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  急性淋巴细胞白血病
    IMPROVEMENT OF VDCP REGIMEN FOR TREATMENT OF 42 CASES WITH ALL
    改良VDCP方案治疗急性淋巴细胞白血病42例
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    Results:In 46 ALL patients,positive rate of myeloid surface antigens CD13,CD33 were 26.1 % and 21.7 %.
    在急性淋巴细胞白血病中CD13,CD33阳性率分别为26.1%,21.7%;
短句来源
    The results indicated that the positive rate of survivin gene in 37 leukemia patients was 67.6% (25/37) and significantly higher than that in normal control (20.0%). The expression level was higher in ALL cells than that in AML cells (73.3% vs 63.6%).
    结果显示:37例白血病患者中有25例表达survivin,阳性率为67.6%,其中急性淋巴细胞白血病(ALL)细胞中survivin mRNA表达阳性率为73.3%,高于急性髓系白血病(AML),但均高于正常对照组(20.0%)(P<0.05)。
短句来源
    Methods Expression of WT1 was measured in 56 acute leukemia children and 12 control children by RT-PCR method. Expression of bcl-2 was measured in 40 ALL children by immunofluorescence flow cytometry.
    方法应用逆转录-聚合酶链反应(RT-PCR)方法测定56例急性白血病患儿及12例对照患儿的WT1基因表达,同时采用免疫荧光流式细胞术观察40例急性淋巴细胞白血病(ALL)患儿抗凋亡基因bcl-2的表达。
短句来源
    OBJECTIVE:To investigate the association of aberrations of chromosome 21 with trisomies 4, 10 and 17 in patients with acute lymphoblastic leukemia (ALL) and to determine their clinical significance of those findings.
    目的:探讨急性淋巴细胞白血病(a-cute lymphoblastic leukemia,ALL)患者21号染色体畸变与4、10、17号染色体三倍体的相关性及其临床意义。
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    Effect of All trans Retinoic Acid on the Formation of Normal Hematopoietic Progenitor Cell Colony
    维甲酸对正常造血祖细胞集落形成的影响
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    PRELIMINARY STUDY ON THE EFFECT AND SAFETY OF McAb 3A1-DAUNOMYCIN IMMUNOCONJUGATE IN CLINICAL TREATMENT OF ALL
    3A1-柔红霉素对急性T细胞白血病的效果与安全性初探
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    COMBINED EFFECTS OF SODIUM SELENITE AND ALL TRANS RETINOIC ACID ON DNA AND PROTEIN SYNTHESES AND CELL CYCLE OF HUMAN PROMYELOCYTIC LEUKEMIA CELLS(HL 60)
    亚硒酸钠和维甲酸联合对HL-60细胞DNA与蛋白质合成和细胞周期的影响
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    Results Of all the 18 cases,11 cases are male,7 cases are female,male:female=1.6:1,patients age.
    结果本组18例中,男11例,女7例,男女之比为1.6∶1。
短句来源
    Among all the cases,15 patients were treated by surgical treatment,9 cases chose radical resection which the overall survival rates were 44.4% at 2 years and 22.2% at 5 years;
    15例外科手术治疗,其中行根治术9例,术后2年生存率44.4%(4/9),5年生存率22.2%(2/9);
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  all
In all these cases we actually show that Γ=π1(M) has a finite index subgroup which is mapped onto a nonabelian free group.
      
The aim of the paper is to describe all open subsets of a projective space with an action of a reductive group which admits a good quotient.
      
This allows us to obtain a complete list of all irreducible linear groups with a polynomial ring of invariants.
      
Whenever the action of a maximal torus on the coneCλ* has some nice properties, we obtain simple closed formulas for all weight multiplicities and theirq-analogs in the representationsVnλ,n∈?.
      
As a corollary we obtain an easy proof of a theorem of Borel and Serre: AnS-arithmetic subgroup of a semisimple group has all the finiteness propertiesFn.
      
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This paper reports the results of the clinical use of Corydalis B as an analgesic in 72 patients with various forms of pain. In 64 cases the drug was used in a single dose, usually of 75 mg. by oral route, while in the other 8 cases repeated doses were given orally over a period of 3 to 21 days. The pain was completely abolished or definitely improved in 50 cases (78.1%) of the former group and in all 8 cases of the latter group. The analgesic effect appeared to be most marked in medical cases with dull...

This paper reports the results of the clinical use of Corydalis B as an analgesic in 72 patients with various forms of pain. In 64 cases the drug was used in a single dose, usually of 75 mg. by oral route, while in the other 8 cases repeated doses were given orally over a period of 3 to 21 days. The pain was completely abolished or definitely improved in 50 cases (78.1%) of the former group and in all 8 cases of the latter group. The analgesic effect appeared to be most marked in medical cases with dull pain in the chest or abdomen, as in cases of peptic ulcer and lobar pneumonia. Drowsiness was found as a side-effect in 28% of the cases after a single dose of the drug and in 6 of the 8 cases treated with repeated doses. In no case was any serious toxic action noted. According to the preliminary Observations herein reported, further clinical trial with the use of Corydalis B as an analgesic agent seems warranted.

本文报告72例试用延胡索素乙硫酸盐作为鎮痛剂的临床观察,其中64例为单剂用药,主要为一次口服75毫克,另8例为长期口服。单剂用药64例中完全止痛及疼痛减轻者共50例,占78.1%,长期服药8例均有效,鎮痛作用在内科胸腹部鈍痛病例较著。用药后未見重要副作用,单剂用药者28%发生嗜睡。长期用药的8例中6例有嗜睡,血与尿常規、大便次数、血压、心率等均无明显改变。据本文病例的初步临床应用结果,延胡索素乙对钝痛有一定的镇痛效果值,得进一步试用。

A comparative study of phosphate-activated glutaminase activity has been conducted in some normal and tumour tissues. It was found that:(1) There was a wide range of difference in the glutaminase activity among the tumours so far investigated, which was however not as wide as that observed in the normal tissues. The highest level of glutaminase activity was found in the transplanted thymolymphosarcoma, which was about seven times higher than that in the normal thymus.(2) During the growth of transplanted solid...

A comparative study of phosphate-activated glutaminase activity has been conducted in some normal and tumour tissues. It was found that:(1) There was a wide range of difference in the glutaminase activity among the tumours so far investigated, which was however not as wide as that observed in the normal tissues. The highest level of glutaminase activity was found in the transplanted thymolymphosarcoma, which was about seven times higher than that in the normal thymus.(2) During the growth of transplanted solid tumours, the glutaminase activity was found to vary with the weight of tumour tissue. An approximate parallelism between the increase in glutaminase activity and the weight of tumour has been observed in some, but not all of the tumours so far studied.(3) The enzyme activity in the regenerating rat liver was lower than that in the normal liver.(4) The possible significance of glutaminase to the growth of some tumours has been discussed.

(1) 本实验比较了一些正常组织与癌瘤组织中谷氨酰胺酶活性。结果发现移植性癌瘤的酶活性以淋巴肉瘤最高。肿瘤间酶活性的变动范围不如正常组织间的变动范围大。诱发性淋巴肉瘤的酶活性较其来源组织为高,但皮肤癌则较正常表皮低。(2) 在肿瘤生长过程中,谷氨酰胺酶活性随肿瘤的重量而有所变化,如艾氏腹水癌(实质型)、脑瘤22、胸腺淋巴肉瘤等的谷氨酰胺酶活性有随肿瘤生长而升高的趋势,但这并不是肿瘤的一般规律,如脑瘤53、Walker癌、肉瘤180等则无此现象。(3) 再生肝的谷氨酰胺酶活性较正常肝低。(4) 讨论了谷氨酰胺酶与某些肿瘤生长的可能关系。

The chemical composition and the enzymatic activities of normal and silicotic alveolar macrophages were compared in order to investigate the changes occurring after the introduction of quartz into the lung. As shown from the SDS-PAGE results, the protein composition of the silicotic alveolar macrophages was different from the normal in three places. Two protein lines showed increased intensity and one protein line was absent from the gel of the silica containing cells.The lecithin and lysolecithin contents were...

The chemical composition and the enzymatic activities of normal and silicotic alveolar macrophages were compared in order to investigate the changes occurring after the introduction of quartz into the lung. As shown from the SDS-PAGE results, the protein composition of the silicotic alveolar macrophages was different from the normal in three places. Two protein lines showed increased intensity and one protein line was absent from the gel of the silica containing cells.The lecithin and lysolecithin contents were both increased in the silicotic macrophages. The presence of an increased amount of lysolecithin may indicate that the cells were destroyed by the quartz.The acid phosphatase actvity and the oxygen consumption of the silica containing cells were both lower than normal cells.After treatment of the silicotic rats with PVNO, the composition and the enzymatic activities of the macrophages were all returned to the normal level. This shows that PVNO protects the alveolar macrophages from destruction by the quartz particles. Other drugs tested also showed some protective effect on the cells.

文中比较了正常大鼠与矽肺大鼠肺泡巨噬细胞中蛋白质与磷脂的组成,以及酸性磷酸酶活性与耗氧量的差别。根据SDS-PAG电泳的结果看到矽肺大鼠肺泡巨噬细胞的蛋白质区带比正常者多两条,但缺少了一条分子量较小的区带。矽肺大鼠肺泡巨噬细胞中含有大量卵磷脂,说明石英能引起肺表面活性物增多。同时,溶血卵磷脂也比正常者明显地增多,酸性磷酸酶活性与耗氧量均比正常者低,这些都说明石英改变了细胞的组成,破坏了细胞的功能。用克矽平(PVNO)治疗过的大鼠肺泡巨噬细胞的化学组成及酶活性都与正常者近似,证明此药能保护巨噬细胞防止被石英破坏。津_5、山梨醇铝等药物对细胞也表现有不同程度的保护作用。

 
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