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potency
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  效价
     The MIC of Compound 2~6 are 0.01~0.1mg/mL, 0.01~0.1mg/mL, 1~2mg/mL, 0.1~1mg/mL, 0.1~1mg/mL, while their antifungal potency are 44.8%, 27.8%, 54.5%, 44.1%, 48.5%.
     化合物2~6的最低抑菌浓度分别为:0.01~0.1mg/mL,0.01~0.1mg/mL,1~2mg/mL,0.1~1mg/mL,0.1~1mg/mL; 抗菌效价分别为:44.8%,27.8%,54.5%,44.1%,48.5%。
短句来源
     Taking crude product of heparin sodium of potency 85 USPu/mgas material,the yield and quality of product of the H_2O_2-H_2O_2 double oxidationprocess were superior to the KMaO_4-H_2O_2 double oxidation process.
     以生物效价85USPu/mg 的肝素钠粗品为原料,H_2O_2-H_2O_2两次氧化工艺的产品收率及质量优于 KMnO_4-H_2O_2复合氧化工艺。
短句来源
     LTLT(63 ℃ ,30min)and HTST(85℃ ,15s)pasteurization made the Nisin potency decrease to 86.82%and 98.2%,UHT(115℃ 10min, 130℃2s )sterilization made the Nisin potency decrease to 3.43% and 80.58%.
     采用LTLT(63℃ 30min)和HTST(85℃15s)巴氏杀菌,其效价分别下降到86.82%、98.2%,采用UHT(115℃ 10min、130℃2s)灭菌其效价分别下降到3.43%、80.58%。
短句来源
     In normal situation, the potency in salt hydrolytic solution of porcine intestinal mucosa was about 60000 u per set of small intestine, the heparin adsorption rate of resin was 79.6%~84.0%, the yield rate in eluent 77.1%~81.8% and in ethanol precipitate 80.9%~85.7%.
     正常情况下 ,猪肠粘膜的盐解液效价约为 6 0 0 0 0 u/副小肠 ,树脂吸附率为 79.6 %~ 84.0 % ,洗脱液得率 77.1%~ 81.8% ,乙醇沉淀物收率 80 .9%~ 85 .7%。
短句来源
     and the potency was increased to(l79.0 ± 0. 8 ) uspu' mg-1 from(168. 7 ± 2. 4 ) uspu' mg-1 (both of them P < 0. 0l ).
     效价由传统工艺的(168.7±2.4)uspu·mg-1提高到(179.0±1.8)uspu·mg-1。 与传统工艺比较,经t检验,回收率和效价P值均<0.01。
短句来源
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  效力
     After purification by column chromatography,the removal rate of foreign protein reached more than 99.95%. The total protein,DNA and GP contents of final bulk were not more than 80 μg,not more than 10 pg and 3.5~4.5 IU respectively,and its potency was not less than 4.5 IU/0.5 ml.
     经柱层析纯化,杂蛋白去除率达99.95%以上,总蛋白含量≤80μg/g,DNA含量≤10pg/0.5ml,GP含量3.5~4.5IU/0.5ml,效力≥4.5IU/0.5ml。
短句来源
     Potency Test for A Fowl Cholera Live Vaccine (G190E_(40) strain ) in mice
     以小鼠检测鸡霍乱G190E_(40)疫苗的效力试验
短句来源
     The average potency to FMDV types O,A,and AsiaⅠ were 4.73 PD_(50)/dose,6.84 PD_(50)/dose and 8.10 PD_(50)/dose,respectively.
     对O、A、AsiaⅠ型口蹄疫的平均免疫效力分别为4.73、6.84和8.10 PD50/头份;
短句来源
     Objective To develop a method for determining the potency of heat shock protein 65-MUC1 antigen peptide fusion protein(HSP65-MUC1).
     目的建立热休克蛋白65(HSP65)MUC1抗原肽(HSP65MUC1)融合蛋白的效力测定方法。
短句来源
     The neutralizing antibldy titer of mice immunized with live and inactivated JE vaccine were 1:5 and 1:20 respectively , and the immune potency of the 2 kinds of vaccine were 3.6×10 -6 and 4.0×10 -4 -4.2×10 -4 ID 50 /ml , respectively.
     用同批活疫苗免疫小鼠后其中和抗体效价为 1:5 ,而同批的灭活疫苗为 1:2 0 ,活疫苗的免疫效力 (ID5 0 ) 3 6× 10 6(ml)显著高于灭活疫苗的 4 0× 10 - 4 ~ 4 2× 10 4(ml)。
短句来源
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  潜能
     Potency of Induced Differentiation in vitro of A Human Promyelocytic Leukemia Cell Mutant (HL-60-AR) with Characteristics of Resistance to 8-AG and Deficiency in HGPRT
     抗8-AG和HGPRT缺失的人早幼粒白血病细胞突变株(HL-60-AR)的体外诱导分化潜能
短句来源
     The Correlation between L-selectin and P388D1 Cell Line Metastasis Potency to Peripheral Lymph Nodes
     L-选择蛋白与P388D1淋巴瘤细胞淋巴道转移潜能的相关性
短句来源
     Study on the development potency of 1/8 blastomeres of mouse early embryos
     小鼠早期胚胎1/8分裂球发育潜能的研究
     Nm23-H1 maybe a upstream controlling gene to metastasis related gene, and implement it's depressant effect to metastasis potency of tumor by downstream gene.
     据推测nm23-H1基因可能仅为转移相关基因的上游调节基因,它对肿瘤转移潜能的抑制作用是通过下游基因实现的。
短句来源
     Conclusion: Both the telomerase related with cell proliferation and CD44 v5/v6 in relation with tumor metastasis closely correlate with the malignancy and metastasis potency of ovarian cancer, and there is a close correlation between them.
     结论:肿瘤细胞增殖活性相关的端粒酶活性和肿瘤转移相关的CD44v5、v6都与卵巢癌的恶性程度及转移潜能密切相关,且二者之间存在相关性。
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  “potency”译为未确定词的双语例句
     The Gene Construction,Expression and Anti-tumor Potency of Targeted Recombinant Caspase-3
     靶向性重组caspase-3基因的构建、表达及其对肿瘤细胞的杀伤作用
短句来源
     Study of the Difference in Anti-proliferative Potency of a New Thymidylate Synthase Inhibitor Nolatrexed and Its Mechanism
     新型胸苷酸合成酶抑制剂洛拉曲克抗增殖作用的差异及其机理的研究
短句来源
     Comparative Potency of Seven Compounds Isolated from Tripterygium Wilfordii on Cultred Rat Leydig Cells and Sertoli Cells
     Comparative Potency of Seven Compounds Isolated from Tripterygium Wilfordii on Cultred Rat Leydig Cells and Sertoli Cells
短句来源
     The Expression of the Glycoprotein Gene of Chinese Rabies Virus Vaccine Strain(5aG) in Vaccinia Virus and Its Immune Potency in Mice
     中国狂犬病毒疫苗株(5aG)糖蛋白基因在痘苗病毒中的表达及免疫效果观察
短句来源
     Application and comparison of three methods in evaluating the potency of psychic dependence
     三种精神依赖性评价方法的比较及应用
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  potency
The study showed that the introduction of a pyrazole ring on pyridazinone led to a marked decrease in AR inhibitory potency.
      
The multiple antioxidant activity of the polysaccharides was evidenced by significant reducing power, superoxide scavenging ability, inhibition of mice erythrocyte hemolysis mediated by peroxyl free radicals, and also ferrous ion chelating potency.
      
The data obtained in the in vitro models clearly establish the antioxidant potency of the polysaccharides extracted from Lyceum barbarum fruits.
      
The models could be usefully employed to design inhibitors with greatly enhanced potency and selectivity.
      
The ADM can be used as an accessory marker in estimating the malignant potency of LE and judging the prognosis of LES, and as a novel molecular target of anti-angiogenic and anticarcinogenic strategies.
      
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A new method for the biological assay of vegetable purgatives based on the numbers of wet faeces excreted by groups of mice after dosing is described. The relation of the number of wet faeces per group of mice to the logarithm of the dose was found to be linear. A cage has been specially designed for this assay and it has been found advantageous to incorporate a definite proportion of water in the diet during test. 40 mice divided equally into 4 groups were used in each assay. 2 groups received the standard...

A new method for the biological assay of vegetable purgatives based on the numbers of wet faeces excreted by groups of mice after dosing is described. The relation of the number of wet faeces per group of mice to the logarithm of the dose was found to be linear. A cage has been specially designed for this assay and it has been found advantageous to incorporate a definite proportion of water in the diet during test. 40 mice divided equally into 4 groups were used in each assay. 2 groups received the standard preparation and the other 2 groups received the test preparation. The standard deviation of a single determination based on 9 such assays was estimated to be 15.7 per cent. For rhubarb and its preparations, a“6-point”assay is advocated. With suitable restric-tion in the design of the assay, it is possible to calculate the potency by simple methods. Powdered crude drugs are used as laboratory standards in the assay of senna and rhubarb. The doses of cascara bark required to produce distinctive responses are too inconveniently large to be administered in suspension. It was found possible to use a potent extract of cascara in place of the powdered bark as a laboratory standard. Examples of the assay and the subsequent calculations are given. The method described is not only convenient in use but also gives a comparatively high degree of accuracy. The method has been successfully applied to senna leaf, senna fruit, rhubarb, cascara sagrada and extracts and commercial preparations made from these drugs, pure glycosides(sennosides A and B) and pure anthracene compounds(aloe emodin and aloe-emodine anthranol).

(1)本文详述植物性泻药的一种新的生物测定法,此法係用小白鼠在服药后所排出的濕粪数为基础,以定泻药的效价。(2)小白鼠服药後所排出的湿粪数与剂量指数的关係经证明为一直线。(3)本法所用鼠笼係特别设计,并证明在饲料内加入一定量的饮水,具有多种优点。(4)番泻效价的测定,每次用小白鼠4组,每组10只。2组给与标准品,另外2组给与试验品。根据9次试验的结果,试验的标准差是15.7%.(5)大黄效价的测定,以采用“6点”法为宜,即每次试验用小白鼠6组,3组给与标准品,另外3组给与试验品,所得的准确度与上述相仿。波希鼠李皮浸膏的效价测定,则用“4点”法或“6点”法均可。(6)所有试验一律采用粉状生药为实验室的比较标准,但是波希鼠李皮的效价太低,它的粉末不适於作为标准之用,可用波希鼠李皮乾浸膏来代替,作为比较标准。(7)本文对於效价测定及其计算方法都举例说明,并介绍了比较常法为简捷的相关效价计算法。(8)本法不但方便易行,而且有相当高的准确度;曾用在番泻、大黄、波希鼠李皮及其制剂,以及一些纯粹的蒽醌衍生物的效价测定,都获得了满意的结果。

An experimental study of 300 mice exposed to pitch(3 gm.dissolved in 10 ml.of 80% benzene solution)obtained from 4 different sources,name- ly Anshan coal-tar pitch,Yu-men petroleum pitch,Dairen petroleum pitch or commonly known as Russian crude oil and the Asia Oil Company, USA,was carried out over a period of 350 days. From the beginning a group of these experimen- tal animals was exposed to artificial sun-ray for 2 hours a day.The results of our experiment indicate that pathological changes of different degrees...

An experimental study of 300 mice exposed to pitch(3 gm.dissolved in 10 ml.of 80% benzene solution)obtained from 4 different sources,name- ly Anshan coal-tar pitch,Yu-men petroleum pitch,Dairen petroleum pitch or commonly known as Russian crude oil and the Asia Oil Company, USA,was carried out over a period of 350 days. From the beginning a group of these experimen- tal animals was exposed to artificial sun-ray for 2 hours a day.The results of our experiment indicate that pathological changes of different degrees of severity,such as chronic dermatitis and tumor formation,were the commonest effect of pitch on skin both in the exposed and non-ex- posed groups while the control group(exposed to 80% benzene only)showed only slightly acute dermatitis. The pathological changes as observed both in gross appearances and histological findings are given in detail. The course of tumor formation as found in both the exposed and the non-exposed groups may be classified in the order of time sequence as benign squamous papilloma,malignant squamous papilloma and finally squamous-celled carcinoma; also a few cases of sarcoma and a few cases of so- called“Myoblastoma”. Through the action of photosensitivity to the exposed group,the prolongation of the latent period of tumor formation,the effectiveness in the development of dermatitis and malignant changes in tumors were clearly observed in the process of the pathological changes. The relative potency of the carcinogenic pitch obtained from the above sources has been calculated by means of the statistical analysis of both the incidence and the length of time for the development of the cutaneous tumors.

(一)四种来源不同的沥青(鞍山煤焦油沥青、西北玉门石油沥青、大连石油沥青、和美国亚细亚公司石油沥青)经涂抹小白鼠的实验证明具有引起皮肤各种的病理变化的作用。其中包括慢性渗出性皮炎;慢性炎性上皮结缔组织增生;良性皮肤乳头状瘤;皮肤鳞状细胞癌。此外也引起了少数的肉瘤和“肌母细胞痛”。皮肤瘤发生的潜伏期由62天至406天不等。(二)光感作用可以加剧及加速煤焦油沥青皮肤炎的进展,和发炎皮肤的角化现象。至于对沥青致癌作用本实验未能证实其有显著的影响。(三)根据四种来源不同的沥青所引起皮肤良性与恶性病变的发病率和潜伏期的长短,可将其毒性的强弱顺序排列如下:(1)鞍山煤焦油沥青,(2)美国亚细亚公司石油沥青,(3)大连石油沥青(苏联原油),(4)西北玉门石油沥青。即煤焦油沥青毒性远较石油沥青为强。国产石油沥青的毒性较外产石油沥青的毒性为弱。

1.Twenty-two agents were tested in vitro, and four of them also in vivo for their antituber- culous activity. 2.Ginkgolic.acid,the active principle of ginkgo fruit against tubercle bacilli,was found to exist only in the fleshy part(endocarp)of the fruit.The tuberculostatic action of ginkgolic acid in vitro was not influenced by heating,but the presence of serum raised the minimal effec- tive concentration from 1:400,000 to 1:1000.The results of in vivo tests failed to demonstrate any effect of the different...

1.Twenty-two agents were tested in vitro, and four of them also in vivo for their antituber- culous activity. 2.Ginkgolic.acid,the active principle of ginkgo fruit against tubercle bacilli,was found to exist only in the fleshy part(endocarp)of the fruit.The tuberculostatic action of ginkgolic acid in vitro was not influenced by heating,but the presence of serum raised the minimal effec- tive concentration from 1:400,000 to 1:1000.The results of in vivo tests failed to demonstrate any effect of the different parts of ginkgo fruit in- cluding ginkgolic acid on the experimental tuber- culosis of mice.No apparent difference was found between the activity of ginkgo fruit with or without previous preparation with vegetable oil. 3.(?)In vitro,garlic exhibited rather weak tuberculostatic action,which decreased slightly in thè presence of serum.The in vitro effect of the winter garlic was better than that of the spring one.No curative effect was exerted by garlic on the experimental tuberculosis of mice. 4.The minimal tuberculostatic concentra- tion of berberine in vitro was found to be around 1:4000,and the èffect slightly decreased in the presence of serum.The development of experi- mental tuberculosis of mice was delayed by the administration of berberine sulfate in daily oral doses of 1.5—2.5 gm./kg. 5.There was definite curative effect of stepharanthine on the experimental tuberculosis of mice in daily doses of 200 mg./kg.;significant toxicity appeared,however,at that dosage level. 6.No significant tuberculostatic effect in vitro was found among other crude drugs. 7.“Hei pao”was ineffective in vitro,while citrinin was definitely effective and its minimal tuberculostatic concentration determined as 1:20.000. 8.Amon synthetic compounds tested,the in vitro tuberculostatic potency of an isomer of PAS was only one-hundredth of that of sodium para- amino-salicylate.The tuberculostatic effects of four sulfones were not satisfactory.The minimal tuberculostatic concentration in vitro of syn- thotic compound Ⅵ was 1:200,000. 9.It was found that the effectlve ranges of the concentration and dosage of thiosemicarba- sone in viro and in vivo were very broad,and the lower margins were comparable with those of isonicotinyl hydrazine.These facts may explain the elinieal effectiveness of thiosemicarbazone used in small doses.

1.在玻器内试验了22种药物,在动物体内试验了四种药物的抗结核杆菌作用。2.白果的抗结核杆菌有效成分(白果酸)仅存在于白果果浆中。白果酸在玻器内的抗菌作用不受加热的影响;但血清能使其最低有效浓度从1:400,000跃至1:1000。白果各部分及白果酸对小鼠的实验结核症并无肯定的疗效。油浸过的白果与未浸过的作用并无显著不同。3.大蒜在玻器内具有较弱的抗结核杆菌作用,遇血清则效力略减;冬季大蒜比春季大蒜的效力高。对小鼠的实验结核症并无疗效。4.黄连硷在玻器内的最低抑制结核杆菌浓度是1:4000左右,遇血清则效力略减。每日食入硫酸黄连硷约1.5—2.5克/公斤时,可以延缓小鼠实验结核症的发展。5.使他肺安定每日200毫克/公斤时,对小鼠实验结核症有肯定的疗效,但已表现相当大的毒性。香豆素在玻器内当浓度为1:2000时有部分抗结核杆菌作用。6.其他生药中,仅韭菜及青蒜在修改的都氏培养基中具有微弱的抗结核杆菌能力,但在尤氏培养基中无效。7.海宝在玻器内无效,橘霉素的最低制菌浓度是1:20,000。8.所试的化学合成品中,对氨水杨酸的同质异构物的抗结核杆菌作用仅为对氨水杨酸钠的1/100。砜类化合物的抗结核杆菌作用很微弱...

1.在玻器内试验了22种药物,在动物体内试验了四种药物的抗结核杆菌作用。2.白果的抗结核杆菌有效成分(白果酸)仅存在于白果果浆中。白果酸在玻器内的抗菌作用不受加热的影响;但血清能使其最低有效浓度从1:400,000跃至1:1000。白果各部分及白果酸对小鼠的实验结核症并无肯定的疗效。油浸过的白果与未浸过的作用并无显著不同。3.大蒜在玻器内具有较弱的抗结核杆菌作用,遇血清则效力略减;冬季大蒜比春季大蒜的效力高。对小鼠的实验结核症并无疗效。4.黄连硷在玻器内的最低抑制结核杆菌浓度是1:4000左右,遇血清则效力略减。每日食入硫酸黄连硷约1.5—2.5克/公斤时,可以延缓小鼠实验结核症的发展。5.使他肺安定每日200毫克/公斤时,对小鼠实验结核症有肯定的疗效,但已表现相当大的毒性。香豆素在玻器内当浓度为1:2000时有部分抗结核杆菌作用。6.其他生药中,仅韭菜及青蒜在修改的都氏培养基中具有微弱的抗结核杆菌能力,但在尤氏培养基中无效。7.海宝在玻器内无效,橘霉素的最低制菌浓度是1:20,000。8.所试的化学合成品中,对氨水杨酸的同质异构物的抗结核杆菌作用仅为对氨水杨酸钠的1/100。砜类化合物的抗结核杆菌作用很微弱。合成品〔Ⅵ〕的最低制菌浓度是1:200,000。9.硫脲胺的部分制菌浓度范围和其对小鼠实验结核症有效剂量的范围都很广,可以追及异烟肼的水平,这可解释临床上其剂量很小,但仍能生效的原因。

 
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