes.
      
The study shows that government has made some important changes after the signing of WTO agreement in 1994, but there are still some contentious issues that require attention.
      
The series of vasicine (1) analogues, an alkaloid from Adhatoda vasica Nees., were synthesized with changes in A, B or C rings.
      
Roridin P and Isororidin P induced morphological changes in Pyricularia oryzae, with a minimum concentration (MMCC) value of 6.2 ± 1.1?μmol/L and 7.9 ± 1.5?μmol/L.
      
Based on the literature [1], this paper changes the essential conditionα ∫g(t)/tr(s)ds ≤ 1 into∫g(t)/tr(s)ds ≤θ.
      
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Chinese herb Lei-Gong-Teng (Trigterygivm Wilfordii Hook F.)and its extracts were used in the treatmentd of 284 cases of Type Ⅱ lepra reaction. Complete remission of the reactional syndrome>was observed in 257 cases(90.49%), improvement in 24 cases ( 8.46% ), no change in 2 cases ( 0.7% ), and deterioration in 1 case(0.35%).Results were comparable to that of thalidomide (a group served as a control ) in rapid subsidence of erythema nodosum ( ENL ) , fall in temperature, relief of nerve pain and fall in...

Chinese herb Lei-Gong-Teng (Trigterygivm Wilfordii Hook F.)and its extracts were used in the treatmentd of 284 cases of Type Ⅱ lepra reaction. Complete remission of the reactional syndrome>was observed in 257 cases(90.49%), improvement in 24 cases ( 8.46% ), no change in 2 cases ( 0.7% ), and deterioration in 1 case(0.35%).Results were comparable to that of thalidomide (a group served as a control ) in rapid subsidence of erythema nodosum ( ENL ) , fall in temperature, relief of nerve pain and fall in erythrocyte sedimentation rate.Thirty-four cases of Type Ⅰ lepra reaction received Lei-Gong-Teng. Improvement was observed in 32 cases ( 94.1% ) and no change in 2 cases ( 5.9%).The average time of beginning improvement of erythema was 4.5 days, nerve pain was 6.3 days, edema was 3 days and fever was 4 days. As we know thalidomide is of no effect on these cases, therefore, in Type Ⅰ lepra reaction Lei-Gong-Teng was probably shown to be superior to thalidomide.The side effects of Lei-Gong-Teng mainly limited to gastrointestinal distress and leucopenia. In 205 cases of Type Ⅱ lepra reaction received Lei-Gong-Teng, 62 cases ( 30.24% ) had gastrointestinal distress, such as anorexia, vomiting, stomach burning, diarrhea, abdominal pain etc.One hundred and ninety-five cases of Type Ⅱ lepra reaction received Lei-Gong Teng leucopenia was observed in 7 cases(3.6%) ( <4000/mm3) .Thirty-four cases of Type I lepra reaction treated with Lei-Gong-Teng, gastrointestinal distress was observed in 16 cases (47.1%) .In 22 cases of Type I lepra reactibn received Lei-Gong-Teng leucopenia was obsrved in 6 cases (27.3%) .After discontinuing the therapy, all side effects gradually subsided.One hundred and thirteen cases of Type Ⅱ lepra reaction treated with thalidomide, 47 cases ( 41.6% ) had side effects, such as dizziness, drowsiness, constipation, dryness of the oral and nasal mucosa, diarrhea, epigastric pain etc.The side effects of the extracts of Lei-Gong-Teng("104", "124" ) were slighter than that of Lei-Gong-Teng herb.

中药雷公藤治疗Ⅱ型麻风反应284例次,有效者281例次,有效率98.95%,对照组反应停治疗Ⅱ型麻风反应113例次,有效者109例次,有效率96.4%。雷公藤治疗Ⅰ型麻风反应34例次,有效者32例次,有效率94.1%,反应停对Ⅰ型麻风反应无效。根据临床和化验室检查,雷公藤对Ⅱ型麻风反应的疗效不亚于反应停,对Ⅰ型麻风反应的疗效可能优于反应停。雷公藤药源丰富,使用方便,其提取物“104”和“124”的副作用很少。

Phytohaemagglutinin (PHA) can cause delayed hypersensitivity reaction in vivo. We had observed skin tests to PHA in 121 healthy children and adults, and studied the histological changes to PHA in a guinea pig (GP). The sujects of study were iniected intradermally with PHA in a dose of 67 μg/0.1 ml. The diameters on the reacted areas with erythema and induration were measured after different time intervals. Biopsy of skin test in the GP showed that it was mainly subcutaneous edema 4 hours after injection,...

Phytohaemagglutinin (PHA) can cause delayed hypersensitivity reaction in vivo. We had observed skin tests to PHA in 121 healthy children and adults, and studied the histological changes to PHA in a guinea pig (GP). The sujects of study were iniected intradermally with PHA in a dose of 67 μg/0.1 ml. The diameters on the reacted areas with erythema and induration were measured after different time intervals. Biopsy of skin test in the GP showed that it was mainly subcutaneous edema 4 hours after injection, and infiltration of monocytes 8 hours after injection. The diameter of erythema was taken as the standard measurement since the dynamic diagram of curves from diameters of erythema and induration showed an approximate parallel relation

植物血凝素(PHA)在体内能引起迟缓型变态反应。我们对121名健康儿童和成人进行了PHA皮试观察;对豚鼠作了组织学观察。方法是皮内注射67μg/0.1 ml,,分别于0.5、1、2、4、8、12和24小时测量红斑和硬结的直径。结果豚鼠皮试证明,4小时前以皮下水肿为主,8小时后以单核细胞浸润为主。1岁以上各年龄组健康人PHA皮试变异不大。PHA皮试动态观察证明,红斑和硬结直径有近似平行的关系,采用红斑直径作为判断标志。

A clinical analysis of 242 cases of systemic lupus erythematosus (SLE) was presented. Among them, 22 were male and 220 female, which gave a male/female ratio 1:10. 77.7% of the cases ranged from 11-40 years old. Clinically, fever and arthralgia (including arthritis)were most commonly seen while skin lesions, renal impairment, cardiovascular and haematological changes were next in frequency. The fluorescent antinuclear antibody test is usually the most sensitive one for the detection of autoantibodies....

A clinical analysis of 242 cases of systemic lupus erythematosus (SLE) was presented. Among them, 22 were male and 220 female, which gave a male/female ratio 1:10. 77.7% of the cases ranged from 11-40 years old. Clinically, fever and arthralgia (including arthritis)were most commonly seen while skin lesions, renal impairment, cardiovascular and haematological changes were next in frequency. The fluorescent antinuclear antibody test is usually the most sensitive one for the detection of autoantibodies. With repeated blood examinations, the positive findings of LE cells usually clinched the diagnosis. Erythcma, thrombocytopenic purpura and Raynaud's phenomenon might appear several years prior to other symptoms of SLE, which should call for a due attention in clinical practice. The diagnosis cf SLE and the overlap syndrome were briefly discussed.

本文报道系统性红斑狼疮242例的临床资料。从首发症状及临床表现分析:发热、关节痛(炎)最多见,其次为皮疹、肾脏损害及心血管与血液学改变。实验室检查以抗核因子最灵敏,LE细胞阳性率也高,且简便易行。盘状红斑、血小板减少性紫癜与雷诺氏现象等可先于SLE,其它症状数年出现,应引起警惕。本文同时对SLE的诊断与重叠综合征作了简要讨论。

 
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