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   acute exacerbation 在 感染性疾病及传染病 分类中 的翻译结果: 查询用时:0.128秒
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acute exacerbation
相关语句
  急性发作
    Relationship between HBV DNA serum level and acute exacerbation of the disease in chronic hepatitis B patients
    慢性乙型肝炎急性发作与血清HBV DNA含量关系
短句来源
    The Study of Immune Response of Th1/Th2 Cells in Chronic Hepatitis B Patients during Acute Exacerbation
    Th1/Th2细胞在慢性乙型肝炎急性发作的免疫应答研究
短句来源
    To investigate the immune response of Th1/Th2 cells to HBV duplication and subsequent injury of liver cells through detection of Th1/Th2 cells’ ratio, HBV DNA load and liver function indexes in peripheral blood of chronic hepatitis B patients during acute exacerbation.
    目的: 通过检测慢性乙型肝炎急性发作患者外周血Th1及Th2细胞的百分比及Th1/Th2的比值、乙型肝炎病毒(HBV)DNA载量以及肝功能的状况,了解在乙型肝炎病毒复制及肝细胞受损时Th1/Th2细胞免疫应答的变化情况 。
短句来源
    Results: (1) The percentage of Th1 cells(14.52±4.86%) in chronic HBV infectants during acute exacerbation was higher than that these patients after treatment(9.33±2.72%)(P<0.05) and that of normal controls(9.92±4.54%)(P<0.05).
    结果:(1)在慢性乙型肝炎急性发作时Th1细胞百分比(14.52±4.86%)明显高于治疗后(9.33±2.72%)(P<0.05),也比正常对照组高(9.92±4.54%)(P<0.05);
短句来源
    Similarly, the ratio of Th1/Th2 during acute exacerbation was higher than that of normal controls (P<0.05) and that these patients after treatment (P<0.05). There was no statistic difference of Th2 cells percentage between cases and controls(P>0.05).
    急性发作时Th2细胞百分比(1.64±0.59%)与治疗后(1.81±0.75%)相比较无显著性差异(P>0.05),与正常对照组(2.058±0.985%)相比较也无显著性差异;
短句来源
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  “acute exacerbation”译为未确定词的双语例句
    The Relations between the Replication of HBV and the Changes of the Beta-2-Microglobulin Levels in Patients with Acute Exacerbation of Chronic Hepatitis B
    慢性乙型肝炎活动期HBV复制与血清β_2-MG变化的关系
短句来源
    The Relations between the Replication of HBV and the Changes of the Immune Function in Patients with Acute Exacerbation of Chronic Hepatitis B
    慢性乙肝活动期HBV复制与免疫功能变化的探讨
短句来源
    ESR of 25 cases were 72.8±36.3mm/h,white blood cell increased(>1.1×10 9/L)only in 4 cases ,the remain were normal. The signs of chest X ray were classified as the type of pneumonia,the type of chronic bronchitis with acute exacerbation;
    血沉 72 .8±36 .3mm/h,外周血白细胞 >11.0× 10 9/L4例 ,其余正常范围。
短句来源
    Etiology of Acute Exacerbation in Severe Chronic Active Hepatitis
    重型慢性活动性肝炎患者急性加重的病因探讨
短句来源
    RESEARCHES ON THE CAUSES OF ACUTE EXACERBATION IN CHRONIC HEPATITIS B
    慢性乙型肝炎肝病急性加重的原因探讨
短句来源
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  acute exacerbation
Acute exacerbation of COPD is most often caused by pulmonary infections.
      
The term acute exacerbation of chronic obstructive pulmonary disease (COPD) reflects an acute worsening of the stable state with an increase in dyspnea, cough, and count or purulence of sputum.
      
The management of an acute exacerbation is guided mainly clinical severity which has implications on the decision of outpatient management, hospital management or intensive care treatment.
      
If invasive mechanical ventilation is necessary, the potential of dynamic hyperinflation in acute exacerbation has to be considered.
      
Non-invasive ventilation (NIV) has been proposed as an efficient alternative to conventional mechanical ventilation during acute exacerbation of chronic obstructive pulmonary disease (COPD).
      
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Seven cases with triple infection of HAV, HBV and CMV were reported. Acute hepatitis was diagnosed in 1 case, CPH and CAH each in 3. Serum specimens were tested by indirect immunofluores-cence technique for specific IgM antibodies against HAV and CMV, HBV markers were identified by RPHA, SPRIA and ELISA respectively. The clinical course and prognosis of these patients depended mainly on the type of HBV infection. In some cases of chronic hepatitis B superinfection with other viruses seemed to be one of the factors...

Seven cases with triple infection of HAV, HBV and CMV were reported. Acute hepatitis was diagnosed in 1 case, CPH and CAH each in 3. Serum specimens were tested by indirect immunofluores-cence technique for specific IgM antibodies against HAV and CMV, HBV markers were identified by RPHA, SPRIA and ELISA respectively. The clinical course and prognosis of these patients depended mainly on the type of HBV infection. In some cases of chronic hepatitis B superinfection with other viruses seemed to be one of the factors causing deterioration or acute exacerbation.

本文报告7例受甲型肝炎病毒(HAV)、乙型肝炎病毒(HBV)及巨细胞病毒(CMV)三重感染的病毒性肝炎,其中诊断为急性病毒性肝炎1例、慢迁肝和慢活肝各3例。采用间接免疫荧光法检测抗一CMV IgM和抗-HAV IgM,乙肝标志分别用反向被动血凝(RPHA)、固相放免测定(SPRIA)及酶联免疫吸附试验(ELISA)检测。本组病例的临床经过与转归,似乎主要取决于乙肝病毒感染的性质,在部分乙肝病人中重叠感染是导致病情恶化或急性发作的原因。

To explore etiology of acute exacerbation in severe chronic active hepatitis,HBVDNA in situ hybridization was carried out in a group of patients,combined with detection of HBV markers in serum and liver as well as intrahepatic HDAg.Four subgroups were identified based on the etiological evidence.(1) 60.0% cases were still undergoing HBV active replication or reactivation in which HBcAg cytoplasmic and membreneous expression was often associated with the hepatic necrosis foci; (2) in 20% cases with HBsAg...

To explore etiology of acute exacerbation in severe chronic active hepatitis,HBVDNA in situ hybridization was carried out in a group of patients,combined with detection of HBV markers in serum and liver as well as intrahepatic HDAg.Four subgroups were identified based on the etiological evidence.(1) 60.0% cases were still undergoing HBV active replication or reactivation in which HBcAg cytoplasmic and membreneous expression was often associated with the hepatic necrosis foci; (2) in 20% cases with HBsAg or HBVDNA,despite absence of HBcAg expression,membraneous and homogeneous HBsAg expression was also closely related to hepatic necrosis; (3) 13.3% cases were with intrahepatic HDAg; (4) the remaining single case had no HBV infection evidence.All these findings suggest that HBV active replication or reactivation was the major cause of these exacerbation in severe chronic active hepatitis.In addition,HDV superinfection accounted for over 10% exacerbation and hepatitis V and C virus superinfection may contribute to some episodes of exacerbation.

为探讨慢性活动性肝炎患者急性加重的病因,对15例患者进行肝细胞内HBV DNA(乙肝病毒脱氧核糖核酸)原位杂交研究,同时检查血清与肝内HBV标志及肝内HDAg。发现:①60.0%(9/15)患者存在HBV活动性复制或HBV复制重新激活,观察到表达浆膜型HBcAg肝细胞多紧紧毗邻肝细胞坏死灶;②20.0%(3/15)患者肝内HBsAg或(和)HBVDNA阳性,虽无HBcAg表达,但见到浆膜型HBsAg表达或含HBV DNA肝细胞与肝细胞坏死灶关系密切的表现:③13.3%(2/15)患者有HDV二重感染;④1例患者缺乏HBV感染标志。表明慢性活动型肝炎急性加重主要与HBV活动性复制、HBV复制重新激活或HBV感染持续存在有关,其次是HDV二重感染,少数病例可能存在HAV或HCV的重叠感染。

Objective In this study, we evaluated the relationship between HBV DNA serum level and acute hepatic exacerbation of the disease in chronic hepatitis B patients.Methods A series of serum samples from 14 patients of acute exacerbation of chronic hepatitis B were analyzed for alteratieus in serum HBV DNA and alanine transaminase (ALT) level before, during, and after episode of an acute exacerbation. The serum HBV DNA concentrations were tested by the quantitative polymerase chain reaction (PCR) using...

Objective In this study, we evaluated the relationship between HBV DNA serum level and acute hepatic exacerbation of the disease in chronic hepatitis B patients.Methods A series of serum samples from 14 patients of acute exacerbation of chronic hepatitis B were analyzed for alteratieus in serum HBV DNA and alanine transaminase (ALT) level before, during, and after episode of an acute exacerbation. The serum HBV DNA concentrations were tested by the quantitative polymerase chain reaction (PCR) using the AmpliSensor assay.Results ①Serum HBV DNA average levle in 11 patients significantly increased from 7.148±2.008(logarithm) at 2~8 weeks before maximum injury of liver to 8.416±2.160 (logarithm), the time that ALT reached its peak, and then, following the declining of ALT level, decreaed to 6.093±1.428 (logarithm). In 9 of 11 cases, the HBV DNA peak value occurred before the ALT peak level or at the same time; ②Two patients who experienced several episodes of acute exacerbation showed that the appearance of acute hepatic injury and the relatively normal liver function occurred alternatively. Whereas, one patient with liver cirrhosis showed persistence of high level viremia in three episodes of acute exacerbation in one year.Conclusion ①This investigation revealed a clear correlation between increasing level of serum HBV DNA and actue exacerbation of patinets with chronic hepatitis B. The findings suggest that host′s immune response which causes acute exacerbation of liver injury in patients with chronic hepatitis B is triggered by the change of viremia and HBV replication; ②Patients with severe chronic active hepatitis and persistent hepatitis B virus repliation are at very high risk of rapid progression to cirrhosis.

目的 研究慢性乙型肝炎急性发作与血清HBVDNA含量的关系。方法 采用荧光标记(AmpliSensor)定量方法,测定一组自发性反复发作的慢性乙型肝炎患者发作前、中和后的血清HBVDNA含量的变化。结果 ①11例患者中有9例(82%)血清HBVDNA含量的高峰值是在最大肝损害之前出现或与丙氨酸转氨酶(ALT)同时达到高峰。而其余2例的高峰值则出现在恢复期;②测定2例数次发作的慢性乙型肝炎患者的系列血清中HBVDNA,也显示了上述特点。并表现出急性肝损害与正常肝功能交替出现的特征。而另1例肝炎肝硬化多次急性发作中,显示持续高水平的病毒血症。结论 血清HBVDNA含量的变化与大部分慢性乙型肝炎的急性发作有着密切的关系,提示乙型肝炎病毒的复制启动和激发了机体的免疫反应,导致了肝细胞的损伤。

 
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