Methods IGF 1 was assayed in maternal and umbilical cord before term delivery in 38 normal pregnancies(N group), 20 pregnancies with diabetes(DM group) and 15 pregnancies with Macrosomia (M group). To clearify the relation between IGF 1 and neonatal weight and length.
Multi-factors non-conditional logistic regression showed that first gestational age( OR=4.1102, 95% CI:1. 2610-13.3965), family history of DM( OR = 6.6138, 95%CI: 1.3334-32.8063) and pre - pregnancy BMI (OR=16.8227, 95% CI:5.5441-51.0457) were the risk factors of GDM.
PCOS is an etiology unknown disease. The clinical manifestation of metabolic disturbance in PCOS includes overweight or obesity,insulin resistance(IR),impaired glucose tolerance(IGT),type 2 diabetes mellitus(T2DM),lipometabolism disturbance and increased risk of cardiovascular disease.