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disease
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  病情
    A STUDY OF CORRELATION OF URINARY BIOCHEMICAL COMPOSITION AND STATE OF KASHIN-BECK'S DISEASE
    大骨节病患者尿液生化成分与大骨节病病情相关性研究
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    Study on correlation between the chemical elemental content in the hair of children suffered from Kashin-Beck disease with incidence
    大骨节病儿童发中化学元素含量与病情的相关性研究
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    Serum C-Reactive Protein Measurement of Disease Activity in Dermatosis
    血清C-反应蛋白测定对皮肤病及其病情活动的临床意义
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    Investigation and Analysis of Keshan Disease in Zhangjiakou District
    张家口地区克山病病情现状与分析
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    Dynamic Analysis of State of lodine Deficiency Disease in Huzhu County,Qinghai Province
    青海省互助县缺碘性疾病病情动态分析
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  病患者
    Study on Associations of VEGF, IGF-I and bFGF with Intrathyroidal Angiogenesis and Thyroid Volumes in Patients with Grave's Disease
    VEGF、IGF-1、bFGF与Graves病患者甲状腺内血管形成及甲状腺体积关系的研究
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    Determination of Serum Thyroid Stimulating Immunoglobulin and Its Clinical Significance in Patients with Graves' Disease
    Graves氏病患者血清甲状腺刺激免疫球蛋白的测定及其在临床上的意义
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    LONG-TERM OUTCOME OF 284 CASES OF GRAVES' DISEASE AFTER CESSATION OF ANTITHYROID DRUGS
    284例Graves病患者抗甲状腺药治疗后的远期预后
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    HLA OF DIABETES WITH GRAVES' DISEASE IN CHINESE
    我国糖尿病合并Graves’病患者HLA类型分布研究
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    THE ABNORMALITIES OF T CELL SUBSETS IN GRAVES' DISEASE
    Graves病患者T细胞亚群异常的研究
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    The Relationship between Mannose-binding Lectin (MBL) and Rheumatic Heart Disease and Recombinant MBL Protein Expression
    甘露糖结合凝集素与风湿性心脏病的关系及其重组蛋白的表达
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    Mapping the Disease Gene in a Disseminated Superficial Actinic Porokeratosis Family and Study Susceptibility Genes of Late-onset Type 2 Diabetes Mellitus
    对一个弥漫性浅表性光敏性汗孔角化症家系致病基因的定位和对迟发型2型糖尿病易感基因的研究
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    The Factors Influencing Plasma Homocysteine in Type 2 Diabetes and the Relationship between Homocysteine and Diabetic Vascular Disease
    2型糖尿病中影响血浆同型半胱氨酸水平的因素及其与血管并发症的关系
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    Study on the Association of Single Nucleotide Polymorphisms in Apolipoprotein APOA1/C3/A4/A5 Gene Cluster with Coronary Heart Disease and Type Ⅱ Diabetes
    载脂蛋白APOA1/C3/A4/A5基因簇与冠心病、糖尿病脂代谢相关性研究
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    The Experimental Study on Relationship between Angiopoietins/Tie-2 Axis and Diabetic Renal Microvascular Disease
    Angiopoietins/Tie-2与糖尿病肾脏微血管病变关系的实验研究
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  disease
Mechanisms and Issues Relating to the Use of D1-like Dopamine Receptor Agonists for Age-related Illnesses: Parkinson's Disease a
      
Furthermore, acetylcholinesterase and butyrylcholinesterase inhibitors such as tacrine, donepezil, rivastigmine, and galantamine are currently used to manage Alzheimer's disease.
      
Since amlodipine besylate is a very potent inhibitor of both cholinesterases, amlodipine besylate may, like donepezil, be useful in Alzheimer's disease treatment.
      
According to the protocol of the National Cancer Institute (NCI) in vitro disease-oriented human cells screening panel assay, 13 compounds showed promising broad spectrum antitumor activity.
      
Epidemiologic model of SIS type has a delay corresponding to the infectious period and disease-related deaths, so that the population size is variable.
      
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The clinical data of 14 patients suffering from non-nutritional adultosteomalacia were reported. In 11 cases, a mixed- type of osteopathy hadbeen found roentgenographically. The underlying abnormalities of most ofthe cases were of renal tubular origin. Primary hyperparathyroidism seemedto be a second predominant disorder producing this kind of bone disease.The facets of clinical diagnosis and pathogenesis of the disease were dis-cussed. Owning to the fact that the diseases were often overlooked...

The clinical data of 14 patients suffering from non-nutritional adultosteomalacia were reported. In 11 cases, a mixed- type of osteopathy hadbeen found roentgenographically. The underlying abnormalities of most ofthe cases were of renal tubular origin. Primary hyperparathyroidism seemedto be a second predominant disorder producing this kind of bone disease.The facets of clinical diagnosis and pathogenesis of the disease were dis-cussed. Owning to the fact that the diseases were often overlooked or wro-ngly diagnosed in early stage both clinically and roentgenogrphically, it isdiserable that meticulous attention should be paid to the management ofthe suspected patients of this disease.

本文报告14例成人骨软化的临床资料。对本病的临床诊断和发病机理作了讨论。

101 patients with various dermatoses, including Sweet's syndrome, lupus erythematosus, erythroderma, psoriatic arthritis, allergic angiitis etc., were successfully treated with total glucosides (TG) extracted from the Chinese herbal drug"Lei-Gong-Teng" (Tripterygium Wilfordii Hook F) . Our observations showed; ( 1 ) diseases which showed good response to corticosteroids also responded satisfactorily to TG, ( 2 ) the action of TG was quicker and more potent than that of corticosteroids, and ( 3 ) there...

101 patients with various dermatoses, including Sweet's syndrome, lupus erythematosus, erythroderma, psoriatic arthritis, allergic angiitis etc., were successfully treated with total glucosides (TG) extracted from the Chinese herbal drug"Lei-Gong-Teng" (Tripterygium Wilfordii Hook F) . Our observations showed; ( 1 ) diseases which showed good response to corticosteroids also responded satisfactorily to TG, ( 2 ) the action of TG was quicker and more potent than that of corticosteroids, and ( 3 ) there was no rebound phenomenon on withdrawal of TG.The clinical side effects of TG were of mild intensity and included stomach ache, anorexia, burning sensation of esophagus, leukopenia, fatigue, drowsiness, vertigo, fever, dryness of mouth, nose and pharynx, all these side effects were reversible upon reduction of daily dosage.We suggest that corticosteroids can be substituted by TG in the treatment of most allergic dermatoses. But the therapeutic index is comparatively small, so the dosage should be strictly controlled. It is postulated that the mode of action of TG may be similar to that of corticosteroids. Further investigations will be done on the chemical structure and the pharmacological action of TG.

用雷公藤总甙治疗隆起性红斑、红皮病、红斑狼疮、银屑病性关节炎及变应性血管炎等皮肤病101例,取得较好结果。一般对皮质类固醇有效的疾病,用此药均获良效,而且抗炎作用强,生效快,小剂量即有治疗活性,停药后无反跳现象,可以代替皮质类固醇治疗多种变态反应性皮肤病。但其治疗指数较小,剂量应严格掌握。

Quantitative determinations of serum β-lipoprotein,cholesterol and trigly-ceride and agarose-gel electrophoresis have been made on normal subjects andpatients with coronary heart disease(CHD),myocardium infarction(MI)andhypertension,totalling 247 cases.According mainly to the data of agarose elec-trophoretograms,the 247 subjects could be classified into seven different types,namely,types Ⅱ_1,Ⅱ_2,Ⅱ_3,Ⅱ_4,Ⅲ,Ⅳ,and Ⅴ.The distribution of these 247 casesin each type was different,being the highest in type Ⅱ(88...

Quantitative determinations of serum β-lipoprotein,cholesterol and trigly-ceride and agarose-gel electrophoresis have been made on normal subjects andpatients with coronary heart disease(CHD),myocardium infarction(MI)andhypertension,totalling 247 cases.According mainly to the data of agarose elec-trophoretograms,the 247 subjects could be classified into seven different types,namely,types Ⅱ_1,Ⅱ_2,Ⅱ_3,Ⅱ_4,Ⅲ,Ⅳ,and Ⅴ.The distribution of these 247 casesin each type was different,being the highest in type Ⅱ(88 cases)and the lowestin type Ⅴ(2 cases).The order of the overall distribution was as follows:TypesⅡ_4,>Ⅱ_3>Ⅳ>Ⅱ_1vⅡ_2>Ⅲ>Ⅴ.Among the 247 subjects examined,there were 118 cases of hyper-β-lipopro-teinemia.Their distribution in each type was similar to the above results,beingalso highest in type Ⅱ_4(44 cases),and lowest in type Ⅴ(2 cases).The overalldistribution was that Ⅱ4>Ⅳ>Ⅱ_3>Ⅱ_1>Ⅲ>Ⅲ>Ⅴ.Amongthe 118 cases of hyper-β-lipoproteinemia studied,there were 67 casesof CHD,34 cases of hypertension and 20 cases of MI.The distribution of CHDin different phenotypes of hyper-β-lipoproteinemia of types Ⅱ_4,Ⅳ and Ⅱ_3 wasabout the same,being 22,20 and 18 cases respectively,that in types Ⅱ_1 and Ⅱ_2was much lower,being 4 and 3 cases respectively,and there was none in types Ⅲand Ⅴ.MI also occurred quite frequently in types Ⅳ,Ⅱ_4 and Ⅱ_3 but none intypes Ⅲ and Ⅴ.Furthermore,it was found that both CHD and hypertension were moreclosely related with hyper-β-lipoproteinemia than with hypercholesterolemia andtriglyceridemia.All above results imply that an early discovery and diagnosis of hyper-lipo-proteinemia would be of value to the prevention and treatment of CHD and MI.

本文对正常、冠心病及心肌梗塞病人共247例的血清进行了琼脂糖电泳和胆固醇、甘油三酯及β脂蛋白的含量测定。主要根据βLP 电泳图象的类型,必要时参考血清脂质含量将247例被检人员分为Ⅱ-1、Ⅱ_2、Ⅱ_3、Ⅱ_4、Ⅲ、Ⅳ、Ⅴ七种不同的类型。按其在每种类型中分布多少排列次序如下:Ⅱ_4>Ⅱ_3>Ⅳ>Ⅱ-1>Ⅱ_2>Ⅲ>Ⅴ。以Ⅱ_4最多,88例,Ⅴ型最少,仅2例。247例中118例有高脂蛋白血症。他们在各型中的分布情况亦以Ⅱ_4型为最多,Ⅴ型最少。排列次序与上述情况类似;为Ⅱ_4>Ⅳ>Ⅱ_3>Ⅱ_2>Ⅱ-1>Ⅱ>Ⅴ型。118例高脂蛋白血症者中67例有冠心病,34例有高血压,20人有 MI。冠心病的分 布以Ⅱ_4,Ⅳ及Ⅱ_3型较多,Ⅱ_1型中最少,Ⅲ、Ⅴ型中无,但以本型计则发病率以Ⅱ_2、Ⅱ_1和Ⅱ_3较多,Ⅱ_4及Ⅳ型中较少,MI 多集中于Ⅳ、Ⅱ_4及Ⅱ_3型中。说明Ⅱ及Ⅳ型与冠心病的关系较为密切。此外,还观察了104例冠心病和42例高血压在各型中的分布,发现二者均较集中地分布于Ⅱ_4Ⅳ及Ⅱ_3型中。比较了它们在高 Tg、高 Ch 及高脂蛋白血症中的发生率。发现冠心病和高血压与高脂蛋白血症的关系比高 Ch 及高 T...

本文对正常、冠心病及心肌梗塞病人共247例的血清进行了琼脂糖电泳和胆固醇、甘油三酯及β脂蛋白的含量测定。主要根据βLP 电泳图象的类型,必要时参考血清脂质含量将247例被检人员分为Ⅱ-1、Ⅱ_2、Ⅱ_3、Ⅱ_4、Ⅲ、Ⅳ、Ⅴ七种不同的类型。按其在每种类型中分布多少排列次序如下:Ⅱ_4>Ⅱ_3>Ⅳ>Ⅱ-1>Ⅱ_2>Ⅲ>Ⅴ。以Ⅱ_4最多,88例,Ⅴ型最少,仅2例。247例中118例有高脂蛋白血症。他们在各型中的分布情况亦以Ⅱ_4型为最多,Ⅴ型最少。排列次序与上述情况类似;为Ⅱ_4>Ⅳ>Ⅱ_3>Ⅱ_2>Ⅱ-1>Ⅱ>Ⅴ型。118例高脂蛋白血症者中67例有冠心病,34例有高血压,20人有 MI。冠心病的分 布以Ⅱ_4,Ⅳ及Ⅱ_3型较多,Ⅱ_1型中最少,Ⅲ、Ⅴ型中无,但以本型计则发病率以Ⅱ_2、Ⅱ_1和Ⅱ_3较多,Ⅱ_4及Ⅳ型中较少,MI 多集中于Ⅳ、Ⅱ_4及Ⅱ_3型中。说明Ⅱ及Ⅳ型与冠心病的关系较为密切。此外,还观察了104例冠心病和42例高血压在各型中的分布,发现二者均较集中地分布于Ⅱ_4Ⅳ及Ⅱ_3型中。比较了它们在高 Tg、高 Ch 及高脂蛋白血症中的发生率。发现冠心病和高血压与高脂蛋白血症的关系比高 Ch 及高 Tg 血症更为密切。以上结果均说明Ⅱ、Ⅳ型与冠心病、高血压有密切关系,因此对该二型高脂蛋白血症的早期发现和治疗对冠心病的防治看重要意义?

 
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