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clinical
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  临床
    Clinical and Molecular Genetic Study of Dopa-responsive Dystonia
    多巴敏感性肌张力障碍临床和分子遗传学研究
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    The Clinical and Neuropathological Study in Patients with Cerebral Amyloid Angiopathy
    淀粉样脑血管病的临床和神经病理学研究
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    Studies on Clinical and Biological Behaviors and Anatomic Comparative Surgical Approaches of Median Skull Base Tumor
    中间颅底肿瘤临床生物学行为及手术入路解剖比较研究
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    The Experimental and Clinical Study on Neuron Functional Imaging for Parkinson's Disease
    帕金森病的实验和临床神经功能影像学研究
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    Experimental and Clinical Application of MR Functional Techniques in the Study of Cerebral Gliomas
    脑胶质瘤磁共振功能成像的实验与临床应用研究
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    Clinical Applications of Quantitative Sensory Testing in Neuropathy
    定量感觉检查在周围神经病中的应用
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    Clinical Applications of PET Brain Imaging in the Diagnosis of Cerebral Infarction and Brain Tumors
    PET脑显像在脑梗塞和脑瘤诊断中的应用
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    ANALYSIS OF CLINICAL MANIFESTAION AND EEG IN 500 CASES OF EPILEPTICS UNDER 16 YEARS OLD
    500例16岁以下癫痫患者的脑电图与发作类型分析
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    CLINICAL STUDY ON THE DETERMINATION OF FIBRINOLYSODYNAMICOGRAM AND α_2-MACROGLOBULIN IN THE ACUTE STAGE OF CEREBRAL VESSEL DISEASE
    脑血管病急性期纤溶活性动态图和α_2-巨球蛋白测定
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    CLINICAL OBSERVATION OF SVATE ON 34 CASES OF THROMBOSIS AND CONCENTRATION OF TXB_2 6-keto-FGF_(1α)
    江浙蝮蛇抗栓酶对脑血栓形成患者血浆TXB_2、6-KeTo-PGF_(1α)水平的影响
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  clinical
Guanidine-type compounds that reached clinical status include amongst others the potassium channel opener, pinacidil and the histamine H2-receptor antagonists (e.g.
      
(ii) Other compounds have proceeded through preclinical and/or clinical development: CXCR4 antagonists (i.e.
      
(iii) Yet other compounds, acting by novel mechanisms, have recently been identified as anti-HIV agents that seem worthy of further (pre)clinical development: cell receptor CD4 downmodulators (i.e.
      
PRE-CLINICAL AND CLINICAL PHARMACOKINETICS OF THE DIASTEREOMERS OF ARTEETHER, A POTENT ANTIMALARIAL
      
Pre-clinical studies were carried out (N=3) by oral, intramuscular and intravenous routes, while clinical studies (N=13) were performed intramuscularly.
      
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This is a clinico-electroencephalographic report of seven typical cases of subacute sclerosing panencephalitis with a discussion of certain aspects of the disease. Correct and early diagnosis of the disease hinges on the total clinical picture rather than any isolated symptom or/and sign. The diagnosis of this disease is more aptly established if the case is associated with fairly typical EEG findings, biochemical and immunological studies of the blood and spinal fluid and morphological findings of the...

This is a clinico-electroencephalographic report of seven typical cases of subacute sclerosing panencephalitis with a discussion of certain aspects of the disease. Correct and early diagnosis of the disease hinges on the total clinical picture rather than any isolated symptom or/and sign. The diagnosis of this disease is more aptly established if the case is associated with fairly typical EEG findings, biochemical and immunological studies of the blood and spinal fluid and morphological findings of the biopsied specimen of the brain. Case 2 was a boy of 7 years old who had been noted to have speech difficulty and memory defect for several months and one generalized seizure the day before he was seen on Feb. 8, 1977. Under the treatment of anticonvulsants and steroids he apparently had two periods of remission. He contracted measles two years after the onset of his illness but without evident symptoms. Case 6 had been treated in a mental hospital as a case of schizophrenia. The corrent diagnosis in this case was made on the basis of the total clinical picture and EEG findings. Anticonvulsants , cytoarabinose , amantadine , steriod , supportive measures and good nursing care have made him more alert and improved his general condition to the satisfaction of his family though he is still demented. Both these two cases had had serial EEG examinations.

本文报告了临床和脑电图?见

155 cases of sporadic encephalitis are reported. Among these cases,13 were autopsied. This is a disorder characterized by diverse impairmentsof the central nervous system such as psychiatric disturbance, unconsci-ousness, epilepsy, paralysis, decortical state, etc. In the majority ofthe subjects studies, infectious features were not prominent and therewere no changes in the cerebral spinal fluid. However, in a few cases,slight pleocytosis with a mild increase of protein in the CSF or slightincrease of the intracranial...

155 cases of sporadic encephalitis are reported. Among these cases,13 were autopsied. This is a disorder characterized by diverse impairmentsof the central nervous system such as psychiatric disturbance, unconsci-ousness, epilepsy, paralysis, decortical state, etc. In the majority ofthe subjects studies, infectious features were not prominent and therewere no changes in the cerebral spinal fluid. However, in a few cases,slight pleocytosis with a mild increase of protein in the CSF or slightincrease of the intracranial pressure was recorded. On the basis of the clinical manifestation, these cases were dividedinto five groups: (1) psychiatric type, (2) intracranial hypertension type,(3) epileptic type, (4) protean clinical manifestation type, and (5) para-lytic type. On pathological examination, two forms were observed. Onewas compatible with virus encephalitis, while another with demyelinateencephalitis. However, pathologically these two forms could be clearlydistinguished, but clinically they were not. It is assumed that sporadic encephalitis may be resulted from morethan one cause. The diagnosis and elucidation of the nature of thedisease need further investigation.

本文报告散发性脑炎155例,其中13例进行尸解,发现有两类病理改变,一种符合病毒性脑炎;另一种符合急性脱髓鞘性脑炎。两种病例在临床上不易鉴别。因此,对本病的诊断有待从病原学,免疫学及电镜检查等方面进行探索。

Sturge-Weber syndrome is a congenital disorder with a familial tendency and an irregular dominant heredity. Clinically it is characterized by the presence of cutaneous vascular nevi, convulsive seizures, mental disturbances, buphthalmus, spastic hemiplegia and one-sided hypotrophy of extremites. Roentgenologically intracranial patches or double-contour wavy shadows or multiple flecks are seen in the skull. Pneumoencephalograms reveal atrophy of cerebral hemisphere and dilatation of lateral ventricles of the...

Sturge-Weber syndrome is a congenital disorder with a familial tendency and an irregular dominant heredity. Clinically it is characterized by the presence of cutaneous vascular nevi, convulsive seizures, mental disturbances, buphthalmus, spastic hemiplegia and one-sided hypotrophy of extremites. Roentgenologically intracranial patches or double-contour wavy shadows or multiple flecks are seen in the skull. Pneumoencephalograms reveal atrophy of cerebral hemisphere and dilatation of lateral ventricles of the corresponding side. Electroencephalographic studies show reduction in amplitude, sharp wave or slow wave focus on the same side as the cutaneous vascular nevi. Pathologically angiomatous changes of face and meninges, calcification in cortical layer and cerebral capillary wall, diminution of ganglion cells and gliosis are evident. The present article is a clinical analysis of 22 cases seen in 1936~1978, Three illustrative cases are appended.

Sturge-Weber二氏综合征是先天性疾患,似属显性遗传。临床上以皮肤血管痣、搐搦发作、精神症状、眼球突出、痉挛性偏瘫及半身萎缩为特征。颅骨片于枕部示片状或双层波状钙化灶。气脑造影示相应侧大脑半球脑沟增宽及脑室扩大。病理方面皮肤及脑膜有血管痣,脑皮质有钙化灶,神经细胞减少及胶质细胞增生。脑电图常有一侧波幅降低或尖波慢波灶。神经精神症状系脑膜血管瘤压迫所致。本病散见于世界各种族。作者将1936~1978年所见之22例作了临床分析。并附3例病历摘要。

 
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