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      n-methyl-d-aspartate
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  “n-methyl-d-aspartate”译为未确定词的双语例句
    Effect of acupuncture preconditioning on protein expression of N-methyl-D-aspartate receptor subunits NR2A and NR2B in parietal cortex during ischemia/reperfusion in rats
    针刺预处理对脑缺血再灌注大鼠顶皮质NR2A和NR2B蛋白表达的影响
短句来源
    (2) Expression level of nicotinic acetylcholine receptor(nACh-R) and glutamate N-methyl-D-aspartate receptor(NMDA-Rl) of cerebral cortex and hippocampus are assayed by immunohistochemical SABC method and computer pathological image analysis system.
    (2)提高N一乙酞胆碱受体及谷氨酸卜压。 A受体表达,改善神经元之间的信息传递,维护神经环路通讯联络。
短句来源
    Electro-acupuncture Affected NR2B Subunit of Hippocampus inRats with Learning and Memory Disfunction Induced by IschemiaObjective To prove the positive effects of electro-acupuncture(EA) on learning and memory ability in rats with acute cerebral ischemia-reperfusion repeatedly and to illustrate the effect of EA on N-methyl-D-aspartate receptor 2B subunit of the hippocampus in rats of learning and memory functional disturbance.
    目的 验证电针改善急性反复脑缺血再灌注大鼠学习记忆能力的有效性,阐述电针对缺血性学习记忆障碍大鼠NMDA受体NR2B亚单位的影响,初步探讨电针改善大脑学习记忆能力的作用机理。
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  n-methyl-d-aspartate
The effects of intracerebroventricular (icv) agonists and antagonists of N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors on the general anesthesia of propofol were studied.
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It has been demonstrated that the key target of these peptides are N-methyl-D-aspartate glutamate receptors.
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Activation of rat cerebellum granule cells by N-methyl-D-aspartate (NMDA, 10-4-10-3 M) results in progressive increase in reactive oxygen species (ROS) and suppression of the ouabain-sensitive part of Na/K-ATPase activity.
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Objective: To study the effect of glycine site/NMDA (N-methyl-D-aspartate) receptor antagonist MRZ2/576 on the conditioned place preference (CPP) and locomotor activity induced by morphine in mice.
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Background and purpose A low-affinity, use-dependent N-Methyl-D-Aspartate (NMDA) antagonist AR-R15896AR has neuroprotective properties in animal models of ischaemic stroke.
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         Objective Glutamate, acting at a spinal N-methyl-D-aspartate(NMDA) receptor has been implicated in development of central sensitization. The goal of the present study was to provide morphological evidences for the relation of NR1 to primary afferent C fiber in the spinal dorsal horn of the rat following inflammatory pain. Methods The Sprague-Dawley rats were divided into control group(n=12), inflammation group(n=12) and electroacu...
            目的 探讨在伤害性刺激条件下 ,初级感觉传入C纤维中枢突末梢上的NMDA受体NR1亚型蛋白(NMDAR1,NR1)的变化。 方法 对单侧佐剂性关节炎性痛模型 ,采用西非单叶豆同工凝集素 (BSI B4 )与NR1免疫荧光双标技术 ,观察致炎后不同时间段初级感觉传入突触前NR1的表达及其针刺后的变化。 结果 分别在各组大鼠的背根节和脊髓观察到BSI B4 NR1的双标产物。致炎后第 3d、7d各组大鼠致炎侧背根节中的双标神经元占各单标神经元的百分比关系为 :炎症组 (包括 3d、7d组 ) >电针组 (包括 3d、7d组 ) >生理盐水组 (包括 3d、7d组 ) (P <0 0 1) ;且炎症组和电针组大鼠均表现为 3d组 >7d组 (P <0 0 1)。 结论 提示脊髓后角突触前C纤维中枢突末梢上存在NR1,而且参与了单侧佐剂性关节炎大鼠痛觉过敏的形成 ;电针可能通过下调突触前的N$...
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         Objective To observe the influence of electroacupuncture(EA) on inflammatory pain,and elucidate the changes of Banderaea simplicifolia Isolectin B4(BSI-B4) binding sites and N-methyl-D-aspartate receptor one subunit(NMDAR-1) expression in the spinal cord following inflammatory pain.Methods In this study,we applied the complete Freunds′ adjuvant(CFA)-induced inflammatory pain model,the aim was to elucidate the overall progression of inflammation within 14 days after inject...
            目的观察电针对大鼠关节炎性痛的疗效并探讨其脊髓机制。方法采用大鼠单侧佐剂性关节炎性痛模型,对大鼠致炎后14 d内的痛反应情况作连续记录,且观察致炎后不同时间段(分别取第37、d)脊髓后角西非单叶豆同工凝集素(BSI-B4)结合位点和N-甲基-D-天冬氨酸受体NR1亚型蛋白(NMDA,NR1)的表达情况,以及在针刺条件下上述指标的变化情况。结果(1)电针后能明显改善炎性痛组大鼠的各痛反应指标变化(P<0.01),但仍未恢复到生理盐水组水平。(2)注射后第3、7 d各组大鼠(包括第37、d组)脊髓背角的BSI-B4结合位点和NR1表达关系比较如下:炎性痛组表达明显高于生理盐水组(P<0.01);经电针治疗后,电针组表达较炎性痛组减弱,但仍然比生理盐水组高(P<0.01);炎性痛组和电针组大鼠NR1的表达还表现为3 d组>7 d组(P<0.01)。结论电针可以明显改善单侧佐剂性关节炎大鼠各类痛反应指标,其可能机制是通过减缓炎性痛大鼠C伤害性感受器的持久发放,以及...
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