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breast carcinoma     
相关语句
  乳腺癌
     Clinical and Experimental Study on Sentinel Lymph Nodes Biopsy of Breast Carcinoma
     乳腺癌哨兵淋巴结活检的临床和实验研究
短句来源
     Roles of NFκB in G1/S Cell Cycle Checkpoint and Apoptosis Induced by HCPT in Human Breast Carcinoma Cells
     NFκB在羟基喜树碱诱导乳腺癌细胞凋亡和细胞周期阻滞中的作用机制研究
短句来源
     To Analyse the Axillary Lymph Metastases of the Breast Carcinoma and to Investigate the Sentinel Lymph Node Biopsy
     乳腺癌腋窝淋巴结转移及前哨淋巴结活检术的探讨
短句来源
     Study on Radiommunoimaging and Radiommunotherapy with ~(131)Ⅰ-Anti-CEA, TPS Monclonal Antibody in Nude Mice Bearing Human Breast Carcinoma
     ~(131)Ⅰ标记的抗CEA、TPS单克隆抗体在荷人乳腺癌裸鼠体内的放射免疫显像及治疗的研究
短句来源
     The mRNA and Protein Expressions of TP, TS, DPD and Their Correlation with the Clinicopathological Factors and Prognosis in Breast Carcinoma.
     乳腺癌TP、TS、DPD mRNA和蛋白的表达及其与临床病理、预后关系的研究
短句来源
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  乳腺肿瘤
     Objective To explore the expression of ER,C-erbB-2,PCNA , CD40,CD138 and gelsolin in breast carcinoma, and to study the correlation between their expression and cell biological behavior of breast carcinoma cells.
     目的 研究ER、C-erbB-2、PCNA、CD40、CD138和gelsolin在乳腺肿瘤组织中的表达,探讨它们与乳腺肿瘤细胞生物学行为的相关性。
短句来源
     The expression of C-erbB-2, p53 protein in breast neoplasm and its relationship to estrogen and progestin receptor of breast carcinoma
     乳腺肿瘤中C-erbB-2 p53蛋白的表达及与激素受体的关系
短句来源
     The Transcriptive Expression and Clinical Significance of nm23H Gene in Human Breast Carcinoma with RT-PCR Method
     RT-PCR分析nm23基因在乳腺肿瘤中的转录表达
短句来源
     PURPOSE To evaluate the clinical diagnostic value of radioimmunoimaging (RII) in breast carcinoma. METHODS 7 patients with breast tumors were imaged by RII using 99m Tc labeled anti CA15 3 monoclonal antibody MACA1. The clearance of the radiolabeled antibody in blood (half time, T 1/2 ) and the biodistribution were studied.
     为评价99mTc标记抗CA153单克隆抗体(McAb)MACA1放射免疫显像(RII)诊断乳腺癌的临床价值,对7例乳腺肿瘤患者进行RI,并测定标记McAb血液半清除时间(T1/2)和生物学分布。
短句来源
     1. The positive expression of bFGF and TGF 3 (is low in benign breast tumor, while it is high in breast carcinoma.
     1.bFGF与TGFβ1在良性乳腺肿瘤中表达较低,而在乳腺癌中表达较高。 提示bFGF与TGFβ1在乳腺癌发病发展过程中起促进作用。
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  乳腺癌组织
     Results The positive rates of C-erbB-2 ,PCNA ,ER and PR in breast carcinoma were 58.8% 56.5% ,71.8% and 67.06%,respectively.
     结果:85例乳腺癌组织中C-erbB-2、PCNA、ER和PR表达率分别为58.8%、56.5%、71.8%和67.1%。
短句来源
     Expressions of E-cadherin and CD44V6 and uPA in breast carcinoma
     乳腺癌组织中E-cadherin和CD44V6及uPA的表达及意义
短句来源
     ④PCNA-PI showed moderately negative correlation with bcl-2 (rs=-0.537) and moderately positive correlation with p53 (rs=0.628), and bcl-2, moderately negative correlation with p53 (rs=-0.476) in breast carcinoma tissue.
     ④在乳腺癌组织PCNA指数与bcl-2呈中度负相关(rs=-0.537),与p53呈中度正相关(rs=0.628),bcl-2与p53呈中度负相关(rs=-0.476)。
短句来源
     Expression of uPA,uPAR and nm23-H1 gene in human breast carcinoma
     乳腺癌组织中uPA、uPAR及nm23-H1的表达
短句来源
     ② Results of PCR-SSCP: The polymorphisms of two P21WAF1 gene were 24.2% (29/120) in the breast carcinoma and 6.0% (3/50) in the benign breast tissue, significantly higher in the former than in the latter (P < 0.05).
     ②聚合酶链反应单链构象多态性检测结果:120例乳腺癌和50例良性乳腺组织P21WAF1基因多态性分别为24.2%(29/120)和6.0%(3/50),乳腺癌组织高于良性乳腺组织,两组间差异有显著性(P<0.05)。
短句来源
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  乳癌
     Expression of nm23,MMP-2,TIMP-2 in breast carcinoma tissue
     乳癌组织中nm23、MMP-2、TIMP-2蛋白的表达
短句来源
     Results: The positive rates of Bcl 2 protein, P53 protein, ER, and PR in breast carcinoma tissues were 65.2%, 47.5%,75.4%, and 69.6% respectively.
     结果 :Bcl 2蛋白 ,P53蛋白 ,ER ,PR在乳癌组织中表达的阳性率分别为 65 .2 % ,47.5 % ,75 .4 % ,69.6 % ;
短句来源
     Expression of Mutant P53,nm23-H1 Gene Proteins and Its Clinical Significance in Breast Carcinoma
     乳癌中突变P53和nm23-H1基因的表达及临床意义
短句来源
     Results (1) Positive expression rates of GST Pi,ToPoII and PgP in 52 cases of breast carcinoma were 50.0% (26/52), 17.3% (9/52) and 11.5%(6/52),respectively.
     结果  (1) 5 2例乳癌中的GST Pi ,ToPoII和PgP的阳性表达率分别为 5 0 .0 % (2 6/ 5 2 ) ,17.3 % (9/ 5 2 )和 11.5 % (6/ 5 2 ) ;
短句来源
     Significant correlation existed between the decrease of the expression of E-cadherin and the TNM stage of breast carcinoma,infiltration and lymph node metastasis(P=0.000;P=0.014;P=0.000).
     E-cadherin表达下调与乳癌TNM分期、浸润,淋巴结转移有关(P=0.000,P=0.014,P=0.000)。
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      breast carcinoma
    The role of β1 integrin subfamily in anchorage-dependent apoptosis of breast carcinoma cells differing in multidrug resistance
          
    The fusion protein was shown to be more potent in inhibiting the growth of cultured mouse breast carcinoma cells than interferon γ.
          
    We aimed to investigate the correlation between quantitative CerbB-2 expressions with conventional prognostic factors, and distinct nodal involvement in patients with invasive breast carcinoma.
          
    One hundred fifty seven consecutive breast carcinoma patients were retrospectively analysed.
          
    The left breast lumps were noted 4 months later, and she underwent a modified radical mastectomy under the impression of primary breast carcinoma.
          
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    During 1952-1958, 7 cases of primary malignant lymphomas of the breast were filed, an incidence of 0.22% of 3,247 primary malignant breast tumors seen during the same period. There were no definite clinical distinguishing features from breast carcinoma. Two cases were classified as diffuse lymphoblastic lymphosarcoma and one each as nodular prolymphocytic, nodular lymphoblastic, diffuse mixed cell type lymphosarcoma, Lennert's lymphoma, mixed cell type Hodgkin's disease. Treatments consisted of chemotherapy...

    During 1952-1958, 7 cases of primary malignant lymphomas of the breast were filed, an incidence of 0.22% of 3,247 primary malignant breast tumors seen during the same period. There were no definite clinical distinguishing features from breast carcinoma. Two cases were classified as diffuse lymphoblastic lymphosarcoma and one each as nodular prolymphocytic, nodular lymphoblastic, diffuse mixed cell type lymphosarcoma, Lennert's lymphoma, mixed cell type Hodgkin's disease. Treatments consisted of chemotherapy and Chinese herb drugs in 2 cases, radical mastectomies in 3, simple mastectomy and removal of the tumor mass each in 1. The latter 5 cases were treated with postoperative chemotherapy and radiotherapy. One nodular lymphoblastic lymphosarcoma lived 9 years after the operation. Another nodular prolymphocytic lymphosarcoma is still living and well 17 years postoperatively. The 5 other patients died after 7-15 months of treatments.

    我室在1952~1978年间收检7例乳腺原发恶性淋巴瘤,占同期乳腺原发性恶性肿瘤3,247例的0.22%。本瘤与乳腺癌临床上难鉴别。按组织学分型,弥漫性淋巴母细胞型2例和弥漫性混合细胞型淋巴肉瘤、结节性前淋巴细胞型、结节性淋巴母细胞型、Lennert氏淋巴瘤及混合细胞型何杰金氏病各1例。肿瘤活检后进行化疗和中药治疗2例,乳腺癌根治术3例、全乳切除及肿物切除各1例。后5例术后皆进行了放疗和化疗。结节性恶性淋巴瘤2例分别存活9年及17年。综合化疗和中药治疗1例,1年后健在。其余4例治疗后7~15月伤于本病。

    During 1954-1973 inclusive, 100 cases of medullary carcinoma were found among 2,063 cases of breast carcinoma at this hospital, an incidence of 4.3%. Based on their histopathologic and biologic characteristics, this series of medullary carcinoma is subdivided after Ridolfi into typical, atypical and non-specific types. Clinically, medullary carcinoma tends to occur in younger age group with lower incidence of axillary metastases and better prognosis. Radical mastectomy was carried out in most...

    During 1954-1973 inclusive, 100 cases of medullary carcinoma were found among 2,063 cases of breast carcinoma at this hospital, an incidence of 4.3%. Based on their histopathologic and biologic characteristics, this series of medullary carcinoma is subdivided after Ridolfi into typical, atypical and non-specific types. Clinically, medullary carcinoma tends to occur in younger age group with lower incidence of axillary metastases and better prognosis. Radical mastectomy was carried out in most of the cases. The 5-and 10-year survival rates were 78.5% and 79.2% respectively, the rates being 91.3% and 88.8% in typical types, 81.1% and 80% in atypical types, and 65.6% and 53.6% in non-specific types. Local recurrences occurred in 9.2% and 10.1% in 5-and 10-year groups, the corresponding figures were 4.3% and 0 in typical, 4.7% and 2.9% in atypical and 18.8% and 25% in non-specific types.

    我院1954——1973年间收治乳腺髓样癌100例,占同期全部乳腺癌2,063例的4.3%。髓样癌的病理诊断标准迄今尚不统一,作者根据其病理形态特点和生物特性,将其分为典型,不典型及非特殊型三种类型,(一) 典型髓样癌(24例)的癌细胞占癌组织的3/4以上,合体细胞占75%以上,细胞体大,圆形,椭圆形或多边形,核膜薄,核仁显著,核内染色质集中在核膜上,呈空泡状,细胞核分裂Ⅰ——Ⅱ级,癌组织呈膨胀性生长,边界较清楚,无腺管结构,但可能有微量管内癌成分,周固有大量淋巴细胞浸润,(二) 不典型髓样癌(44例)其特点一般同典型髓样癌,惟癌巢周围见有灶性或明显浸润,有不同量管内癌成分,可见少量腺管及乳头状结构、细胞核分级为Ⅲ级,周围有少或微量淋巴细胞浸润。(三) 非特殊型髓样癌(32例)的一般特点同不典型髓样癌、惟合体细胞成分少于75%而多于50%,伴有少量其他癌成分。髓样癌的发病年龄较轻,肿瘤体积较大,腋淋巴结转移较少,予后较好,本组病例治疗以乳癌根治术为主,其5及10年生存率分别为78.5%及72.2%,其中典型组分别为91.3%及88.8%,不典型组为81.1%及80%,非特殊型组为65.6%及53.6%。全组5...

    我院1954——1973年间收治乳腺髓样癌100例,占同期全部乳腺癌2,063例的4.3%。髓样癌的病理诊断标准迄今尚不统一,作者根据其病理形态特点和生物特性,将其分为典型,不典型及非特殊型三种类型,(一) 典型髓样癌(24例)的癌细胞占癌组织的3/4以上,合体细胞占75%以上,细胞体大,圆形,椭圆形或多边形,核膜薄,核仁显著,核内染色质集中在核膜上,呈空泡状,细胞核分裂Ⅰ——Ⅱ级,癌组织呈膨胀性生长,边界较清楚,无腺管结构,但可能有微量管内癌成分,周固有大量淋巴细胞浸润,(二) 不典型髓样癌(44例)其特点一般同典型髓样癌,惟癌巢周围见有灶性或明显浸润,有不同量管内癌成分,可见少量腺管及乳头状结构、细胞核分级为Ⅲ级,周围有少或微量淋巴细胞浸润。(三) 非特殊型髓样癌(32例)的一般特点同不典型髓样癌、惟合体细胞成分少于75%而多于50%,伴有少量其他癌成分。髓样癌的发病年龄较轻,肿瘤体积较大,腋淋巴结转移较少,予后较好,本组病例治疗以乳癌根治术为主,其5及10年生存率分别为78.5%及72.2%,其中典型组分别为91.3%及88.8%,不典型组为81.1%及80%,非特殊型组为65.6%及53.6%。全组5及10年局部复发率为9.2%及10.1%,其中典型组为4.3%及0,不典型组为4.7%及2.9%,非特殊型组为18.8%及25%。

    322 cases of intraductal breast carcinoma treated at Tianjin People's Tumor Hospital during 1953-1969 and followed up for 10 or more years were analysed. A positive relationship was not found between the patients' age, duration of the disease and size of the primary cancer and whether there Was infiltration or not. In noninfiltrative intraductal carcinomas none was with lymphnode involvement, and the 10 years survival rate was 100%. In infiltrative intraductal carcinomas, a positive correlation was found...

    322 cases of intraductal breast carcinoma treated at Tianjin People's Tumor Hospital during 1953-1969 and followed up for 10 or more years were analysed. A positive relationship was not found between the patients' age, duration of the disease and size of the primary cancer and whether there Was infiltration or not. In noninfiltrative intraductal carcinomas none was with lymphnode involvement, and the 10 years survival rate was 100%. In infiltrative intraductal carcinomas, a positive correlation was found in the frequency of lymphnode involvement and the extent of tumor infiltration. Sinee many of tae tumors without stromal infiltration were quite large in size, it does not seem to be logical to take the size as one of the important criteria in the staging system.

    本文对天津市人民医院1953~1969年乳癌根治术后,随访10年以上的322例非浸润性管内癌及浸润性管内癌的问质浸润程度与患者年龄、病期、原发瘤大小、淋巴结转移及存活期等关系进行了研究,并作了统计学处理。研究结果表明:非浸润管内癌与浸润性管内癌患者在年龄、病期及原发瘤大小等方面均无明显差异。在非浸润性管内癌组无淋巴结转移,10年生存率100%在浸润性管内癌组中,淋巴结转移数与间质浸润范围呈明显正相关,而存活期则与间质浸润范围呈明显负相关。由于相当部分非浸润性管内癌体积颇大,作者认为按原发瘤大小来判定乳癌期别不够确切。

     
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