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disease
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    The Study of the Relationship between Polymorphism of Apolipoprotein B Gene and Cerebrovascular Disease
    载脂蛋白B基因多态性与脑血管关系研究
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    Study on the Related Genes of Parkinson Disease
    帕金森相关基因研究
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    The Experimental and Clinical Study on Neuron Functional Imaging for Parkinson's Disease
    帕金森的实验和临床神经功能影像学研究
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    Experimental and Clinical Study of ~1H MRS and ~(99m)Tc-TRODAT-1 SPECT Imaging in the Brain of Parkinson's Disease
    帕金森的脑~1H MRS和~(99m)Tc-TRODAT-1 SPECT显像的动物实验及临床应用研究
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    Molecular Biological Study on Borna Disease Virus Infection in Neuropsychiatric Patients
    神经精神人博尔纳毒感染的分子生物学研究
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  病的
    The Experimental and Clinical Study on Neuron Functional Imaging for Parkinson's Disease
    帕金森病的实验和临床神经功能影像学研究
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    Experimental and Clinical Study of ~1H MRS and ~(99m)Tc-TRODAT-1 SPECT Imaging in the Brain of Parkinson's Disease
    帕金森病的脑~1H MRS和~(99m)Tc-TRODAT-1 SPECT显像的动物实验及临床应用研究
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    Basic Researches on BDNF Gene-Modified Human Bone Marrow Mesenchymal Stem Cells Transplantation into a Rat Model of Parkinson's Disease
    BDNF基因修饰的人骨髓间充质干细胞移植治疗帕金森病的实验研究
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    Study on the Risk Factors for the Idiopathic Parkinson's Disease
    原发性帕金森病的危险因素研究
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    Relationships between ATP Sensitive Potassium Channels and Parkinson's Disease
    ATP敏感性钾通道和帕金森病的相关性研究
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  病患者
    Platlet Aggregation in Acute Ischemic Cerebral Vascular Disease
    急性缺血性脑血管病患者血小板聚集率——介绍检查血小板聚集性的新方法
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    The Etiologic Study of Cerebrovascular Disease
    脑血管病的病因研究——黑龙江省808例脑血管病患者病例-对照研究及Logistic回归分析
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    STUDY OF COMPLEMENT 3′S ABILITY IN THE ELIMINATION OF CIRCULATORY IMMUNE COMPLEX IN PATIENTS WITH CEREBROVASCULAR DISEASE
    脑血管病患者补体C_3对免疫复合物清除能力的研究
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    DETERMINATION OF PLATELET-ASSOCIATED IgG IN 113 PATIENTS WITH CEREBROVASCULAR DISEASE
    脑血管病患者血小板相关抗体的测定(附113例报告)
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    Analysis of the Changes of Content of High Density Lipoprotein Subfraction and Apolipoproteins A 1 and B in Acute Cerebrol Vessel Disease
    急性脑血管病患者血清高密度脂蛋白亚组分与ApoA_1,B含量变化的分析
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    Establishment of Cell Models for Parkinson's Disease in Vitro and the Neuroprotective Effect of Citicoline on Dopaminergic Neurons
    帕金森氏病体外细胞模型的建立及胞二磷胆碱对多巴胺能神经元保护作用的研究
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    Clinical, Electrophysiological, Pathological, and Genetic Study in Chinese Charcot-Marie-Tooth Disease Patients with Type 1A and X-linked
    中国人群中CMT1A和CMTX的临床、电生理、病理和遗传研究
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    Study on the Neurotoxicity of CSF from Patients with Parkinson Disease and the Protection of MAO-B Inhibitor and Dopamine Agonist Against the Toxicity
    帕金森病人脑脊液神经毒性及单胺氧化酶-B抑制剂和多巴胺激动剂的保护作用的研究
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    The Value of the Quantity of 14-3-3 Protein in the Cerebrospinal Fluid and Enhanced Expression in the Brains for Diagnosis of Creutzfeldt-Jakob Disease
    脑脊液14-3-3蛋白的定量检测及脑组织内的表达对sCJD诊断价值的研究
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    Mapping, Candidate Cloning of a Novel Disease Gene for BFIC and the Mutation Analysis of KCNQ3 Gene in BFNC Families
    新的BFIC致病基因的定位、候选克隆及BFNC的KCNQ3基因突变检测
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  disease
Mechanisms and Issues Relating to the Use of D1-like Dopamine Receptor Agonists for Age-related Illnesses: Parkinson's Disease a
      
Furthermore, acetylcholinesterase and butyrylcholinesterase inhibitors such as tacrine, donepezil, rivastigmine, and galantamine are currently used to manage Alzheimer's disease.
      
Since amlodipine besylate is a very potent inhibitor of both cholinesterases, amlodipine besylate may, like donepezil, be useful in Alzheimer's disease treatment.
      
According to the protocol of the National Cancer Institute (NCI) in vitro disease-oriented human cells screening panel assay, 13 compounds showed promising broad spectrum antitumor activity.
      
Epidemiologic model of SIS type has a delay corresponding to the infectious period and disease-related deaths, so that the population size is variable.
      
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This is a clinico-electroencephalographic report of seven typical cases of subacute sclerosing panencephalitis with a discussion of certain aspects of the disease. Correct and early diagnosis of the disease hinges on the total clinical picture rather than any isolated symptom or/and sign. The diagnosis of this disease is more aptly established if the case is associated with fairly typical EEG findings, biochemical and immunological studies of the blood and spinal fluid and morphological findings...

This is a clinico-electroencephalographic report of seven typical cases of subacute sclerosing panencephalitis with a discussion of certain aspects of the disease. Correct and early diagnosis of the disease hinges on the total clinical picture rather than any isolated symptom or/and sign. The diagnosis of this disease is more aptly established if the case is associated with fairly typical EEG findings, biochemical and immunological studies of the blood and spinal fluid and morphological findings of the biopsied specimen of the brain. Case 2 was a boy of 7 years old who had been noted to have speech difficulty and memory defect for several months and one generalized seizure the day before he was seen on Feb. 8, 1977. Under the treatment of anticonvulsants and steroids he apparently had two periods of remission. He contracted measles two years after the onset of his illness but without evident symptoms. Case 6 had been treated in a mental hospital as a case of schizophrenia. The corrent diagnosis in this case was made on the basis of the total clinical picture and EEG findings. Anticonvulsants , cytoarabinose , amantadine , steriod , supportive measures and good nursing care have made him more alert and improved his general condition to the satisfaction of his family though he is still demented. Both these two cases had had serial EEG examinations.

本文报告了临床和脑电图?见

From January 1,1966 through December 31,1975, 416 patients with acute myocardial infarction were hospitalized in Capital Hospital. 134 of them died within 8 weeks after the onset of the disease.The death rate in acute stage was 32.2%. 275 of the 282 patients who survived through the acute stage were followed-up for more than halfayear. 239 of the 271 cases which were followed up for oue year survived. The one-year survival rate was 88.2%. 124 cases were followed-up for more than 5 years. among them 84...

From January 1,1966 through December 31,1975, 416 patients with acute myocardial infarction were hospitalized in Capital Hospital. 134 of them died within 8 weeks after the onset of the disease.The death rate in acute stage was 32.2%. 275 of the 282 patients who survived through the acute stage were followed-up for more than halfayear. 239 of the 271 cases which were followed up for oue year survived. The one-year survival rate was 88.2%. 124 cases were followed-up for more than 5 years. among them 84 were alive. The five-year survival rate was 67.7. 25 cases were followed up for more than ten years. 10 of them were still living. The ten-year survival rate was 40%. 92 of the 275 patients died during the follow up period. 56 cases(60.9%) died of cardiopathy, especially cardiac failure. Cerebrovascular accidents and cancers of various origin were the main other causes of death.183 patients survived through the follow-up period were questioned about their work abilities.164 (89.6%) of them returned to their work partially or completely, either in their original professeons or house works. 19(10.4%) of the 183 patients could not earn their routine living by themselves because of their old ages,cardiac insufficiencies or sequelae from cerebrovascular accidents.

本文报导对1966~1975十年内首都医院收治的416例急性心肌梗塞患者随访调查结果。急性期病死率32.2%。急性期后存活282例,随访半年以上者275例,随访率97.5%。随访一年生存率88.2%。随访五年生存率67.7%。随访十年生存率40.O%。随访死亡病例死于心内原因者60.9%,主要死于心力衰竭者占心脏原因的51.8%。急性期合併心衰者60例,随诊死亡率50%,无心衰者215例,随诊死亡62例,死亡率29%。随访死亡病例死于心外原因者以脑血管疾患和各种癌瘤为多。本组病例存活者183例,部分或全部恢复劳动能力者164例(89.6%),完全丧失劳力者19例(10.4%),主要因年迈,心功能不全或合併脑血管意外后遗症。

57 cases of multiple sclerosis were admitted since 1949-1979 with an incidence of 1% of neurological admissions. 27 male and 30 female patients came in with a mean age of 33 years. Prodromal symptoms did not differ from that in literature. They were chiefly first struck with visual impairment and motor paralysis and less frequently with diplopia,vertigo and ataxia. The incidence of abnormal EEG was 49.12%(28 cases), including 13 local foci. EEG changes bore no relation to age (on admission or at onset), sex,...

57 cases of multiple sclerosis were admitted since 1949-1979 with an incidence of 1% of neurological admissions. 27 male and 30 female patients came in with a mean age of 33 years. Prodromal symptoms did not differ from that in literature. They were chiefly first struck with visual impairment and motor paralysis and less frequently with diplopia,vertigo and ataxia. The incidence of abnormal EEG was 49.12%(28 cases), including 13 local foci. EEG changes bore no relation to age (on admission or at onset), sex, occupation, course, mode of onset and symptoms but state of disease activity. Most of the cases suffered from visual impairment and motor paralysis at time of discharge. Six patients died. Diagnosis established at autopsy in two cases. Author suggested that serial EEG studies was helpful in depicting cortical dysfunction at early stage of disease.A normal tracing did not exclude slight cortical lesions in cerebral hemispheres.

本院自1949~1979共收治57例多发性硬化患者,约占同期神经科住院病人总人次之1%。男27,女30例,平均年龄33岁,平均病程31个月,大部分为亚急性,先兆症状与文献报道相似。首发神经症状主要为视力障碍及截瘫;复视、眩晕或共济失调则较少。脑电图异常者28例(49.1%),其中13例有局灶。脑电图变化与年龄、病程、发病方式或临床表现无关,但与临床情况及过程有一定关系。

 
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