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healthy
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  名健康
    Pharmacokinetics of 3 different kinds of ciprofloxacin preparations in 62 healthy volunteers
    环丙沙星3种剂型在62名健康志愿者的药物动力学研究
短句来源
    Methods:Twenty male healthy volunteers received 2mg finasteride tablet orally in a random crossover design.
    方法采用随机双交叉实验设计,20名健康受试者口服受试制剂和参比制剂2mg,用LC-MS法测定国人血浆中的非那雄胺浓度。
短句来源
    METHODS: The study was conducted as a 3- way crossover design in 18 healthy volunteers whose plasma concentrations of cefixime were determined by HPLC after receiving a single oral dose of 200 mg trial preparations or reference preparation.
    方法:采用高效液相色谱法测定18名健康受试者三交叉单剂量口服受试制剂或参比制剂200mg后血浆中头孢克肟的浓度。
短句来源
    METHODS A single oral dose of 7.5 mg domestic and imported zolmitriptan tablets was given to 24 healthy volunteers in a randomized cross-over study.
    方法24名健康男性受试者随机交叉给药,分别单剂口服国产和进口佐米曲坦片7.5mg。
短句来源
    Methods Twenty healthy male volunteers received 200 mg nevirapine tablets orally in a random crossover design. Drug concentrations in the plasma were determined by HPLC.
    方法采用随机双交叉实验设计,20名健康受试者口服受试制剂和参比制剂200 mg,用HPLC法测定血浆中的奈韦拉平浓度。
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  “healthy”译为未确定词的双语例句
    Relation of P450 2C9 Genetic Polymorphisms to Pharmacokinetics of Sulfonylurea Hypoglycemic Agent in Chinese Healthy Volunteers
    中国人群P450 2C9基因多态性与磺脲类药物代谢的关系
短句来源
    Study on the bioavailability of naproxen sodium and its pharmacokinetics in healthy volunteers
    萘普生钠片剂和胶囊剂生物利用度及药物动力学研究
短句来源
    Detrmination of Acelylating Rate of Sulfamethazine on 200 Tibetan Healthy Volunteers
    200名藏族志愿者磺胺二甲嘧啶乙酰化代谢率分型测定
短句来源
    A Pharmacokinetic Study on Mannitol Administered Orally in Healthy Volunteers
    正常人口服甘露醇的药动学研究
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    Studies on Process of Healthy Drink of Asparagus SOD
    芦笋SOD口服液工艺的研究
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  healthy
Study subjects were divided into three groups: subjects in group 1 were microalbuminuric diabetic (n = 33), in group 2 subjects were normoalbuminuric diabetic group (n = 32), and group 3 was formed from nondiabetic healthy control subjects (n = 18).
      
As both P and Q are constant for a healthy motor, they are represented by a dot on the PQ plane.
      
In the dry year (2002), for several months, soil water content of potted trees was lower than its threshold value for non-available soil water content, which could influence the healthy growth of trees.
      
Genomic DNA was extracted from blood samples of healthy controls and from patients with HBV infection.
      
Eight young, healthy male volunteers were exposed to two 24 h periods of continuous wakefulness during the crossover experiment.
      
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The fasting gastric juices involving gastric residuum and basal sec- retion of 56 healthy medical students,including 22 women,had been determined. The basal secretion of empty stomachs was aspirated every 15 minutes and 4 sam- ples were taken from each donor.The results show very marked individual differ- ences.The values for gastric residuum are:total amount,0.2—95.0 ml;free HCl and total acidity,0—85.0 and 6.0—108.0 m.equ./1;peptic power,0—63 units.Those for basal secretion are:total amount,0.2—63.0...

The fasting gastric juices involving gastric residuum and basal sec- retion of 56 healthy medical students,including 22 women,had been determined. The basal secretion of empty stomachs was aspirated every 15 minutes and 4 sam- ples were taken from each donor.The results show very marked individual differ- ences.The values for gastric residuum are:total amount,0.2—95.0 ml;free HCl and total acidity,0—85.0 and 6.0—108.0 m.equ./1;peptic power,0—63 units.Those for basal secretion are:total amount,0.2—63.0 ml;free HCl and total acidity,0—107.0 and 7.0—131.0 m.equ./1;peptic power,0—80.0 units.Generally,the secretion for men are greater than those for women,and in both sexes the acidity and peptic power of basal secretion are higher than those of gastric residuum.

我们共检查了56例正常青年(男34人,女22人)的空腹胃液,包括残余胃液及基础胃淑,基础胃液每15分鐘抽一次,一连4次。其结果是:空腹胃液的个体差异很大,分泌类型也很复杂,男女合计,残余胃液的总量为2.0—95.0毫升,自由盐酸和总酸分别为0—85.0与6.0—108.0每升毫克分子量,蛋白酶消化力为0—63罩位。基础胃液每15分鐘的分泌量为0.2—63.0毫升,自由盐酸和总酸分别为0—107.0与7.0—131.0每升毫克分子量,蛋白酶清化力为0—80.0罩位。一般说来,男性的数值大于女性,基础胃液的酸度和酶消化力高于残余胃液。

Chrysanthemum indicum is effective in lowering blood pressure. Extraction with hot ethanol yielded an active fraction, HC-1. In anesthetized cats, intraduodenal injetions of 50—100 mg/kg of HC-1 produced an average "% of hypotensive areas" in 2 hours varying from -19% to -22%. Four normotensive dogs were fed 50, 100, 130 and 150 mg/kg resp., and the diastolic pressure dropped 0, 24, 8 and 36 mm Hg resp. The hypotensive action was slow and lasted more than 2 hours. Three renal hypertensive dogs were fed daily...

Chrysanthemum indicum is effective in lowering blood pressure. Extraction with hot ethanol yielded an active fraction, HC-1. In anesthetized cats, intraduodenal injetions of 50—100 mg/kg of HC-1 produced an average "% of hypotensive areas" in 2 hours varying from -19% to -22%. Four normotensive dogs were fed 50, 100, 130 and 150 mg/kg resp., and the diastolic pressure dropped 0, 24, 8 and 36 mm Hg resp. The hypotensive action was slow and lasted more than 2 hours. Three renal hypertensive dogs were fed daily 100 mg/kg in the first 2 weeks, and 200 mg/kg for the 3rd week. Weekly tests on EKG, serum BSP retention, and blood NPN revealed no serious alterations. In two of them the blood pressure was brought down significantly. Daily feeding of 300 mg/kg to one healthy dog for 3 weeks brought forth no grave reactions except vomiting at times. HC-1 is marked with (a) high yield, (b) low toxicity, (c) mild action, and (d) certain hypotensive effects in anesthetized and unanesthetized animals. So it may be recommended to clinical trial.

野菊花降压有效。本文实验用热醇提取出有效成分HC-1,并研究其疗效及毒性。麻醉猫小肠注射50—100毫克/公斤,2小时内的降压面积百分比为-19至-22%。正常血压狗4只,分别灌服50,100,130及150毫克/公斤,舒张压分别下降0,24,8及36毫米汞柱,作用缓慢,维持2小时以上。慢性肾型高血压狗3只,前2周每日灌胃100毫克/公斤,第3周每日灌胃200毫克/公斤。其中2狗血压显著降低。这3狗每周作心电图、血清磺溴酞钠存留率及全血非蛋白氮含量的测定,未见到严重毒性反应。另1只正常狗每日服300毫克/公斤,连续3周,除有时呕吐外,亦无其他严重毒性反应。 HC-1产量较高,毒性不大,作用缓和,对麻醉与不麻醉动物有一定降压效果,可以推荐临床试用。

Healthy adult male animals (48 guinea pigs and 8 rats), showing allert responses

1.本实验选用听觉灵敏、平衡良好、体重在220—300克健康雄性豚鼠48只作慢性实验(实验25只、对照23只),8只雄性大鼠作急性实验(对照、实验各半)。慢性实验者每日一次肌肉内注射链霉素(硫酸盐),剂量为400毫克/公斤加葡萄糖酸钙,200毫克/公斤,100毫克/公斤。急性组一次肌肉内注射600毫克/公斤链霉素。 2.100毫克/公斤剂量者,连续注射任达一个月机能试验和组织化学检查均未见明显变化。400毫克/公斤+Ca及200毫克/公斤剂量者,实验动物平均在2个月左右眼震丧失,听力迟钝。但也有个别动物短在22天,长达158天才出现中毒症状者。 3.本实验对动物的桥脑和延脑进行了组织化学观察,结果表明,慢性中毒豚鼠耳蜗神经腹侧终核、前庭神经外侧终核、三叉神经起核内嫌色性细胞(即本实验中的Ⅲ型细胞)增多。SH基、蛋白质结合的组氨酸、酪氨酸、色氨酸、PAS反应、琥珀酸脱氢酶反应普遍减弱。碱性和酸性磷酸酶活性未见明显变化。 4.对急性和部分慢性中毒动物肋间肌运动终板乙酰胆碱酯酶进行了组织化学检查。急性中毒动物乙酰胆碱酯酶活性减弱,慢性中毒动物者未见明显变化。 5.实验证明:葡萄糖酸钙有解除动物的急性中毒和提高对链霉...

1.本实验选用听觉灵敏、平衡良好、体重在220—300克健康雄性豚鼠48只作慢性实验(实验25只、对照23只),8只雄性大鼠作急性实验(对照、实验各半)。慢性实验者每日一次肌肉内注射链霉素(硫酸盐),剂量为400毫克/公斤加葡萄糖酸钙,200毫克/公斤,100毫克/公斤。急性组一次肌肉内注射600毫克/公斤链霉素。 2.100毫克/公斤剂量者,连续注射任达一个月机能试验和组织化学检查均未见明显变化。400毫克/公斤+Ca及200毫克/公斤剂量者,实验动物平均在2个月左右眼震丧失,听力迟钝。但也有个别动物短在22天,长达158天才出现中毒症状者。 3.本实验对动物的桥脑和延脑进行了组织化学观察,结果表明,慢性中毒豚鼠耳蜗神经腹侧终核、前庭神经外侧终核、三叉神经起核内嫌色性细胞(即本实验中的Ⅲ型细胞)增多。SH基、蛋白质结合的组氨酸、酪氨酸、色氨酸、PAS反应、琥珀酸脱氢酶反应普遍减弱。碱性和酸性磷酸酶活性未见明显变化。 4.对急性和部分慢性中毒动物肋间肌运动终板乙酰胆碱酯酶进行了组织化学检查。急性中毒动物乙酰胆碱酯酶活性减弱,慢性中毒动物者未见明显变化。 5.实验证明:葡萄糖酸钙有解除动物的急性中毒和提高对链霉素耐受剂量的作用。 6.作者认为链霉素对中枢神经系的毒性作用是普遍的。本文对于一些结果进行了讨论。

 
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