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breast tumor     
相关语句
  乳腺肿瘤
     Results:(1)The expression of CD 44V6 in breast cancer was significantly higher than that in benign breast tumor.
     结果 :CD44 S、CD44 V3 表达在乳腺癌和良性乳腺肿瘤组织中无显著差异 ,CD44 V6 表达在乳腺癌组织明显高于良性组织 ;
短句来源
     Preliminary Clinical Study on Distinguishing Breast Tumor with~(99)Tc~m-HL91 Imaging
     ~(99)Tc~m-HL91显像鉴别乳腺肿瘤良恶性的初步临床研究
短句来源
     Result: 1. The expression level of LPA1 was significantly higher in breast cancer tissue than in benign breast tumor tissue (P<0.05) and in normal lacteal gland tissue (P<0.05).
     结果: 1.LPA1在乳腺癌组织中的表达水平显著高于良性乳腺肿瘤组织(P<0.05)和正常乳腺组织(P<0.05),乳腺癌最大直径≥2cm组显著高于直径<2cm组(P<0.05),浸润性导管癌显著高于其它浸润性乳腺癌(P<0.05);
短句来源
     Differential Diagnostic Value of Combined Detection of Serum CA153,CEA and TPA Levels in Patients with Breast Tumor
     血清CA153、CEA和TPA联检在术前乳腺肿瘤鉴别诊断中的价值
短句来源
     Overexperession of c-erbB-2 Oncogene of Breast Tumor in Rat
     C-erbB-2癌基因在大鼠乳腺肿瘤中的异常表达
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  乳腺肿块
     Results FNAC has different accuracy on the diagnosis of different breast tumor. The total sensitivity was 97.1%,and specificity was 98.5%,and the total correspondence rate was 97.6%,and the rate of misdiagnosis was 2.4%.
     结果针吸细胞学对不同类型乳腺肿块诊断准确率不同,总敏感性97.1%,特异性98.5%,总准确率97.6%,总误诊率2.4%。
短句来源
     Diagnostic value of ~(99m)Tc-MIBI breast tumor and axillary lymph node imaging
     ~(99m)Tc-MIBI显像对乳腺肿块及腋淋巴结的诊断价值
短句来源
     We set the CDFI density quantitative value>3.62,which was the mean value of benign breast tumor,as the diagnosis standard to verdict malignant tumor. Its accuracy was76.0%,specificity was83.8%and sensitivity was53.8%,which was higher than CDFI level method.
     以CDFI密度量化值大于3.62(良性乳腺肿块的CDFI密度量化平均值)作为乳腺恶性肿块的诊断标准:准确性76.0%,特异度83.8%,灵敏度53.8%,均高于CDFI等级法。
短句来源
     The ultrasound diagnostic analysis of breast tumor of 89 cases
     超声诊断乳腺肿块89例分析
短句来源
     Pathological Analysis of 298 Cases of Breast Tumor
     298例乳腺肿块临床病理分析
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  乳房肿瘤
     Results:In 313 children there were 78 children with hyperplasia of the breast image, and 4 children with breast tumor.
     结果  313例中 ,发现 78例乳腺增生 ,4例乳房肿瘤
短句来源
     Results 9 cases were treated by amplification exicision of breast tumor,4 cases by mastectomy and 2 cases by nodified radical mastectomy,and 7 cases local excision of breast tumor were made,among which 4 local excision of breast tumor was found recurrent.
     结果 行乳房肿瘤扩大切除术 9例 ,乳房切除术 4例 ,乳房改良根治术 2例 ,行乳房肿瘤局部切除术 7例。
短句来源
     The Immunity Assay and its Clinical Significance in Patients with Breast Tumor
     乳房肿瘤患者免疫功能检测及其临床意义
短句来源
     A Study on the Aesthetic Incision at Excision Benign Breast Tumor
     应用美乳切口实施乳房肿瘤切除的研究
短句来源
     According to distance discriminant analysis method and the empirical data, the author establishes one kind of method to diagnose whether breast tumor is benign or malignant.
     本文根据已获得的实验数据,运用多元统计中的距离判别分析方法,建立起一种诊断乳房肿瘤是良性还是恶性的方法。
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  乳腺肿瘤的
     Breast tumor malignant degree increased with Cx43and Cx26 0291positive expression decreased.
     随着Cx43和Cx26的阳性表达率降低,乳腺肿瘤的恶性程度增高。
短句来源
     With the development of MRI techniques and the clinical application of fast imaging, diagnosis of breast tumor arrives a higher level.
     近20年来随着磁共振成像技术的发展,MRI的快速成像序列相继应用于临床研究,对乳腺肿瘤的诊断水平达到了一个新的高度。
短句来源
     Out of 43 Cx43 positive staining, 31(72.09%) were observed in moderately and well-differentiated tumors (I-II graded). Breast tumor malignant degree increased with Cx43 positive expression decreased (P<0.05).
     43例Cx43阳性患者中,I-II级的31例(72.09%),随着Cx43阳性表达率降低,乳腺肿瘤的恶性程度增高(P<0.01)。
短句来源
     The Values of Sonography and Ultrasound Contrast in the Breast Tumor
     超声对乳腺肿瘤的鉴别诊断和乳腺肿瘤的超声造影灌注研究
短句来源
     Breast Tumor Imaging Method Investigation in UWB Near-field Environment
     UWB近场环境下乳腺肿瘤的成像方法研究
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      breast tumor
    MUC1 mucin is a carrier of this carbohydrate antigen, CA19-9, or sialyl-Lewisa, as well as of CA15-3 antigen, a known breast tumor marker.
          
    The results suggest that changes in decorin, lumican, and syndecan-1 expession in tumor tissue could induce a distortion of proteoglycan composition and mitotic activity of cells in human breast tumor.
          
    We hypothesize that low-activity alleles SULT1A1*2 and UGT1A1*28 are associated with higher risk for breast cancer and more severe breast tumor phenotypes.
          
    injection indicate the accumulation of [99mTc]-2 in MCF-7 human breast tumor bearing mice at 20 h.
          
    This indicates that CDK4 plays an important role in formation and development of breast tumor.
          
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    From February 1978 to July 1080, 2,000 patients with breast tumor were examined by fine needle aspiration technique. Diagnosis in 1,024 of these cases was established histopathologically; cytological diagnosis was correct in 87.4% of this group. This technique is simple, easily performed with fairly high rate of success, and may be used in mass screening for breast cancer.

    (1) 1978年2月—1980年7月共行乳腺肿块细针穿刺细胞学检查2,000例。其中有病理确诊1,024例,细胞学诊断符合率为87.4%。(2) 此法简便易行,不需特殊设备,确诊率较高,可作为术前诊断的参考依据,亦适用于普查筛选。(3) 细胞学诊断失败主因为取材不佳,细胞量太少,染色欠佳,细胞形态不典型及阅片时未全面分析等。

    Inclusion of sodium molybdate(Mo)in the buffer could stabilize the steroid bindingactivity,inhibit the degradation and minimize the structural heterogenicity of receptors.Effects of M_0 on human breast tumor and benign and malignant endometrial cytosol es-trogen(ER)and progesterone receptors(PR)were studied by glycerol gradient centrifuga-tion and chromatographed on agarose in buffers containing 20 mMM_0.The sedimenta-tion coefficients(S_(20,w))of the receptors were evaluated by glycerol gradient centrifuga-tion...

    Inclusion of sodium molybdate(Mo)in the buffer could stabilize the steroid bindingactivity,inhibit the degradation and minimize the structural heterogenicity of receptors.Effects of M_0 on human breast tumor and benign and malignant endometrial cytosol es-trogen(ER)and progesterone receptors(PR)were studied by glycerol gradient centrifuga-tion and chromatographed on agarose in buffers containing 20 mMM_0.The sedimenta-tion coefficients(S_(20,w))of the receptors were evaluated by glycerol gradient centrifuga-tion and the mean value was 9.7±0.3S(n=31).The stoke radii(R_s)were distinguishedby gel filtration and the mean value was 75±4(?)(n=22).The molecular weight(M)and axial ratio(a/b)of the receptors were calculated by combining the data from ultra-centrifuged and gel filtration analysis and the mean values of M=304,000,and a/b=10.The concentration of ER and PR were determined by charcoal-dextron assay follow-ing incubation of cytosols with various concentrations of [~3H]E_2 or [~3H] R 5020 in bufferscontaining 20 mMMo from 47 cases of human breast cancer,10 malignant endometriumand 10 benign endometrium.The ER and PR (>3 fmol/mg protein)finds in the breasttumor specimens were 48% and 72%,respectively.90% of malignant uterine speci-mens contained PR,and 100% of benign endometrium with ER and PR.The concent-tration of PR was the highest,458±275 fmol/mg protein,in benign endometrial samplesfrom premenopausal women.Dissociation constants(Kd)were evaluated from 24 speci-mens.The mean value for Kd of [~3H] E_2 binding to cytosol from breast cancer was 0.4 nMand that for Kd of [~3H] R 5020 binding to cytosol from both breast and uterine malignanttumors was 2-3 nM.

    钼酸钠(M_0)能稳定受体对甾体的结合活力、并抑制其降解和减少其结构的多相性。在有M_0存在的缓冲系统中,通过对人类乳腺癌、良性和恶性的子宫内膜细胞溶质雌激素受体(ER)和孕激素受体(PR)进行梯度超离心和琼脂糖凝胶过滤的研究,得到的结果为:受体的沉降系数(S_(20,w))的平均值为9.7±0.3S(n=31),其流体力学半径(R_(?))的平均值为75±4(?)(n=22);综合超离心和凝胶过滤的分析资料计算得到,M_0稳定时受体分子量(M)的平均值为304,000,轴比(a/b)=10。本文报告了47例人乳腺肿瘤、10例恶性子宫内膜、10例良性子宫内膜的细胞溶质ER 和PR 的浓度及受体阳性、阴性及可疑的分布。乳腺肿瘤的ER 阳性率为48%,PR 阳性率为72%(>3fmol/mg 蛋白为阳性),90%恶性子宫内膜的PR 为阳性;100%良性子宫内膜的ER 或PR 均为阳性。绝经前妇女的良性子宫内膜的PR 浓度最高,为458±275fmol/mg 蛋白。对24例标本均测定了解离常数(K_d),其中乳腺和恶性子宫内膜组织中PR-[~3H]R5020复合物的K_d 平均值为2-3nM,乳腺癌组织中ER-[~...

    钼酸钠(M_0)能稳定受体对甾体的结合活力、并抑制其降解和减少其结构的多相性。在有M_0存在的缓冲系统中,通过对人类乳腺癌、良性和恶性的子宫内膜细胞溶质雌激素受体(ER)和孕激素受体(PR)进行梯度超离心和琼脂糖凝胶过滤的研究,得到的结果为:受体的沉降系数(S_(20,w))的平均值为9.7±0.3S(n=31),其流体力学半径(R_(?))的平均值为75±4(?)(n=22);综合超离心和凝胶过滤的分析资料计算得到,M_0稳定时受体分子量(M)的平均值为304,000,轴比(a/b)=10。本文报告了47例人乳腺肿瘤、10例恶性子宫内膜、10例良性子宫内膜的细胞溶质ER 和PR 的浓度及受体阳性、阴性及可疑的分布。乳腺肿瘤的ER 阳性率为48%,PR 阳性率为72%(>3fmol/mg 蛋白为阳性),90%恶性子宫内膜的PR 为阳性;100%良性子宫内膜的ER 或PR 均为阳性。绝经前妇女的良性子宫内膜的PR 浓度最高,为458±275fmol/mg 蛋白。对24例标本均测定了解离常数(K_d),其中乳腺和恶性子宫内膜组织中PR-[~3H]R5020复合物的K_d 平均值为2-3nM,乳腺癌组织中ER-[~3H]E_2复合物的K_d 平均值为0.4nM。

    Glucose-6-phosphate dehydrogenase (G6PD) is an estrogen-mediated enzyme, In human breast carcinoma, the level of G6PD activity usually is correlated with the concentartion of estradiol receptors (ER). G6PD activity and isoenzyme pattern are measured in ten samples of breast carcinoma and normal mammary tissue and one sampleof benign breast tumor. It is found that G6PD activity is much higher in carcinoma and less higher in benign tumor than in normal mammary tissue. G6PD isoenzyme pattern is found...

    Glucose-6-phosphate dehydrogenase (G6PD) is an estrogen-mediated enzyme, In human breast carcinoma, the level of G6PD activity usually is correlated with the concentartion of estradiol receptors (ER). G6PD activity and isoenzyme pattern are measured in ten samples of breast carcinoma and normal mammary tissue and one sampleof benign breast tumor. It is found that G6PD activity is much higher in carcinoma and less higher in benign tumor than in normal mammary tissue. G6PD isoenzyme pattern is found to be similar in both carcinoma and normal mammary tissue. G6PD activity varies greatly in different samples of carcinoma, but it may be used as an auxiliary marker in patients receiving endocrine therapy.

    6-磷酸葡萄糖脱氢酶(G6PD)是一个雌激素诱导酶,人乳腺癌较高雌激素受体水平与较高G6PD活性有关。本组对10例乳腺癌标本及正常乳腺组织和1例良性乳腺肿瘤测定其G6PD活性及同工酶谱,结果癌组织的G6PD活性显著地高于正常组织。癌组织与正常乳腺组织之间G6PD同工酶谱无差别。癌组织标本之间G6PD活性相差很大,这可能与雌激素受体存在与否有关。一般实验室测雌激素受体尚有困难,测定乳腺癌标本的G6PD活性能否作为乳腺癌患者内分泌治疗的一种辅助指标,尚有待与雌激素受体同时测定进行研究。

     
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