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virus
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  肝炎病毒
    Study on the Relationship between Hepatitis C Virus and the Development of Chronic Hepatitis、Liver Cirrhosis、Primary Hepatic Carcinoma
    丙型肝炎病毒与慢性肝炎、肝硬变、原发性肝癌关系的研究
短句来源
    Detection hepatitis B virus antigen in liver cells from patients with hepatocellular carcinoma
    原发性肝细胞癌患者肝细胞中乙型肝炎病毒抗原的检测
短句来源
    INDUCING EFFECT OF HEPATITIS B VIRUS AND AFLATOXIN B_1 ON PRECANCEROUS LESION IN Tree Shrews LIVER
    乙型肝炎病毒与黄曲霉毒素B_1在树鼩肝癌癌前病变发生的作用
短句来源
    EFFECT OF DUCK HEPATITIS B VIRUS INFECTION ON AFLATOXIN-DNA-ADDUCTS FORMATION IN DUCK LIVER
    鸭乙型肝炎病毒感染对鸭肝中黄曲霉毒素-DNA加成物形成的影响
短句来源
    EFFECTS OF DUCK LIVER HEPATITIS B VIRUS ON DUCK LIVER CYTOCHROME P450
    鸭乙型肝炎病毒对肝脏细胞色素P450含量的影响
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  “virus”译为未确定词的双语例句
    Eeffacy of Acyclic Retinoid on the Fibroblast Growth Factor Mediated Signaling Pathways and Analysis on Hepatocelluar Genes of 19 Patients Infection with Hepatitis C Virus
    非环式维生素A对肝癌细胞纤维生长因子信号传导途径的影响及19例HCV感染者肝细胞遗传基因的初步分析
短句来源
    A Research for Malignant Transformation of Human Papillomavirus Type 16-immortalized Human Cervical Epithelial Cell by Defined Cloned DNA Fragments of Herpes Simplex Virus Type 2
    人单纯疱疹病毒Ⅱ型(HSV-2)转化片段恶性转化人乳头瘤病毒16型(HPV-16)永生化人宫颈鳞状上皮细胞的细胞生物学和分子生物学研究
短句来源
    An Experimental Study on the Gene Therapy for Human Gastric Carcinoma Using Wild-type P53 Gene and Herpes Simplex Virus Thymidine Kinase Gene
    外源性人野生型P53基因和单纯疱疹病毒的脱氧胸苷激酶基因治疗胃癌的实验研究
短句来源
    CHROMOSOME ABERRATIONS AND MORPHOLOGICAL CHANGES OF Hep-2 CELLS INDUCED BY ULTROVIOIET IRRADIAED HSV-2w VIRUS
    紫外线灭活的HSV-2地方株诱发Hep-2细胞的染色体畸变及形态变化
短句来源
    ANALYSIS OF THE EFFECTS OF PHYTOHEMAGGLUTININ (PHA) ON INDUCERS OF EPSTEIN-BARR VIRUS ANTIGENS AND DNA SYNTHESIS
    PHA对EBV抗原和DNA合成诱导物的作用的分析
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  virus
Human immunodeficiency virus type 1 (HIV-1) integrase is a potential target for anti-HIV therapy.
      
It is an essential enzyme required for replication of the acquired immunodeficiency syndrome (AIDS) virus.
      
Efavirenz is a trifluoromethylated inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) that shows good results in anti-HIV chemotherapy.
      
Derivatives on Herpes simplex virus type 1 (HSV-1), Mayaro virus (MAY) and vesicular stomatitis virus (VSV) were investigated.
      
Compounds 2d, 3f, 3a, and 3c exhibited antiviral activity against HSV-1, MAY, and VSV virus with EC50 values of 6.8, 2.2, 4.8, 0.52, 2.5, and 1.0.
      
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A serological mass survey was carried out in 9 communes of Cangwu county of Guangxi Zhuang Autonomous Region, sera from 91445 people of age 30 and over in the general population were tested for IgA antibody to EB virus VCA by immunoenzymatic method. Among the 91445 persons, 1183 had IgA antibody to VCA with a GMT of 1 : 20.6.The positive rate was 1293.67/100,000. 77,88% of the antibody-positive persons had IgA antibody titer of (?) 1 : 10. Among the 1183 antibody-positive persons, 28 cases were diagnosed...

A serological mass survey was carried out in 9 communes of Cangwu county of Guangxi Zhuang Autonomous Region, sera from 91445 people of age 30 and over in the general population were tested for IgA antibody to EB virus VCA by immunoenzymatic method. Among the 91445 persons, 1183 had IgA antibody to VCA with a GMT of 1 : 20.6.The positive rate was 1293.67/100,000. 77,88% of the antibody-positive persons had IgA antibody titer of (?) 1 : 10. Among the 1183 antibody-positive persons, 28 cases were diagnosed clinically and pathologically as nasopharyngeal carcinoma, 5 cases in stage Ⅰ, 12 in stage Ⅱ, 8 in stage Ⅲ and 3 in stage Ⅳ. The number of poorly differentiated squar-mous cell carcinoma, vesicular nucleus cell carcinoma and poorly differentiated adenocarcinoma were 21, 5 and 2 respectively. The results from twice serological mass surveys were also discussed. These results further confirmed that the immunoenzymatic method is useful for serological mass survey of nasopharyngeal carcinoma.

本文报告了用免疫酶法对广西苍梧县9个公社的91445人进行鼻咽癌血清学普查,VCA-IgA抗体阳性者1183人,阳性率1293.67/10万。抗体阳性者经临床和病理复查,发现鼻咽癌病人28例:Ⅰ期5例、Ⅱ期12例、Ⅲ期8例,Ⅳ期3例。低分化鳞癌、泡状核细胞癌和低分化腺癌分别为21、5和2例。作者还讨论了两次血清学普查的结果,再次证实免疫酶法用于鼻咽癌普查效果比较满意。

Exfoliated cells from nasoparynx of patients with definite or suspected nasopharyngeal carcinoma were examined for EBNA by anticomplement immunoenzymatic method. All 79 NPC patients were found to have EBNA-positive carcinoma cells, while the positive rates of cytological and histolog-ical examinations were 87.3 and 91.1% respectively. Tumor cells from other benign or malignant tumors of head and neck or nasopharyngeal epithelium from dead fetus were negative for EBNA. 6 cases with EBNA-positive cells and negative...

Exfoliated cells from nasoparynx of patients with definite or suspected nasopharyngeal carcinoma were examined for EBNA by anticomplement immunoenzymatic method. All 79 NPC patients were found to have EBNA-positive carcinoma cells, while the positive rates of cytological and histolog-ical examinations were 87.3 and 91.1% respectively. Tumor cells from other benign or malignant tumors of head and neck or nasopharyngeal epithelium from dead fetus were negative for EBNA. 6 cases with EBNA-positive cells and negative cytological or histological findings were reexamined 1 week to 5 months later and finally proved to have carcinoma.Thus,the anticomplement immunoenzymatic method is specific, sensitive and useful for the early detection of NPC. EBNA was found also in normal columnar epithelium or hyperplastic cell of nasopharynx. This suggest that NPC be caused by EB virus.

本文用抗补体免疫酶法检查鼻咽部脱落细胞的EBNA,结果①79例鼻咽癌病人全部阳性,其阳性检出率比细胞学(87.3%)和组织学(91.1%)方法高;②4例初次检查EBNA阳性,但细胞学和组织学阴性者,3个月内复查也找到癌细胞;③18例头颈部其他肿瘤病人和21例胎儿全部阴性,并为细胞学和组织学方法所证实。这表明抗补体免疫酶法检查EBNA是特异和敏感的,有助于鼻咽癌的早期诊断。除了在鼻咽癌细胞发现EBNA外,在鼻咽部柱状上皮细胞和增生细胞也发现EBNA,这可能与EB病毒引起的癌变过程有关。

The high risk center of nasopharyngeal carcinoma(NPC)was showed to be theboundary area of Guzhang,Baojing and Jishou in the Autonomous Region of WesternHunan by trend surface analysis.The age-adjusted mortality rates of NPC andgastric cancer at 103 counties and cities in Hunan Province were positively correlated,these two kinds of cancers therefore might have some common etiopathogeneticfactors.Among twelve mathematical functions,Weibull's distribution,log-normaldistribution and power equation were the best...

The high risk center of nasopharyngeal carcinoma(NPC)was showed to be theboundary area of Guzhang,Baojing and Jishou in the Autonomous Region of WesternHunan by trend surface analysis.The age-adjusted mortality rates of NPC andgastric cancer at 103 counties and cities in Hunan Province were positively correlated,these two kinds of cancers therefore might have some common etiopathogeneticfactors.Among twelve mathematical functions,Weibull's distribution,log-normaldistribution and power equation were the best functions fit to the mortality rates foreach age group of NPC.A three hits/multi-steps hypothesis of NPC carcinogenesiswas deduced from these analyses.The hypothesis suggests that the first hit is a kindof embryonic hit,heritable through multiple genes.The second hit is caused bychemical factors,such as nitrosamines,and followed by the third hit,i.e.EB virus,or vice versa.It also suggests that there are at least two or more steps in thecarcinogenic processes.

用趋势面分析法证明鼻咽癌的高发中心为湘西自治州的古丈、保靖和吉首三县交界区。湖南省103个县、市的鼻咽癌和胃癌的年龄调整死亡率间有正相关,因此这二种癌可能有某些共同的病因发病因素。在12种数学函数中,Weibull 分布、对数正态分布和幂方程对鼻咽癌的年龄组死亡率拟合最好。文中提出一个鼻咽癌变的三击/多步假说,假定第一击为胚性击中,通过多基因遗传;第二击由化学因素(如亚硝胺类)引起;继之第三击——EB 病毒,或二击为病毒而三击为化学因素。假说还认为癌变过程至少在二步以上。

 
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