RESULTS: ① The plasma levels of ET, TNF, ALT, AMY, BUN, CK in both penicillin sodium group and control group were increased significantly after craniocerebral explosive injury (P<0.05); however, the plasma levels of ET, TNT, ALT, AMY, BUN, CK in the former group were lower than the latter from 24 h after craniocerebral explosive injury (P<0.01);
Our studies demonstrated an in vivo cardioprotection effect of (N-(3,4,-dimethoxy-2-chlorobenzylideneamino)-guanidine: ME10092) in ischaemic reperfusion injury in the rodent.
Diclofenac (25 mg kg-1) and meloxicam (7.5 mg kg-1) produced 9.3 and 19.6 mm2 ulcer areas in stomachs of rats, respectively, when used alone, but when combined with nimesulide diclofenac and meloxicam did not cause any injury in rat stomachs.
These proteins may be involved in cardiovascular injury, and could play an important role in the treatment of coronary heart disease.
SOD and POD activities declined correspondingly, followed by significant increases of MDA and MP, and leaf injury was finally observed.
Hepatocellular injury was the predominant type in these cases (132 cases, 48%).