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hypothermia
相关语句
  低温
    Influence of methylprednisolone on serum S-100 beta protein after deep hypothermia cerebral ischemia reperfusion in rats
    甲泼尼龙对深低温脑缺血再灌注大鼠血清S-100β蛋白的影响
短句来源
    Like hypothermia,scopolamine can protect Na +-K +-ATPase activity in the cerebral cortex during postischemic reperfusion,but hypothermia has no cooperating effect on scopolamine.
    东莨菪碱和低温一样 ,能保护缺血后再灌注脑组织Na+ -K+ -ATPase活性 ,但东莨菪碱和低温无明显的协同作用
短句来源
    Results In group 2.2% Enf, ATP content was significantly higher and the activity of Na+ -K+ ATPase was significantly lower than those in group 1. 1 % Enf at normothermia or hypothermia (P < 0. 05 or 0. 01 );
    结果常温或低温下, 2. 2% Enf组 ATP含量明显高于 1. 1% Enf组,Na+-K+ATPase活性明显低于1.1% Enf组(P<0.05或0.01);
短句来源
    but ADP content and EC in group 2. 2 % enflurane were obviously higher and activity of Ca2+ ATPase was lower than those in group 1. 1 % Enf at hypothermia (P < 0. 05 or 0. 01 ).
    而低温下,2.2% Enf组ADP含量及EC明显高于1.1% Enf组,Ca2+ATPase活性明显低于1.1% Enf组(P<0.05或0.01)。
短句来源
    Hearts for all groups were subjected to 4 h hypothermia (4 ℃) and 40 min reperfusion (37 ℃).
    心脏低温(4℃)保存4h后,再灌注40min(37℃)。
短句来源
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  低体温
    Effects of Hypothermia on Pulmonary Hemodynamics and Plasma Levels of Norepinephrine, Serotonin(5-HT), Thromboxane A_2 and Prostacyclin
    低体温对肺循环和血浆去甲肾上腺素、5-羟色胺、血栓素A_2、前列环素的影响
短句来源
    The concentrations of both TxB2 and 6-keto-PGF1αdid not change during hypothermia.
    低体温不影响动脉血中TxB_2(TxA_2稳定代谢产物)和6-keto-PGFlα(PGI_2稳定代谢产物)的水平。
短句来源
  降温
    RESULTS: Administration of the soman (60 μg·kg -1 , sc) led to a rapid reduction in body temperature. Administration of scopolamine (1 mg·kg -1 , ip) marke dly blocked the hypothermic effec t of soman but administration of methyl scopolamine (1 mg·kg -1 , ip) had n o effect on the hypothermia.
    结果 :皮下注射梭曼 (60 μg·kg- 1)后可引起体温快速的降低 ,腹腔注射东莨菪碱 (1mg·kg- 1)可明显阻断梭曼的降温作用 ,注射甲基东莨菪碱 (1mg·kg- 1)对其降温作用无明显影响。
短句来源
    Repeated administration with AG (10,20,40,80mg·kg -1,ig for 1 time per day for 7d)had no significant effect on the apomorphine(16mg·kg -1 ip)induced hypothermia or this AUC_ 0~30 in mice.
    在小鼠RES诱导体温下降实验模型上,ig给予AG10~80mg·kg-1(qd,连续7d),对RES1mg·kg-1诱导的降温和AUC0~6均有显著的拮抗作用。
短句来源
    Effect of cholinergic antagonist on soman-induced hypothermia in the rat
    胆碱能阻断剂对梭曼引起大鼠降温效应的影响(英文)
短句来源
    It has been observed that trilobine can inhibit automatic action of mice, strengthen inhibition by sodium pentobarbital or chloral hydrate on the central nervous system, antagonize excitation by caffeine and amphetamine, delay the incubation period of eclampsia by pentylenetetrazol and strychnine,and prolong the survival time of the mice convulsed by strychnine. Moreover, trilobine is possessed of analgesia and hypothermia, showing its inhibition on the central nervous system
    本文观察到Tr具有抑制小鼠的自主活动,加强戊巴比妥钠及水合氯醛对中枢的抑制作用,拮抗咖啡因与苯丙胺的兴奋作用,推迟出现戊四氮和士的宁惊厥的潜伏期,延长士的宁致小鼠惊厥后死亡的时间,本品尚有镇痛和降温作用,表明Tr具有镇静、镇痛、降温等中枢抑制作用。
短句来源
    In observed group,O 2 and ERO 2 decreased and S O 2 increased significantly at the beginning of hypothermia and during rewarming,ABL after rewarming was significantly lower in test group than that in control group.
    (2 )组内S VO2 复温后下降 ,ABL增加 ,与最低温时比较差异非常显著 (P <0 0 1) ; 观察组S VO2 在降温开始及复温后显著高于对照组 (P <0 0 5 ) ,ABL复温后显著低于对照组 (P <0 0 5 )。
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  “hypothermia”译为未确定词的双语例句
    In contrast, plasma level of 5-HT decreased markedly during hypothermia, and the metabolic product of 5-HT, 5-hydroxyindoleacctic acid ( 5-HIAA ) , was no correspondent increment.
    与此相反,血浆中5-羟色胺(5-HT)含量显著减少,其代谢产物5-羟吲哚乙酸(5-HIAA)没有相应增加;
短句来源
    scopolamine and reperfusion with hypothermia(GroupⅥ). RESULTS:Na +-K +-ATPase activity in the cerebral cortex is the lowest in groupⅢ; but it was greater in group Ⅱ, Ⅳ, Ⅴ, Ⅵ than groupⅢ( P <0.05 or P <0.01), which was not significantly difference from groupⅠ( P >0 05);
    Ⅱ、Ⅳ、Ⅴ、Ⅵ组的Na+ -K+ -ATPase活性显著高于Ⅲ组 (P分别 <0 0 5或 <0 0 1) ,与Ⅰ组无显著差异 (P >0 0 5 )。
短句来源
    Time- and dose- dependent development of tolerance to the hypothermia induced hy
    烟碱诱发大鼠体温下降形成耐受的时间与剂量依赖性
短句来源
    Modulation of central nicotinic receptor on muscarinic receptor-mediated hypothermia
    中枢N受体对M受体介导体温降低作用的调节
短句来源
    Sexual differences of organophosphate pesticide chlorpyrifos-induced hypothermia in the rat and the relationship with gonadal function
    有机磷杀虫剂毒死蜱引起大鼠低温的性别差异与性腺的关系
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  hypothermia
Cooling strategies and transport theories for brain hypothermia resuscitation
      
Under such adverse situations, the potential for cerebral protection through hypothermia has been intensively investigated in clinics by lowering brain temperature to restrain the cerebral oxygen demands.
      
It is now clear that hypothermia would serve as the principal way for neurologic protection in a wide variety of emergency medicines, especially in cerebral damage, anoxia, circulatory arrest, respiratory occlusion, etc.
      
Compared with the expanded trials in clinics, only very limited efforts were made to probe the engineering issues involved, which turns out to be a major obstacle for the successful operation of brain hypothermia resuscitation.
      
Aiming to provide a complete overview of the brain hypothermia resuscitation, this article comprehensively summarizes the recent progresses made in theoretical, practical and experimental techniques in the area.
      
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(1) In mice, intraperitoneal injection of corydalis B (dl-tetrahydropalmatine), 40 mg/kg, potentiated hexobarbital narcosis, and reduced the passive and spontaneous activity in the rotarod, rolling cylinder and photo-electric cage experiments. The hyperactivity induced by small doses of amphetamine and the amphetamine toxicity in aggregated mice were both significantly reduced by this drug. On the motor defense conditioned reflexes in.cat corydalis B had no marked influence in subcutaneous doses of 10—20 mg/kg....

(1) In mice, intraperitoneal injection of corydalis B (dl-tetrahydropalmatine), 40 mg/kg, potentiated hexobarbital narcosis, and reduced the passive and spontaneous activity in the rotarod, rolling cylinder and photo-electric cage experiments. The hyperactivity induced by small doses of amphetamine and the amphetamine toxicity in aggregated mice were both significantly reduced by this drug. On the motor defense conditioned reflexes in.cat corydalis B had no marked influence in subcutaneous doses of 10—20 mg/kg. At the dosage of 30 mg/kg, the cats exhibited at first excitant behavior (running, jumping, growling etc.) and then depression set in with almost complete disappearance of conditioned and unconditioned reflexes. At the intraperitoneal dosage of 10 mg/kg, the conditioned reflex was abolished partially, whilst the unconditioned reflex remained unaffected. In cats, an intraventricular injection of corydalis B, 1—2 mg/kg, caused changes in aggressive behavior, such as hissing. The cats became calm and drowsy, but could be easily awaken by external stimuli. In normal rabbits, spontaneous electric activity of cerebral cortex was recorded. The low voltage fast activity was the main element in EEG, sometimes α-wave and spindles were presented. Within 3—7 minutes following single intravenous injection of 15—20 mg/kg, the high voltage slow waves (1.5—3 c/s, 250—400 μv) were found, and maintained 5—15 minutes.. At the same time the arousal response in EEG evoked by stimulation on skin with direct current was inhibited. Thereafter, in the lapse of 20—40 minutes, EEG recovered gradually. (2) In mice, corydalis B aggravated the strychnine convulsions, but inhibited the metrazol convulsions. It had some synergetic action with phenytoin. (3) A single subcutaneous injection of 40 mg/kg of corydalis B could antagonize emesis induced by 0.1—0.2 mg/kg of apomorphine, but failed to do so when the dosage of the latter was raised to 1 mg/kg. The emesis caused by copper sulfate was not antagonized by corydalis B. (4) In rats, corydalis B produced a slight hypothermia.

(一)延胡索素乙与环己烯巴比妥钠有协同作用,可以减低小白鼠的被动性和自发性活动;它能对抗小量苯丙胺的兴奋现象,又能明显降低大剂量苯丙胺的毒性反应。它们的有效剂量为20—40毫克/公斤。皮下注射乙素10—30毫克/公斤可使猫先兴奋后抑制,较大剂量对防御性条件反射和非条件反射均能抑制,该作用持续2—3小时以上;腹腔给药时作用情况相似。从侧脑室注射乙素1—2毫克/公斤可使猫消除恐惧跳避的行为,出现瞌睡现象,但易为外界刺激所唤醒。正常家兔的皮层脑电波以低电压快波为主,静脉注射乙素15—20毫克/公斤可使其变成高电压慢波,此时对感应电流刺激皮肤的惊醒反应明显消灭,约历40分钟乙素作用消失。 (二)乙素可使士的宁容易产生惊厥,伹能抑制五甲烯四氮唑的惊厥作用。它不能对抗电休克的发生,略能协同苯妥英钠作用。 (三)乙素略有中枢性的镇吐作用,略能降低体温。

When chronically reserpinized, the mice suffered from weight loss, emaciation, diarrhea, prolapse of the anus, hypothermia, hypophagia, decrease of metabolic rate and spontaneous locomotor activity. After giving "si jun zi tang" some of these symptoms were alleviated. The effect of ACh on the isolated ileum of reserpinized mice was hypersensitivity. The slope of the response curve of the dosage was markedly elevated. After giving "si jun zi tang", the ileum response to ACh was markedly decreased and returned...

When chronically reserpinized, the mice suffered from weight loss, emaciation, diarrhea, prolapse of the anus, hypothermia, hypophagia, decrease of metabolic rate and spontaneous locomotor activity. After giving "si jun zi tang" some of these symptoms were alleviated. The effect of ACh on the isolated ileum of reserpinized mice was hypersensitivity. The slope of the response curve of the dosage was markedly elevated. After giving "si jun zi tang", the ileum response to ACh was markedly decreased and returned to normal.The activity of AChE in the blood of reserpinizied mice was elevated to some extent, Afte giving "si jun zi tang" the activity was somewhat decreased but not so distinctly.

慢性利血平化小鼠表现为体重减轻、腹泻、脱肛、体温低下、摄食量减少、能量代谢降低以及自由活动减少。服四君子汤后能改善这些症状。利血平化小鼠离体迴肠对ACh呈现异常高的敏感性。其剂量反应曲线的斜率显著增大。服四君子汤后迴肠对ACh的反应性即显著降低,恢复到正常水平。利血平化小鼠血中胆碱酯酶活性有所增高。服四君子汤后其活性有些降低,但不很显著。

A series of(25)N-phenyl piperazine derivatives was screened for tranquillizing and adrenolytic actions. Compound(25), 1-(3,4,5-trimethexy phenethyl)-4-(p-chloro-phenyl) piperazine was found to be the most active. This compound was active in the following tests in addition to preliminary screening: anti-mescaline, anti-amphetamine toxicity in grouped mice, catalepsy and ptosis, hypothermia, potentiation of morphine analgesia, anti-emetic and Rhesus monkey taming. Gompound(25) also showed a pronounced α-adrenoreceptor...

A series of(25)N-phenyl piperazine derivatives was screened for tranquillizing and adrenolytic actions. Compound(25), 1-(3,4,5-trimethexy phenethyl)-4-(p-chloro-phenyl) piperazine was found to be the most active. This compound was active in the following tests in addition to preliminary screening: anti-mescaline, anti-amphetamine toxicity in grouped mice, catalepsy and ptosis, hypothermia, potentiation of morphine analgesia, anti-emetic and Rhesus monkey taming. Gompound(25) also showed a pronounced α-adrenoreceptor blocking action and certain cardiovascular effects.

在25个N-苯基哌嗪衍生物中,化合物(25),1-(3,4,5-三甲氧基苯乙基)-4-(对氯-苯基)哌嗪安定作用及抗肾上腺素能作用最强。并能引起心率减慢,血压下降,对心电图也有一定的影响。对心血管方面的作用可作进一步研究。

 
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