n-methyl-d-aspartate      n-甲基-d-天冬氨酸(98) n-甲基-d-天门冬氨酸(46) n-甲基-d-天门冬氨酸(0) n-甲基-d-天(47)   n-甲基-d-天冬氨酸     THE EFFECTS OF ZINC DEFICIENCY ON THE CONCENTRATION OF BRAIN FREE AMINO ACIDS AND SYNAPTIC MEMBRANES N-METHYL-D-ASPARTATE RECEPTORS IN RATS     缺锌对大鼠脑组织游离氨基酸和突触膜N-甲基-D-天冬氨酸受体含量的影响(英文) 短句来源     Relation between modulation of the N-methyl-D-aspartate receptor and cyanide-induced neurotoxicity     N-甲基-D-天冬氨酸型谷氨酸受体的调节与氰化物中枢毒作用 短句来源     Exercise and memory: Role of N-methyl-D-aspartate receptor and glutamic acid in learning and memory     运动与记忆:N-甲基-D-天冬氨酸受体和谷氨酸在学习记忆中的作用 短句来源     A major pathway leading to neuronal injury during cerebral ischemia/reperfusion (I/R) involves elevation of extracellular Glu and activation of N-methyl-D-aspartate receptor, with a subsequent calcium overload, resulting in activation of nitric oxide synthsae (NOS) and overproduction of free radicals, nitic oxide(NO) and peroxynitrite anion (ONOO-).     脑缺血/再灌注(ischemia/reperfusion, I/R) 损伤的主要通路就是细胞外谷氨酸水平升高→N-甲基-D-天冬氨酸（N-methyl-D-aspartate,NMDA）受体的过度激活→细胞内钙超载→一氧化氮合酶（nitric oxide synthase, NOS）激活→自由基、一氧化氮(nitric oxide, NO) 及过氧亚硝基阴离子（ONOO-）的大量产生。 短句来源     The p-tyr-pr immunoreactivity increase in the hippocampus induced by brain ischemia/reperfusion is related to N-methyl-D-aspartate receptor channel and L-type voltage gated calcium channel.     缺血 /再灌注后p -tyr-pr免疫反应性增强与N -甲基 -D -天冬氨酸 (NMDA)受体以及电压门控的钙离子通道有关 短句来源 更多          n-甲基-d-天门冬氨酸     Roles Of N-methyl-D-aspartate and non-N-methy1-D-aspartate receptors in the respiratory rhythmical discharge of the hypoglossal nerve in the brainstem slice from neonatal rats     N-甲基-D-天门冬氨酸和非N-甲基-D-天门冬氨酸类受体在新生大鼠延髓脑片呼吸节律性放电中的作用 短句来源     Investigation of the gene expressions of N-methyl-D-aspartate(NMDA) receptors in visual cortex of cat     猫视皮层N-甲基-D-天门冬氨酸受体的基因表达 短句来源     Changes in Ca~(2+) concentration mediated by N-methyl-D-aspartate receptor in PO/AH neurons of anoxic SD rats     N-甲基-D-天门冬氨酸受体介导缺氧SD大鼠PO/AH区神经元Ca~(2+)浓度的变化 短句来源     Comparison between seizures induced by N-methyl-D-Aspartate in Wistar rats and animal model of West syndrome     N-甲基-D-天门冬氨酸诱导Wistar乳鼠癫痫发作与West综合征动物模型的比较 短句来源     The mimic epitope of N-methyl-D-aspartate receptor 2B subunit screened from peptide library displayed on phage     噬菌体展示的肽库中N-甲基-D-天门冬氨酸受体2B亚基模拟抗原表位的筛选 短句来源 更多          n-甲基-d-天门冬氨酸     Roles Of N-methyl-D-aspartate and non-N-methy1-D-aspartate receptors in the respiratory rhythmical discharge of the hypoglossal nerve in the brainstem slice from neonatal rats     N-甲基-D-天门冬氨酸和非N-甲基-D-天门冬氨酸类受体在新生大鼠延髓脑片呼吸节律性放电中的作用 短句来源     Investigation of the gene expressions of N-methyl-D-aspartate(NMDA) receptors in visual cortex of cat     猫视皮层N-甲基-D-天门冬氨酸受体的基因表达 短句来源     Changes in Ca~(2+) concentration mediated by N-methyl-D-aspartate receptor in PO/AH neurons of anoxic SD rats     N-甲基-D-天门冬氨酸受体介导缺氧SD大鼠PO/AH区神经元Ca~(2+)浓度的变化 短句来源     Comparison between seizures induced by N-methyl-D-Aspartate in Wistar rats and animal model of West syndrome     N-甲基-D-天门冬氨酸诱导Wistar乳鼠癫痫发作与West综合征动物模型的比较 短句来源     The mimic epitope of N-methyl-D-aspartate receptor 2B subunit screened from peptide library displayed on phage     噬菌体展示的肽库中N-甲基-D-天门冬氨酸受体2B亚基模拟抗原表位的筛选 短句来源 更多          n-甲基-d-天     Roles Of N-methyl-D-aspartate and non-N-methy1-D-aspartate receptors in the respiratory rhythmical discharge of the hypoglossal nerve in the brainstem slice from neonatal rats     N-甲基-D-天门冬氨酸和非N-甲基-D-天门冬氨酸类受体在新生大鼠延髓脑片呼吸节律性放电中的作用 短句来源     Investigation of the gene expressions of N-methyl-D-aspartate(NMDA) receptors in visual cortex of cat     猫视皮层N-甲基-D-天门冬氨酸受体的基因表达 短句来源     Changes in Ca~(2+) concentration mediated by N-methyl-D-aspartate receptor in PO/AH neurons of anoxic SD rats     N-甲基-D-天门冬氨酸受体介导缺氧SD大鼠PO/AH区神经元Ca~(2+)浓度的变化 短句来源     Comparison between seizures induced by N-methyl-D-Aspartate in Wistar rats and animal model of West syndrome     N-甲基-D-天门冬氨酸诱导Wistar乳鼠癫痫发作与West综合征动物模型的比较 短句来源     The mimic epitope of N-methyl-D-aspartate receptor 2B subunit screened from peptide library displayed on phage     噬菌体展示的肽库中N-甲基-D-天门冬氨酸受体2B亚基模拟抗原表位的筛选 短句来源 更多            查询“n-methyl-d-aspartate”译词为其他词的双语例句   查询“n-methyl-d-aspartate”译词为用户自定义的双语例句     我想查看译文中含有：的双语例句 为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法，我们为您准备了出自英文原文的大量英语例句，供您参考。   n-methyl-d-aspartate The effects of intracerebroventricular (icv) agonists and antagonists of N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors on the general anesthesia of propofol were studied. 例句来源       It has been demonstrated that the key target of these peptides are N-methyl-D-aspartate glutamate receptors. 例句来源       Activation of rat cerebellum granule cells by N-methyl-D-aspartate (NMDA, 10-4-10-3 M) results in progressive increase in reactive oxygen species (ROS) and suppression of the ouabain-sensitive part of Na/K-ATPase activity. 例句来源       Objective: To study the effect of glycine site/NMDA (N-methyl-D-aspartate) receptor antagonist MRZ2/576 on the conditioned place preference (CPP) and locomotor activity induced by morphine in mice. 例句来源       Background and purpose A low-affinity, use-dependent N-Methyl-D-Aspartate (NMDA) antagonist AR-R15896AR has neuroprotective properties in animal models of ischaemic stroke. 例句来源       更多                    Nerve cells were cultivated from rat embryo cerebral cortices. On the 6th day in vitro, the cells were exposed to exogenous hypoxanthine (HPX, 1 mmol/L) and xanthine oxidase (XO, 0.78 u/ml). After 30 min the cells became swollen, broken and their intracellular potassium (Ki+) declined from 1.98 to 0.76 μmol/rng protein, indicating 62% loss of Ki+. The damage was less severe when shorter time or lower dose of XO was used. In the following experiment XO was used at a lower d$$...             在外源性次黄嘌呤和黄嘌呤氧化酶的作用下,培养神经细胞发生肿胀、破碎和K~+丢失等损伤性变化。当细胞外葡萄糖由5mmol/L降至2.5mmol/L及Ommol/L时,K~+丢失分别增加1.4倍及7.8倍。若同时加入谷氨酸盐1mmol/L或N-甲基-D-天冬氨酸(NMDA)0.4mmol/L,K~+丢失增高3倍。提高Mg~(2+)浓度至2.5mmol/L或加入DL-2-氨基-5-磷戊酸0.5mmol/L均可阻断谷氨酸盐对自由基损伤的增强作用。提示脑缺血,缺氧时,兴奋性氨基酸通过激动NMDA受体,使Ca~(2+)内流增加,从而加重自由基损伤。 文摘来源          Charactenstics of [3H]DL-glutamate(Glu) binding to human cerebral cortical membranepreparations were studied by a radiolabelled ligandbinding test. The optimum condition for the specificbinding of [3H]DL-Glu was established at 4℃HEPES buffer (pH 6.4-8.4) and 30-40 min forincubation. Extensive membrane washing before usewas a critical factor for the specific Glu binding. Thespecific binding was saturable through a singlehigh-affinity process with a KD of 103 nmol·L-1.a Bmax 1.67 nmol·...             用放射性配体受体结合实验研究了人大脑皮层膜与［３￣Ｈ］ＤＬ－谷氨酸结合的特性。人大脑皮层与谷氨酸特异性结合的最适条件是在４℃，ＨＥＰＥＳ缓冲液（ｐＨ６．４－８．６）中孵温３０－４０ｍｉｎ。结合实验前洗涤膜样品至为重要。人大脑皮层膜与谷氨酸特异性结合是可饱和的，其ＫＤ和Ｂｍａｘ值分别为１０３和１．６７ｎｍｏｌ·Ｌ－１蛋白，Ｈｉｌｌ系数１．０６．谷氨酸受体激动剂对人大脑皮层膜与谷氨酸结合的抑制强度依次为Ｌ－谷氨酸＞ＤＬ－谷氨酸＞红藻氨酸＞Ｎ－甲基－Ｄ－天冬氨酸（ＮＭＤＡ）＞Ｄ－谷氨酸。谷氨酸受体亚型拮抗剂２－氨基－５－磷酸基戊酸和６，７－二硝基唑喔啉－２，３－二酮（１ｎｍｏｌ·Ｌ－１）分别取代了５４％和５６％的特异性谷氨酸结合。１．２５ｎｍｏｌ·Ｌ－１镁离子抑制了５５％的特异性谷氨酸结合。人大脑皮层膜与谷氨酸的特异性结合不依赖钠离子，部分依赖于钙离子。人大脑皮层膜与谷氨酸特异性结合至少涉及到ＮＭＤＡ和红藻氨酸两个谷氨酸受体亚型。 文摘来源          Excitutory postsynaptic potentials (EPSPs) and responses of neurons in the compact formation of the neucleus ambiguus (AMBc) to pressure-ejected or bath-applied test subetunces were recorded intracellularly from sagittul slices of Sprague-Dawley rat medulla containing subllucleus centralis of solitary complex (NTSc), AMBc and solitarioambigual pathway. In 5 cells, recorded spontaneous EPSPs could be blocked by morphine (3-5 pmol) to AMBc. Electrical stimulation of NTSc evoked E...             在Ｓｐｒａｙｕｅ－Ｄａｗｉｅｙ大鼠的含有孤束核中央亚核及疑核神经元密集区的脑薄片上，吗啡（３—５ｐｍｏｌ）对疑核细胞内记录到的自发兴奋性突触后电位有抑制作用；向灌流液内注入吗啡可使电刺激孤束核在疑核记录到的兴奋性突触后电位的幅度降低７１．１±６．２％（Ｐ＜Ｏ．００１），纳洛酮（５０ｎｍｏｌ／Ｌ）可翻转这种抑制效应；含有１０μｍｏｌ／Ｌ吗啡的灌流液对ＮＭＤＡ（０．５—１ｐｍｏｌ）、乙酰胆碱（３ｐｍｏｌ）及ＱＵｉｓｑｕａｌａｔｅ（０．１—０．５ｐｍｏｌ）引起的细胞膜去极化有不同程度的抑制作用，分别为３８．１±５．７％（Ｐ＜０．００１），３２．８±５．５％（Ｐ＜０．０１）和２９．６±７．１％（Ｐ＜０．０５）。这些结果可能是由于吗啡兴奋μ和δ受体后，增加了Ｋ＋电流而降低Ｎａ＋，Ｃａ２＋离子通透性的缘故。 文摘来源   << 更多相关文摘         相关查询:  对查询结果不满意

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