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Fulminant hepatitis is fatal in most cases and timely liver transplantation is the only effective treatment.
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In general, it is extremely difficult to treat fulminant hepatitis by conservative regimen, particularly, in cases with rapid progression.
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Emergency adult living-donor liver transplantation is an effective treatment for fulminant hepatitis patients and is relatively safe for donors.
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Construction of shRNA of fulminant hepatitis related gene mfgl2 and investigation of its biological effects in vitro
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He developed fulminant hepatitis with acute liver failure and an acute respiratory distress syndrom (ARDS).
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| Fifty liver biopsies with fulminant hepatitis showing features cf acute and subacute liver necrosis were studied.Only one out of 8 cases of acute liver necrosis and 23 out of 42 cases subacute liver necrosis survived. According to the morphologic features cf the liver,subacute liver necresis was classified into early, middle, and late stage. After treatment for 1～5 months,the follow-up biopsies were done in 12 survivals, 3 cases of early stage subacute liver necrosis showed mild CAH, 5 cases of middle... Fifty liver biopsies with fulminant hepatitis showing features cf acute and subacute liver necrosis were studied.Only one out of 8 cases of acute liver necrosis and 23 out of 42 cases subacute liver necrosis survived. According to the morphologic features cf the liver,subacute liver necresis was classified into early, middle, and late stage. After treatment for 1～5 months,the follow-up biopsies were done in 12 survivals, 3 cases of early stage subacute liver necrosis showed mild CAH, 5 cases of middle stage showed moderate CAH predominantly and 4 cases of late stage showed 2 cases of severe CAH with cirrhosis. The results suggested that these patients survived in the early stage would make recovery of the liver better. | 在临床急性重症及亚急性重症肝炎中,有50例经肝穿活检证实为急性及亚急性肝坏死。8例急性肝坏死中1例存活,42例亚急性肝坏死中有23例存活。按肝坏死的病理发展过程,把亚急性肝坏死分为早、中、后三期,治疗1～5个月后,有12例进行第二次肝穿活检,其中3例亚急性肝坏死早期均显示为轻度慢活肝,5例中期显示以中度慢活肝为主,而4例后期则显示有2例为重度慢活肝伴肝硬化。其结果表明,在亚急性肝坏死早期经治疗存活者,其肝组织修复较好。 | Pathological study of liver needle biopsy was performed in 1173 adult cases during thelast 10 years.Histologically,910 cases were diagnosed as 15 varied liver diseases(LD).Amongthese,the most frequency was chronic active hepatitis(CAH)as high as 48.9%.Patients with acutehepatitis(AH),chronic hepatitis(CH)were more young than that with subacute fulminant hepatitis(SAFH),cirrhosis(Ci)and HCC,the peak of age were 20～29 and 40～49 respectively.Detectionof HBV markers in serum arrd/or liver tissue of patients... Pathological study of liver needle biopsy was performed in 1173 adult cases during thelast 10 years.Histologically,910 cases were diagnosed as 15 varied liver diseases(LD).Amongthese,the most frequency was chronic active hepatitis(CAH)as high as 48.9%.Patients with acutehepatitis(AH),chronic hepatitis(CH)were more young than that with subacute fulminant hepatitis(SAFH),cirrhosis(Ci)and HCC,the peak of age were 20～29 and 40～49 respectively.Detectionof HBV markers in serum arrd/or liver tissue of patients with CH,Ci and HCC was high up to 80%contrasting to 25% in AH and SAFH cases.Morphologic features of AH-A,CAH and double infec-tion were described and discussed. | 从1980年～1989年收集1173例成人肝穿刺标本,经组织病理学确诊了15种肝病共910例,其中慢性活动性肝炎(CAH)为445例,占本文肝病数48.90%为首位。本组肝病发病年龄有2个高峰:急性肝炎(AH),慢性持续性肝炎(CPH),慢性小叶性肝炎(CLH)和CAH为20～29岁组;亚急性重症肝炎(SAFH)和肝硬化(Ci),原发性肝细胞肝癌(PHCC)为40～49岁组。乙肝病毒标记物(HBV-M)检测显示CPH,CLH,CAH,Ci和PHCC阳性率均高于80%,而AH和SAFH则低于25%。本文讨论了急性甲型肝炎,CAH和双重感染的病理特点。 | ABMTs on 4 cases of common-ALL in remission were studied. The bone marrow was purified in vitro by complement mediated cytotoxicity. Three of them remained in complete remission after 42, 35, and 12 months respectively, and one relapsed after 4 month remission. The bone marrow of other 2 cases of Null-ALL and one case of common-ALL was purified in vitro by immunotoxin after their complete remission, and then they were treated by ABMT. Two of them remained in complete remission after 14 and 6 months respectively... ABMTs on 4 cases of common-ALL in remission were studied. The bone marrow was purified in vitro by complement mediated cytotoxicity. Three of them remained in complete remission after 42, 35, and 12 months respectively, and one relapsed after 4 month remission. The bone marrow of other 2 cases of Null-ALL and one case of common-ALL was purified in vitro by immunotoxin after their complete remission, and then they were treated by ABMT. Two of them remained in complete remission after 14 and 6 months respectively and one, after 5 months of remission, died of fulminant hepatitis. | 采取４例处缓解期的普通型急性淋巴细胞白血病患者的骨髓，用补体介导细胞毒法体外净化后进行自体骨髓移植，其中３例分别于移植后４２、３５和１２个月仍处于完全缓解；１例移植后４个月复发。对另外３例经化疗达完全缓解的未分化型（２例）和普通型（１例）急性淋巴细胞白血病患者采取骨髓，用免疫毒素法体外净化后行自体骨髓移植，２例分别于移植后１４和６个月仍处于完全缓解，１例移植后５个月，因患急性重型肝炎死亡，但骨髓仍为完全缓解。体外净化所用的单克隆抗体为ＭｃＡｂ５５、ＪＮ２０５及ＰＨＮ２００。 | | | | << 更多相关文摘 |
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fulminant hepatitis
重型肝炎
查询“fulminant hepatitis”译词为用户自定义的双语例句
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