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   micro bubble 在 药学 分类中 的翻译结果: 查询用时:0.17秒
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micro bubble
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  micro bubble
Window of type I micro bubble formation is indicated with onset at 52 seconds and off set at 58 seconds.
      
The periodic micro-bubble agitation in the static hybridization solution could effectively mix the molecular beacon and the beacon complements.
      
The hybridization assay without the micro-bubble actuation revealed that the fluorescence increased fast at the beginning and slowed down after that.
      
The fabricated micro-bubble actuator array was tested in the hybridization buffer.
      
The fabrication of the micro-bubble actuator array followed the conventional MEMS technology.
      
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Objective To study in contrast the enhancements of blood flow or grey scale of tissue and organs by using two kinds of China-made ultrasonic contrast agents containing fluoro-carbon micro bubbles.Methods The contrast agents were "Quanfuxian" and "FX530".The enhancements of grey scale and blood flow of the livers or kidneys of the normal rabbits or dogs were observed after intravenous bolus injection.The visual contrast effects of grey scale were estimated as 4 grades.Results Both contrast agents could...

Objective To study in contrast the enhancements of blood flow or grey scale of tissue and organs by using two kinds of China-made ultrasonic contrast agents containing fluoro-carbon micro bubbles.Methods The contrast agents were "Quanfuxian" and "FX530".The enhancements of grey scale and blood flow of the livers or kidneys of the normal rabbits or dogs were observed after intravenous bolus injection.The visual contrast effects of grey scale were estimated as 4 grades.Results Both contrast agents could enhance color blood flow of the livers and kidneys and caused obviously "color blooming".After injecting "Quanfuxian" the grey scale of blood vessels was enhanced,or the hepatic parenchyma was enhanced uniformly when observed by transient respond imaging.The grey scale of the hepatic parenchyma could be enhanced with fundamental imaging after administration of "FX530".The grey scale enhancement of the renal parenchyma was produced after injection of either of the two agents.Conclusions The two kinds of China-made ultrasonic contrast agents could be used to assess perfusion of tissue and organs.They are ideal ultrasonic contrast agents at present.

目的 探讨两种国产氟碳类微气泡声学造影剂“全氟显”和“FX5 30”增强组织器官彩色血流及组织灰阶图像的特点。方法 声学造影剂为“全氟显”和“FX5 30” ,经外周静脉团注 ,观察正常犬或兔肝脏、肾脏的组织灰阶或彩色多普勒血流增强。灰阶增强依视觉效果分为 4级。结果 两种造影剂均可使肝脏和肾脏的彩色血流增强并有明显的彩色溢出现象。“全氟显”使肝脏血管的灰阶图像增强 ,应用瞬间反应成像观察则可见肝实质回声均匀增强。“FX5 30”在基波超声观察下使肝脏实质灰阶图像增强。两种造影剂均可使肾实质的组织灰阶图像均匀增强 ,使肾实质的彩色血流增强并产生明显的彩色溢出。结论 两种国产氟碳类微气泡声学造影剂均可用于观察组织器官血流灌注情况 ,是目前较为理想的声学造影剂。

The ultrasonic contrast agents(UCA) may be used in tumor therapy when UCA is irradiated by a low frequency ultrasound based on bubble cavitation and other nonlinear effects.Therefore study of UCA dynamic characteristics at low frequencies is necessary.The motion equa-tion describing spherical oscillation of a coated microbubble in an incompressible and weak viscosity liquid is derived from the Lagrangian equation with dissipation function when the microbubble is considered as loaded nonlinear vibrator...

The ultrasonic contrast agents(UCA) may be used in tumor therapy when UCA is irradiated by a low frequency ultrasound based on bubble cavitation and other nonlinear effects.Therefore study of UCA dynamic characteristics at low frequencies is necessary.The motion equa-tion describing spherical oscillation of a coated microbubble in an incompressible and weak viscosity liquid is derived from the Lagrangian equation with dissipation function when the microbubble is considered as loaded nonlinear vibrator with its incompressible shell in liquid at low frequencies.The scatterred light I(t) curves of CO2 microbubble and perfluoropropane(C3F8) microbubble with an albumine shell are measured with spherical resonant cell and laser Mie scattering technique,in good agreement with simulation results.It shows that coated UCA micro-bubbles undergo expanding collapsing and rebounding three phases in stable cavitation,such as free microbubbles.In transient cavitation,two kinds of bubble will expand to dozens,even hund-reds,of their original sizes,and break into fragments in few cycles under not very high acoustic pressure.In either case,micro blood vessels in tumors will be injured,which will lead to blood-clot formation.

低频超声联合微泡造影剂有可能用于治疗肿瘤,因此开展造影剂低频的动力学特性研究是十分重要的。将低频声场(26.2kHz)中有壳和无壳的微泡造影剂视为以流体为负载的非线性振子,由带耗散函数的拉格朗日方程导出在不可压缩的粘滞流体中造影剂球对称振动的运动方程,利用球谐振腔和Mie散射技术对CO2微泡和带人白蛋白壳的全氟丙烷造影剂微泡进行了气泡散射光强I(t)曲线的实验测定,结果与数值模拟曲线相一致。表明:有壳和无壳的造影剂微泡在低频稳态空化时同样呈现大幅膨胀、迅速塌缩和回弹的非线性振荡;如处于内径较小的微血管中,微泡周期性大幅度(>血管内径)膨胀收缩将会引起血管轴向破裂,形成微血管栓塞;而在塌缩相,微泡内的气体被急剧压缩,泡内压强急剧增大,易在泡壁不稳定处形成高速微射流,诱发内皮细胞损伤而形成血栓。

 
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