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   susceptibility 在 感染性疾病及传染病 分类中 的翻译结果: 查询用时:0.196秒
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susceptibility     
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  易感性
    Conclusion: Plasma concentration of angiotensin Ⅱ is related to the progression of liver cirrhosis and the 1166A/C polymorphism of the AT1R gene is not related to hereditary susceptibility or progression of liver cirrhosis.
    结论:肝硬化患者血浆AngⅡ含量明显升高,并与肝硬化严重程度及门脉高压症的发生密切相关,AT1R 1166A/C基因多态性可能与乙肝肝硬化遗传易感性无关。
短句来源
    Association of HLA DRB1 allele and the susceptibility to alveolar echinococcosis in the west of China
    人白细胞抗原-DRB1等位基因与中国西部泡状棘球蚴病易感性的研究
短句来源
    A study on the association of 3′UTR polymorphisms of NRAMP1 gene with susceptibility to tuberculosis in Hans
    NRAMP1基因3′UTR多态现象与汉族结核病易感性的研究
短句来源
    A case-control study on the vitamin D receptor gene polymorphisms and susceptibility to pulmonary tuberclosis
    维生素D受体基因多态性与肺结核易感性的病例对照研究
短句来源
    A case-control study on natural-resistance-associated macrophage protein 1 gene polymorphisms and susceptibility to pulmonary tuberculosis
    自然抗性相关巨噬细胞蛋白1基因多态性与肺结核易感性的研究
短句来源
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    Methods From 76 clinical isolates of Mycobacterium tuberculosis,the routine culture and drug susceptibility detection were done by BACTEC-460 system,and the mutations of pncA gene detected by PCR-SSCP.
    方法应用BACTEC-460培养系统对76例结核分支杆菌临床分离株进行结核分支杆菌常规培养和药检测,聚合酶链反应-单链构象多态性(PCR-SSCP)技术检测pncA基因的突变。
短句来源
    Analysis of drug susceptibility for 256 strains of mycoplasma from NGU patients in Guangzhou
    广州地区NGU患者256株支原体药结果分析
短句来源
    The analysis of drug susceptibility results of 136 refractory tuberculosis
    136例慢性排菌肺结核临床药结果分析
短句来源
    Evaluation of the application for fast cultivation an d drug susceptibility tests by BACTEC-MGIT960 in diagnosis and treatment of patients with pulmonary tuberculosis
    BACTEC-MGIT960快速培养药对肺结核诊治的应用和评价
短句来源
    The bacterial strains' distribution and antimicrobiol susceptibility analysis of 111cases of tuberculosis accompanied with lower respiratory infection
    111例肺结核合并下呼吸道感染的菌种分布及药分析
短句来源
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  遗传易感性
    Conclusion: Plasma concentration of angiotensin Ⅱ is related to the progression of liver cirrhosis and the 1166A/C polymorphism of the AT1R gene is not related to hereditary susceptibility or progression of liver cirrhosis.
    结论:肝硬化患者血浆AngⅡ含量明显升高,并与肝硬化严重程度及门脉高压症的发生密切相关,AT1R 1166A/C基因多态性可能与乙肝肝硬化遗传易感性无关。
短句来源
    Genetic susceptibility to infectious diseases
    人类传染性疾病的遗传易感性
短句来源
    OBJECTIVE: ①To study the association between HLA-DR3、DR7、DR13、DR53 and HBV intrauterine infection, to probe into the susceptibility tointrauterine infection of hepatitis B virus and to find it’s predisposing genes andprotecting genes.
    目的 ①探讨 HLA-DR 等位基因 DR3、DR7、DR13、DR53 与 HBV 宫内感染的关系,探讨 HBV 宫内感染的遗传易感性,确定 HBV 宫内感染的易感基因和保护基因。
短句来源
    Conclusion Since CCR5 delta 32 mutation was not found,it can speculate that there may be a high genetic susceptibility for HIV-I in Guangxi Zhuang population of Guangxi region.
    结论由于未发现CCR5△32,推测广西壮族人群对HIV-1病毒感染可能具有较大的遗传易感性
短句来源
    This study suggests the possibility that IFN-γ gene polymorphism at position +874 may be important in determining an individual's susceptibility to development of chronic HBV infection.
    【结论】IFN-γ基因第一内含子+874位点多态性与慢性HBV感染有关,提示该位点多态性可能在决定个体HBV感染遗传易感性方面有一定意义。
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  感受性
    The results showed that there was no signifficant difference between both marmotas on susceptibility of sensitivity.
    结果表明,流行区和非流行区的旱獭对鼠疫的感受性和敏感性无明显差异;
短句来源

 

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      susceptibility
    The effect of the most promising ones have been looked on the counterparts from mammalian sources and difference in the susceptibility towards enzyme activity inhibition were noted.
          
    Direct current magnetic susceptibility measurement in the 2-300 K temperature range supports a high-spin ground state.
          
    The presence of a frequency-dependent alternating current susceptibility signal indicates that the individual molecule is acting as magnet.
          
    In addition, this method can simulate dispersive media whose electric susceptibility cannot be expressed with Debye or Lorentz types of models.
          
    Association of the genetic polymorphism of EPHX1 and EPHX2 with the susceptibility to chronic benzene poisoning
          
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    The tegumental surface antigens of different developmental stages of Schistosoma japonicum obtained from infected mice treated with a single oral dose of praziquantel 400mg/kg or artemether 600mg/kg were measured by indirected fluorescence assay. It was demonstrated that: (1) 4 hours after administration of praziquantel, the percentages of exposure of worm surface antigen were 90% in 2 hours' schistosomules (d0) and 25-42% in d21 to d42 schistosomules, but there was no effect on d3 to d14 old schistosomules;...

    The tegumental surface antigens of different developmental stages of Schistosoma japonicum obtained from infected mice treated with a single oral dose of praziquantel 400mg/kg or artemether 600mg/kg were measured by indirected fluorescence assay. It was demonstrated that: (1) 4 hours after administration of praziquantel, the percentages of exposure of worm surface antigen were 90% in 2 hours' schistosomules (d0) and 25-42% in d21 to d42 schistosomules, but there was no effect on d3 to d14 old schistosomules; 16 hours later over 50% of adult worms isolated from the liver tissue showed the exposure of worm surface antigen. It is considered that the susceptibility of different developmental stages of Schistosoma japonicum to praziquantel is correlated With the exposure of worm surface antigen. (2) 1 to 3 days after administration of artemether, marked disturbance of parenchymal tissue and intestinal tubes were found in d7 schistosomules, but there was no effect on the exposure of worm surface antigen. However, 33-42% of female worms in d28 group showed worm surface antigen. It is believed that the mode of action of artemether on young and adult schistosomes is different.

    应用间接荧光抗体法(IFA)检测不同发育期血吸虫体表抗原的显露情况表明,吡喹酮对小鼠体内2小时虫有90%出现明显的体表抗原显露;对3~14天虫的作用不明显;对从21~42天虫出现体表抗原显露的虫数逐渐增多,荧光强度亦有所增加。认为不同发育期血吸虫对吡喹酮敏感性的差异,与虫体体表抗原的显露有关。在小鼠体内的7天虫经蒿甲醚作用后,体表抗原显露不明显,但虫体实质组织和肠管均有明显的变化。28天虫出现体表抗原的虫数明显增多。认为蒿甲醚对童虫和成虫有着不同的杀虫机制。

    Mice harbouring different developmental stages of Schistosoma japonicum were treated orally with praziquantel at a single dose of 400 mg/kg and sacrificed 0.5-24 h after the medication for histological observation.After praziquantel treatment, the tegument of dc(3 h), d28, d35, and d42 schistosomes showed extensive vacuolation and rupture, while in d3, d7, d11, d14 and d21 schistosomules, little or only a mild local vacuolation of the tegument was detected. Strong host celt response was seen around the damaged...

    Mice harbouring different developmental stages of Schistosoma japonicum were treated orally with praziquantel at a single dose of 400 mg/kg and sacrificed 0.5-24 h after the medication for histological observation.After praziquantel treatment, the tegument of dc(3 h), d28, d35, and d42 schistosomes showed extensive vacuolation and rupture, while in d3, d7, d11, d14 and d21 schistosomules, little or only a mild local vacuolation of the tegument was detected. Strong host celt response was seen around the damaged d0, d28, d35 and d42 schistosomes, and the cells found were largely polymorphonuclear leucocytes. However, around d3-21 schistosomules, the cells were mainly lymphocytes and the host cell response was rather weak.The results confirmed that Schistosoma japonicum exhibited stage-specific susceptibility to praziquantel.

    应用组织病理学的方法。比较了各发育期日本血吸虫对吡喹酮作用的敏感性。结果表明:一次口服该药400mg/kg所引起的血吸虫皮层损害,以d_0(3h)童虫及d_(28~42)成虫为最严重;宿主的细胞反应也较强烈,并以中性粒细胞居多。而对d_(3~14)童虫则无或仅有轻微的皮层损害,宿主细胞反应亦较轻,且以淋巴细胞为主.d_(21)的童虫,虽有较为明显的皮层损害及宿主细胞反应,但细胞的类型与d_(3~14)童虫的相似.

    For investigating possible linkage between HLA system and gallstone disease, the frequency of HLA antigens in 28 patients with gallbladder stones (GBS) and 9 cases with bile duct stones (BDS) were studied and compared with a control group of 100 healthy subjects. A total of 54 antigens of HLA-A (15), -B (32), -C (7) and 17 antigens of locus DR were determined, using a standard lymphocyte microcytotoxicity assay. The percentage of the different antigens in pantients and in controls were compared by the chi-square...

    For investigating possible linkage between HLA system and gallstone disease, the frequency of HLA antigens in 28 patients with gallbladder stones (GBS) and 9 cases with bile duct stones (BDS) were studied and compared with a control group of 100 healthy subjects. A total of 54 antigens of HLA-A (15), -B (32), -C (7) and 17 antigens of locus DR were determined, using a standard lymphocyte microcytotoxicity assay. The percentage of the different antigens in pantients and in controls were compared by the chi-square test and the Fisher's p value were multiplied by the total number of antigens tested with the corrected p (Pc) value, less than 0.05 of which was considered significant.A significant increase of HLA-CW6, -DR1, -DR3, and -DRW8 was found in patients with gallstones with frequencies of 43.2%, 21.6%, 27% and 40.5% against 9%, 2%, 7% and 9% of controls with PC values 0.0008, 0.007, 0.045 and 0.0008 respectively, the relative risk (RR) value in gallstone group bsing 7.39, 11.35, 4.76 and 6.64.In further comparison of control group with GBS and BDS groups separately, a significantly high frequency of -CW6 and -DR1 was found in GBS group alone with the PC value of 0.0043 and 0.005, RR value of 7.3 and 13.74, whereas 6 of 9 patients in BDS group had antigen -DRW, which was significantly higher than that of the control group (66.7%, vs 9%) with PC value of 0.0027, RR value as high as 17.89. Antigen DR3 did not attain the desired level of significance either in GBS or BDS groups.Comparing with a Japanese report, our 8 patients with intrahepatic stones revealed a different phentype of HLA antigenes.This study has shown that: 1) in patients with gallstones there exists a disease susceptibility gene closely associated with the C and DR locus of the HLA system; 2) GBS and BDS groups reveal different linkage to HLA antigens and 3) in the same intrahepatic stone disease there exists ethnic variations.

    本文对37例胆石症病人作了HLA抗原测定并与100名健康人对照比较,发现胆石组HLA-CW_6、-DR_1、-DR_3及-DRW_8的分布频率分别为43.2%、21.6%、27%和40.5%.明显较对照组9%、2%、7%和9%的分布频率为高。其中-CW_6和-DR_1在胆囊结石组具有显著性;而-DRW_8抗原在胆管结石组中显著高于对照组。本组结果提示胆囊结石与胆管结石的易感基因可能存在于HLA不同的位点上。

     
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