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virus
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  病毒
    Study on the expression and genetic immunization of chimeric competent fragments of Hantaan virus M and S segments
    汉滩病毒M基因G2片段与S基因0.7Kb片段嵌合基因的表达及基因免疫的研究
短句来源
    Sequencing and analysis of complete genome of 84FLi strain-a Hantaan virus,isolated in Xi'an and Construction of Gl and G2 glycoprotein baculovirus expressi
    汉滩病毒西安分离毒株84FLi的全基因序列测定与分析及G1和G2糖蛋白杆状病毒表达载体的构建
短句来源
    Expression and Immunoactivity of HBsAg (hepatitis B Virus Surface Antigen) and HEV-NE2 (hepatitis E Virus ORF2 Gene) in Transgenic Tomato
    乙肝病毒表面抗原(HBsAg)、戊肝病毒ORF2基因片段NE_2在番茄中的表达及免疫活性
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    Complete Genomic Cloning and Development in the Reverse Genetics System for Infectious Bursal Disease Virus
    传染性法氏囊病病毒全基因组克隆及反向遗传系统的建立
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    Study of a Novel Genetic Vaccine Based on Alpha Virus Vector
    基于α-病毒载体的新型肿瘤基因疫苗的研究
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  肝炎病毒
    Studies on Establishment and Characteristics of Hepatitis G Virus Transgenic Mouse Models
    庚型肝炎病毒转基因小鼠模型的建立及其特性研究
短句来源
    Study on the Relationship between Hepatitis B Virus and Hepatocyte Apoptosis
    乙型肝炎病毒感染与肝细胞凋亡的关系研究
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    Studies on Relationship between Pathogenicity and Intracellular Signaling Initiated by Hepatitis C Virus E2 Protein
    丙型肝炎病毒E2蛋白引发细胞跨膜信号转导异常与致病性研究
短句来源
    Expression, Purification, and Applications of Hepatitis C Virus (HCV) Envelope Proteins
    丙型肝炎病毒被膜蛋白的表达、纯化与应用研究
短句来源
    Study on the Immunity of Recombinant Multiple Epitopes Antigen of Hepatitis C Virus
    丙型肝炎病毒重组复合表位抗原的免疫原性研究
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  型病毒
    Study on the Relation of Dengue 2 Virus' Receptor to Mesenteron Infection Barrier in Aedes Albopictus and Culex Pipiens Quinquefasciatus
    白纹伊蚊和致倦库蚊对登革2型病毒中肠感染屏障与病毒受体关系的研究
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    Study of C,PrM(M),Eand NS1 gene changes of two dengue-2 virus strains isolated in China
    我国两株登革2型病毒分离株结构蛋白C,PrM(M),E和非结构蛋白NS1基因变化的研究
短句来源
    NONSTRUCTURAL PROTEIN NS1 GENE OF A DENGUE-2 VIRUS 43 STRAIN ISOLATED IN CHINA
    我国登革2型病毒43株非结构蛋白NS1基因的特征
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    Effects of Herpes Simplex Virus Type Ⅱ Infection on Morphology and the Release of Lactate Dehydrogenase in Porcine Aortic Smooth Muscle Cells in Culture
    单纯疱疹Ⅱ型病毒感染对培养的猪主动脉平滑肌细胞形态和LDH释放的影响
短句来源
    Cloning and expression of the E gene of dengue- 2 virus strain in China
    我国登革2型病毒E基因的克隆与表达研究
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  “virus”译为未确定词的双语例句
    The Role of PACS-1 in trans-Golgi Network Localization of Herpes Simplex Virus 1 Glycoprotein B
    PACS-1在单纯疱疹病毒I型糖蛋白B定位于分泌高尔基体网络中的作用
短句来源
    Effects of Epstein-Barr Virus Protein on the Production of Immunoglubulin by Cultured B Lymphocytes as well as Cloning and Expressing of It's gp350~derived
    EB病毒蛋白对培养B细胞产生免疫球蛋白的影响及gp350相关肽段的克隆和表达
短句来源
    The Establishment of Transgenic Mouse Model Susceptible to Epstein-Barr Virus
    EBV易感转基因小鼠动物模型的建立
短句来源
    A Trial Study on Transforming Hepatitis B Virus as the Liver-targeting Gene Therapeutic Vector
    改造HBV作为肝靶向性基因治疗载体的研究
短句来源
    The Construction of DNA Vaccine of Herpes Simplex Virus Type Ⅱ Glycoprotein D with Chemokine MIP-1α and Preliminary Immunity in Mice
    单纯疱疹病毒Ⅱ型gD糖蛋白加趋化因子MIP-1α核酸疫苗的构建及初步免疫观察
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  virus
Human immunodeficiency virus type 1 (HIV-1) integrase is a potential target for anti-HIV therapy.
      
It is an essential enzyme required for replication of the acquired immunodeficiency syndrome (AIDS) virus.
      
Efavirenz is a trifluoromethylated inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) that shows good results in anti-HIV chemotherapy.
      
Derivatives on Herpes simplex virus type 1 (HSV-1), Mayaro virus (MAY) and vesicular stomatitis virus (VSV) were investigated.
      
Compounds 2d, 3f, 3a, and 3c exhibited antiviral activity against HSV-1, MAY, and VSV virus with EC50 values of 6.8, 2.2, 4.8, 0.52, 2.5, and 1.0.
      
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In this article,the authors give a report on the isolation of 9 strains of trachoma agent from 41 human cases,employing chick embrys techni- que.One of the 9 strains was further confirmed by inoculation into eyes of a monkey and of 2 human volunteers.In the latter,the inoculum of trachoma agent from third egg passage on conjunctiva induced typical acute manifestations and panus formation.From the artificially infected models,inclusion bodies were recovered on several occasions. The pertinent point for isolation...

In this article,the authors give a report on the isolation of 9 strains of trachoma agent from 41 human cases,employing chick embrys techni- que.One of the 9 strains was further confirmed by inoculation into eyes of a monkey and of 2 human volunteers.In the latter,the inoculum of trachoma agent from third egg passage on conjunctiva induced typical acute manifestations and panus formation.From the artificially infected models,inclusion bodies were recovered on several occasions. The pertinent point for isolation of trachoma agent lies in the successful control of bacterial contamination.In our experiences,incorporation of increased dose of streptomycin,addition of neomycin if necessary,and breaking up of ino- culum with sterile glass beads seemed to work satisfactorily.It is pointed out that chick embryos succumbing within 48 hours following inoculation,should not be regarded as due to non-specific cause,unless contamination has occurred.In order to increaee the positive rate of isolation of virus,the specimens should preferably come from children under 10 years of age,during Ⅰ_(++) or Ⅱ_(++) stages of infection. Besides fulfilling the requirements put forth by the International Committee on Trachoma, the data presented here is also deemed sufficient to meet the criteria for identification of “Viru- ses forming elementary bodies”,as demanded by Collier (1960).

本文报告1960-61这两年内,在上海地区从沙眼病人标本中共分离到了九株沙眼病毒。其中的一株,经过二位志愿者及猴眼的实验感染,均发生了与自然感染类似的临床症状,并从这些复制的模型中,多次找到了包涵体。文中详细介绍了分离病毒时应该注意的关键性问题和经验,并探讨了鉴定病毒的一些指标。同时提出我们工作中存在的问题和解决这些问题的方法。

Three virus-resistant L cell mutants were selected with mutagen-selec-tion method. These mutant cell lines were found to show marked changes in interferon induction and action systems. An accelerated interferon induction response was observed in mutant cell cultures when they were exposed to NDV. Induced mutant cells synthesized interferon mRNA more quickly, and the interferon titers after induction with poly 1 : C were higher in mutant cell lines than in the parent cell line. One virus-resistant...

Three virus-resistant L cell mutants were selected with mutagen-selec-tion method. These mutant cell lines were found to show marked changes in interferon induction and action systems. An accelerated interferon induction response was observed in mutant cell cultures when they were exposed to NDV. Induced mutant cells synthesized interferon mRNA more quickly, and the interferon titers after induction with poly 1 : C were higher in mutant cell lines than in the parent cell line. One virus-resistant L cell mutant was found to be more sensitive to the anti-cell-division activity caused by intracellular pppA2'P5'A2'P5'A.Results suggested that changes in interferon gene expression might account for the antiviral activity of these cell mutants.

用亚硝基胍诱变、VSV攻击选育的方法获得 3株抗病毒 L细胞系,后者对VSV、Sindbis病毒、痘菌病毒有明显的抗病毒性质。抗病毒细胞系的干扰素诱生系统和活性发挥系统都发生了明显的改变,表现在对病毒攻击发生干扰素加速反应以及提高对“细胞内”2-5P3A3的抑制细胞分裂活性的敏感性。对抗病毒细胞系干扰素基因表达的变异机理进行了讨论。

Serum samples collected from man, swine, rabbit, duck and chickenin West Sichuan in September 1979 were examined by haemagglutinationinhibition (HI) test for antibodies to human influenza A viruses(A(H_(sw1)N_1), A(H_1N_1), A(H_2N_2) and A(H_3N_2) ). The number ofthe samples tested from man and domestic sera were 114, 252, 84, 102,and 102 respectively, and some of the domestic sera positive with HIantibodies were retested by single radial haemolysis method (SRH) forfurther determination of whether the...

Serum samples collected from man, swine, rabbit, duck and chickenin West Sichuan in September 1979 were examined by haemagglutinationinhibition (HI) test for antibodies to human influenza A viruses(A(H_(sw1)N_1), A(H_1N_1), A(H_2N_2) and A(H_3N_2) ). The number ofthe samples tested from man and domestic sera were 114, 252, 84, 102,and 102 respectively, and some of the domestic sera positive with HIantibodies were retested by single radial haemolysis method (SRH) forfurther determination of whether the HI antibodies presented in HI testwere specific. Different sera showed different positive rates of HI anti-body to the four influenza antigens. Of the four subtypes, HI antibodiesin the swine sera HI antibody to the A(H_3N_2) antigen was the highest(17.5%), the presence of the antibody also was demonstrated by SRHmethod, The results suggested that not only in other countries but alsoin West Sichuan the influenza A virus (H_3N_2) already circulated amongthe swine population. HI antibody to the A(H_1N_1) antigen of the chick-en sera was 19.7%, two of 12 samples of positive sera by SRH test waspositive presumedly. The percentage and the level of all HI antibodies tothe four antigen of the rabbit sera were pretty high (25%, 98.8%, 98.8%and 90.4%) but by the SRH reaction no one of the positive sera showedthe evidence of any antibody. It suggested that the rabbit was possiblyuninfected with the human influenza A viruses.

本文报告用血凝抑制试验检查人和猪、鸭、鸡、兔血清中的人类流感病毒(A/Hsw_1N_1,A/H_1N_1,A/H_2N_2和A/H_3N_2)抗体,并用血抑抗体滴度较高的动物血清作单扩溶血试验复核,两种试验的结果悬殊很大,最后对这些结果的意义加以讨论。

 
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