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allograft     
相关语句
  移植
    The Skin-repair after Combination of Allograft and Autograft Transplantation for Extensive Burn Patients
    大面积烧伤患者异体皮和自体皮混会移植后的皮肤修复
短句来源
    Measurement of Serum sVCAM 1 in Renal Allograft Recipients and Its Clinical Implications
    血清可溶性血管细胞粘附分子1测定在肾移植急性排斥反应中的临床意义
短句来源
    Experimental study on the mechanisms of immune privilege in corneal allograft rejection
    角膜移植免疫赦免机制的实验研究
短句来源
    Cardiac allograft and myocardial necrosis in rats.
    大鼠心脏移植与心肌细胞坏死
短句来源
    Intragraft expression of IL 2R and ICAM 1 during small intestinal allograft rejection episode
    小肠移植急性排斥反应期移植肠白细胞介素2受体和细胞间粘附分子1的表达
短句来源
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  异体移植
    Experimental study on reconstruction of the blood vessles after autograft and allograft of swine composite chitosan tissue engineered skin
    猪组织工程皮肤自体及异体移植后血管重建的实验研究
短句来源
    Construction of articular chondrocyte-scaffold construction and morphologic observation of allograft to repair articular cartilage defect
    细胞-支架复合体构建及其异体移植修复关节软骨缺损的形态学观察
短句来源
    Objective To evaluate the effectiveness and feasibility of the articular chondrocyte-scaffold construct as allograft to repair articular cartilage defect based on tissue engineering.
    目的 探讨应用组织工程技术进行异体移植修复关节软骨缺损的有效性和可行性。
短句来源
    The gross and histological features of the allograft cells-scaffold constructs were as follows: ①the articular surface was smooth and well-integrated with adjacent tissues;
    其细胞 支架复合体异体移植修复关节软骨缺损的病理形态学特征为 :①修复后的关节面光滑 ,与周围组织整合良好 ;
短句来源
  同种异体移植
    The characteristics of B7 expression in allograft biopsies of acute cellular rejection in renal transplantation
    同种异体移植肾组织中B7蛋白的表达及其意义
短句来源
    Research of expression of RANTES in rat external ear allograft
    同种异体移植大鼠耳廓组织中RANTES表达的实验研究
短句来源
    ConclusionWounds maybe healed well after autograft and allograft. The basement membrane of tissue engineered skin is well.
    结论我们构建的猪组织工程皮肤自体及同种异体移植后,可获得理想的创面愈合效果,组织工程皮肤基底膜形成完整,与正常皮肤相似。
短句来源
    Scaffold of acellular tissue engineered artificial facial nerve allograft
    去细胞同种异体移植面神经材料的制备
短句来源
    Acellular Scaffold for Tissue Engineered Facial Nerve Allograft.
    去细胞同种异体移植面神经材料的制备
短句来源
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  同种移植
    The Effects of Cyclosporin a on the Antigen Presenting Function of Mice Immature Dendritic Cells and Allograft Tolerance
    环孢素A对小鼠未成熟树突状细胞抗原递呈功能和同种移植耐受的影响
短句来源
    Combined treatment of allograft recipients with CTLA-4 Ig and anti-ICAM-1 mAb plus transfusion of donor-specific DC progenitors
    CTLA-4Ig与ICAM-1单抗联合DCp诱导同种移植耐受
短句来源
    ( P <0.01)Conclusion:These results suggest that:(1)CMXR is much stronger than allograft rejection,in which CD4 +T cells and ED2 +MΦ are the major infiltrating cells and the Th2 type cytokines are higher in xenografts that those of in allografts.
    结论 :CMXR与同种移植急性排斥反应存在本质差异 ,其特点是排斥程度强烈 ,异种移植胎肠内以CD4 +T细胞和ED2 +MΦ浸润为主 ,且Th2细胞功能增强。
短句来源
    Objectives To investigate the effects of Cyclosporin A(CsA) on the antigen presenting function of mice immature dendritic cells(DC) and allograft tolerance.
    目的:研究环孢素A对小鼠树突状细胞抗原递呈功能及其对同种移植耐受的影响。
短句来源
    Results CsA can delay the mature process of mice immature dendritic cells, inhibit its function of antigen presentation, indicated by the downregulated expression of MHC and co-stimulatory molecules, secretion of IL-12 significantly decreased, being significant against controls; DCs treated with CsA can prolong the survival of allograft, inhibit reaction to allogeneic T cells, contribute to Thl/Th2 deviation and formation of microchimerisms.
    结果环孢素A延缓小鼠树突状细胞成熟,抑制MHC和共刺激分子表达以及IL-12的分泌,与对照组有显著性差异:环孢素A作用的树突状细胞可延长小鼠同种移植心脏存活,降低受体T细胞反应性,促使嵌合体形成。
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  allograft
A proteomic analysis of allograft rejection in rats after liver transplantation
      
In order to understand the allograft rejection in orthotopic liver transplantation (OLT), an allograft rejection rat model was established and studied by proteomic approach.
      
The results of the present paper could be helpful for our better understanding of allograft rejection in organ transplantation.
      
Co-expression of sCD40LIg and CTLA4Ig mediated by adenovirus prolonged mouse skin allograft survival
      
Simultaneous blockade of CD40/CD40L and B7/CD28 costimulatory pathway mediated by replication-defective adenovirus significantly prolonged skin allograft survival in mice.
      
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Accelerated and enhanced mixed lymphocyte reaction (MLR) and skin allograft rejection (SAR) were observed in mice sensitized with related alloantigens. The period of time during which the allo-specific secondary MLR and "second-set" allo-graft rejection could be detected was found to be different. It was shorter for the former and longer for the latter.

被同种异体抗原致敏的受者小鼠,对有关供者混合淋巴细胞反应(Mixed lymphocyte reaction,简称MLR)和移植皮片再次排异反应,都显示反应得到加速和增强。这种改变与抗原特异性有关,但致敏小鼠的MLR与皮片再次排异反应,所能检测的特异性再次免疫反应,维持的时间不同,前者较短而后者较长。

Sixc ases with burn of 39-95% of body surface and 4-7% third degree burn were studied. The third degree burn were treated with combination of allograft and autograft. Biopsies were obtainded from areas of allograft, autograft and the junction of allograft and autograft during the dressing changes in different stages. The allograft epithelium was intact in the third day, but showed pyknosis and karyolysis after fourth day. The autograft epithelium showed hyperolasia early in the fourth...

Sixc ases with burn of 39-95% of body surface and 4-7% third degree burn were studied. The third degree burn were treated with combination of allograft and autograft. Biopsies were obtainded from areas of allograft, autograft and the junction of allograft and autograft during the dressing changes in different stages. The allograft epithelium was intact in the third day, but showed pyknosis and karyolysis after fourth day. The autograft epithelium showed hyperolasia early in the fourth day and began to extend under the allograft. From the eleventh to nineteenth day the active hyperplastic autograft epithelium eytended under allograft and replaced it, while the dead allograft sloughed off. The skin-repair following the combination of allograft and autograft transplantation is a complex process, which includes the allograft survival and the rejection, as well as hyperplasia and injury of autograft. The open wound is clinically nonvisible after grafting, althouth the rejection is still carried. There was no hyperplasia of allograft epithelium observed.Key words: allograft, autograft.

六例烧伤总面积在39~95%,三度烧伤面积在4~7%的病人,以异体和自体皮混合移植处理三度烧伤创面。皮肤移植后不同时期换敷料时取异体皮、自体皮、异体皮和自体皮交错处的活检观察皮肤再生长情况。在移植后第三天异体皮上皮尚完整,第四天显示有核缩、核溶。自体皮上皮早在第四天已有增生,并且开始伸至导体皮下。从第11天到第19天活跃增生的自体皮上皮伸入异体皮下,并替代之。死灭的异体皮从受体脱落。异体皮和自体皮混合移植后的皮肤再生长是一个很复杂的过程,包括异体皮的存活和排异反应,以及自体皮的增生及损伤。用这个方法移植后,临床上见不到开放创面,但排异反应依然存在。异体皮上皮的增生没有见到。

057BL/6 strain (H-2b) newborn mice were injected i.p. with lymphocytes from spleens and lymph nodes of adult (C57BL/6 × DBA/2) F1 mice (H-2b/d) .24 hrg later, some erf the mice received a farther injection of IL-2 (26U per mouse), others received normal saline as controls. When grown up, all mice were given heart allograft from DBA/2 mice (H-2d). The median survival time of allografts (14.9 days) in mice receiving IL-2 injection soon after birth was significantly shorter than that (42.9 days) in control...

057BL/6 strain (H-2b) newborn mice were injected i.p. with lymphocytes from spleens and lymph nodes of adult (C57BL/6 × DBA/2) F1 mice (H-2b/d) .24 hrg later, some erf the mice received a farther injection of IL-2 (26U per mouse), others received normal saline as controls. When grown up, all mice were given heart allograft from DBA/2 mice (H-2d). The median survival time of allografts (14.9 days) in mice receiving IL-2 injection soon after birth was significantly shorter than that (42.9 days) in control mice. The spleen cell response to alloantigens (F1 cell) was significantly lower in the MLE system in newborn mice than that in adult mice (S. I. 1.01 vs 8.78). Howevar the low response to alloantigens in newborn mice was partially enhanced when exogenous IL-2 was added into the MLR system (S. I.1.98). In ohimerism assay, the percentage of F1 chimerio cells in spleens from mice receiving IL-2 soon after birth was much lower than that in spleens from controls. When spleen cells were stimulated by Con A, the activity of IL-2 produced was undetectable in newborn mice while it was 0.24 U/ml, 1.19 U/ml and 9.3 U/ml in 3-day-old, 8-day-old and adult mice respectively.These results indicate that ease of tolerance induction in newborn mice may be ascribed to a low immune response for elimination of allogeneio cells due to IL-2 production deficiency.

用(C 57BL/6×DBA/2)F_1淋巴细胞注射至新生C57BL/6小鼠腹腔,可诱导其针对DBA/2小鼠心肌移植物的耐受性,但在注射F_1细胞后24h再向受鼠补充外源性白细胞介素2(IL-2)时,则不能诱导出耐受。用混合淋巴细胞反应(MLR)实验系统观察到新生小鼠的同种免疫反应能力明显低于成年小鼠,但外源性IL-2能部分提高该反应能力。分析嵌合体时发现,耐受鼠体内F_1细胞嵌合率明显高于补充IL-2后耐受被破坏的小鼠。另外,用Con A在体外诱生不同年龄小鼠脾细胞产生IL-2,结果表明,新生小鼠脾细胞未能诱生出可测知的IL-2活性,而随年龄增长直到成年,IL-2诱生能力不断上升。提示新生小鼠易于诱导移植耐受与它IL-2分泌低下,不足以激发同种免疫应答反应而无法清除同种细胞有关。

 
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