n-methyl-d-aspartate n-甲基-d-天冬氨酸(98)   n-甲基-d-天冬氨酸     Effect of sodium gamma-hydroxybutyrate on expression of hippocampal N-methyl-D-aspartate receptor 2B subunit mRNA of hypoxic-ischemic neonatal rat     γ-羟丁酸钠对缺氧缺血后新生大鼠海马N-甲基-D-天冬氨酸受体2B亚基mRNA表达的影响 短句来源     Long-term expression of N-methyl-D-aspartate receptor in the hippocampus of neonatal rats with hypoxia-ischemic brain damage     N-甲基-D-天冬氨酸受体在缺氧缺血性脑损伤新生大鼠脑海马中的远期表达 短句来源     Objective To explore the expression of Fas pretein, N-methyl-D-aspartate(NMDA) receptor, the rate of neuronal apoptosis in the hippocampus under the hyperbilirubinemia and elucidate the molecular mechanism of bilirubin neurotoxicity.     目的 探讨高胆红素血症新生鼠海马区Fas蛋白、N-甲基-D-天冬氨酸(NMDA)受体的表达、神经细胞凋亡率及其间相关性，以进一步阐明胆红素的神经毒性机制。 短句来源     Objective To investigate the effects of magnesium sulfate on cultured rat hippocampal neuronal apoptasis induced by N-methyl-D-aspartate(NMDA).     目的研究硫酸镁对N-甲基-D-天冬氨酸(NMDA)诱导海马神经元凋亡的影响。 短句来源     Objective To explore the effect of maternal immunoglobulin G(IgG) on N-methyl-D-aspartate(NMDA) induced infantile spasms rat model and on the adrenocorticotrophic hormone(ACTH) expression in brain.     目的探讨母体免疫球蛋白G(IgG)对N-甲基-D-天冬氨酸(NMDA)诱导婴儿痉挛大鼠模型的临床作用及其对脑内促肾上腺皮质激素(ACTH)免疫反应阳性细胞表达影响。 短句来源 更多          “n-methyl-d-aspartate”译为未确定词的双语例句     Effects of sodium hydroxybutyrate on expression of hippocampal N-methyl-D-aspartate receptor 2A subunit mRNA in hypoxic-ischemic neonatal rat     羟丁酸钠对缺氧缺血后新生大鼠海马NMDA受体2A亚基的影响 短句来源     Effects of Sodium hydroxybutyrate on expression of hippocampal N-methyl-D-aspartate receptor 1 subunit mRNA in neonatal rat with hypoxic-ischemic insult     缺血缺氧后新生大鼠海马NR1-mRNA表达的变化及羟丁酸钠对其的影响 短句来源 查询“n-methyl-d-aspartate”译词为用户自定义的双语例句     我想查看译文中含有：的双语例句 为了更好的帮助您理解掌握查询词或其译词在地道英语中的实际用法，我们为您准备了出自英文原文的大量英语例句，供您参考。   n-methyl-d-aspartate The effects of intracerebroventricular (icv) agonists and antagonists of N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors on the general anesthesia of propofol were studied. 例句来源       It has been demonstrated that the key target of these peptides are N-methyl-D-aspartate glutamate receptors. 例句来源       Activation of rat cerebellum granule cells by N-methyl-D-aspartate (NMDA, 10-4-10-3 M) results in progressive increase in reactive oxygen species (ROS) and suppression of the ouabain-sensitive part of Na/K-ATPase activity. 例句来源       Objective: To study the effect of glycine site/NMDA (N-methyl-D-aspartate) receptor antagonist MRZ2/576 on the conditioned place preference (CPP) and locomotor activity induced by morphine in mice. 例句来源       Background and purpose A low-affinity, use-dependent N-Methyl-D-Aspartate (NMDA) antagonist AR-R15896AR has neuroprotective properties in animal models of ischaemic stroke. 例句来源       更多                    Objective To explore the effect of bilirubin on intracellular Ca 2+ of cerebral cortex neurons and the therapeutic effect of MgSO 4. Methods Cerebral cortical neurons were cultured from the embryonic rat brain. The free cytosolic Ca 2+ concentration ([Ca 2+ ]i) of the cultured neurons was determined with a fluorescent Ca 2+ chelator (Fura-2) after exposure of the neurons to different concentrations of bilirubin. Results Immature neurons (n$...             目的　探讨胆红素诱导原代培养神经细胞内Ca2 + 含量的变化 ,以及MgSO4 的拮抗作用。方法　采用胎鼠大脑皮层细胞作原代神经细胞培养 ,观察 10 0 μmol/L胆红素对不同成熟程度神经细胞内Ca2 + 含量的影响。原代培养神经细胞经Fura- 2 /AM负载 ,荧光图像分析测定细胞内Ca2 + 含量。结果　未成熟神经细胞 (培养2天 )暴露于 10 0 μmol/L胆红素 4h ,细胞内Ca2 + 从 75 .3nmol增加到 32 0 .8nmol;继续暴露 4h ,细胞内Ca2 + 增加到 40 0 .7nmol;去除胆红素暴露 ,细胞内Ca2 + 不能逆转。成熟神经细胞 (培养 8天 )暴露于 10 0 μmol/L胆红素 4h ,细胞内Ca2 + 从 70 .6nmol增加到 15 0 .8nmol;继续暴露 4h ,细胞内Ca2 + 不再增加 ;去除胆红素暴露 ,细胞内Ca2 + 浓度可显著降低。培养液中Mg2 + 加至 2mmol/L可减轻胆红素诱导的神经细胞内Ca2 + 含量变化。结论　胆红素可诱导原代培养的、未成熟的神经细胞C... 文摘来源          In order to explore the neuroprotective effect of Memantine against hypoxic ischemic (HI) invasion, Memantine was intraperitoneally injected at a dose of 20 mg/kg in neonatal rat models either before (PRE group) or after (POST group) cerebral hypoxic ischemia (HI), and its neuroprotective effect was evaluated by detecting the change of HSP70 gene expression. The results showed that HSP70 mRNA expression decreased significantly after Memantine administration in both of PR...             近来报道非竞争性NMDA受体拮抗剂美金胺 (Memantine)对缺氧缺血损伤 (HI)具有脑保护作用。在对HI新生大鼠先行进行了HSP70基因表达的研究基础上 ,对新生大鼠在HI前后对照应用美金胺 ,通过观察HSP70基因表达的变化 ,进一步从分子水平评估美金胺的脑保护效果。结果显示 ,HSP70mRNA在正常情况下仅有极微弱表达 ,HI后可引起其表达明显增加。应用美金胺后 ,其HSP70基因表达虽较正常对照组增高 ,但显著弱于HI组 ,提示美金胺的应用具有一定的脑保护作用 ,可能减轻了HI的脑损伤 ,因而使作为一种敏感的脑缺氧缺血标志的HSP70基因的表达降低。数据显示美金胺在HI前应用较之HI后应用似有更明显的脑保护效果 ,尽管统计显示其差异无显著性意义。结合已完成的脑病理研究和病理量化评分 ,初步证实美金胺作为较安全有效的NMDA受体离子通道非竞争性拮抗剂 ,对由NMDA受体所介导的神经兴奋毒作用有一定疗效 文摘来源          Objective To observe the changes of the N methyl D aspartate receptor expression in cerebral cortex of piglet models, undergone cardiopulmonary bypass surgery of hypothermic low flow status(DHLF)and to investigate the possible mechanism of the cerebral insult after DHLF. Methods Eighteen piglets were divided into three groups: the control group and the other two groups with a flow of 25 ml·min -1 ·kg -1 and 5 ml·min -1 ·kg -1 ,respectively .T...             目的　观察乳猪深低温下不同程度低流量转流前后大脑皮层N 甲基 D 天冬氨酸 (NMDA)受体表达的变化 ,探讨深低温下不同流量转流后脑损害发生的可能机制。方法　取 3～ 4周龄乳猪 18头 ,随机均分为对照组、2 5ml·min-1·kg-1流量组和 5ml·min-1·kg-1流量组。分别于转流前 ,深低温低流量转流 1h后及复温至肛温 (36°C)再常温转流 2h后 (C点 ) ,经颅底钻孔取大脑皮质 ,用RT PCR法观察皮质NMDA受体表达的变化。结果　在 5ml·min-1·kg-1流量组C点时NMDA受体表达与对照组及该组起始值比较呈显著升高 ,而 2 5ml·min-1·kg-1流量组转流后与转流前该受体表达的差异无显著性。结论　深低温时过低流量转流后可引起大脑皮质NMDA受体表达升高 ,从而引起继发性脑损害 文摘来源   << 更多相关文摘         相关查询:  对查询结果不满意

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