Apoptotic cell density was: non-tumor mucosa 15.02 ± 11.14, tubular adenoma 46.31 ± 18.86, tubulo-villous adenoma 29.43 ± 16.66, non-malignantly transformed area of adenoma 68.42 ± 19.61, malignantly transformed area of adenoma 22.01 ± 12.07, adenocardnoma 18.64 ± 12.88, which was higher in adenomas, but lower in malignant lesions (P<0.001).
Cubilin, an endocytic receptor expressed on the renal tubular brush border, is responsible for albumin reabsorption in physiologic condition.
However, little is known about whether it is required for activation of tubular cells induced by albumin overload.
The intensity of luminal cubilin and tubular accumulation of albumin were significantly increased in nephrotic kidneys.
Cubilin was required for handling a greater amount of protein in nephrotic status and albumin-induced production of MCP-1 and RANTES by renal tubular cells, which further initiated tubulointerstitial inflammation in proteinuric disease.
The effects of temperature and time on polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) distribution in fly ash of a municipal solid waste incinerator (MSWI) were studied in a tubular oven under nitrogen atmosphere.