Results: The acute radiation bronchitis rates were 40.0% and 16.1% in CRT group and LCHSRT group respectively(χ~2=4.322,P<0.05); there are statistical difference between the two groups. The radiation pneumonia rates were 26.7% and 6.5% in CRT group and LCHSRT group respectively(χ~2=4.546,P<0.05);
AIM: To construct a eukaryotic expression bicistron plasmid vector pIRES2-EGFP-FLT3 in order to investigate the role of FLt3 in the hemopoiesis and immune function during the recovery of acute radiation combined injury.
With the development of gene engineering technology, more and more high purity recombinant hematopoietic factors can be caquired, which is vital in the experimental research and clinical therapy of acute radiation injury.
The result indicated that after rabbits were irradiated continuously by γ-ray at 0.26 mGy/min(0.05Gy/d) for 20 days (accumulation dose 1.0Gy), and immediatly acutely irradiated to 2.0 Gy (at 0.25Gy/min), the chromosome aberration frequency and micronucleus frequency in peripheral blood lymphocytes significantly decreased and lymphocyte transformation frequency significantly increased in comparison with acute radiation control group.
In this paper, influence of chronic γ-ray radiation on chromosome aberration, mi-cronucleus and transformation frequency in peripheral blood lymphocytes in rabbits induced by acute radiation was described.
(2) However, with the increase of radiation doses the counts of peripheral and thymus lymphocytes decreased sharply, which showed an opposite change to lymphocyte apoptosis. This suggests that apoptosis may be one of the major causes of lymphocyte reduction after acute radiation.