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   infective dose 在 畜牧与动物医学 分类中 的翻译结果: 查询用时:0.009秒
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infective dose
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  感染剂量
    After NDV were inoculated for 72 h,the 50% tissue culture infective dose(TCID 50 )of NDV Ⅰ strain and hemagglutination titer of NDV Ⅳ strain were determined to evaluate the effects of the three components on cellular infectivity of the virus.
    于病毒接种后 72h测定NDVⅠ系的半数组织培养感染剂量 (TCID50 )和NDVⅣ系的血凝效价 ,以评价 3种中药成分对NDV感染细胞的影响。
短句来源
    When infective dose ranged from 0 5 to 3 0×10 4 oocysts per chicken,level of NO 2 increased in a stepwise manner with increasing infective dose.
    在 0 5× 10 4 ~ 3 0× 10 4 个 /只的感染范围内 ,实验鸡血浆亚硝酸盐水平随着感染剂量的增加而升高。
短句来源
    However, the activity was decreased when infective dose was equal to or higher than 3.0×104 oocysts per chicken.
    但感染剂量在等于或高于3.0×104 个卵囊/只时,活性开始下降。
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  “infective dose”译为未确定词的双语例句
    Examine the 50% embryo lethal dose (ELD50) of the strain GX8/99 and the cell-cloned virus separately, and examine the mean tissue culture infective dose (TCID50 ) of the cell-cloned virus .
    对超强毒IBDV GX8/99株原始毒囊毒及其克隆化细胞毒进行ELD50测定,并对克隆化细胞毒进行TCID50测定。
短句来源
    The Szg and Ssq strains had clear cytopathic effect(CPE) on Vero cell, and the 50% tissue culture infective dose were TCID_(50)=10~(-3.925)/0.5ml, TCID_(50)=10~(-3.223)/0.5ml, respectively. Spherical and capsular virus particles were observed in electron microscope in Vero-cultured virus.
    Ssq株和Szg株在Vero细胞上的细胞病变(CPE)明显,对细胞的感染毒力分别为TCID_(50)=10~(-3.925)/0.5ml和TCID_(50)=10~(-3.223)/0.5ml。
短句来源
    The infective dose of 50% tissue culture (TCID50) to H. K. cells was up to 107/0.1ml, that of embryo 108/0.1ml and that of allantoic fluid 102/0.1ml.
    K细胞半数感染量(TCID_(50))达10~7/0.1ml,胚胎为10~6/0.1ml,尿囊液为10~2/0.1ml;
短句来源
    The results showed that the potency was 5.2、(3.6)、2.1、1.0 PD_(50) per dose when using 500、1 000、2 000、4 000 ID_(50)which is the median infective dose as the challenge viral dosage, respectively.
    结果表明 ,分别用 5 0 0ID50 、10 0 0ID50 、2 0 0 0ID50 和 4 0 0 0ID50 的病毒进行攻毒 ,疫苗每头份分别含 5 .2、3.6、2 .1和 1.0个PD50 。
短句来源
    Compared with that in control cells,the anti-IBRS_(2) cells line was able to delay virus-induced cell death by 21 or 27h at an 50% tissue culture infective dose of 2×10~(3)/mL or 4×10~(2)/mL.
    用2×103和4×102TCID50/mL剂量的TGEV感染时,引起细胞死亡的时间分别为21 h和27 h,与对照组相比,抗性细胞系可明显延迟因病毒感染引起细胞死亡的时间。
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  infective dose
Maximum virus yields in MARC-145, P, and L-1 cell clones were 108.5, 103.5, and 102.5 tissue culture infective dose 50 (TCID50)/0.1 ml, respectively.
      
Minimal infective dose of the OSU strain of porcine rotavirus
      
C57BL/6 mice immunized intraperitoneally (i.p.) with an infective dose of JEV were resistant to intracerebral (i.c.) challenge with JEV, whereas most C3H/He mice treated in the same manner died.
      
We studied the minimal infective dose of the gastroenteritis virus, rotavirus.
      
Independent of infective dose within the range examined, the virulent isolate caused fatal clinical disease, whereas the avirulent isolate caused subclinical infection.
      
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1. By cultivating the lapinized hog cholera vaccine virus(LHCV) on pig kidney cells in rolling bottles with increased volume of cultural media(3—4 times more than the amount used in the routine method), the titres in the first and second harvests of vaccine virus were quite similar to those obtained by the routine method. The titres in the second harvest passed most of the tests of 5×10~4 RID/1ml (Rabbit Infective Doses). Results of the tests met entirely the demand for the mass production of vaccine....

1. By cultivating the lapinized hog cholera vaccine virus(LHCV) on pig kidney cells in rolling bottles with increased volume of cultural media(3—4 times more than the amount used in the routine method), the titres in the first and second harvests of vaccine virus were quite similar to those obtained by the routine method. The titres in the second harvest passed most of the tests of 5×10~4 RID/1ml (Rabbit Infective Doses). Results of the tests met entirely the demand for the mass production of vaccine. 2. The method of cultivating hog cholera vaccine virus in rolling bottles around an inclined axis and with deeper culture media(7—8 times more than in the routine method) produced titres in the first and second harvests or in a single harvest(7 days after inoculation) quite similar to those obtained by the routine method.They fitted well the requirements for vaccine production. 3. We also cultivated the LCHV in rolling bottles as cited above but with even much more culture media(8 times more) and additional aerati on. In this case the titres obtained in single harvests(7 days after inoculation)passed most of the 5×10~4RID/1 ml tests also. The data given above suggested that these three methods of cultivation might be applicable in actual vaccine production, with the only consideration that much greater amounts of culture media than used in the routine method of production had to be consumed in these cases. These modifications would much simplify the production of LCHV vaccine.

1、用增加培养液量(3—4倍)旋转法培养猪瘟弱毒细胞疫苗,第一收、第二收病毒收获液的毒价均可达到普通旋转培养法的滴度。二收的绝大多数批次毒价用兔检5万倍通过,符合制苗要求。 2、用深液(培养液量增加7—8倍)倾斜旋转法培养猪瘟弱毒细胞疫苗。第一收与第二收的毒液或培养7天一次全收的毒液,其大多数试验批次毒价均可达到制苗标准。 3、用深液(培养液量增加8倍)倾斜旋转通气法培养猪瘟弱毒细胞疫苗,接毒后培养7天一次全收毒液,大多数批次试验毒价用兔检5万倍通过。符合制苗要求。以上三种培养方法所得资料说明提高猪肾细胞产毒量是明显的,工艺是简便的,在生产上是可行的。对细胞提高繁殖病毒能力的问题进行了某些探索。

Pseudorabies virus can infect chick embryo and reproduce there by way of passing through egg yolk, allantoic cavity, allanto chorion. After infection, various gross lesions appear. The chick embryo inoculated through egg yolk sac and allantoic carity dies in 48-72 hours. In our experiments we found that the toxicity of amniotic fluid (a. f.) of the infected embryo through egg yolk was the highest. The infective dose of 50% tissue culture (TCID50) to H. K. cells was up to 107/0.1ml, that of embryo 108/0.1ml...

Pseudorabies virus can infect chick embryo and reproduce there by way of passing through egg yolk, allantoic cavity, allanto chorion. After infection, various gross lesions appear. The chick embryo inoculated through egg yolk sac and allantoic carity dies in 48-72 hours. In our experiments we found that the toxicity of amniotic fluid (a. f.) of the infected embryo through egg yolk was the highest. The infective dose of 50% tissue culture (TCID50) to H. K. cells was up to 107/0.1ml, that of embryo 108/0.1ml and that of allantoic fluid 102/0.1ml. To the inoculated allantoic cavity,the TCID60 of allantoic and amniotic fluid was 105/0.1ml, and that of embryo was 103/0.1ml.The pathological .changes occured in fifteen different monolayer cells of H.K., M.K, etc and were mainly two types: one was a big fusion or atr-ophic round necrosis in monolayer kidney cells and the other was atrophic round necrois in the cells of chick embryo.After the growth and reproduction of the virus in H.K. cells, the virus titre in the culture fluid, cytoplasm and cell karyoplasm was estimated 108 TCID50/0.1ml.when the virus reproduces continuously from generation to generation, its titre was up to 108 TCID60/0.1ml. The time of the appearence of pathological changes of cells was only 3 hours in comparison of 24 hours before.

牛伪狂犬病病毒(闽A株)能通过鸡胚卵黄囊、尿囊腔、尿囊膜感染和繁殖,并出现不同程度的病变,经卵黄囊、尿囊腔接种的鸡胚,均于48~72小时死亡,死亡率达100%。经卵黄囊接种的鸡胚其羊水含毒量最高,对H.K细胞半数感染量(TCID_(50))达10~7/0.1ml,胚胎为10~6/0.1ml,尿囊液为10~2/0.1ml;经尿囊腔接种的鸡胚,其尿囊液及羊水均为10~5/0.1ml,胚胎为10~3/0.1ml。 该毒株对H.K、M.K等15种单层细胞均可引起细胞致病作用,其病变可分为二种类型:于单层肾细胞上形成聚融合和萎缩圆形坏死,在鸡胚等细胞上形成萎缩圆形坏死。 病毒在H.K细胞上生长繁殖后,经测定在上清液、细胞质、细胞核质中均含有10~6TCID50/0.1ml的毒价。 牛伪狂犬病病毒经H.K细胞连续传代后,对H.K细胞的毒力可达10~8TCID_(50)/0.1ml,出现细胞病变的时间由原来的24小时缩短为3小时。

In order to clarify some problems encountered in immunizing she- ep and goats against Orf (Contagious ecthyma)by the conventional method introduced by Glover,a series of experiments were initiated. The results obtained were as follows.The specific immunity engende- red by the live vaccine infection seemed to appear 7 days after va- ccination,it was well advanced after 15 days and of substantial deg- ree after 30 days.The duration of immunity appeared to be as long as 8 months.There was no improvement on both...

In order to clarify some problems encountered in immunizing she- ep and goats against Orf (Contagious ecthyma)by the conventional method introduced by Glover,a series of experiments were initiated. The results obtained were as follows.The specific immunity engende- red by the live vaccine infection seemed to appear 7 days after va- ccination,it was well advanced after 15 days and of substantial deg- ree after 30 days.The duration of immunity appeared to be as long as 8 months.There was no improvement on both the degree and duration of the existing immunity after revaccination.The minimum immuni- zing dose varied with the infective titers of viruses derived from sca- bs of affected animals,in other words,the minimum immunizing dole is just the minimum infective dose.As to the protective effi- cacy,there were no significant differences between the lip scab and the inside thigh scab.Suckling kids aged from 1—16 days were su- ccessfully vaccinated and found immune to subsequent challenge.An extensive field trial was carried out on a ranch where the disease had long established.No reinfection was observed among the vacci- nated animals.The emergency immunization under isolation conditi- ons could control the spread of Orf in flocks where the disease al- ready broke out.The authors concluded that the immunization with live Orf virus can be recommended for use only on premises where the disease is prevalent,

本文利用羊口疮活毒就羊口疮的免疫特性和免疫方法进行了一系列研究.羊只接种活毒后15日即可产生明显的免疫力,按种后30日开始出现完全的免疫力,免疫持续期长达8个月。活毒对羊只的最小免疫量即为其最小感染量。在免疫持续期内,第二次免疫接种对羊只的免疫力似无明显的加强作用。股内侧皮肤毒和口唇皮肤毒具有相同的免疫作用。1—16日龄幼羔对活毒接种亦可产生免疫力。利用活毒在疫区对10,000余只羊作大规模预防接种收到良好效果。在发病群用活毒进行紧急接种,在隔离的条件下能制止疫情传播。

 
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