Biomimetic strengthening polylactide scaffold materials for bone tissue engineering
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The novel composite mainly consists of nano-hydroxyapatite (n-HA), which is the main inorganic content in natural bone tissue for the PLA.
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The crystal degree of the n-HA in the composite is low and the crystal size is very small, which is similar to that of natural bone.
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The biomimetic three-dimensional porous composite can serve as a kind of excellent scaffold material for bone tissue engineering because of its microstructure and properties.
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The effects of hematopoietic stem/progenitor cells (HSPCs) expanded in the two step coculture with human bone marrow mesenchymal stem cells (hMSCs) on the hematopoietic reconstruction of irradiated NOD/SCID mice were studied.
23 cases (4.09%) of intussusception were observed in 562 dogs succumbed to acute radiation sickness or combination with burn and blast injury.All intussusception cases were seen in dogs died of bone marrow death and intestinal death,but not in central nervous system death or immediate rediation death. In treated animals the incidence of intussusception was 6.36%(14/220 cases) while in controls only 2.63%(9/342 cases).The incidence of intussusception in radiation sickness was 0.61%(1/164 cases) and inc...
A number of 180—200 gram healthy adult rats were dividedinto two groups.One group were simply irradiated with various doses(100—600 fads)of ~(60)Co γ-rays,and the other group were exposed to samedosage of γ-rays in eombination with 15% 2nd degree burns.The incidenceof chromosomal aberrations in cells of bone marrow of both groups of ratswere examined 24 hours later.The incidence of all type of chromosomalaberrations between simple burn group and the control group,between theirradiation-burn group and ...
On September 1, 1980, a 25-year old worker was accidently exposed by a high-intensity 60Co source of approximate 206X1013Bq. An acute bone marrow -type radiation sickness was observed after an accidental nonuniform g&mme ?ray irradiation. The estimated equivalent whole-boby uniform irradiation close was 5.22 Gy. The patient survived and was followed up for a period of 8 years from 1981 to 1983.The patient has been recalled at intervals of one year for routine examinations and hematological, biochemica...