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      n-methyl-d-aspartate
相关语句
  n-甲基-d-天门冬氨酸
    Roles Of N-methyl-D-aspartate and non-N-methy1-D-aspartate receptors in the respiratory rhythmical discharge of the hypoglossal nerve in the brainstem slice from neonatal rats
    N-甲基-D-天门冬氨酸和非N-甲基-D-天门冬氨酸类受体在新生大鼠延髓脑片呼吸节律性放电中的作用
短句来源
    Investigation of the gene expressions of N-methyl-D-aspartate(NMDA) receptors in visual cortex of cat
    猫视皮层N-甲基-D-天门冬氨酸受体的基因表达
短句来源
    Changes in Ca~(2+) concentration mediated by N-methyl-D-aspartate receptor in PO/AH neurons of anoxic SD rats
    N-甲基-D-天门冬氨酸受体介导缺氧SD大鼠PO/AH区神经元Ca~(2+)浓度的变化
短句来源
    Glutamate play both role in the physiology and pathology through its receptors, among them the N-methyl-D-aspartate (NMDA) has an important role within the process of learning and memory. At present, mostneuroscientists have approved the cell model of learning and memory-------Long-term potentiation (LTP) was based on the NMDA receptor.
    谷氨酸通过其受体发挥生理、病理等方面的作用,其中的N-甲基-D-天门冬氨酸(NMDA)受体更是在学习与记忆方面起着关键作用,目前被神经科学家所认同的学习记忆细胞模式——长时程增强(Long-term potentiation,LTP)的物质基础。
短句来源
    Objective To study the changes of Ca 2+ concentration mediated by N-methyl-D-aspartate (NMDA) receptor in the neurons in the preoptic area/anterior hypothalamus (PO/AH) of anoxic SD rats by investigating the properties of NMDA receptor.
    目的研究N-甲基-D-天门冬氨酸(NMDA)受体特性,探讨NMDA对缺氧大鼠PO/AH区神经元Ca2+浓度的影响。
短句来源
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  n-甲基-d-天门冬氨酸
    Roles Of N-methyl-D-aspartate and non-N-methy1-D-aspartate receptors in the respiratory rhythmical discharge of the hypoglossal nerve in the brainstem slice from neonatal rats
    N-甲基-D-天门冬氨酸和非N-甲基-D-天门冬氨酸类受体在新生大鼠延髓脑片呼吸节律性放电中的作用
短句来源
    Investigation of the gene expressions of N-methyl-D-aspartate(NMDA) receptors in visual cortex of cat
    猫视皮层N-甲基-D-天门冬氨酸受体的基因表达
短句来源
    Changes in Ca~(2+) concentration mediated by N-methyl-D-aspartate receptor in PO/AH neurons of anoxic SD rats
    N-甲基-D-天门冬氨酸受体介导缺氧SD大鼠PO/AH区神经元Ca~(2+)浓度的变化
短句来源
    Glutamate play both role in the physiology and pathology through its receptors, among them the N-methyl-D-aspartate (NMDA) has an important role within the process of learning and memory. At present, mostneuroscientists have approved the cell model of learning and memory-------Long-term potentiation (LTP) was based on the NMDA receptor.
    谷氨酸通过其受体发挥生理、病理等方面的作用,其中的N-甲基-D-天门冬氨酸(NMDA)受体更是在学习与记忆方面起着关键作用,目前被神经科学家所认同的学习记忆细胞模式——长时程增强(Long-term potentiation,LTP)的物质基础。
短句来源
    Objective To study the changes of Ca 2+ concentration mediated by N-methyl-D-aspartate (NMDA) receptor in the neurons in the preoptic area/anterior hypothalamus (PO/AH) of anoxic SD rats by investigating the properties of NMDA receptor.
    目的研究N-甲基-D-天门冬氨酸(NMDA)受体特性,探讨NMDA对缺氧大鼠PO/AH区神经元Ca2+浓度的影响。
短句来源
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  “n-methyl-d-aspartate”译为未确定词的双语例句
    Suppressive action produced by β-amyloid peptide fragment 31-35 on long-term potentiation in rat hippocampus is N-methyl-D-aspartate receptor independent:it’s offset by (-) huperzine A
    β-淀粉样蛋白31-35片段对大鼠海马长时程增强的抑制作用和(-)石杉碱A对此作用抵消(英文)
短句来源
    N-methyl-D-aspartate receptors (NMDARs) is one of ionotropic glutamatergic receptors.
    NMDAR(N-methyl-D-aspartate receptors,NMDAR)是中枢神经系统中离子型谷氨酸受体的一种类型,对Ca~(2+)有高通透性。
短句来源
    Two major subtypes of ionotropic glutamate receptors(GluRs), N-methyl-D-aspartate (NMDA)-type and a-amino-3-hydroxy-5-methyl-4- isoxazole-propionate( AMPA)-type receptors, are found localized on glutamatergic postsynaptic excitatory synapse. They fulfill coordinately the complex functional roles of glutamatergic neurotransmission.
    兴奋性突触突触后亲离子型谷氨酸受体主要是AMPA(α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate,AMPA)受体和NMDA(N-methyl-D-aspartate,NMDA)受体,二者协同完成兴奋性突触的传递和介导复杂的生理功能。
短句来源
    Objective To study the role of N-methyl-D-aspartate (NMDA) and non-NMDA receptors in the generation and modulation of basic respiratory rhythm.
    目的 探讨N-基-D-天门冬氨酸(N-methyl-D-aspartate,NMDA)和非NMDA类受体在基本呼吸节律发生和调 节中的作用。
短句来源
    Following micruinjection of ketamine (180 rnrnol/L, 0. lμl), a kind of N-methyl-D-aspartate (NMDA) receptor antagonist, SO motility was inhibited and the effect of glutamate was abolished.
    NRO内微巨注射 N-methyl-D-aspartate(NM-DA)受体阻断剂氯胺酮(180mmol/L,0.1μl),可消除谷氨酸的效应,而将微量非 NMDA受体阻断剂 CNQX(2mmol/L,0.1μl)注入NRO,可使奥迪氏括约肌肌电加强,且不能阻断谷氨酸的作用;
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  n-methyl-d-aspartate
The effects of intracerebroventricular (icv) agonists and antagonists of N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors on the general anesthesia of propofol were studied.
例句来源      
It has been demonstrated that the key target of these peptides are N-methyl-D-aspartate glutamate receptors.
例句来源      
Activation of rat cerebellum granule cells by N-methyl-D-aspartate (NMDA, 10-4-10-3 M) results in progressive increase in reactive oxygen species (ROS) and suppression of the ouabain-sensitive part of Na/K-ATPase activity.
例句来源      
Objective: To study the effect of glycine site/NMDA (N-methyl-D-aspartate) receptor antagonist MRZ2/576 on the conditioned place preference (CPP) and locomotor activity induced by morphine in mice.
例句来源      
Background and purpose A low-affinity, use-dependent N-Methyl-D-Aspartate (NMDA) antagonist AR-R15896AR has neuroprotective properties in animal models of ischaemic stroke.
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         The purpose of this study is to investigate the effect of microinjecti-on of 2-amino-5-phospho-novalerate (APV), N-methyl-D-aspartate(NMD-A) receptor antagonist, to the CA_3 region of the rat hippocampus on thesynaptic efficacy and relative conditioned behavior during establishmentof conditioned drinking response. The results showed that microinjection of APV caused significantlysuppression of the synaptic efficacy and the establishment of conditioneddrinking ...
            本文应用慢性埋植技术以电生理学结合行为学的方法,在大鼠条件性饮水反应的建立中,于每实验日训练开始前给海马CA_3区微量注射NMDA受体拮颃剂2-amino-5-phosphonovalerate(APV),观察它对海马CA_s区突触效应及与之相关的条件性行为反应的影响。发现注射APV后对CA_3区突触效应的习得性长时程增强的产生有显著的抑制性影响,相应地条件性饮水反应的建立也受到显著的抑制,提示NMDA受体参与习得性LTP的产主。
文摘来源
         The postsynaptic field potentials (PSPs) were recorded radially in the intermediate layers or deep layers respectively after stimulating the deep layers or intermediate layers of the Superior Colliculus in the brain slices of the rat. Long-term potentiation (LTP) was. for the first time, elicited in the deep division of the Superior Colliculus by the tetanic stimulation of 100Hz for 1s . The blocking effect of D, L-amino-5-phosphonovalerate (APV) . a selective antagonist for ##...
            在大白鼠上丘脑片深层部的中层或深层给电刺激、分别在径向对应的深层或中层,记录到诱发的突触后场电位.以100Hz、1秒的强直刺激首次在上丘的深层部引出了长时程突触增强(LTP).N-甲基-D-天冬氨酸(NMDA)受体的选择性拮抗剂2-氨基-5-磷酸戊酸盐(APV)对LTP的阻断效应表明,NMDA受体不仅对上丘深层部LTP的产生有作用.而且也与LTP的维持有关.突触后场电位的幅度受APV或兴奋性氨基酸受体的非选择性拮抗剂犬尿喹啉酸(KYNA)的作用而减小,受γ-氨基丁酸(GABA)A型受体的选择性拮抗剂荷包牡丹碱(Bicu)的作用而增加,表明谷氨酸能神经递质在上丘深层部的兴奋性突触传递中起着重要作用,并且这些突触传递也受到GABA能抑制性突触的调节.
文摘来源
         Excitutory postsynaptic potentials (EPSPs) and responses of neurons in the compact formation of the neucleus ambiguus (AMBc) to pressure-ejected or bath-applied test subetunces were recorded intracellularly from sagittul slices of Sprague-Dawley rat medulla containing subllucleus centralis of solitary complex (NTSc), AMBc and solitarioambigual pathway. In 5 cells, recorded spontaneous EPSPs could be blocked by morphine (3-5 pmol) to AMBc. Electrical stimulation of NTSc evoked E...
            在Sprayue-awiey大鼠的含有孤束核中央亚核及疑核神经元密集区的脑薄片上,吗啡(3—5pmol)对疑核细胞内记录到的自发兴奋性突触后电位有抑制作用;向灌流液内注入吗啡可使电刺激孤束核在疑核记录到的兴奋性突触后电位的幅度降低71.1±6.2%(P<O.001),纳洛酮(50mol/L)可翻转这种抑制效应;含有10μmol/L吗啡的灌流液对A(0.5—1pmol)、乙酰胆碱(3pmol)及QUisqualate(0.1—0.5pmol)引起的细胞膜去极化有不同程度的抑制作用,分别为38.1±5.7%(P<0.001),32.8±5.5%(P<0.01)和29.6±7.1%(P<0.05)。这些结果可能是由于吗啡兴奋μ和δ受体后,增加了K+电流而降低a+,Ca2+离子通透性的缘故。
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