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      acetyl cysteine
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  乙酰半胱氨酸
     Methods Cultured BAEC was exposed to MMA~Ⅲ(0.75?μmol/L,0~15?min)without or with acetylcysteine(NAC)pretreatment(1?mmol/L,2?h),or iAs~Ⅲ(100?(μmol/L,)0~60?min).
     亚砷酸钠(iAsⅢ,100μmol/L,0~60 min); 或N-乙酰半胱氨酸(NAC,1 mmol/L)预处理2 h后,再暴露于MMAⅢ(0.75μmol/L,0~15 min)。
短句来源
     RESULTS The dissolution limit of acetylcysteine dissolution was 80%.
     结果 :乙酰半胱氨酸溶出度限度为 80 %;
短句来源
     Objective To explore N acetylcysteine (NAC) effects on the expression of interleukin (IL) 8, IL 6 and TNFα by PBMC.
     目的 研究N 乙酰半胱氨酸(NAC)体外对白细胞介素 8(IL 8)、白细胞介素 6(IL 6 )及肿瘤坏死因子α(TNFα)在外周血单核细胞 (PBMC)中表达的影响。
短句来源
     Objective To study the intervention effect of a new antioxidant N acetylcysteine (NAC) on the apoptosis of neurocytes of newborn rats with hypoxic ischemic encephalopathy (HIE).
     目的探讨新型抗氧化剂N-乙酰半胱氨酸(N-acetylcysteine,NAC)对缺氧缺血性脑病(Hypoxic-ischemicencephalopathy,HIE)新生鼠脑细胞凋亡的干预效果。
短句来源
     OBJECTIVE:To determine the relations of IL 1 mRNA and protein expressive law in ischemical myocardium and reperfusion injury and observe the effect of N acetylcysteine(NAC) on ischemia tissues.
     目的:研究IL-1mRNA及蛋白在缺血心肌的表达规律及与再灌注损伤之间的关系,并观察N-乙酰半胱氨酸(N-acetylcysteine,NAC)对缺血组织的影响。
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  乙酰半胱氨酸
     Methods Cultured BAEC was exposed to MMA~Ⅲ(0.75?μmol/L,0~15?min)without or with acetylcysteine(NAC)pretreatment(1?mmol/L,2?h),or iAs~Ⅲ(100?(μmol/L,)0~60?min).
     亚砷酸钠(iAsⅢ,100μmol/L,0~60 min); 或N-乙酰半胱氨酸(NAC,1 mmol/L)预处理2 h后,再暴露于MMAⅢ(0.75μmol/L,0~15 min)。
短句来源
     RESULTS The dissolution limit of acetylcysteine dissolution was 80%.
     结果 :乙酰半胱氨酸溶出度限度为 80 %;
短句来源
     Objective To explore N acetylcysteine (NAC) effects on the expression of interleukin (IL) 8, IL 6 and TNFα by PBMC.
     目的 研究N 乙酰半胱氨酸(NAC)体外对白细胞介素 8(IL 8)、白细胞介素 6(IL 6 )及肿瘤坏死因子α(TNFα)在外周血单核细胞 (PBMC)中表达的影响。
短句来源
     Objective To study the intervention effect of a new antioxidant N acetylcysteine (NAC) on the apoptosis of neurocytes of newborn rats with hypoxic ischemic encephalopathy (HIE).
     目的探讨新型抗氧化剂N-乙酰半胱氨酸(N-acetylcysteine,NAC)对缺氧缺血性脑病(Hypoxic-ischemicencephalopathy,HIE)新生鼠脑细胞凋亡的干预效果。
短句来源
     OBJECTIVE:To determine the relations of IL 1 mRNA and protein expressive law in ischemical myocardium and reperfusion injury and observe the effect of N acetylcysteine(NAC) on ischemia tissues.
     目的:研究IL-1mRNA及蛋白在缺血心肌的表达规律及与再灌注损伤之间的关系,并观察N-乙酰半胱氨酸(N-acetylcysteine,NAC)对缺血组织的影响。
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  “acetyl cysteine”译为未确定词的双语例句
     The average recovery of acetylcysteine was 101.2%(RSD<0.6%).
     平均回收率为101.2%,RSD<0.6%;
短句来源
     The average recovery of acetylcysteine was 99.3% with RSD of 0.6% by high performance liquid chromatography.
     以高效液相色谱法进行含量测定 ,平均回收率为 99.3%,RSD为0 .6 %。
短句来源
     The average recovery of acetylcysteine was 99.2% with RSD of 1.4% by oxido-reductometric method.
     以氧化还原滴定法进行含量测定 ,平均回收率为 99.2 %,RSD为 1 .4 %;
短句来源
     mL of acetylcysteine with correlation coefficient being 0. 999 9(n =5) ,the average recovery was 99. 1 % ~ 101. 9% ( RSD < 0. 60% , n -3).
     平均回收率(n=3 )为99.1%~101.9%,RSD<0.60%,。
短句来源
     Conclusion N acetylcysteine antagonizes the production of interleukin 8, interleukin 6 and TNFα stimulated by PMA and A23187 in PBMC.
     结论 NAC体外可以下调PMA、A23187刺激PBMC表达IL 8、IL 6及TNFα。
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  acetyl cysteine
Surrogate replacement of Gpx1 with the reactive oxygen species scavenger N-acetyl cysteine and the Gpx1 mimetic ebselen, reverses the Gpx1-/- increased susceptibility to Aβ toxicity.
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Effect of Chronic N-Acetyl Cysteine Administration on Oxidative Status in the Presence and Absence of Induced Oxidative Stress i
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N-acetyl cysteine (NAC) provides thiol groups to glutathione and to mitochondrial respiratory chain proteins; thus, it may counteract both ROS generation and effects.
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Both insulin resistance state and the elevated MG level were reversed by the MG scavenger, N-acetyl cysteine (NAC).
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On the other hand, pre-incubation of myocytes with N-acetyl cysteine (NAC) reduced the effects of ouabain on contractility, but not [Ca2+]i.
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         The urinary metabolite of acrylamide, mercapturic acid [N-acetyl cysteine-s-propionamiue (APC)],was measured by the Ellman's method using 5, 5-dithio-bis (2-nitrobenzoic) acid, which yields a yellow product. C_(18) cartidge was used for cleaning up and concentrating urine sample. The concentrated sample was eluted with methanol-water. The APC and/or other thiocther were determined by the difference between absorbances with and without alkaline hydrolysis of the eluted solution. The coefficients ...
            采用C(18)小柱净化尿样,富集尿中被测物丙烯酰胺代谢物──巯基尿酸(乙酰半胱氨酸-S-丙酰胺)。处理过的尿样用Ellman's反应分光光度法测定。用本方法做游离巯基测定的批内变异系数为0.14%~1.6%(n=6),总巯基测定的批内变异系数为1.0%~5.2%(n=6),方法的加标回收率为82.7%~84.4%。检出下限:游离巯基尿酸为0.008mmol/L,总巯基尿酸为0.013mmol/L。本方法测定了9例非接触者尿样,巯基尿酸浓度范围0.056~0.086mmol/L,41例接触丙烯酰胺工人的尿,巯基尿酸浓度范围0.061~0.374mmol/L。
文摘来源
         Cystaminc(CA,10-100μmol·L-1)induced dose-dependent vasorelaxation in rabbitaortic rings(RA R) precontracted with phenylephrine(Phe,1 μmol·L-1).Presence or absence ofendothelium did not influence the vasorelaxation effectof CA. Incubation of RAR with CA(100 μmol·L-1)for 5 h resulted in remarkable reduction of sensitivityto Phe(1 nmol·L-1 -40 μmol·L-1),a right shift ofthe contraciton curve and an increase of EC50.Thedepressant effect was not seen in incubation withcysteamine,cysteine and N-acetyl-...
            用兔离体主动脉环观察腕胺对苯福林缩血管作用的影响以及与一氧化氮代谢的关系10—100μmol·L ̄(-1)的胱胺在苯福林预收缩的兔主动脉环表现缓慢而完全的舒张作用,呈剂量和时间依赖性,与内皮细胞存在与否无关。100μmol·L(-1)脱胺预温育5h,使主动脉环对苯福林的收缩敏感性明显降低,EC_(50)增加,最大收缩力下降。胱胺结构类似物半胱胺,半胱氨酸,N—乙酰半脱氨酸均未见抑制血管收缩力的作用。亚甲基蓝(10μmol·L ̄(-1)),血红蛋白(1μmol·L ̄(-1))及N_ω—硝基精氨酸(100μmol·L ̄(-1))均可部分反转胱胺对血管收缩力的抑制,使标本的最大收缩力恢复(P<0.05),提高标本对苯福林的敏感性,结果表明,胱胺对血管平滑肌有直接舒张作用,其机理可能与血管平滑肌细胞的一氧化氮代谢途径有关。
文摘来源
         Objectives:To study the mechanism of dopaminergic neuronal death in substantia nigra of Parkinson's diseaes(PD). Methods:The effect of dopamine(DA) on apoptotic PC12 cell were examined by fluorescence microscopy using the DNA end-labeling methods. Results:DA may induce apoptosis in PC 12 cell,moderate concentrations of DA(0.45mmol/L4) giving maximal number of apoptotic cell (rate of apoptosis:48.7%±6.3%);and the antioxidant N-acetyl-cysteine(NAC) partially prevent DA-induced apoptosis in PC12 ce...
            目的:研究帕金森病(PD)黑质多巴胺(DA)神经元的死亡机制。方法:用脱氧核糖核酸(DNA)标记法,借助荧光显微镜观察多巴胺对PC12细胞凋亡的影响。结果:DA可诱发PC12细胞凋亡,适中浓度时(0.45mmol/L)PC12细胞凋亡数最多(凋亡率为48.7%±6.3%);抗氧化剂N乙酰半胱氨酸(NAC)可部分阻止DA诱发的PC12细胞凋亡(P<0.01)。结论:凋亡参与了PD的病变过程,采用适当的抗氧化剂对于PD治疗具有积极的意义
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