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hepatitis cirrhosis    
相关语句
  肝硬化
    (4) To compare the expression of CD34, CD31 and Ki-67 among normal liver, chronic hepatitis, cirrhosis, HCC and liver metastatic adenocarcinoma and search for valuable markers to distinguish different diseases in liver.
    (4)比较正常肝组织、慢性肝炎、肝硬化、肝细胞肝癌组织及肝转移腺癌中CD34、CD31、Ki-67不同表达,寻找有助于鉴别不同性质病变的生物学标记物。
短句来源
    (4) The median levels of TPS in patients with hepatitis, cirrhosis,HCCare 77.5 uIl,166.91 uIl,299.06 uIl,respectively.
    (4)肝炎、肝硬化、肝癌病人的中位TPS水平分别为77.5u/l、 166.91u/l、299.06u/l;
短句来源
    The positive ratesof TPS in the three groups of hepatitis,cirrhosis,HCC are 40.0%(8/20),70.0%(21/30), 89.6%(86/96),and AFP 10.0% (2/20),26.7%(8/30), 73.0%(70/96),respectively.
    56.32ng/ml。 以TPS≥80 u/l为诊断肝癌标准,TPS在肝炎、肝硬化、肝癌的阳性率分别为40.0%(8/20)、70.0%(21/30)、89.6%(86/96);
短句来源
    The serum CⅣ levels in normal controls, acute hepatitis, chronic hepatitis, cirrhosis and hepatocellular carcinoma were 78±8, 93±12, 111±30, 130±22, 131±32 μg/L,respectively.
    正常对照组(65例)、急性肝炎(10例)、慢性肝炎(19例)、肝硬化(14例)和原发性肝癌合并肝硬化组(30例),血清CⅣ浓度分别为78±8,93±12,111±30,130±22和131±32μg/L。
短句来源
    Methods south- ern hybridization was used to detect HBV DNA integration in vinous kinds of liver tissues, and DNA-RNA in situ hybrid- ization to observe and analyze the mRNA of IGF- n and IGF- n receptor in chronic hepatitis, cirrhosis and hepatocellular carcinoma(HCc).
    方法通过 DNA、 RNA原位分子杂交和 Southern杂交技术,观察和分析慢性肝炎、肝硬化和肝癌中 IGF- Ⅱ, IGF- Ⅱ R基因的单细胞转录水平的表达与 HBV DNA整合之间的关系。
短句来源
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  肝炎后肝硬化
    Methods Nine patients with hepatic carcinoma in segment Ⅷ were studied. All patietnshad post hepatitis cirrhosis. Their liver function was: Child A in 7 patients and Child B in 2 patietns.
    方法回顾总结9例第Ⅷ段肝癌手术切除的经验,9例患者均伴有肝炎后肝硬化,术前肝功能,ChildA级7例,ChildB级2例。
短句来源
    Method Retrospective analysis of clinical data of 14 cases of central hepatectomy for hepatocellular carcinoma, all cases had post hepatitis cirrhosis with liver function of Child A in 11 cases and Child B in 3 cases.
    方法回顾性分析14例中央二区肝细胞癌切除的临床资料,14例肝细胞癌患者均伴有肝炎后肝硬化,术前肝功能,ChildA11例,ChildB3例。
短句来源
  肝炎肝硬变
    CLINICAL ANALYSIS OF 18 CASES OF PRIMARY HEPATIC CARCINOMA INITIALLY MISDIAGNOSED AS HEPATITIS CIRRHOSIS
    原发性肝癌初诊误诊肝炎肝硬变18例临床分析
短句来源
    5. AKP,γ—GT increased continually and AFP was higher than nomal in hepatitis cirrhosis patients.
    5)肝炎肝硬变患者AKP、γ—GT持续增高,AFP持续高于正常值。
短句来源
    18 cases of primary hepatic carcinoma were initially, misdignosed as hepatitis cirrhosis from 1985 to 1995. When contrasting with 18 hepatitis cirrhosis patients, hospitalized at same period and with same age and sex, we suggested that more attention should be paid to the following points. 1. Hepatosplenomegaly with sclerotic nature nodular surface and sustained right epigastralgia (P<001).
    1985~1995年间初诊误诊肝炎肝硬变(HLC)的原发性肝癌18例,与配对抽取同期住院,性别、年龄相同的肝炎肝硬变18例,将其临床表现、病毒性肝炎血清标志、生化及AFP检测,以及B超、CT扫描影像学检查等进行对比分析,有以下鉴别注意点:1)肝脾肿大质地硬或呈结节状,持续性右上腹痛(P<001)。
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  hepatitis cirrhosis
The common causes of hepatomegaly were found to be infective hepatitis cirrhosis of the liver and tuberculer granulomatous hepatitis.
      


The changes of 10 kinds of trace elements in blood were serially observed by ICP method in rats with hepatitis cirrhosis and hepato cellular carcinoma. Rats were fed with DABfood for 26 weeks Ten 10 kinds of trace elements in blool were detected by ICP method in rats at the stage of hepatitis (8th week) and cirrhosis (18th week) and hepatocarcinoma (26th week) respectively. The results showed that at the stage of hepatitis cellular Mn lerel in experimental group was significantly lower...

The changes of 10 kinds of trace elements in blood were serially observed by ICP method in rats with hepatitis cirrhosis and hepato cellular carcinoma. Rats were fed with DABfood for 26 weeks Ten 10 kinds of trace elements in blool were detected by ICP method in rats at the stage of hepatitis (8th week) and cirrhosis (18th week) and hepatocarcinoma (26th week) respectively. The results showed that at the stage of hepatitis cellular Mn lerel in experimental group was significantly lower than that in contral group (p<0.05). At the stage of cirrhosis lerels of Mn,Ba,Fe,Si,Zn and Se were lower (P<0.05~0.001) and that of Cu was higher (P<0.001) in experimental group than that in contiol group. At the stage of carcinoma Mn. Ba,Fe,Si,Zn,Se and Mo levels were lower (P<0.05~0.001) and the Cu and Cr were higher (P<0.001) in experimental group than that in contiol group, results indicated that the more severe hepatic disease the more obvious alterations of the trace elements, and the trace elements Se,Zn,Mn,Si,Fe,Mo and Ba may be beneficial to prevention of liver cirrhosis and hepato cellnlar carcinoma.

本文系列观察了DAB诱发肝炎、肝硬变和肝癌大鼠血中10种微量元素变化及其变化规律。给予Wistar大鼠喂养DAB饲料26周。在实验第8周(肝炎期)、18周(肝硬变期)和26周(肝癌期)分别检测6只肝炎、肝硬变和肝癌大鼠血中10种微量元素。结果显示:肝炎时仅Mn低于正常组(P<0.005);肝硬变时Mn、Ba、Fe、Si、Zn和Se均显著低于正常组(P<0.05~0.001),Cu显著高于正常组(P<0.001);肝癌时Mn、Ba、Fe、Si、Zn、Se和Mo均显著低于正常组(P<0.05~0.001),Cu和Cr显著高于正常组(P<0.001)。结果表明:1.肝病越重,微量元素变化越明显;2.Se、Zn、Mn、Si、Fe、Mo和Ba可能对肝硬变和肝癌有预防作用。

Transforming growth factor β 1 (TGF β 1) is an important mediator of control of liver cell proliferation and differentiation. The aim of the current study was to compare TGF β 1 expression in neoplastic human livers and normal liver beside neoplasm. Twelve resections for hepatocellular carcinoma were included in this study. TGF β 1 protein were detected on serial tissue sections using immunohistochemistry. The results were analysed by computerized image analysis system. In liver beside neoplasm, TGF...

Transforming growth factor β 1 (TGF β 1) is an important mediator of control of liver cell proliferation and differentiation. The aim of the current study was to compare TGF β 1 expression in neoplastic human livers and normal liver beside neoplasm. Twelve resections for hepatocellular carcinoma were included in this study. TGF β 1 protein were detected on serial tissue sections using immunohistochemistry. The results were analysed by computerized image analysis system. In liver beside neoplasm, TGF β 1 was significantly expressed. The amount of positive area was respectively (9.96±10.7)% and (56.6±26.62)% ( P <0.01). Plasma TGF β 1 levels in patients with HCC ( n =15) were compared with those in patients with viral hepatitis cirrhosis ( n =14) and in normal subjects ( n=10 ) using an enzyme linked immunosorbent assay system. Normal subjects and the patients with cirrhosis had significantly higher plasma TGF β 1 levels [(182.92±90 45)μg/L and (119.53±87.73)μg/L] than those in patients with HCC [(62.37±51.52)μg/L] ( P <0.01). This study suggest that the decrease expression of TGF β 1 by tumoral hepatocytes might be related to its transformation and unlimited proliferation.

用LSAB法对12例肝细胞癌病人手术切除标本进行转化生长因子-β1(TGF-β1)免疫染色,经计算机图象分析系统分析,发现肝癌组织的TGF-β1表达明显低于癌旁肝组织,阳性染色面积(相对数),肝癌与癌旁肝组织分别为(9.96±10.7)%和(56.6±26.62)%(P<0.01)。此外,外周血TGF-β1水平测定(SELISA法)发现,健康志愿者组和肝硬化病人组外周血TGF-β1水平明显高于肝癌病人(未治疗组),3组分别为(182.92±90.45)μg/L,(119.53±87.73)μg/L和(62.37±51.52)μg/L(P<0.01和P<0.05);本研究提示肝癌细胞TGF-β1表达降低可能与其细胞的转化和生长失控有关,也是其生物学特征之一。

In order to investigate changes of serum soluble interleukin 6 receptor(sIL 6R) and soluble gp130(sgp130)in patients with hepatitis cirrhosis(HC) and its clinical significance,the concentrations of serum sIL 6R and sgp130 were determined by using enzyme linked immunosorbent assay in 34 cases patients with HC.The results showed ① The serum sIL 6R and sgp130 le vels in patients with HC were higher than normal controls( P < 0.01 ).Patients...

In order to investigate changes of serum soluble interleukin 6 receptor(sIL 6R) and soluble gp130(sgp130)in patients with hepatitis cirrhosis(HC) and its clinical significance,the concentrations of serum sIL 6R and sgp130 were determined by using enzyme linked immunosorbent assay in 34 cases patients with HC.The results showed ① The serum sIL 6R and sgp130 le vels in patients with HC were higher than normal controls( P < 0.01 ).Patients with active HC had a higher sIL 6R and sgp130 levels than those with silence HC( P <0.01).The ratio of serum sIL 6R and sgp130 was decreased in HC and was lower in active HC than in silence HC.②Serum sIL 6R levels had positive correlation with serum gp130 levels( r =0.417, P <0.05).Serum sIL 6R and sgp130 le vels in patients with HC had positive correlation with serum totle bilirubin(Bil T),respectively( r =0.474, r = 0.482 , P <0.01),but not with serum alanine aminotransferase(ALT)( r =0.193; r =0.152, P >0.05).Serum sIL 6R and sgp130 may be related to the evolution of disease in patients with HC.

为了解胃癌组织中谷胱甘肽S-转移酶-π(GST-π)表达的临床意义,运用流式细胞技术,对75例胃癌组织及癌旁粘膜组织中GST-π的表达进行了检测;同时用免疫组化法检测胃癌组织中C-erbB-2蛋白和nm23蛋白。结果:不同病理类型胃癌组织中GST-π的表达无差异(P>0.05)。75例胃癌组织中GST-π表达水平与癌旁粘膜组织中GST-π水平有统计学差异(t=17.44P<0.01),而GST-π的含量不受C-erbB-2蛋白及CEA含量的影响(P>0.05)。结论:胃癌组织中GST-π的表达增强,与胃癌细胞生理适应特性有关,亦与胃癌细胞抗化疗药物有关

 
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