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bupivacaine
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  布比卡因
    METHODS:40 cases of patients aged 1-6 years old,who were going to be operated in hypogastrium,perineum and lower limb,were randomly and double-blindly divided into four groups with ten cases each:control group(bupivacaine 2.5 mg/kg),low dosage group(ropivacaine 2.5 mg/kg),middle dosage group(ropivacaine 3.5 mg/kg)and high dosage group(ropivacaine 5.0 mg/kg).
    方法:40例1~6岁行下腹部、会阴部及下肢手术患儿,随机双盲分成布比卡因(2.5mg/kg)对照组,罗哌卡因低、中、高(2.5、3.5、5.0mg/kg)剂量组。
短句来源
    Clinical study of using ropivacaine and bupivacaine for spinal anesthesia in children
    罗哌卡因与布比卡因用于小儿硬膜外麻醉的临床研究
短句来源
    Application of ropivacaine 0.5% with bupivacaine 0.5% for spinal anaesthesia in children
    0.5%罗哌卡因与0.5%布比卡因在小儿脊麻中的应用
短句来源
    The block was performed under basic anesthesia. Solutions of lidocaine and/or bupivacaine(with 1 : 200,000 epinephrine) were injected in volumes ranged from 0. 5 to 1. 5ml/kg.
    在基础麻醉下,三种不同浓度的利多卡因和/或布比卡因,分别以0.5~1.25ml/kg(含肾上腺素1:200.000)容积注入骶管腔内。
短句来源
    Group A(n=2)were administrated with 5ml of 1 5mg/kg tramadol and 0 125% bupivacaine through epidural catheter.
    A组 (n =2 0 )曲马多 1 5mg/kg + 0 12 5 %布比卡因的镇痛液 5ml,B组 (n =2 0 )曲马多 1mg/kg + 0 12 5 %布比卡因的镇痛液 5ml;
短句来源
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  丁哌卡因
    Conclusion 5μg·kg -1 ·h -1 morphine mixed with 0.125% bupivacaine epidurally administered at the rate of 0.5 ml·h -1 is a safe and effective method for pediatric patient postoperative analgesia.
    结论 吗啡 5μg· kg- 1 · h- 1 复合 0 .12 5 %丁哌卡因硬膜外持续注入是儿童较为安全有效的术后镇痛方法之一。
短句来源
    BUPIVACAINE USED FOR PEDIATRIC POSTOPERATIVE EPIDURAL ANALGESIA
    丁哌卡因用于小儿硬膜外术后镇痛
短句来源
    Tetracaine (group 1 ), bupivacaine (group 2 and 3)and lidocaine (group 4)were compared in subarachnoid block for children.
    采用地卡因(Ⅰ组)、丁哌卡因(Ⅱ、Ⅲ组)及利多卡因(Ⅳ组)用于5~12岁小儿蛛网膜下腔阻滞进行临床分析比较。
短句来源
    Objective To evaluate the effects and safety of morphine combined with 0.125% bupivacaine continuous epidural injection for postoperative analgesia in pediatric patients.
    目的 评价硬膜外吗啡 5μg· kg- 1 · h- 1 复合 0 .12 5 %丁哌卡因持续注入对儿童术后镇痛的效果及安全性。
短句来源
    Methods Twenty three pediatric patients,ASA class Ⅰ Ⅱ, received selective abdominal or lower extremity surgery,and epidural combined with general anesthesia were performed. After operation 5μg·kg -1 ·h -1 morphine mixed with 0.125% bupivacaine was epidurally infused at the rate of 0.5 ml·h -1 ,the analgesic effect and side effects were recorded,blood pressure,heart rate,respiratory rate and pulse oxygen saturation were monitored.
    方法 选 ASA ( ~ )级择期腹部或下肢手术的患儿 2 3例 ,行硬膜外复合全麻 ,术毕以 0 .12 5 %丁哌卡因及吗啡 5μg· kg- 1 · h- 1 按 0 .5 ml· h- 1 的速率硬膜外腔持续注入 ,观察镇痛效果及副作用 ,监测血压、心率、呼吸频率及脉搏氧饱和度。
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  “bupivacaine”译为未确定词的双语例句
    2% lidocaine and 0.5% bupivacaine mixture with epinephrine 1∶200,000 was used as local anesthetics,average doses of drugs was 14.3±4.8ml, if children not cooperation the ketamine 4-6mg/kg was intramuscular before into room,and the intravenous administration of midazolam 0.15-0.3mg/kg and ECG,MAP,HR,RR,SpO 2 were monitored during operation.
    不合作者肌注氯胺酮 4- 6mg/kg后再行静脉和肌间沟穿刺。 术中常规静脉滴入咪唑安定 0 .15 - 0 .3mg/kg维持麻醉 ,麻醉期间连续监测心电图 (ECG)、血压 (MAP)、心率(HR)、脉搏氧饱和度 (SpO2 )和呼吸频率 (RR)变化 ,手术历时 2 - 11小时。
短句来源
    For intra - and postoperative analgesia caudal block with 0.5 - 1 .0mL/kg 0.25% plain bupivacaine and topical initration with 3 - 5mL 1% lidocaine were provided for all patients.
    术中、术后止痛用0.25~1.0mL/kg实施骶麻,1%利多卡因3~5mL实施局麻。
短句来源
    Methods Sixty 2-6 years - old children undergoing inguinal hernia repair were randomly divided into two groups: ropivacaine group (group r, n=30) and bupivacaine group (group B, n = 30) .
    方法 60例2~6岁腹股沟斜疝择期手术的幼儿,随机分为R组和B组,每组30例。
短句来源
    Objective To evaluate the clinical safety and efficacy of 0.5% ropivacaine for spinal anesthesia and compare with 0.5%bupivacaine in children.
    目的观察 0 .5 %罗哌卡因应用于小儿脊麻中的安全性和有效性。
短句来源
    Motor block with ropivacaine was recorded earlier than that with bupivacaine(P<0.05).
    运动神经阻滞评分两组间差异比较有显著意义(P<0.05)。
短句来源
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  bupivacaine
Effects of levobupivacaine and bupivacaine on rat myometrium
      
Objective: To study the effect of levobupivacaine and bupivacaine on the contractility of isolated uterine muscle strips from pregnant and non-pregnant female rats.
      
In the myometrium from non-pregnant rats,-logIC50 of levobupivacaine and bupivacaine were 4.85 and 4.25 respectively.
      
In the myometrium from pregnant rats, similar concentrations of levobupivacaine and bupivacaine were observed,-logIC50 were 2.7 and 2.9 respectively.
      
Levobupivacaine produced an increase in amplitude of contractions, while bupivacaine showed an increased trend in frequency.
      
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Tetracaine (group 1 ), bupivacaine (group 2 and 3)and lidocaine (group 4)were compared in subarachnoid block for children. The results showed that the onset of four groups was no significant difference (P > 0. 05 ). The fixed time of block level was compared,group 1 and group 2 slower than group 3 and group 4(P< 0. 05). The disapperance of block level was the slowest in group 1 (P<0. 01 ). and there were no significant difference among the others (P > 0. 05). It is concluded that tetracaine and bupivacaine...

Tetracaine (group 1 ), bupivacaine (group 2 and 3)and lidocaine (group 4)were compared in subarachnoid block for children. The results showed that the onset of four groups was no significant difference (P > 0. 05 ). The fixed time of block level was compared,group 1 and group 2 slower than group 3 and group 4(P< 0. 05). The disapperance of block level was the slowest in group 1 (P<0. 01 ). and there were no significant difference among the others (P > 0. 05). It is concluded that tetracaine and bupivacaine seems to be a good local anesthetic for spinal anesthesia for children, but lido- caine is not suitable.

采用地卡因(Ⅰ组)、丁哌卡因(Ⅱ、Ⅲ组)及利多卡因(Ⅳ组)用于5~12岁小儿蛛网膜下腔阻滞进行临床分析比较。结果显示不同局麻药在阻滞作用开始时间无统计学差异(P>0.05),阻滞平面固定时间Ⅰ组与Ⅱ组长于Ⅲ组与Ⅳ组(P<0.05),阻滞平面消退时间Ⅰ组明显长于其它三组(P<0.01),而三组间无明显差异(P>0.05)。结果提示地卡因、丁哌卡因适用于小儿蛛网膜下腔阻滞,利多卡因不宜选用。

The suceess rate and adverse effects and the relationship between volumes and effects of pediatric caudal an-erthesia were reported in a retrospective study of 827 pediatric cases. The block was performed under basic anesthesia. Solutions of lidocaine and/or bupivacaine(with 1 : 200,000 epinephrine) were injected in volumes ranged from 0. 5 to 1. 5ml/kg. The success rate was 96% ,but in the chikdren over 7 years was 88%. The anesthetic onset time and the extent analgesia level were positively corrlated...

The suceess rate and adverse effects and the relationship between volumes and effects of pediatric caudal an-erthesia were reported in a retrospective study of 827 pediatric cases. The block was performed under basic anesthesia. Solutions of lidocaine and/or bupivacaine(with 1 : 200,000 epinephrine) were injected in volumes ranged from 0. 5 to 1. 5ml/kg. The success rate was 96% ,but in the chikdren over 7 years was 88%. The anesthetic onset time and the extent analgesia level were positively corrlated with the characteristics of the local anesthetics and the volumes injected. However,the final extent of sensory blockade varied widely from one patient to another with the same body weight-related volumes. Five cases had local anesthetic toxity, sixteen cases appeared respiratory depression. The SpO2 remained in 98?% and there was no significant hemodynamic changes.

本文回顾性总结827例不同年龄组小儿骶管麻醉(PCA)之成功率、并发症及量效关系。在基础麻醉下,三种不同浓度的利多卡因和/或布比卡因,分别以0.5~1.25ml/kg(含肾上腺素1:200.000)容积注入骶管腔内。结果:成功率为96%,起效时间和阻滞范围分别与局麻药性质、容积相关。然而相同的公斤体重容积在不同的个体中其阻滞范围存在差异,5例发生局麻药中毒,16例发生呼吸抑制,其余SpO_2维持在98±1%,术中亦无明显的血流动力学改变。

Objective To evaluate the effects and safety of morphine combined with 0.125% bupivacaine continuous epidural injection for postoperative analgesia in pediatric patients.Methods Twenty three pediatric patients,ASA class Ⅰ Ⅱ, received selective abdominal or lower extremity surgery,and epidural combined with general anesthesia were performed.After operation 5μg·kg -1 ·h -1 morphine mixed with 0.125% bupivacaine was epidurally infused at...

Objective To evaluate the effects and safety of morphine combined with 0.125% bupivacaine continuous epidural injection for postoperative analgesia in pediatric patients.Methods Twenty three pediatric patients,ASA class Ⅰ Ⅱ, received selective abdominal or lower extremity surgery,and epidural combined with general anesthesia were performed.After operation 5μg·kg -1 ·h -1 morphine mixed with 0.125% bupivacaine was epidurally infused at the rate of 0.5 ml·h -1 ,the analgesic effect and side effects were recorded,blood pressure,heart rate,respiratory rate and pulse oxygen saturation were monitored.Results No pain and light pain rate was 22/23(95.65%),moderate pain rate was 1/23(4.35%). Blood pressure,heart rate and respiratory rate remained unchanged,no severe respiratory depression or other severe side effect occurred.Conclusion 5μg·kg -1 ·h -1 morphine mixed with 0.125% bupivacaine epidurally administered at the rate of 0.5 ml·h -1 is a safe and effective method for pediatric patient postoperative analgesia.

目的 评价硬膜外吗啡 5μg· kg- 1 · h- 1 复合 0 .12 5 %丁哌卡因持续注入对儿童术后镇痛的效果及安全性。方法 选 ASA ( ~ )级择期腹部或下肢手术的患儿 2 3例 ,行硬膜外复合全麻 ,术毕以 0 .12 5 %丁哌卡因及吗啡 5μg· kg- 1 · h- 1 按 0 .5 ml· h- 1 的速率硬膜外腔持续注入 ,观察镇痛效果及副作用 ,监测血压、心率、呼吸频率及脉搏氧饱和度。结果 术后无痛及轻微痛的患儿 2 2 /2 3(95 .6 5 % ) ,中度痛 1/ 2 3(4.35 % ) ,血压、心率、呼吸频率稳定 ,无明显呼吸抑制 ,恶心、呕吐发生率较低 (分别为 17.39%、8.70 % )。结论 吗啡 5μg· kg- 1 · h- 1 复合 0 .12 5 %丁哌卡因硬膜外持续注入是儿童较为安全有效的术后镇痛方法之一。

 
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