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clinical
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  临床
    Evaluation of the Anal Sphincter Function Qualitatively and Quantitatively with Vector Manometry in Clinical Patients and Experimental Dogs
    直肠肛管向量测压定性定量评价肛门括约肌功能状态的临床与实验研究
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    Discussing the Pathogeny of GER and the Animal Experiment and Clinical Disquistion of the Gastric Bioelectrical Pace-maker Treatment
    GER动物模型制作及胃生物电起搏治疗的临床研究
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    Study on the Clinical Epidemiology of Children Diarrhea with Rotavirus Infection in Shanghai Area
    上海地区儿童腹泻轮状病毒感染的临床流行病学研究
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    Clinical Study on Infant Human Cytomegalovirus Hepatitis
    婴儿巨细胞病毒肝炎的临床研究
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    Clinical and Laboratory Studies of Childhood Acute Leukemia
    儿童急性白血病的临床与实验研究
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    NEONATAL CARDIAC ARRHYTHMIAS A Clinical Report of 8 Cases
    新生儿心律失常8例报告
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    Rotavirus Enteritis in Children an Clinical Analysis of 35 cases
    轮状病毒肠炎35例分析
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    A CLINICAL REPORT OF 19 CHILDREN OF CAMPYLOBACTER ENTERITIS
    小儿空肠弯曲菌肠炎19例报告
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    ATYPICAL CLINICAL MANIFESTATIONS OF HEMOLYTIC DISEASE IN THE NEWBORN (REPORT OF 8 CASES)
    新生儿溶血病的不典型表现(附8例报告)
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    Clinical efficacy of Albendazole in the treatment of 80 cases of enterobiasis in children
    丙硫咪唑治疗儿童蛲虫病80例效果观察
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  clinical
Guanidine-type compounds that reached clinical status include amongst others the potassium channel opener, pinacidil and the histamine H2-receptor antagonists (e.g.
      
(ii) Other compounds have proceeded through preclinical and/or clinical development: CXCR4 antagonists (i.e.
      
(iii) Yet other compounds, acting by novel mechanisms, have recently been identified as anti-HIV agents that seem worthy of further (pre)clinical development: cell receptor CD4 downmodulators (i.e.
      
PRE-CLINICAL AND CLINICAL PHARMACOKINETICS OF THE DIASTEREOMERS OF ARTEETHER, A POTENT ANTIMALARIAL
      
Pre-clinical studies were carried out (N=3) by oral, intramuscular and intravenous routes, while clinical studies (N=13) were performed intramuscularly.
      
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On the basis of observations of 131 autopsies on newborn babies, we found that pulmonary affections and intrauterine asphyxia were the two most common causes of death with major malformations ranking next and intracranial hemorrhage the third. Prematurity constituted 51% of the uncorrected perinatal mortality under study. It was felt that death in these babies were due to incomplete development of vital organs especially of lungs resulting in anoxia or interference with circulation. In order to profit by experiences...

On the basis of observations of 131 autopsies on newborn babies, we found that pulmonary affections and intrauterine asphyxia were the two most common causes of death with major malformations ranking next and intracranial hemorrhage the third. Prematurity constituted 51% of the uncorrected perinatal mortality under study. It was felt that death in these babies were due to incomplete development of vital organs especially of lungs resulting in anoxia or interference with circulation. In order to profit by experiences and to reduce further the death rate of newborn babies, it is essential that the cause or causes of death in each case must be ascertained through a careful correlation of findings of autopsy examination with clinical data which might have influenced its perinatal mortality. The relevant clinical data could be maternal complications during pregnancy or during labor, condition of the baby at time of delivery or the kind of treatment and nursing care the newborn baby received. The authors of the present series agree with other investigators that anoxia and intracranial hemorrhage not only predispose to, but also aggravate, each other. For intrauterine death, examination should always include the placenta.

1.本文分析131例新生儿尸体解剖死亡原因,其中以肺综合症及胎内窒息占最高发生率,畸形及顱内出血分别占第二位及第三位。 2.新生儿尸体解剖例中早产儿占51.2%;病变主要在肺脏,引起呼吸衰竭死亡;原因大部为缺氧或循环障碍。检查新生儿死亡之因素应包括胎盘的情况,妊娠各期及产程内母体情况和胎儿情况胎儿出生后之情况、以及上述各时期中之护理情况。

Clinical analysis of 120 cases of myocarditis following virus infection were undertaken during 1970~1977. According to the manifold clinical characteristics, classfication of the disease into two groups and five types, which plays an important part in the prognosis of this disease, was suggested. The cardiographic changes, charaterized by their variability senitivity, and unstability which are helpful for early diagnosis and prognosis, are important diagnostic criteria of myocarditis. Although there was...

Clinical analysis of 120 cases of myocarditis following virus infection were undertaken during 1970~1977. According to the manifold clinical characteristics, classfication of the disease into two groups and five types, which plays an important part in the prognosis of this disease, was suggested. The cardiographic changes, charaterized by their variability senitivity, and unstability which are helpful for early diagnosis and prognosis, are important diagnostic criteria of myocarditis. Although there was still no specific and effective therapeutic measure for the disease. however in our experience, the effect of using large amount of high concentrated vitamin C in rescuing cardiogenic shock was evidenced.

本文总结了1970~1977年收治的120例病毒性心肌炎的临床随诊资料。根据120例资料分析,提出分组分型的看法及其与预后的关系。认为心电图是诊断心肌炎的重要依据。心肌炎心电图的多样性、多变性,敏锐性的特点对早期诊断和判断病情有一定帮助。维生素C对抢救急性心源性休克有一定作用。

According to the servey of rickets in children under 3 years of agecarried out in Chengdu in the winter of 1977 and spring of 1978 as apart of the investigation in our country, the incidence of rickets ofSichuan children was 27%, while in the other parts of our country itranged from 15-50%. In this series, most of them were in mild form.Characteristic symptoms and signs, blood biochemical changes such asmicromethod for the detection of active metabolite of vitamin D(25-hydroxycholecalciferol-25 OHD), and osseous...

According to the servey of rickets in children under 3 years of agecarried out in Chengdu in the winter of 1977 and spring of 1978 as apart of the investigation in our country, the incidence of rickets ofSichuan children was 27%, while in the other parts of our country itranged from 15-50%. In this series, most of them were in mild form.Characteristic symptoms and signs, blood biochemical changes such asmicromethod for the detection of active metabolite of vitamin D(25-hydroxycholecalciferol-25 OHD), and osseous roentgenographic abnor-malities are used in the diagnosis of rickets, but the latter two examinations are not easily available in the county and countryside hospitals. Therefore,on the basis of the clinical data of this servey, a simplified scheme forthe diagnosis and treatment of rickets in children has been proposed. Itconsists of three parts: 1. Predisposing factors and prevention: The authors' and other datarevealed that prematurity, twins, rapid growth, lack of sunshine, artificialfeeding and infant under one year of age were found to be more prone torickets. Preventive doses of vitamin D should be administered to them. 2. Symptoms, signs and diagnosis: In a careful statistical analysisof the clinical manifestaions, biochemical and roentgenographic changesof 378 children with rickets and 233 children without rickets, the authorsfound that: (1) The so-called early symptoms such as increased sweating,muscular irritability and restlessness seemed not to be specific. Fromtherapeutic test, it seemed that muscular irritability was of some diagnosticvalue. (2) The most characteristic osseous changes were craniotabes,alopecia of the occipital region, enlarged anterior fontanel and flaring outof the costal margins. (3) Ricketic rossary, bowlegs and ricketic spinalcurvature seemed to have certain diagnostic value, while other osseouschanges showed no diagnostic value for active rickets. 3. Vitamin D therapy for active rickets: A total dose of 900,000-1,200,000 IU of vitamin D, divided into 2-3 doses intramuscularly onceevery manth, was found to be more effective than smaller doses. This scheme of simplified diagnosis of rickets in children under threeyears of age had been found to be accurate in about 70% as comparedwith the rational methods of diagnosis.

作者通过对普查的2,123名乳幼儿中经临床表现、血清生化及x线腕部摄片三项检查确诊为佝偻病患儿378名及无佝偻病者233名对比分析,探讨了三项检查联合应用的确诊率;单项检查对诊断本病的可靠程度以及用不同剂量维生素D治疗后观察症状体征、血清生化及x线改变等的恢复情况,寻出有效的维生素D治疗量和提出对本病的简易诊治标准,以供参考。

 
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