[Methods] immunohistochemical SP method was used to detect the expression of HPV16-E6 and it′s positive rate in 23 cervical infiltrating carcinoma patients, 25 chronic inflammation patients and 26 normal control.
Results Positive rate of HTERT in NPC was 83 7%(70/84),while positive rate of HTERT in dysplasia of nasopharyngeal epithelium and chronic inflammation of nasopharyngeal epithelium both were 0 0%(0/8 and 0/16) (P<0 01),there are significant differences for HTERT in positive rate of clinical TNM stage group and for HTERT in positive intensity of lymph node metastasis group (P<0 05).
Results: The positive signal of HPV was mainly located in the nuclei of the cells. 48.81% (41/84)of squamous cell carcinoma(SQCC) and 6.12%(6/49) of chronic inflammation tissue were positive for HPV-DNA by in situ hybridization;
Methods Immunohistochemical method was used to determine the expression of P63 and PTEN protein in 68 cases of NPC,25 cases of nearby mucosa of the carcinoma and 20 cases of chronic inflammation of nasopharyngeal mucosa. The relationship between the gene expression and clinicopathological features,metastasis was analyzed.
Conclusion:The production of the recombinant adenovirus vector encoding NF κB RNA aptamer provides a foundation for investigation of its activity and gene therapy for treatment of acute and chronic inflammation caused by NF κB over activity in clinic.
Results The positive rates of HPV16/18DNA and COX-2 protein in cervical adenocarcinoma were 65.1% and 86.0% respectively,which significantly higher than that in cervical chronic inflammation 8.3% and 33.3% (P< 0.01 ).
[Results] The positive rates of HPV16/18DNA and Skp2 protein in cervical adenocarcinoma were 65.1% and 68.6% respectively, which significantly higher than that in cervical chronic inflammation(P <0.01).
In addition to having a key role in thrombogenesis, platelets are actively involved in acute and chronic inflammation: they induce the release of proinflammatory mediators, expose adhesion molecules, and recruit leukocytes.
Protease-antiprotease imbalance, generation of oxidative stress, and chronic inflammation are recognized as the principal mechanisms leading to irreversible airflow obstruction and parenchymal destruction in the lung.
Further characterizations of DN Treg cells are that infection indicates that MHV-3 could induce the chronic inflammation in livers of C3H/Hej mice.
When the endothelium is physically disrupted or functionally perturbed by postischemic reperfusion, acute and chronic inflammation, atherosclerosis, diabetes and chronic arterial hypertension, then completely opposing actions pertain.
Chronic inflammation or myocarditis and chronic alcohol abuse are considered two main etiologic factors in dilated cardiomyopathy.