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   plasma fibrinogen 的翻译结果: 查询用时:0.211秒
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plasma fibrinogen
相关语句
  血浆纤维蛋白原
     Objective To investigate the allelic frequencies of polymorphisms of αTaqⅠ and βBclⅠ, HinfⅠA/C,448 G/A,βBsmAⅠG/C,+1689T/G,-148C/T,-249C/T,-455G/A in Hainan Han population and their association with plasma fibrinogen level.
     目的调查海南汉族健康人群αTaqⅠ和βBclⅠ、HinfⅠA/C、448G/A、βBsmAⅠG/C、+1689T/G、-148C/T、-249C/T、-455G/A多态性的等位基因频率及其与血浆纤维蛋白原(fibrinogen,Fg)水平的关系。
短句来源
     (2) Comparison of plasma fibrinogen: It was lower significantly in the treatment group after treatment for 21 days and 7 days than before treatment [(462.50 ±37.6,497.62 ±39.2,558.30 ±1.40)g/L,t =5.42-17.22,P < 0.01].
     ②血浆纤维蛋白原比较:治疗组治疗21 d,7 d后明显比治疗前低[(462.50+37.6,497.62±39.2,558.30±1.40)g/L,t=5.42-17.22, P<0.01];
短句来源
     The study of beta fibrinogen gene-455 G/A、-148 C/T、448 G/A polymorphisms and their association with plasma fibrinogen levels
     纤维蛋白原β-455G/A、-148C/T、448G/A基因多态性与血浆纤维蛋白原水平的关系
短句来源
     The Plasma fibrinogen levels in the samples of genotype B1B2 and B2B2 was higher than that in samples of B1B1(P<( 0.05).)
     B1B2、B2B2基因型血浆纤维蛋白原水平明显高于B1B1基因型(P<0.05)。
短句来源
     Using stepwise multiple regression analyses,plasma fibrinogen(beta coefficient-0.407,p<0.001),tHcy(beta coefficient-0.471,p=0.001),and urate(beta coefficient 0.279,p=0.031)were found to be independent predictors of the ABR in patients(ABR=1-0.669×fibrinogen-0.450×tHcy+0.449×urate,p<0.001).
     通过逐步多元回归分析,如下因素为ABR的独立判定指标,血浆纤维蛋白原(β系数-0.47,p<0.001),tHcy(p系数-0.471,p=0.001)及尿酸盐(β系数0.279,p=0.031),公式如下:(ABR=1-0.669×血浆纤维蛋白原-0.450×tHcy+0.449×尿酸盐,p<0.001)。
短句来源
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  纤维蛋白原
     Objective To investigate the allelic frequencies of polymorphisms of αTaqⅠ and βBclⅠ, HinfⅠA/C,448 G/A,βBsmAⅠG/C,+1689T/G,-148C/T,-249C/T,-455G/A in Hainan Han population and their association with plasma fibrinogen level.
     目的调查海南汉族健康人群αTaqⅠ和βBclⅠ、HinfⅠA/C、448G/A、βBsmAⅠG/C、+1689T/G、-148C/T、-249C/T、-455G/A多态性的等位基因频率及其与血浆纤维蛋白原(fibrinogen,Fg)水平的关系。
短句来源
     (2) Comparison of plasma fibrinogen: It was lower significantly in the treatment group after treatment for 21 days and 7 days than before treatment [(462.50 ±37.6,497.62 ±39.2,558.30 ±1.40)g/L,t =5.42-17.22,P < 0.01].
     ②血浆纤维蛋白原比较:治疗组治疗21 d,7 d后明显比治疗前低[(462.50+37.6,497.62±39.2,558.30±1.40)g/L,t=5.42-17.22, P<0.01];
短句来源
     Plasma fibrinogen (r=0.776,P=0.01),plasma viscosity(r=0.702,P=0.01)and hsCRP(r=0.256,P=0.01) was correlated with apnea hyponea index (AHI).
     纤维蛋白原(r=0.776,P=0.01)、血浆黏度(r=0.702,P=0.01)、hsCRP(r=0.256,P=0.01)与呼吸紊乱指数(AHI)之间有相关性。
短句来源
     The study of beta fibrinogen gene-455 G/A、-148 C/T、448 G/A polymorphisms and their association with plasma fibrinogen levels
     纤维蛋白原β-455G/A、-148C/T、448G/A基因多态性与血浆纤维蛋白原水平的关系
短句来源
     The Plasma fibrinogen levels in the samples of genotype B1B2 and B2B2 was higher than that in samples of B1B1(P<( 0.05).)
     B1B2、B2B2基因型血浆纤维蛋白原水平明显高于B1B1基因型(P<0.05)。
短句来源
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  血浆fg
     In the men, plasma fibrinogen level is significantly higher in the groups of genotypes -455GA and AA, -148CT and TT, αTaqⅠ T1T1, αTaqⅠ T1T2 than in the group of wild types(P=0.001,0.023,0.003 and 0.032 respectively).
     在男性人群中,-455GA和AA基因型、-148CT和TT基因型、αTaqⅠT1T1、αTaqⅠT1T2基因型组的血浆Fg水平比野生型组高(P值均<0.01)。
短句来源
     The plasma fibrinogen levels showed no significant difference between the two groups(2.70±(1.05 g/L) vs 2.62±0.51g/L,P>0.05).
     CI组血浆Fg水平(2.70±1.05 g/L)和对照组(2.62±0.51 g/L)比较差异无显著性意义(P>0.05)。
短句来源
     In the general population, the plasma fibrinogen level is significantly higher in the groups of genotypes -455GA and AA, -148CT and TT, αTaqⅠ T1T1 than in the group of wild types(P=0.004, 0.015 and 0.043 respectively).
     在总人群中,-455GA和AA基因型、-148CT和TT基因型、αTaqⅠT1T1基因型组的血浆Fg水平比野生型组高(P值均<0.01);
短句来源
     The β-455G/A β448G/A,α-Fg TaqⅠ polymorphisms were associated with the difference in plasma fibrinogen in men. A -455, T -148 and α TaqⅠ T1 alleles were associated with higher fibrinogen levels.
     A-455、T-148、αTaqⅠT1位点与血浆Fg水平增高关联,βFg455G/A、-148C/T及αTaqⅠ多态性与男性血浆Fg水平关联。
短句来源
     Results In CHD cases and controls,the level of plasma fibrinogen was(4 3±1 1)and(3 6±1 3)g/L( P <0 01),respectively.
     结果 CHD患者和正常人的血浆 Fg水平分别为 (4.3± 1 .1 )和 (3.6± 1 .3) g/ L,CHD患者的血浆 Fg浓度明显高于正常人 (P<0 .0 1 )。
短句来源
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  “plasma fibrinogen”译为未确定词的双语例句
     The plasma fibrinogen levels in the groups of ischemic stroke (3.23±1.09 g/L) and cerebral hemorrhage (3.36±0.58 g/L) were also significantly higher than that in the control group (2.85±0.76 g/L).
     且-148CT/TT的脑梗死组、脑出血组的Fg水平分别为(3.23±1.09)g/L、(3.36±0.58)g/L,也明显高于对照组(2.85±0.76)g/L。
短句来源
     Results: (1) The levels of plasma fibrinogen were higher in 350 patients with CHD than that in 260 patients without CHD[ (3.86 + 0.87)g/L and (2.76 + 0.72)g/L respectively, P<0.01) ].
     结果:(1)350例CHD患者FIB水平明显高于260例冠状动脉正常者[(3.86±0.87)g/Lvs(2.76±0.72)g/L,P<0.01];
短句来源
     and the plasma fibrinogen levels of those with -148T allele were higher than that of those without -148T allele, 3.29 + 0.66 versus 2.33 + 0.77 (P<0.01) and 3.77 + 0.65 versus 3.31 + 0.97 (P<0.01) respectively.
     对照组和CI组中-148T携带者的Fg水平亦均高于非携带者,分别为3.29±0.66和2.33±0.77g/l(P<0.01)、3.77±0.65和3.31±0.97g/l(P<0.01)。
短句来源
     (4)In both control group and CI group, the plasma fibrinogen levels of those with -455A allele were higher than that of those without -455A allele,3.44+0.67 versus 2.32+0.77 (P<0.01) and 3.80 + 0.64 versus 3.31 + 0.97 (p<0.05) respectively;
     (4)对照组和CI组中-455A等位基因携带者的Fg水平均高于非携带者,分别为3.44±0.67和2.32±0.77g/l(P<0.01)、3.80±0.64和3.31±0.97g/l(P<0.05);
短句来源
     In both control group and CI group,the plasma fibrinogen levels with-455A allele were higher than that of without-455A allele,3.44±0.67 versus 2.32±0.77(P<0.01)and 3.80± 0.64 versus 3.31±0.97(P<0.05) respectively;
     对照组和 CI组中 - 4 5 5 A等位基因携带者的 Fg水平均高于非携带者 ,分别为 3.4 4± 0 .6 7和2 .32± 0 .77(P<0 .0 1)、3.80± 0 .6 4和 3.31± 0 .97(P<0 .0 5 ) ;
短句来源
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  plasma fibrinogen
The adsorption of bovine plasma fibrinogen (BPF) onto the PU/PS IPNs and PU homopolymers was effectively suppressed by the PEO-grafting.
      
As a result, the amount of the adsorbed bovine plasma fibrinogen and bovine serum γ-globulin on the block copolymer surface was reduced dramatically.
      
For example, marked increase in blood viscosity linked with elevated fibrinogen level appeared in slight liver damage, whereas reduced blood viscosity associated with decreased plasma fibrinogen level and hematocrit occured in severe liver damage.
      
This method could also be used to measure the plasma fibrinogen concentration at the same time.
      
Serum zinc correlated negatively with plasma fibrinogen (r=-0.69,p>amp;lt;0.005) and serum copper correlated positively with serum ceruloplasmin (r=0.92,p>amp;lt;0.0005) both in indomethacin-treated and untreated arthritic rats.
      
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(1)The present communication is a continuation of previous study of drugs on the pathologico-physiological reactions of the infected rabbits.The following indices of the reactions were used,namely:(1) erythrocyte sedimentation rate (ESR),(2) plasma fibrinogen content,(3) plasma gamma globulin content,(4) prothrombin time and (5)body weight. (2)It was shown that a full course of potassium antimony tartrate (PAT) could depress the abnormal rise of ESR of the infected rabbit.The effect was more striking...

(1)The present communication is a continuation of previous study of drugs on the pathologico-physiological reactions of the infected rabbits.The following indices of the reactions were used,namely:(1) erythrocyte sedimentation rate (ESR),(2) plasma fibrinogen content,(3) plasma gamma globulin content,(4) prothrombin time and (5)body weight. (2)It was shown that a full course of potassium antimony tartrate (PAT) could depress the abnormal rise of ESR of the infected rabbit.The effect was more striking in the early (i.e.7th day after inoculation) than the late treatment (i.e.33rd day after inoculation).This effect of PAT on the ESR was found to be in parallelism with its therapeutic effect.This method may be utilized for evaluation of drugs against schistosomiasis. (3)Neither PAT nor strychnine had any effect on the ESR of the normal rabbit.Strychnine was also found to have no significant effect on the ESR of the infected rabbit,but it could markedly modify the inhibitory effect of the PAT. (4)The therapeutic effect of half-course of PAT was found to be about 10—20% less marked than that of combined treatment with strychnine. Strychnine alone did not show any therapeutic effect.It was also found that the dose of strychnine used in our experiment did not increase the toxicity of PAT as shown by mice toxicity test. (5)The therapeutic dose of PAT showed no effect on the plasma fibrinogen content of the normal rabbit but it could bring the increased plasma fibrinogen content back to normal in the infected animal. (6)After a course of PAT in the infected animal,the double peak rise of the palsma gamma globulin content was distinctly suppressed as compared with the control group.On the contrary,the new drug,1:7-Bis (p-dimethylaminophenoxy) heptane (APH) did not show the same effect, probably indicating its weak action against schistosomiasis. (7)The body weight of the PAT treated group was found to be much higher than the non-treated group,However,the group treated with APH showed a continuous drop of body weight. (8)It has been found,as by others,that the APH showed high toxicity and low therapeutic effect in the experimental animals.From the fact that APH showed pronounced effect on ESR and plasma fibrinogen content of the infected animal,one could not yet decide,with the available data,whether these effects are due to its action on the schistosome or its eggs,or to its toxic action on the host.

(一)本文报告了药物对于血吸虫病病兔及正常家兔的红血球沉降率,血浆纤维蛋白,丙种球蛋白,凝血酶元时值及体重的影响。(二)酒石酸锑钾的治疗,无论在家兔患病的早期或后期,均可抑制其血沉的加速,而以早期治疗的抑制作用更为显著。同时这个抑制血沉的作用与治疗后的成虫发育率是符合的。因此利用这种方法,可以考虑作为研究一些治疗血吸虫病药物的疗效指标。(三)酒石酸锑钾及士的宁本身对正常家兔的血沉并不引起改变,士的宁对于病兔的血沉也无明显作用,但士的宁可以影响酒石酸锑钾对病兔血沉的抑制作用。 (四)半疗程剂量酒石酸锑钾并用士的宁之疗效较单独应用半疗程剂量酒石酸锑钾者为高(10—20%),而单独应用士的宁并无任何疗效,轻度激动量士的宁也不增加酒石酸锑钾的毒性。(五)酒石酸锑钾的治疗剂量对于正常家兔之血浆纤维蛋白元无明显影响,但能使病兔增高之血浆纤维蛋白元回复正常。(六)酒石酸锑钾的治疗可以使病兔的丙种球蛋白在一定时期内保持在接近正常值范围内,这一抑制作用与感染对照组相比,甚为明显,而氨苯氧烷却无此作用,这一点可能与疗效是有关系的。(七)酒石酸锑钾治疗后的病兔之体重较感染对照组病兔显著增高,而经氨苯氧烷治疗后之病兔,其体重仍日见减...

(一)本文报告了药物对于血吸虫病病兔及正常家兔的红血球沉降率,血浆纤维蛋白,丙种球蛋白,凝血酶元时值及体重的影响。(二)酒石酸锑钾的治疗,无论在家兔患病的早期或后期,均可抑制其血沉的加速,而以早期治疗的抑制作用更为显著。同时这个抑制血沉的作用与治疗后的成虫发育率是符合的。因此利用这种方法,可以考虑作为研究一些治疗血吸虫病药物的疗效指标。(三)酒石酸锑钾及士的宁本身对正常家兔的血沉并不引起改变,士的宁对于病兔的血沉也无明显作用,但士的宁可以影响酒石酸锑钾对病兔血沉的抑制作用。 (四)半疗程剂量酒石酸锑钾并用士的宁之疗效较单独应用半疗程剂量酒石酸锑钾者为高(10—20%),而单独应用士的宁并无任何疗效,轻度激动量士的宁也不增加酒石酸锑钾的毒性。(五)酒石酸锑钾的治疗剂量对于正常家兔之血浆纤维蛋白元无明显影响,但能使病兔增高之血浆纤维蛋白元回复正常。(六)酒石酸锑钾的治疗可以使病兔的丙种球蛋白在一定时期内保持在接近正常值范围内,这一抑制作用与感染对照组相比,甚为明显,而氨苯氧烷却无此作用,这一点可能与疗效是有关系的。(七)酒石酸锑钾治疗后的病兔之体重较感染对照组病兔显著增高,而经氨苯氧烷治疗后之病兔,其体重仍日见减轻。(八)氨苯氧烷有较高的毒性,但疗效甚低,它对病兔的血沉及纤维蛋白元所出现的抑制作用,究竟属于对血吸虫或其虫卵的作用,抑系对于病兔机体的毒性作用,目前还不能肯定。

In a previous study of pathologico-physiological reactions of the rabbits inoculated with cercariae of Schistosoma japonicum in this laboratory, it was found that reactions such as increase of erythrocyte sedimentation rate; plasma fibrinogen content, serum gamma globulin content, etc., occurred usually 4-5 weeks after exposure to the infestation. Investigations have now been made of: (1) the determination of the date of beginning of deposition of eggs in liver of the infected rabbits, (2) the correlation...

In a previous study of pathologico-physiological reactions of the rabbits inoculated with cercariae of Schistosoma japonicum in this laboratory, it was found that reactions such as increase of erythrocyte sedimentation rate; plasma fibrinogen content, serum gamma globulin content, etc., occurred usually 4-5 weeks after exposure to the infestation. Investigations have now been made of: (1) the determination of the date of beginning of deposition of eggs in liver of the infected rabbits, (2) the correlation between the number of eggs recovered from the whole liver tissue and the severity of the reactions of the infected animal, and (3) the reactions induced by the injection of living and heat-killed schistosome eggs to the portal circulation of the normal rabbits. The earliest date of deposition of eggs of S. japonicum in liver of infected rabbits was found to be the 23rd day after exposure to the cercariae. The eggs were isolated from the liver tissue digested by 10% KOH, then examined and counted under the microscope. However, the pathologico-physiological reactions of the infected animal did not occur until the 32nd day after infestation. The severity of these reactions as observed in the subsequent weeks was found to be exactly parallel to the number of eggs deposited in the liver. It was also shown that the number of eggs recovered from the liver estimated in terms of each female worm per day was approximately 764-1097 eggs. A direct proof that eggs of S. japonicum could indeed induce the reactions of the normal rabbits was made. It was established that only living eggs given to the portal circulation were effective whereas heat-killed eggs did not give any significant effect. In the same experiment, sera of the healthy rabbits taken at the 10th day after a single transfusion of living eggs showed a positive complement fixation test by using egg-polysaccharides as antigen. The latter was discovered and isolated by Lin Hui in this laboratory. In comparison, sera of the infected animal (600 cercariae) taken 35th day after inoculation showed positive complement fixation reaction when either the eggpolysaccharides or the egg extract was used as antigen. From the above findings, we concluded that eggs of S. japonicum are indeed the cause of the pathologico-physiological reactions of the infected animal as judged by our indices. We are also inclined to believe that the severity of reactions of the infected animal depends on the quantity of eggs deposited in the liver but the possibility of toxic substances secreted by eggs during its developing stage can not be excluded.

(一)本文報告了二個實驗:(1)家兔感染日本血吸蟲尾蚴後,定期觀察其機體反應性改变的指標,並自感染後第21天起,分批解剖病兔,以10%氫氧化鉀溶液消化其肝臟法確定蟲卵進入病兔肝臟的日期及肝臟內蟲卵量與病兔機體反應變化的關係。(2)向健康家兔門靜脈內注射大量日本血吸蟲活蟲卵及死蟲卵後,觀察蟲卵對其機體反應的影響。本文實驗證明了血吸蟲蟲卵確能引起家兔機體反應的变化,並肯定了蟲卵為日本血吸蟲病病因学中的主要因素。 (二)家兔經日本血吸蟲尾蚴感染後第23天,其肝臟內開始沉積蟲卵,至感染後第32天,病兔之機體反應開始出現明顯變化,這些變化與其肝臟內血吸蟲蟲卵量有着一定關係,我們認為病兔機體反應的變化是由於病兔肝內的蟲卵在成熟過程中所分泌的化學物質的刺激而發生的。 (三)向健康家兔門靜脈內注射大量日本血吸蟲的活蟲卵後,可以引起与尾蚴感染32天後病兔相似的病理生理反應性的改變,而注射死蟲卵及生理鹽水對照者的此種反應就不明顯。 (四)家兔體內每個日本血吸蟲雌蟲每天所產的卵在家兔肝臟内可發現的數目為764—1097個。 (五)根據感染600條尾蚴的日本血吸蟲病兔血清与蟲卵抗原的補體結合試驗的結果,發現病兔在感染後第25天時,其...

(一)本文報告了二個實驗:(1)家兔感染日本血吸蟲尾蚴後,定期觀察其機體反應性改变的指標,並自感染後第21天起,分批解剖病兔,以10%氫氧化鉀溶液消化其肝臟法確定蟲卵進入病兔肝臟的日期及肝臟內蟲卵量與病兔機體反應變化的關係。(2)向健康家兔門靜脈內注射大量日本血吸蟲活蟲卵及死蟲卵後,觀察蟲卵對其機體反應的影響。本文實驗證明了血吸蟲蟲卵確能引起家兔機體反應的变化,並肯定了蟲卵為日本血吸蟲病病因学中的主要因素。 (二)家兔經日本血吸蟲尾蚴感染後第23天,其肝臟內開始沉積蟲卵,至感染後第32天,病兔之機體反應開始出現明顯變化,這些變化與其肝臟內血吸蟲蟲卵量有着一定關係,我們認為病兔機體反應的變化是由於病兔肝內的蟲卵在成熟過程中所分泌的化學物質的刺激而發生的。 (三)向健康家兔門靜脈內注射大量日本血吸蟲的活蟲卵後,可以引起与尾蚴感染32天後病兔相似的病理生理反應性的改變,而注射死蟲卵及生理鹽水對照者的此種反應就不明顯。 (四)家兔體內每個日本血吸蟲雌蟲每天所產的卵在家兔肝臟内可發現的數目為764—1097個。 (五)根據感染600條尾蚴的日本血吸蟲病兔血清与蟲卵抗原的補體結合試驗的結果,發現病兔在感染後第25天時,其血清對碎蟲卵浸液開始出現陽性,至感染後第35天,則全部呈陽性反應;而對蟲卵多醣則在感染後第35天才出現陽性,至感染後第49天,全部呈陽性反應。向健康家兔門靜脈內注射血吸蟲活蟲卵第10天後,其血清對蟲卵多醣出現陽性反應。

Based on the fact that during coagulation and fibrinolysis plasma changes from a liquid state to a gel and again from gel to a liquid state with a marked alteration in optical density, a method designated as 'Fibrino-lysodynamicogram' has been developed with which the whole process of coagulation and fibrinolysis can be recorded automatically as a continuous curve by a spectrophotometer.From this fibrinolysodynamicogram three parameters can be determined simultaneously, namely: plasma coagulation time, fibrinolysis...

Based on the fact that during coagulation and fibrinolysis plasma changes from a liquid state to a gel and again from gel to a liquid state with a marked alteration in optical density, a method designated as 'Fibrino-lysodynamicogram' has been developed with which the whole process of coagulation and fibrinolysis can be recorded automatically as a continuous curve by a spectrophotometer.From this fibrinolysodynamicogram three parameters can be determined simultaneously, namely: plasma coagulation time, fibrinolysis time and plasma clottability. Besides,the plasma fibrinogen content can be estimated.This method is simple, fast, sensitive in reaction and is capable of giving results with good reproducibility. It was used for observing fibrinolytic activities in chronic hepatitis,uraemia and acute myocardial infarction(M.I.), and measurig the changes of fibrinolytic activities produced during the process of treatming patients of M.I. with Chinese Traditional Medicine.This method and equipment may be used in any process which has an optical change during the course of reaction.

作者根据血浆在凝固和溶解过程中由液态→胶体→液态时在光密度上产生显著变化的特性,用分光光度计和电子电位差计自动描绘此变化的过程,得到一曲线图,——纤维蛋白溶解活性动态图。该图可同时反应血浆凝固时间、程度及凝块溶解时间等三个参数,并能计算出纤维蛋白的含量。用它观察慢性肝炎、尿毒症和急性心肌梗塞等疾病以及急性心肌梗塞患者治疗过程中纤溶系统活性的变化,结果比较满意.作者认为本方法操作简便、重复性好、反应灵敏、节省时间,凡在反应过程中光密度产生变化者均可应用,有推广价值。

 
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