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消化系统疾病
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ulcer     
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  溃疡
    Experimental Studies on the Relationship between Endothelin-1 Gene and Stress Ulcer
    内皮素-1基因表达与应激性溃疡关系的实验研究
短句来源
    Analysis On 826 Cases With Peptic Ulcer Wnder Fibergastroscope
    826例消化性溃疡纤维胃镜检查分析
短句来源
    CHANGES OF MUCOSAL BLOOD FLOW IN THE HEALING PROCESS OF PEPTIC ULCER
    消化性溃疡愈合过程中粘膜血流量的变化
短句来源
    Pirenzepine in short term clinical trial of peptic ulcer in 23 patients
    哌仑西平短程治疗消化性溃疡23例
短句来源
    Analysis of 5272 Cases of Peptic Ulcer with Gastroscopy
    纤维胃镜检查5272例消化性溃疡分析
短句来源
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  溃疡的
    Medical Treatment of Peptic Ulcer
    消化性溃疡的内科治疗
短句来源
    Therapeutic Value of Tripotassium Dicitratobismuthate in Duodenal Ulcer—Report of 76 Cases
    三钾双枸橼酸铋对十二指肠溃疡的治疗价值—附76例报告
短句来源
    Immediatly Results of Contraceptive No. 2 on Peptic Ulcer
    避孕2号对消化性溃疡的疗效
短句来源
    Clinical and Endoscopic Features of Asymptomatic Peptic Ulcer:An Analysis of 126 Cases
    无症状消化性溃疡的临床与内镜特点(附126例病例分析)
短句来源
    Omeprazole for peptic ulcer in 65 patients
    奥美拉唑对65例消化性溃疡的疗效
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  胃溃疡
    Effect of Selective COX-2 Inhibitor on the Healing of Experimental Rat Gastric Ulcer
    选择性COX-2抑制剂对实验性大鼠胃溃疡愈合的影响
短句来源
    Effect of hTFF2 Gene Therapy on the Healing of Experimental Gastric Ulcer in Rats
    人三叶因子2基因治疗对实验性大鼠胃溃疡愈合的影响
短句来源
    An Analysis of Gastroscopy Clinic Pathology and Operation (50 Cases) in 153 Cases of Gastric Ulcer after Fifty Years Old
    50岁以上胃溃疡153例胃镜检查与临床病理及手术(50例)结果分析
短句来源
    Study on the volume of gastric mucosal blood flow and change of acid secretion in rats with gastric ulcer
    胃溃疡大鼠胃粘膜血流量与泌酸变化的研究
短句来源
    IMMUNOELECTRON MICROSCOPIC STUDY ON ACTH CELLS IN PARS DISTALIS OF RAT PITUITARY DURING HEALING COURSE OF EXPERIMENTAL GASTRIC ULCER
    大鼠实验性胃溃疡自愈期间垂体远侧部ACTH细胞的免疫电镜研究
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  溃疡病
    Cimetidine Made in China in the Treatment of Peptic Ulcer: Clinical Observation of 101 Cases
    国产甲氰咪胍治疗溃疡病101例临床观察
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    The function of gastric acid secretion in gastritis and peptic ulcer: an analysis of the results of pentagastrin method in 348 cases
    348例胃炎及溃疡病患者的五肽胃泌素法结果分析
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    A Case—control Study of Gastric and Duodenal Ulcer
    胃、十二指肠溃疡病例对照研究
短句来源
    Study of the Function of Pituitary-Thyroid Axis in Patients with Peptic Ulcer, Hepatocirrhosis and Hepatocellular Carcinoma
    溃疡病、肝硬化和肝癌患者垂体—甲状腺功能的研究
短句来源
    Discussions on the Clinical Investigation of TCM Treatment for Hemorrhage of Peptic Ulcer
    中医药治疗溃疡病出血临床研究若干问题探讨
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      ulcer
    Diclofenac (25 mg kg-1) and meloxicam (7.5 mg kg-1) produced 9.3 and 19.6 mm2 ulcer areas in stomachs of rats, respectively, when used alone, but when combined with nimesulide diclofenac and meloxicam did not cause any injury in rat stomachs.
          
    While ranitidine at 100 mg kg-1 dose prevented diclofenac-induced ulcer formation, it reduced meloxicam-induced ulcer formation significantly.
          
    Antiulcer Effects of the Tripeptide PGP and Its Possible Metabolites (PG, GP, Glycine, and Proline) in Different Models of Ulcer
          
    PG reduced the ethanol- and indomethacin-induced lesions approximately twofold but was considerably less effective in stress-induced ulcer.
          
    GP decreased the stress- and indometacin-induced ulcer but tended to stimulate the ethanol-induced lesions.
          
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    In this study, we have analyscd 380 endoscopies canied out on patients with upper gastrolntestinal bleeding. Positive diagnosis was fouud in 341 of all patients (89.7%). Peptic ulcer disease comprised the largest group (43.4%). The incidence of various gastritis, tumor and oesophageal varices respectively was 24.4%, 11.60% and 3.68% Actively bleeding and rescently bleeding lesions wcre found in 87 of all patients. Among these 87 patiens it has been shown that a detection rate of 55.56% within 48 hours...

    In this study, we have analyscd 380 endoscopies canied out on patients with upper gastrolntestinal bleeding. Positive diagnosis was fouud in 341 of all patients (89.7%). Peptic ulcer disease comprised the largest group (43.4%). The incidence of various gastritis, tumor and oesophageal varices respectively was 24.4%, 11.60% and 3.68% Actively bleeding and rescently bleeding lesions wcre found in 87 of all patients. Among these 87 patiens it has been shown that a detection rate of 55.56% within 48 hours of bleeding falls to 18% after 48 hours. The diagnosis of endoscopy coincided with radiologys in 81 of 186 cases (43.5%). The diagnosis of surgery or autopsy coincided with endoscopys in 48 of 52 cases (92.3%) and coincided wich radiologys in 20 of 29 cases (68.9%). There were four complications. Of these, bleeding occured in three patients, one patient died of respiratory failure al the time, six hours after endoscopie examination, we believe that emergency endoscopic examination during gastrointestinal bleeding is useful and safe.

    本文分析了内窥镜检查上消化道出血380例,发现阳性病变者341例(89.7%),溃疡病占首位43.7%,各种胃炎24.4%,肿瘤11.6%,食管静脉曲张3.68%。发现活动性出血及近期出血87例,其中48小时以内发现率55.56%,48小时以后18%。胃镜与X线诊断符合者43.5%,胃镜与手术或尸检符合串92.3%,X线与手术或尸检符合率68.9%。併发症4例,其中出血3例,1例检查后6小时呼吸衰竭死亡。我们认为在上消化道出血期间进行急症内窥镜检查是有益的也是安全的。

    Radioimmunoassay of serum gastrin was performed with 430 blood samples in different subjects. The fasting serum gastrin level obtained from 34 healthy people was 57±38 pg/ml, and showed no significant difference in sex distribution.Of the fasting serum gastrin level determined in patients with 15 kinds of various diseases, hypergastrinemia occurred in gastrinoma (one case, 700 pg/ml), diabetes mellitus (95 pg±16 pg/ml), hyperthyroidism (109±21 pg/ml) and uremia (171±41 pg/ml), and hypogastrinemia appeared in...

    Radioimmunoassay of serum gastrin was performed with 430 blood samples in different subjects. The fasting serum gastrin level obtained from 34 healthy people was 57±38 pg/ml, and showed no significant difference in sex distribution.Of the fasting serum gastrin level determined in patients with 15 kinds of various diseases, hypergastrinemia occurred in gastrinoma (one case, 700 pg/ml), diabetes mellitus (95 pg±16 pg/ml), hyperthyroidism (109±21 pg/ml) and uremia (171±41 pg/ml), and hypogastrinemia appeared in hypothyroidism (21±7 pg/ml). The fasting serum gastrin level was within normal limits in patients with the rest of diseases, such as peptic ulcer, chronic gastritis, subtotal gastrectomy, gastric cancer, liver cirrhosis, hypercorticalismus and hepatoma.Both hyperthyroidism and hypothyroidism showed no correlation between fasting serum gastrin level and serum T_3(or T_4) level, and their coefficient of correlation was 0.17 and 0.16 respectively.Except gastrinoma, both basal gastric acid secretion and peak gastric acid secretion after administration of maximal histamine were adversely related to the fasting serum gastrin level, namely, the higher the gastric acid level, the lower the gastrin level, and vice versa.After renal dialysis, the fasting serum gastrin level in patients with uremia decreased in the majority of patients, but there was no significant difference in comparison with the two groups before and after the dialysis.Fasting serum gastrin level always increased following gastroscopy, and the increment lasted for about two hours.There was no influence on fasting serum gastrin level at 30 minutes and 60 after administration of maximum histamine.The calcium provocative test was performed in order to increase the diagnostic effectivity in gastrinoma.We performed the preliminary observation on the G-cell in the gastric antrum.

    用放射免疫法测定血清胃泌素430例次。34例正常人空腹血清胃泌素为57±38pg/ml,男女无差别。为15种病患者测血清基础胃泌素含量,增高者有胃泌素瘤(1例,700pg/ml)、糖尿病(95±16pg/ml)、甲状腺机能亢进症(109±21pg/ml)、尿毒症(171±41pg/ml),减低者有甲状腺机能低下(21±7pg/ml)。其它如消化性溃疡、慢性胃炎、胃次全切除术后、胃癌、肝硬化、肾上腺皮质机能亢进、肝癌等均在正常范围。甲状腺机能亢进和机能低下患者,血清中的T_3或T_4含量,与其血清基础胃泌素含量的相关系数r分别为0.17和0.16,均不相关(P>0.05)。除胃泌素瘤外,胃酸(无论基础胃酸或最大组织胺后的高峰胃酸)与血清基础胃泌素含量间呈相反的关系,即胃酸愈高,胃泌素愈低,反之亦然。尿毒症经肾透析后,血清胃泌素多能下降,但将透析前后分别作为二组来比较,则无显著差异。胃镜检查后血清胃泌素显著上升,持续2小时方恢复正常。最大组织胺试验后30和60分钟时,对血清胃泌素含量无影响。开展钙兴奋试验,以提高对胃泌素瘤的诊断效率。对胃窦的G细胞进行了初步观察。

    During the period from Oct. 1979 through Feb. 1981, emergency endoscopy was done for acute upper gastrointestinal hemorrhage in 140 cases. Positive diagnosis was 92.8 %. Among them active or recent bleeding lesions were seen in 120 cases(85.7%). The detective rate for bleeding lesions was 93.9% within 24 hours, and 74.1% in 24-48 hours 17.8% of patients had more than one bleeding lesions. The primary causes of bleeding were peptic ulcer (34.3%), acute mucosal lesions (26.4%), carcinoma of the stomach (17.1%),...

    During the period from Oct. 1979 through Feb. 1981, emergency endoscopy was done for acute upper gastrointestinal hemorrhage in 140 cases. Positive diagnosis was 92.8 %. Among them active or recent bleeding lesions were seen in 120 cases(85.7%). The detective rate for bleeding lesions was 93.9% within 24 hours, and 74.1% in 24-48 hours 17.8% of patients had more than one bleeding lesions. The primary causes of bleeding were peptic ulcer (34.3%), acute mucosal lesions (26.4%), carcinoma of the stomach (17.1%), chronic gastritis (8.6%) and esophageal varices (2.1%). The endoscopic diagnosis coincided with barium meal radiography in 85 of 115 cases(73.9%), the diagnostic value of emergency endoscopy for various gastritis, peptic ulcer and gastric cancer, especially for acute mucosal lesion, was more sensitive than that of x-ray.Fifty active bleeders were managed by endoscopic local hemostasis. The efficacy of Monsell's solution or adona was more than 80 per cent. Rebleeding occurred in 4 cases (2.8%), but none died of complications during endoscopy. An erroneous diagnosis was made in 6 patients (4.3%). Therefore emergency endoscopy is a safe, reliable and highly efficacious diagnostic procedure. It could provide a reliable guide for proper treatment and should be done as soon as there is indication.

    对140例急性上消化道出血患者进行了紧急内窥镜检查(简称镜检),130例(92.8%)被发现出血病灶,其中120例(85.7%)见有活动性出血或近期出血。24小时内镜检者,出血病灶发现率为93.9%,24~48小时为74.1%。25例(17.8%)见有二个出血病灶。引起出血的主要病因有消化性溃疡(34.3%)、急性粘膜病变(26.4%)、胃癌(17.1%)和慢性胃炎(8.6%)。另10例(7.1%)出血原因不明。镜检对各种出血原因的诊断价值优于钡餐检查。4例(2.8%)于镜检后再度出血,但无一例因镜检而死亡。误诊和漏诊共6例(4.3%)。紧急内窥镜检查安全、可靠、确诊率高,有助于及早采取合理的治疗和减少不必要的手术探查。

     
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