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heart     
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  心脏
    A Study on Catastrophe Characteristics Analysis of Heart Beating and Its Applications Based on Electrobiology
    基于电生理的心脏搏动突变性分析和应用研究
短句来源
    Effects of Atorvastatin on the MMPs/TIMPs and NF-κB of SHR Cardiac Fibroblasts and Its Role in the Pathogenesis of Heart Remodeling
    阿伐他汀调控SHR心脏成纤维细胞MMPs/TIMPs和NF-κB表达及其与心脏重塑关系的研究
短句来源
    Heart Fatty Acid Binding Protein as a Marker for Postmortem Diagnosis of Acute Myocardial Infarction
    心脏型脂肪酸结合蛋白诊断早期心肌梗死的研究
短句来源
    Experiment Study of Cardiac Resynchronization Pacing with Different Sites Combination on Chronic Ischemic Heart Failure
    不同位点组合心脏再同步起搏治疗慢性缺血性心力衰竭的实验研究
短句来源
    Researches on TBX1 Gene with Human Simple Conotruncal Heart Malformation
    TBX1基因与人类单纯性心脏圆锥动脉干畸形的相关研究
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    Study of both excitation condution of muscle strip of frog heart and the potential distribution of the frog heart in liquid media
    蛙肌条兴奋传递及蛙电位在液态介质中分布的研究
短句来源
    Effects of Valsartan and Spironolactone on Matrix Metalloproteinases, Collagen Metabolism and Heart Function in Post-myocardial Infarction
    缬沙坦和安体舒通对急性肌梗死后基质金属蛋白酶和胶原代谢以及功能的影响
短句来源
    Mechanisms of Myocardial Energy Metabolic Disorders Responsible for Left Heart Failure Initiated by Lung Infection in Elderly Canines
    老龄犬肺部感染启动左衰竭肌能量代谢障碍的机制研究
短句来源
    Effect of Angiotensin Ⅱ Receptor Blockers on Calcium Regulation in Isolated Ventricular Myocytes of Rats from Heart Failure
    血管紧张素Ⅱ受体拮抗剂对力衰竭肌细胞钙调控的影响
短句来源
    Geometric and Functional Remodeling as Well as Its Influential Factors of Atherosclerotic Coronary Arteries and Left Heart in Hypertension and Atrial Fibrillation
    粥样硬化冠状动脉、高血压与房颤左几何与功能重塑及其影响因素
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  心肌
    Study of both excitation condution of muscle strip of frog heart and the potential distribution of the frog heart in liquid media
    蛙心肌条兴奋传递及蛙心电位在液态介质中分布的研究
短句来源
    The Protection of Phosphocreatine on the Function of Rat of Myocardial Hypertrophy and Heart Failure
    磷酸肌酸对心肌肥厚及心力衰竭大鼠心肌的保护作用
短句来源
    Relation of Activation of Nuclear Factor-κB to Cardiomyocyte Apoptosis and Effects of Carvedilol During Heart Failure Subsequent to Myocardial Infarction in Rats
    核因子-κB活化与心衰大鼠心肌细胞凋亡的关系及卡维地洛干预的影响
短句来源
    The Animal Experiment and Clinical Study of Neurohomoral Activation and Myosin Expression in Congestive Heart Failure
    充血性心力衰竭与儿茶酚胺-β受体系统关系及心肌肌球蛋白基因表达的实验和临床研究
短句来源
    Lipopolisaccharide-Induced Cardiac Inflammation and Left Ventricular Dysfunction: Role of Toll-Like Receptor-4 in the Adult Heart
    Toll样受体4在内毒素诱导的小鼠心肌炎症因子表达和左室功能不全中的作用
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  心脏病
    The Relationship between Mannose-binding Lectin (MBL) and Rheumatic Heart Disease and Recombinant MBL Protein Expression
    甘露糖结合凝集素与风湿性心脏病的关系及其重组蛋白的表达
短句来源
    Study on Mechanisms Responsible for Myocardial Fibrosis in Viral Heart Diseases and Its Pharmaceutical Intervention
    病毒性心脏病心肌纤维化的发生机制及其药物干预研究
短句来源
    Study on Electrophysiological Mechinism and Calpain Ⅰ Changes of Atrial Fibrillation in Rheumatic Heart Diseases
    风湿性心脏病心房颤动的电生理机制及Calpain Ⅰ的作用机制研究
短句来源
    1,TBX5 Gene and Cardiac Development 2,Analysis of SNP and Haplotype in HOXC Gene Cluster Within Susceptible Region 12q13 of Simple Congenital Heart Disease
    一、TBX5基因与心脏发育 二、单纯性先天性心脏病易感区域12q13内HOXC簇基因SNP单体型分析
短句来源
    Research for Associated Gene of Congenital Heart Disease
    先天性心脏病相关基因研究
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      heart
    The synthesized compounds were evaluated as perchlorides and methiodides by functional tests with rabbit vas deferens (putative M1), guinea-pig heart (M2) and guinea-pig ileum (M3).
          
    The synthesized compounds were evaluated as perchlorides and methiodides by functional tests with rabit vas deferens (putatvie M1), guinea-pig heart (M2) and guinea-pig ileum (M3).
          
    These proteins may be involved in cardiovascular injury, and could play an important role in the treatment of coronary heart disease.
          
    Twenty cases still had other congenital heart diseases: ventricular septal defect (19 cases), patent ductus arteriosus (two cases), double-chambered right ventricle (one case), aneurysm of the right anterior aortic sinus of valsalva (three cases).
          
    Congenital aortic valve malformations in children involve males more than females, mostly associated with other congenital heart diseases.
          
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    The clinical features of 415 attacks of rheumatic fever observed in 365 adult patients are described, and some of the diagnostic problems are discussed, 102 of the attacks were considered to be initial and 313 recurrent attacks. Pre-existing chronic valvular disease was diagnosed in 184 cases. The attack rate of rheumatic fever by season was found to be highest in late Winter and Spring, with the peak incidence in the months of March and April. A history of preceding sore throat was elicited in 41% of the rheumatic...

    The clinical features of 415 attacks of rheumatic fever observed in 365 adult patients are described, and some of the diagnostic problems are discussed, 102 of the attacks were considered to be initial and 313 recurrent attacks. Pre-existing chronic valvular disease was diagnosed in 184 cases. The attack rate of rheumatic fever by season was found to be highest in late Winter and Spring, with the peak incidence in the months of March and April. A history of preceding sore throat was elicited in 41% of the rheumatic attacks, and inflammatory signs in the pharynx and tonsils were observed in 58.6% of the attacks. The antistreptolysin O titer was above 250 units in 80% of the cases examined. Among the clinical manifestations arthritis and carditis were most common, occurring in 55.7% and 49.9% respectively, while arthralgia without frank inflammatory signs was noted in 30% of the attacks. The incidence of arthritis was lower in the cases with chronic valvular defects than in cases without. In 29% of the cases ECG abnormalities constituted the sole clinical evidence of carditis. Since prolongation of P-R interval or higher grades of atrioventricular block are relatively common in rheumatic fever and other manifestations of rheumatic carditis like murmurs, cardiac enlargement, pericarditis and heart failure are equally non-speclfic, it is suggested that a-v block be included as evidence of carditis rather than considered as a minor manifestation if one adopts Jones' criteria for the diagnosis of rheumatic fever. In the presence of chronic valvular disease frank arthritis was uncommon and signs of carditis were often masked by those of valvular defects so that in 38.5% of cases the diagnosis of rheumatic activity had to depend upon a combination of clinical and laboratory signs generally concidered as minor rheumatic manifestations according to Jones' criteria.

    1.本文报告成人急性风湿热366例,經住院观察的急性发作共415次,其中102次診断为初发,313次为复发。发作見于已有慢性心瓣缺损者計184例(218次发作),无心瓣缺损証据者182例(197次发作)。对发病季节、与溶血性鏈球菌感染的关系、临床表現、实验室发見、病程及病死率等作了分析。重点討論了本病的診断问題。 2.风湿热在春冬二季的发病率較高,41%的风湿发作前有咽痛,58.6%的风湿发作时咽部尚有炎症表現,仅24.7%的风湿发作前后均无咽炎的証据。約有80%发作中抗鏈球菌溶血素“O”滴定度在250单位以上。以上数字有力地說明了风湿热和鏈球菌感染之间的密切关系。 3.临床表現中以关节炎最为常見,发生率为55.7%,仅有关节酸痛的有30%。已有慢性心瓣缺损的病例中仅37.6%有关节炎,其发生率远低于无慢性心瓣缺损的病例(75.6%)。 4.心炎見于49.9%的发作中,其临床表現有时颇不明显。仅在心电图檢查中发見者有41例,占所有經过心电图檢查的心炎病例的29%。由此可見心电图检查对診断心炎的独特价值。 5.在曾作心电图檢查的250次发作中有82次(32.8%)发見房窒傳导阻滞,其中68次为P-R间期延长。作...

    1.本文报告成人急性风湿热366例,經住院观察的急性发作共415次,其中102次診断为初发,313次为复发。发作見于已有慢性心瓣缺损者計184例(218次发作),无心瓣缺损証据者182例(197次发作)。对发病季节、与溶血性鏈球菌感染的关系、临床表現、实验室发見、病程及病死率等作了分析。重点討論了本病的診断问題。 2.风湿热在春冬二季的发病率較高,41%的风湿发作前有咽痛,58.6%的风湿发作时咽部尚有炎症表現,仅24.7%的风湿发作前后均无咽炎的証据。約有80%发作中抗鏈球菌溶血素“O”滴定度在250单位以上。以上数字有力地說明了风湿热和鏈球菌感染之间的密切关系。 3.临床表現中以关节炎最为常見,发生率为55.7%,仅有关节酸痛的有30%。已有慢性心瓣缺损的病例中仅37.6%有关节炎,其发生率远低于无慢性心瓣缺损的病例(75.6%)。 4.心炎見于49.9%的发作中,其临床表現有时颇不明显。仅在心电图檢查中发見者有41例,占所有經过心电图檢查的心炎病例的29%。由此可見心电图检查对診断心炎的独特价值。 5.在曾作心电图檢查的250次发作中有82次(32.8%)发見房窒傳导阻滞,其中68次为P-R间期延长。作者等认为,P-R间期延长或更高度的房室傳导阻滞,若发見于有鏈球菌感染之后的年青患者,应作为急性风湿性心炎的診断依据之一。 6.在已有慢性心瓣病的病例中,有38.5%得根据Jones氏診断标准中的几項次要表現而診断为风湿活动。 7.366例中58.5%有风湿热的复发,其中半数发生子初发以后的第一年內。住院期的当时病死率为6.5%。

    (1)In the chloralose-urethanized or curarized rabbits,infusion of saline or blood into the right auricle in amount of 8—10 ml/kg at the rate of 0.5—1.0 ml/sec induced bradycardia and hypotension. (2)Section of sino-aortic nerves and bilateral vagotomy did not alter the negative chronotropic effect due to auricular infusion,thus indicating that a local mechanism was responsible for the effect. (3)Distension of the right auricle by inflating an indwelling balloon with various pressures(20—70 mm Hg)also evoked...

    (1)In the chloralose-urethanized or curarized rabbits,infusion of saline or blood into the right auricle in amount of 8—10 ml/kg at the rate of 0.5—1.0 ml/sec induced bradycardia and hypotension. (2)Section of sino-aortic nerves and bilateral vagotomy did not alter the negative chronotropic effect due to auricular infusion,thus indicating that a local mechanism was responsible for the effect. (3)Distension of the right auricle by inflating an indwelling balloon with various pressures(20—70 mm Hg)also evoked bradyeardia which persisted after cutting the vagi.Plotting the change in heart rate against pressure within the balloon,a non- linear relationship was revealed.The bradycardia observed could not be attributed to anoxemia resulting from reduced venous return,since the temporary occlusion of superior and inferior venae cavae failed to evoke bradycardia. (4)The blockage of sino-auricular node by local novocaine infiltration as well as by local or general hypothermia(26—28℃)abolished the negative chronotropio res- ponse to the atrial infusion.Therefore it was suggested that such a response occurred as a result of alteration in the functional state of sino-auricular node. (5)Under our experimental conditions,the cardiac acceleration reflex originally found by Bainbridge could not be demonstrated in the rabbits.

    (一)在氯醛糖和氨基甲酸乙酯麻醉的兔或未麻醉的箭毒化兔,右心房内输液(输入量为8—10毫升/公斤,输入速度为0.5—1.0毫升/秒),可规律地引起心率减慢和动脉血压下降。(二)右心房输液引起的心率变化,在切断两对缓冲神经和迷走神经后并不消失,说明此种输液效应并非反射作用。(三)经颈外静脉向右心房内引入一小气囊,以不同压力扩张后,也可导致心率减慢。此时气囊内压值与心率变化之间的关系不是完全呈直线式的。切断迷走神经后,效应仍存在;且此效应也不是由于气囊扩张阻断血液回流所致。(四)以奴佛卡因溶液阻断窦房结区后,右心房输液不再引起心率减慢。全身低温或选择性心脏低温(26—28℃)后,大多数实验中的心率在输液后不再变慢,由此说明右心房内输液对心率的影响是刺激直接作用于窦房结而改变其机能活动的结果。(五)在我们的实验条件下,从兔身上不能证示有 Bainbridge 反射的存在。

    Intracardiac phonocardiography was studied both in human beings and animals.The local- made microphone sealed in the tip of a Courn- and's cardiac catheter was used.The phonocar- diogram was recorded through N.E.P.mul- tichannel physiological recorder. Ten noncardiac patients were subjected to the study.To each of them a No.7 phonoca- theter was inserted through the peripheral vein to the right heart.Heart sounds were recorded in the pulmonary artery,the right ventricle and the right auricle.Ordinary...

    Intracardiac phonocardiography was studied both in human beings and animals.The local- made microphone sealed in the tip of a Courn- and's cardiac catheter was used.The phonocar- diogram was recorded through N.E.P.mul- tichannel physiological recorder. Ten noncardiac patients were subjected to the study.To each of them a No.7 phonoca- theter was inserted through the peripheral vein to the right heart.Heart sounds were recorded in the pulmonary artery,the right ventricle and the right auricle.Ordinary phonocardiogram, limb leads electrocardiogram and carotid pulse tracing were recorded simultaneously.In the animal study,ten dogs were used.Under ex- perimental condition,eight dogs had their hearts exposed through open-chest,No.4 or No.7 phonocatheter was inserted in each heart cham- ber,the ascending aorta and the pulmonary artery either by direct puncture or through in- cision.Additional tracings were recorded when aortic stenosis and pulmonary stenosis had been artificially created.In the remaining two dogs, the phonocatheter being inserted through jugular vein,tracings from right heart were recorded only. All the intracardiac phonocardiographic tracings were carefully analyzed and compared with those ordinary phonocardiograms.The results are presented in detail. The authors believe that:(1) intracardiac phonocardiogram which has been obtained in each heart chamber or great vessel reflects the heart sound produced there;(2) the 2nd com- ponent of the 1st heart sound is likely produced by closure of the atrioventricular valves,while the 3rd component is produced by opening of the semilunar valves;(3) there is always a systolic murmur in the pulmonary artery;(4)cardiac murmur is transmitted in the direction of blood flow,and is not transmitted in the opposite direction of blood flow;(5)when intracardiac phonocardiogram is recorded care is taken not to include the sound produced by friction bet- ween microphone and endocardial surface of the heart.

    本文报告应用国产微型心音图微音器,通过心脏插管检查,进行人及狗心腔内心音图检查的结果。认为此微音器可以记录人的一侧心脏腔内的心音,对杂音的起源有定位作用,是诊断心脏病中的一项有价值的工具。文中对10例正常人右心各腔与10只狗左右心各腔的心音图进行分析,并就正常人右心各腔心昔图的特点、第一音的第二、三部分的发生机制、心腔内杂音的传播情况以及本检查应注意的事项等方面,加以讨论。

     
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