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   hematological malignancy 的翻译结果: 查询用时:0.174秒
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心血管系统疾病
肿瘤学
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hematological malignancy
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  恶性血液病
     Results: The expression of p170 were 45.0% in the hematological malignancy patients with untreated,the expression of peripheral blood p170 were 30.7% in the patients with AL untreated.
     结果 :初治恶性血液病患者 p170阳性表达率45 .0 % ,初治急性白血病外周血 p170高表达占 30 .7%。
短句来源
     We measured serum levels of soluble Fas(sFas) in 68 patients with hematological malignancy by using sandwich ELISA and detected bone marrow mononuclear cell membrane Fas(mFas) positive cells in 46 patients with acute leukemias by immunohistochemical technic.
     用ELISA法测定68例恶性血液病患者血清可溶性48kD跨膜糖蛋白(sFas)水平,用免疫组织化学SABC法检测其中46例急性白血病患者骨髓单个核细胞膜Fas(mFas)阳性表达细胞数。
短句来源
     METHODS Sixty patients (M 34,F 26),age (42±15)a,with leucopenia after the chemotherapy for hematological malignancy were divided at random into 2 groups,treatment group and control group.
     方法 选择恶性血液病化疗后WBC减少期患者6 0例(男34例,女2 6例) ,年龄(42±15 )a,随机分为2组。
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     Clinical study of umbilical cord blood transplantation in patients with hematological malignancy
     脐血移植治疗恶性血液病的临床研究
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     Conclusion: Itraconazole injection is effective and safe in treatment of invasive fungal infections in patients with hematological malignancy
     结论伊曲康唑注射液对恶性血液病合并侵袭性真菌感染疗效显著,对存在危险因素的患者早期诊断,积极治疗,可取得良好效果。
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  血液肿瘤
     Alterations in the serum levels of TNF and TGF-α in patients with hematological malignancy and their clinical significance
     血液肿瘤患者血清TNF、TGF-α的水平及临床意义
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     This study is to determine whether induction high dose EPO followed by weekly maintenance usage could improve hemoglobin (Hb) levels in anemic hematological malignancy patients receiving chemotherapy. Methods The open-label, nonrandomized clinical study evaluated the response rate of induction EPO 120,000 U (40,000 U SC d1、d3、d5) followed by maintenance dose of 40,000 U SC once weekly for 3 weeks (d8、d15、d22).
     方法采用开放性非随机的临床研究方法,恶性血液肿瘤患者在化疗同时,于第1周采用EPO120,000U冲击用药(40,000U皮下d1、d3、d5),随后EPO每周40,000U皮下(d8、d15、d22)维持用药,共4周。
短句来源
     Clinical Study of Induction high dose therapy followed by Main- tenance with EPO in Anemic Hematological Malignancy Patients
     红细胞生成素大剂量冲击维持疗法治疗血液肿瘤贫血的临床研究
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     A clinical study of dental extraction in pediatric patients with hematological malignancy
     血液肿瘤患儿拔牙安全性的临床研究
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     ObjectiveTo study alterations in the serum levels and the clinical significance of TNF and TGF-α in patients with hematological malignancy.
     目的 探究TNF和TGF α在血液肿瘤性疾病中的变化和病情及预后的关系。
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  血液恶性肿瘤
     Objective To evaluate the expression and clinical significance of tumor specific growth factor(TSGF) in blood serum for hematological malignancy.
     目的探讨血清肿瘤特异性生长因子(TSGF)在血液恶性肿瘤患者中的表达和临床意义。
短句来源
  “hematological malignancy”译为未确定词的双语例句
     Non-Hodgkin's lymphoma(NHL) is a common hematological malignancy with high mortality.
     非霍奇金淋巴瘤(non-Hodgkin's lymphoma, NHL)是一种常见的血液系统恶性肿瘤,死亡率较高。
短句来源
     Objective To investigate the clinical significance of the changes of plasma von Willebrand factor (vWF),D-dimer (D-D) and antithrombin (AT) levels in patients with hematological malignancy.
     目的探讨血液系统肿瘤患者血浆中血管性血友病因子(vWF)、D二聚体(D-D)、抗凝血酶(AT)水平变化及临床意义。
短句来源
     Results The overall frequency of active tuberculosis was 1.5‰ new cancer diagnosis during the 21 years of the study. Tuberculosis occurred in 29(57%)patients with solid-organ malignancy and 22(43%)patients with hematological malignancy,the prevalence of tuberculosis was 0.9‰ and 7.7‰ respectively.
     结果51例患者占同期我院诊断恶性肿瘤患者总数的1·5‰,其中实体瘤并发结核患者29/51例(57%),占同期实体瘤患者的0·9‰,血液系统恶性肿瘤22/51例(43%),占7·7‰。
短句来源
     Methods: Hematological malignancy cell lines MUTZ-1,K562,Jurkat,RPMI and HL60 were treated with HHT in vitro.
     方法:应用流式细胞仪技术,研究HHT诱导人骨髓增生异常综合征细胞株MUTZ-1、人急性红白血病细胞株K 562、人淋巴瘤细胞株Jurkat和人骨髓瘤细胞株RPM I,以及人急性粒细胞白血病细胞株HL 60细胞凋亡。
短句来源
     Objective:To investigate the changes of lymphocyte subsets and CD34~(+) cells in the peripheral blood(PB) of patients with hematological malignancy mobilized with rhG-CSF.
     目的:动态观察自体外周血造血干细胞移植患者经rhG-CSF动员过程中外周血及外周血造血干细胞(PBPC)中淋巴细胞亚群和CD34+细胞的变化,指导临床选择最佳采集时机。
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  hematological malignancy
Multiple Myeloma (MM) is a hematological malignancy which will affect 14,000 new individuals in the United States in 2001 and remains irreversibly fatal despite all available therapies.
      
The patients were classified into three groups according to clinical diagnosis: idiopathic thrombocytopenic purpura (ITP) (n = 23), hemolytic anemia (HA) (n = 5), and hematological malignancy (HM) (n = 15).
      
In this communication the authors have reviewed different articles describing the association between breast feeding (BF) and subsequent development of childhood hematological malignancy.
      
Breast feeding and childhood hematological malignancy
      
This kind of hematological malignancy is severe and carries a bleak prognosis.
      
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Measurements of ADA activity might behelpful in the diagnosis of a wide varietyof hematological malignancies and immuno-deficiency disease. To establish thenormal value of ADA activity in theChinese will be of great importance, butno such data have ever been reported. This paper reports a study of normalvalue of ADA activity by ammonia gas-sensing electrode method for 329 healthysubjects in Chengdu, Sichuan aged from 0 to74,all measures were taken under random-ized condition. Statistical analysis wasmade...

Measurements of ADA activity might behelpful in the diagnosis of a wide varietyof hematological malignancies and immuno-deficiency disease. To establish thenormal value of ADA activity in theChinese will be of great importance, butno such data have ever been reported. This paper reports a study of normalvalue of ADA activity by ammonia gas-sensing electrode method for 329 healthysubjects in Chengdu, Sichuan aged from 0 to74,all measures were taken under random-ized condition. Statistical analysis wasmade on different age groups.It was foundthat the ADA activity in whole bloodranges from 10.00 to 39.81 units. The upper limit of ADA activity in thechildren group at 95% level is 46.46 unitsand the lower is 9.89 units; the upperlimit of the adult group at the same levelis 42.98 units and the lower is 8.81 unitson the basis of statistics in percentage.TheADA activity of adult is lower than thatof the children group (P<0.01).

本文报道了用氨气敏电极法测定329例正常人血腺苷脱氨酶活性,大多数人在10. 00~39.81单位之间;儿童与成年人存在显著性差异(P<0.01),儿童组M±SD=26.58±10.08单位,成人组M±SD=20.01±9.36单位。儿童正常值95%上限为46.46单位,下限为9.89单位;成人正常值95%上限为42.98单位,下限为8.81单位。

The therapeutic effect of ceftizoxime (CZX) in 24 patients (M14, F10, age 46±16yr) with hematological malignencies complicated by severe infections is reported. The daily dose of CZX was 4-6 g iv with an average total dosage of 41 ± 16g. Excellent response was noted in 38% and fair in 25%. The total response rate was 62%. CZX was effective for both gram positive and gram negative bacterial infection, but was of no use in all 3 cases of Pseudomonas aeruginosa infection. It was also found that the response...

The therapeutic effect of ceftizoxime (CZX) in 24 patients (M14, F10, age 46±16yr) with hematological malignencies complicated by severe infections is reported. The daily dose of CZX was 4-6 g iv with an average total dosage of 41 ± 16g. Excellent response was noted in 38% and fair in 25%. The total response rate was 62%. CZX was effective for both gram positive and gram negative bacterial infection, but was of no use in all 3 cases of Pseudomonas aeruginosa infection. It was also found that the response of treatment was better for patients with neutrophil count above 1.0xl09/L than those below this level. Adverse effect was slight. Yellowish color vision was noted in* a patient, which disappeared after withdrawal of the drug. No fever or drug rash was noticed. It is suggested that CZX is a safe and useful broad-spectrum antibiotics for the treatment of severe infection complicating hematological malignancies.

本文报道头孢唑肟(ceftizoxime)治疗24例(男14例,女10例,平均年龄46±16yr)恶性血液病并发重症感染。剂量为4-6g/d,iv,总剂量平均为41±16g,结果显效38%,有效25%;总有效率62%,头孢唑肟对革兰阳性菌和阴性菌均有效,但对绿脓杆菌感染无效。患者中性粒细胞绝对计数高于1.0×10~9/L的有效率高。本药副作用轻微,是一种安全,有效的广谐抗生素。

Chronic myeloid leukemia (CML) is a hematological malignancy characterized by a reciprocal translocation t (9;22), that results in the fused bcr/abl gene and the chimeric 8.5kb transcript. The transformative activity of the bcr/abl gene has been confirmed by introducing bcr/abl constructs in mice. Furthermore, leukemic colony formation is selectively suppressed when CML blast cells are exposed to synthetic oligodeoxynucleotides complementary to bcr/abl gene junction region. We amplified the bcr/abl gene...

Chronic myeloid leukemia (CML) is a hematological malignancy characterized by a reciprocal translocation t (9;22), that results in the fused bcr/abl gene and the chimeric 8.5kb transcript. The transformative activity of the bcr/abl gene has been confirmed by introducing bcr/abl constructs in mice. Furthermore, leukemic colony formation is selectively suppressed when CML blast cells are exposed to synthetic oligodeoxynucleotides complementary to bcr/abl gene junction region. We amplified the bcr/abl gene junction region from K562 cell RNA using a pair of synthetic primers by RT-PCR technique and inserted it into pGEM-4Z plasmid. The PCR product was a 0.3 kb DNA fragment. Restriction analyses of the recombinant plasmids suggested that we had got the clones of the target sequence. Results from sequencing analyses supported that the plasmid, pB3A2, contained a 0.3kb fragment homologous to the b3a2-type junction region cDNA of bcr/abl gene. The plasmid pB3A2 may provide a good source of probes and antisense plasmids in further studies on selective killing of CML cells.

利用分子生物学方法,我们将K562细胞林bcr/abl mRNA 0.3kb的接合区cDNA片段用聚合酶链反应扩增并插入到质粒pGEM-4-Z载体中。经限制酶切分析和荧光标记M13引物法DNA序列测定,证实重组质粒pB3A2中有0.3kb的插入片段与K562 mRNA接合区序列完全一致。我们分离到的接合区DNA可用于bcr/abl基因的检测及其反义核酸抑制的研究。

 
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