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   cyclosporine 在 药学 分类中 的翻译结果: 查询用时:0.201秒
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cyclosporine
相关语句
  环孢菌素
    Determination of cyclosporine A in whole blood using liquid-solid extraction by high performance chromatograph
    液-固萃取高效液相色谱测定全血环孢菌素A
短句来源
    RETAKDATION OF HUMAN DRUG-RESISTANT HL-60 CELL IN G_1 PHASE AND INDUCTON OF SENSITIVE CELL TO APOPTOSIS BY CYCLOSPORINE A
    环孢菌素A阻断人HL-60抗药性细胞于G_1期而诱导敏感细胞凋亡
短句来源
    A CASE OF WHOLE BLOOD CONCENTRATIONMONITORING OF CYCLOSPORINE A AFTERHEART TRANSPLANTATION
    心脏移植术1例的环孢菌素A全血浓度监测
短句来源
    PREPARATION OF CYCLOSPORINE A IMMUNOGEN
    环孢菌素A人工抗原的制备
短句来源
    Uptake of cyclosporine A loaded colloidal drug carriers by mouse peritoneal macrophages in vitro
    小鼠腹腔巨噬细胞对环孢菌素A胶体型药物载体的体外摄取(英文)
短句来源
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  环孢素
    The Inhibitory Effect of Tea Polyphenols on the Expression of TGF-βl and Cell Apoptosis in Cyclosporine A-induced Chronic Nephrotoxicity
    抗氧化剂茶多酚对环孢素A诱导慢性肾毒性作用时转化生长因子-β1表达和细胞凋亡的影响
短句来源
    ORAL CYCLOSPORINE PHARMACOKINETICS IN RENAL TRANSPLANTATION PATIENTS
    肾移植病人口服环孢素的药代动力学
短句来源
    The clinical significance of the cyclosporine concentration ratio in the patients of renal transplantation determined by FPIA and HPLC
    FPIA和HPLC法测定肾移植病人环孢素浓度比值的临床意义
短句来源
    A Modified High Performance Liquid Chromatographic Method for Measuring Cyclosporine A Blood Concentration
    高效液相色谱法测定环孢素 A 血药浓度
短句来源
    Influence of cyclosporine concentrations on hepatic function
    肝功能对环孢素血药浓度影响的监测
短句来源
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  环孢霉素
    Pharmacokinetics and Bioavailability of Cyclosporine A Tablet in Dog
    环孢霉素A片剂和口服液在狗体内的药代动力学及相对生物利用度研究
短句来源
    Pharmacokinetic Study of Cyclosporine A in Patients Receiving Transplantation of Human Embryo Adenohypophysial Cells
    人胚腺垂体移植病人环孢霉素药代动力学研究
短句来源
    Progress in the mechanisms of chronic nephroxicity caused by cyclosporine A
    环孢霉素A慢性肾毒性机制研究进展
短句来源
    Determination of cyclosporine A in whole blood by RP-HPLC
    反相高效液相色谱法测定全血中环孢霉素A
短句来源
    In Vitro Effect of Fluoroquinolones on Cyclosporine A Metabolism in Human Liver Microsomes
    氟喹诺酮类药物在人肝微粒体对环孢霉素A代谢影响的研究
短句来源
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  “cyclosporine”译为未确定词的双语例句
    Combination of mycophenolate mofetil with cyclosporine A and methotrexate as acute GVHD prophylaxis after unrelated donor allogeneic bone marrow transplantation
    霉酚酸酯联合CsA和短程MTX预防非亲缘异基因骨髓移植的急性GVHD
短句来源
    And the effects of XGD-1 combined with cyclosporine A(CsA) on the proliferation of T-lymphocytes and the expression of IL-2R were also investigated.
    同时观察了联合应用CsA和XGD-1对细胞增殖与IL-2R表达的影响。
短句来源
    So it is vital to monitor cyclosporine concentration in whole blood regularly. SELEX(Systematic Evolution of Ligands by Exponential Enrichment),is also known as a new selection technique in vitro.
    SELEX技术即配体指数富集的系统进化技术(Systematic Evolution of Ligands by Exponential Enrichment,SELEX),是一种新型的体外筛选技术。
短句来源
    SRIA. Their linear correlation coeffcientwere 0.92 and 0.88 respectively. There was significant difference between TDx and NSRIA at 4h af-ter administration of cyclosporine.
    结果表明:TDx与NSRIA、SRIA均有较好的线性关系(相关系数分别为0.92和0.88),TDx与NSRIA之间仅在眼药后4h点有非常显著差异(p<0.01);
短句来源
    Cyclosporine was established. H5ODS C-18 column (column temperature 60 C ) was detected at 210 nm using alcohol-water (60 : 40,v/v) as mobile phase.
    固定相为H_5ODSC_(-18),乙醇-水(60:40,v/v)作流动相。
短句来源
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  cyclosporine
The cyclosporine-A-sensitive mitochondrial permeability transition pore in winter wheat at a low temperature and under oxidative
      
Induction of apoptosis by HCA was partially prevented by BAPTA, N-acetylcysteine or cyclosporine A.
      
The study included 25 RT patients (mean 5.4±2.7 yrs after the transplantation, 10 females and 15 males) treated with immune suppressive therapy including cyclosporine A, azathioprine and prednisolone.
      
The edeines analogs were tested in several in vitro and in vivo assays using the mouse model, with edeine B (peptide W1) and cyclosporine A as reference compounds.
      
Expression of TNF-α in monocytes/macrophages was significantly reduced after pretreatment of pigs with cyclosporine or dexamethasone.
      
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13 Alhino guinea pigs were experimented upon.5 animals each for GroupsA, B,and 3 for Group C,group A and B were immunized by bovine lens protein. The lenses were disrupted afterwards,then group A animals were injected subeutaneously with normal saline and group B with eyclosporine.The results was that group A developed sympathetic ophthalmia,group B and grouP C could not develop sympathetic ophthalmia.As cyclosporine is a selective suppressive drug to T lymphoeyte the authors suppose that the pathogenesis...

13 Alhino guinea pigs were experimented upon.5 animals each for GroupsA, B,and 3 for Group C,group A and B were immunized by bovine lens protein. The lenses were disrupted afterwards,then group A animals were injected subeutaneously with normal saline and group B with eyclosporine.The results was that group A developed sympathetic ophthalmia,group B and grouP C could not develop sympathetic ophthalmia.As cyclosporine is a selective suppressive drug to T lymphoeyte the authors suppose that the pathogenesis of sympathetic ophthalmia is closely related to T lymphocyte.

以13只白色豚鼠作实验,其中3只为 C 组作对照,另10只分为 A、B 二个组,在以牛晶体蛋白连续皮内注射4次致敏之后,做一只眼的晶体截囊术。术后 A 组皮下注射生理盐水,B 组则皮下注射环孢霉素(Cyclosporine)。结果 A 组发生交感性眼炎,而 B 组和 C 组均未发生。因为环孢霉素具有选择性的抑制 T 淋巴细胞的功能,故推测交感性眼炎的发病机制可能与 T 淋巴细胞的关系极为密切。

Cyclosporine was extracted from whole blood and analyzed by HPLC. The pharmacokinetics of oral cyclosporine were studied in patients with renal transplant. They were 5 women and 3 men between the ages of 29~49 years. Cyclosporine was used for 47 days to 11 months after renal transplantation. The mean dose was 8.26±1.41 mg/kg. d (5.88~10.0 mg/kg.d), once each 12 hours. Three hundreds whble blood samples were monitored. The peak concentration (C_(max)) was 664.9±87.5 ng/ml; peak time was 3.27±1.07...

Cyclosporine was extracted from whole blood and analyzed by HPLC. The pharmacokinetics of oral cyclosporine were studied in patients with renal transplant. They were 5 women and 3 men between the ages of 29~49 years. Cyclosporine was used for 47 days to 11 months after renal transplantation. The mean dose was 8.26±1.41 mg/kg. d (5.88~10.0 mg/kg.d), once each 12 hours. Three hundreds whble blood samples were monitored. The peak concentration (C_(max)) was 664.9±87.5 ng/ml; peak time was 3.27±1.07 h; slow elimination phase t_(1/(2β)) was 13.53 (6. 13~43.3) h.

本文用HPLC法测定环孢素的全血浓度,对8例异体肾移植病人口服环孢素后的药代动力学特性进行研究。病人在肾移植后用环孢素的时间为47天到11个月,平均给药剂量为8.26±1.41 mg/kg·d(5.88~10.0mg/kg·d),每12h一次。病人常规监测血样本300余次。测得病人的环孢素药代动力学参数:峰浓度(Cmax)664.9±87.5 ng/ml,达峰时间(Tmax)3.27±1.07h;t~(2/2)β13.53h(6.13~44.3h)。

The cyclosporine concentration in whole blood of the renal transplantationpatients was determined by improved HPLC.The Ultrasphere CN analysis columnwater-methanol-acetonitrile mobile phase,column temperature 50℃ were used.The separation and column effect were better than that of routine methods.Thecolumn temperature was relatively low.The pharmacokinetics of oral cyclospo-rine were studied in 10 renal transplantation patients.Four hundreds whole bloodsample were monitored.The mean peak time was 3.12±0.96h,rapid...

The cyclosporine concentration in whole blood of the renal transplantationpatients was determined by improved HPLC.The Ultrasphere CN analysis columnwater-methanol-acetonitrile mobile phase,column temperature 50℃ were used.The separation and column effect were better than that of routine methods.Thecolumn temperature was relatively low.The pharmacokinetics of oral cyclospo-rine were studied in 10 renal transplantation patients.Four hundreds whole bloodsample were monitored.The mean peak time was 3.12±0.96h,rapid elimination(α)0.730±0.261/h,slow elimination t1/2β 13.18h in 10 patients.

用改进的HPLC法测定肾移植病人全血中环孢素浓度,我们采用Ultrasphere CN 柱水、甲醇、乙腈三元溶剂为流动相,50℃柱温分析,它较报道的常规方法分离好,柱效高,柱温低。用本法对10例肾移植病人口服环孢素的药代动力学特性进行研究,常规监测病人血药浓度百余次。10个病人的平均tpk3.12±0.96h,α0.730±0.261h~(-1),t_(1/2)β13.18h。

 
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