Conclusions MMP-1,TIMP-1,and TGF-β_1 are closely related to the development of BA hepatic fibrosis. It may he beneficial to the treatment of bili- ary atresia by decreasing the expressions of TIMP-1 and TGF-β_1,or increasing the expression of MMP-1.
2. According to HE and Masson staining , the pathologic change of liver is diversify, such as Liver cells shape changed, showed vacuole, amalgamation, nucleus disintegrated or disappeared and false hepatic lobule which is deficiency of center vein and theshape and size of hepatocyte in the false lobule is different.
C/EBP mRNA abundance was obviously richer in adjacent hepatic tissue than in cancer tissue(P<0.05). This result suggested that C/EBP plays a very important role in establishing and maintaining the differentiated state of liver cells. The result together with other efforts,also suggests that C/EBP may have an anti-proliferative effect on liver neoplastic tissue.
To get an understanding of children hepatic function and the condition of HBsAg carrier, we did a survey of 824 children in four kindergardens in Jiangyang County for ALT,TTT,ZnTT and HBsAg during high peak seasons of hepatitis in 1991.The results showed:one case had high ALT and TTT with signs of hepatitis;
Hepatic glutathione, lipid peroxides, glutathione peroxidase, alcohol dehydrogenase, aldehyde dehydrogenase, glycogen and total protein in liver were also significantly altered.
Picroliv significantly reverted most of the above said altered blood and hepatic parameters in the alcohol-fed male and female rats to almost normal levels.
The results suggest that HCC patients with esophageal varices and hypersplenism should undergo hepatic resection plus esophageal devascularization or splenectomy if radical resection of HCC can be expected.
However, it has been realized that the IVC stent may compromise the hepatic veins and cause catastrophic consequences, thus the indication for IVC stenting should be reevaluated and especially not to be overused.
All patients underwent direct anastomoses of the RHV and the inferior vena cava (IVC), and in 23 cases, reconstruction of the right inferior hepatic vein was also done.